{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q9CCF6","secondaryAccessions":["O32952"],"uniProtkbId":"Y869_MYCLE","entryAudit":{"firstPublicDate":"2001-08-29","lastAnnotationUpdateDate":"2025-02-05","lastSequenceUpdateDate":"2003-01-10","entryVersion":87,"sequenceVersion":2},"annotationScore":2.0,"organism":{"scientificName":"Mycobacterium leprae (strain TN)","taxonId":272631,"lineage":["Bacteria","Bacillati","Actinomycetota","Actinomycetes","Mycobacteriales","Mycobacteriaceae","Mycobacterium"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized protein ML0869"}}},"genes":[{"orderedLocusNames":[{"value":"ML0869"}],"orfNames":[{"value":"MLCB22.07"}]}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"CAB11372.1","evidences":[{"evidenceCode":"ECO:0000305"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"CAC31250.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":229,"modifier":"EXACT"}},"description":"Uncharacterized protein ML0869","featureId":"PRO_0000103976"},{"type":"Transmembrane","location":{"start":{"value":137,"modifier":"EXACT"},"end":{"value":157,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":159,"modifier":"EXACT"},"end":{"value":179,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":102,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":73,"modifier":"EXACT"},"end":{"value":94,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"11234002","citationType":"journal article","authors":["Cole S.T.","Eiglmeier K.","Parkhill J.","James K.D.","Thomson N.R.","Wheeler P.R.","Honore N.","Garnier T.","Churcher C.M.","Harris D.E.","Mungall K.L.","Basham D.","Brown D.","Chillingworth T.","Connor R.","Davies R.M.","Devlin K.","Duthoy S.","Feltwell T.","Fraser A.","Hamlin N.","Holroyd S.","Hornsby T.","Jagels K.","Lacroix C.","Maclean J.","Moule S.","Murphy L.D.","Oliver K.","Quail M.A.","Rajandream M.A.","Rutherford K.M.","Rutter S.","Seeger K.","Simon S.","Simmonds M.","Skelton J.","Squares R.","Squares S.","Stevens K.","Taylor K.","Whitehead S.","Woodward J.R.","Barrell B.G."],"citationCrossReferences":[{"database":"PubMed","id":"11234002"},{"database":"DOI","id":"10.1038/35059006"}],"title":"Massive gene decay in the leprosy bacillus.","publicationDate":"2001","journal":"Nature","firstPage":"1007","lastPage":"1011","volume":"409"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"TN","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AL583920","properties":[{"key":"ProteinId","value":"CAC31250.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"Z98741","properties":[{"key":"ProteinId","value":"CAB11372.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"T44885","properties":[{"key":"EntryName","value":"T44885"}]},{"database":"AlphaFoldDB","id":"Q9CCF6","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"272631.gene:17574695","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"mle:ML0869","properties":[{"key":"Description","value":"-"}]},{"database":"Leproma","id":"ML0869","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG5031D67","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"HOGENOM","id":"CLU_091328_1_0_11","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000806","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"InterPro","id":"IPR021403","properties":[{"key":"EntryName","value":"DUF3043"}]},{"database":"Pfam","id":"PF11241","properties":[{"key":"EntryName","value":"DUF3043"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKLLGRKKSYGQDIETSDDNVGSEASLPDTLSRGSSTTAPKGRPTRKRDDADRRHTKKGPITPAPMTASEARARRKSLAPPKCHRAERRAKRAASKAQITDRRERMMAGEEAYLPPRDQGPVRRYIRDLVDARRNALGLFTPSALVLLFITFGVPQLQLYMSPAMLVLLSVMGIDGIILGRKISKLVDVKFPSNTESHWRLGLYAAGRASQMRRLRVPRPQVEHGSSVG","length":229,"molWeight":25437,"crc64":"BEDB2E7BF287742E","md5":"5A0550EEA286798A8292C90792CF0923"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SEQUENCE CAUTION":2},"countByFeatureType":{"Chain":1,"Transmembrane":2,"Region":1,"Compositional bias":1},"uniParcId":"UPI000013B88A"}}