{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q99622","secondaryAccessions":["B2R4Q6"],"uniProtkbId":"C10_HUMAN","entryAudit":{"firstPublicDate":"2000-05-30","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1997-05-01","entryVersion":159,"sequenceVersion":1},"annotationScore":5.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Protein C10"}}},"genes":[{"geneName":{"value":"C12orf57"},"synonyms":[{"value":"C10"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23453666"}],"value":"In brain, may be required for corpus callosum development"}],"commentType":"FUNCTION"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q99622","intActId":"EBI-2808472"},"interactantTwo":{"uniProtKBAccession":"Q8NFD2","geneName":"ANKK1","intActId":"EBI-13280688"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q99622","intActId":"EBI-2808472"},"interactantTwo":{"uniProtKBAccession":"P51460","geneName":"INSL3","intActId":"EBI-12919766"},"numberOfExperiments":3,"organismDiffer":false}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23453666"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23453666"}],"value":"Ubiquitously expressed, with higher expression in lung and fetal brain"}],"commentType":"TISSUE SPECIFICITY"},{"commentType":"DISEASE","disease":{"diseaseId":"Temtamy syndrome","diseaseAccession":"DI-03719","acronym":"TEMTYS","description":"An autosomal recessive syndrome characterized by intellectual disability, variable craniofacial dysmorphism, ocular coloboma, seizures, and brain abnormalities, including abnormalities of the corpus callosum and thalamus.","diseaseCrossReference":{"database":"MIM","id":"218340"},"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23453665"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23453666"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23633300"}]},"note":{"texts":[{"value":"The disease is caused by variants affecting the gene represented in this entry. A variant resulting in a GUG start codon may be able to produce some protein because of a consensus Kozak sequence, although less efficiently than the wild type. This would explain the phenotypic variability observed"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the UPF0456 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Initiator methionine","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"Removed","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"19413330"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"22223895"}]},{"type":"Chain","location":{"start":{"value":2,"modifier":"EXACT"},"end":{"value":126,"modifier":"EXACT"}},"description":"Protein C10","featureId":"PRO_0000065034"},{"type":"Modified residue","location":{"start":{"value":2,"modifier":"EXACT"},"end":{"value":2,"modifier":"EXACT"}},"description":"N-acetylalanine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"19413330"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"22223895"}]},{"type":"Natural variant","location":{"start":{"value":51,"modifier":"EXACT"},"end":{"value":51,"modifier":"EXACT"}},"description":"in TEMTYS; dbSNP:rs587776955","featureCrossReferences":[{"database":"dbSNP","id":"rs587776955"}],"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23453665"}],"featureId":"VAR_069774","alternativeSequence":{"originalSequence":"L","alternativeSequences":["Q"]}}],"keywords":[{"id":"KW-0007","category":"PTM","name":"Acetylation"},{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0225","category":"Disease","name":"Disease variant"},{"id":"KW-0991","category":"Disease","name":"Intellectual disability"},{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"9074930","citationType":"journal article","authors":["Ansari-Lari M.A.","Shen Y.","Muzny D.M.","Lee W.","Gibbs R.A."],"citationCrossReferences":[{"database":"PubMed","id":"9074930"},{"database":"DOI","id":"10.1101/gr.7.3.268"}],"title":"Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination.","publicationDate":"1997","journal":"Genome Res.","firstPage":"268","lastPage":"280","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"Brain","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"14702039","citationType":"journal article","authors":["Ota T.","Suzuki Y.","Nishikawa T.","Otsuki T.","Sugiyama T.","Irie R.","Wakamatsu A.","Hayashi K.","Sato H.","Nagai K.","Kimura K.","Makita H.","Sekine M.","Obayashi M.","Nishi T.","Shibahara T.","Tanaka T.","Ishii S.","Yamamoto J.","Saito K.","Kawai Y.","Isono Y.","Nakamura Y.","Nagahari K.","Murakami K.","Yasuda T.","Iwayanagi T.","Wagatsuma M.","Shiratori A.","Sudo H.","Hosoiri T.","Kaku Y.","Kodaira H.","Kondo H.","Sugawara M.","Takahashi M.","Kanda K.","Yokoi T.","Furuya T.","Kikkawa E.","Omura Y.","Abe K.","Kamihara K.","Katsuta N.","Sato K.","Tanikawa M.","Yamazaki M.","Ninomiya K.","Ishibashi T.","Yamashita H.","Murakawa K.","Fujimori K.","Tanai H.","Kimata M.","Watanabe M.","Hiraoka S.","Chiba Y.","Ishida S.","Ono Y.","Takiguchi S.","Watanabe S.","Yosida M.","Hotuta T.","Kusano J.","Kanehori K.","Takahashi-Fujii A.","Hara H.","Tanase T.-O.","Nomura Y.","Togiya S.","Komai F.","Hara R.","Takeuchi K.","Arita M.","Imose N.","Musashino K.","Yuuki H.","Oshima A.","Sasaki N.","Aotsuka S.","Yoshikawa Y.","Matsunawa H.","Ichihara T.","Shiohata N.","Sano S.","Moriya S.","Momiyama H.","Satoh N.","Takami S.","Terashima Y.","Suzuki O.","Nakagawa S.","Senoh A.","Mizoguchi H.","Goto Y.","Shimizu F.","Wakebe H.","Hishigaki H.","Watanabe T.","Sugiyama A.","Takemoto M.","Kawakami B.","Yamazaki M.","Watanabe K.","Kumagai A.","Itakura S.","Fukuzumi Y.","Fujimori Y.","Komiyama M.","Tashiro H.","Tanigami A.","Fujiwara T.","Ono T.","Yamada K.","Fujii Y.","Ozaki K.","Hirao M.","Ohmori Y.","Kawabata A.","Hikiji T.","Kobatake N.","Inagaki H.","Ikema Y.","Okamoto S.","Okitani R.","Kawakami T.","Noguchi S.","Itoh T.","Shigeta K.","Senba T.","Matsumura K.","Nakajima Y.","Mizuno T.","Morinaga M.","Sasaki M.","Togashi T.","Oyama M.","Hata H.","Watanabe M.","Komatsu T.","Mizushima-Sugano J.","Satoh T.","Shirai Y.","Takahashi Y.","Nakagawa K.","Okumura K.","Nagase T.","Nomura N.","Kikuchi H.","Masuho Y.","Yamashita R.","Nakai K.","Yada T.","Nakamura Y.","Ohara O.","Isogai T.","Sugano S."],"citationCrossReferences":[{"database":"PubMed","id":"14702039"},{"database":"DOI","id":"10.1038/ng1285"}],"title":"Complete sequencing and characterization of 21,243 full-length human cDNAs.","publicationDate":"2004","journal":"Nat. Genet.","firstPage":"40","lastPage":"45","volume":"36"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Thymus","type":"TISSUE"}]},{"referenceNumber":3,"citation":{"id":"CI-5GBD0VIIJ7C63","citationType":"submission","authors":["Mural R.J.","Istrail S.","Sutton G.G.","Florea L.","Halpern A.L.","Mobarry C.M.","Lippert R.","Walenz B.","Shatkay H.","Dew I.","Miller J.R.","Flanigan M.J.","Edwards N.J.","Bolanos R.","Fasulo D.","Halldorsson B.V.","Hannenhalli S.","Turner R.","Yooseph S.","Lu F.","Nusskern D.R.","Shue B.C.","Zheng X.H.","Zhong F.","Delcher A.L.","Huson D.H.","Kravitz S.A.","Mouchard L.","Reinert K.","Remington K.A.","Clark A.G.","Waterman M.S.","Eichler E.E.","Adams M.D.","Hunkapiller M.W.","Myers E.W.","Venter J.C."],"publicationDate":"SEP-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":4,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Lung","type":"TISSUE"}]},{"referenceNumber":5,"citation":{"id":"19413330","citationType":"journal article","authors":["Gauci S.","Helbig A.O.","Slijper M.","Krijgsveld J.","Heck A.J.","Mohammed S."],"citationCrossReferences":[{"database":"PubMed","id":"19413330"},{"database":"DOI","id":"10.1021/ac9004309"}],"title":"Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.","publicationDate":"2009","journal":"Anal. Chem.","firstPage":"4493","lastPage":"4501","volume":"81"},"referencePositions":["ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2","CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":6,"citation":{"id":"21269460","citationType":"journal article","authors":["Burkard T.R.","Planyavsky M.","Kaupe I.","Breitwieser F.P.","Buerckstuemmer T.","Bennett K.L.","Superti-Furga G.","Colinge J."],"citationCrossReferences":[{"database":"PubMed","id":"21269460"},{"database":"DOI","id":"10.1186/1752-0509-5-17"}],"title":"Initial characterization of the human central proteome.","publicationDate":"2011","journal":"BMC Syst. Biol.","firstPage":"17","lastPage":"17","volume":"5"},"referencePositions":["IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":7,"citation":{"id":"22223895","citationType":"journal article","authors":["Bienvenut W.V.","Sumpton D.","Martinez A.","Lilla S.","Espagne C.","Meinnel T.","Giglione C."],"citationCrossReferences":[{"database":"PubMed","id":"22223895"},{"database":"DOI","id":"10.1074/mcp.m111.015131"}],"title":"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.","publicationDate":"2012","journal":"Mol. Cell. Proteomics","firstPage":"M111.015131","lastPage":"M111.015131","volume":"11"},"referencePositions":["ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2","CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":8,"citation":{"id":"23453666","citationType":"journal article","authors":["Akizu N.","Shembesh N.M.","Ben-Omran T.","Bastaki L.","Al-Tawari A.","Zaki M.S.","Koul R.","Spencer E.","Rosti R.O.","Scott E.","Nickerson E.","Gabriel S.","da Gente G.","Li J.","Deardorff M.A.","Conlin L.K.","Horton M.A.","Zackai E.H.","Sherr E.H.","Gleeson J.G."],"citationCrossReferences":[{"database":"PubMed","id":"23453666"},{"database":"DOI","id":"10.1016/j.ajhg.2013.02.004"}],"title":"Whole-exome sequencing identifies mutated c12orf57 in recessive corpus callosum hypoplasia.","publicationDate":"2013","journal":"Am. J. Hum. Genet.","firstPage":"392","lastPage":"400","volume":"92"},"referencePositions":["INVOLVEMENT IN TEMTYS","FUNCTION","SUBCELLULAR LOCATION","TISSUE SPECIFICITY"]},{"referenceNumber":9,"citation":{"id":"23633300","citationType":"journal article","authors":["Salih M.A.","Tzschach A.","Oystreck D.T.","Hassan H.H.","Aldrees A.","Elmalik S.A.","El Khashab H.Y.","Wienker T.F.","Abu-Amero K.K.","Bosley T.M."],"citationCrossReferences":[{"database":"PubMed","id":"23633300"},{"database":"DOI","id":"10.1002/ajmg.a.35850"}],"title":"A newly recognized autosomal recessive syndrome affecting neurologic function and vision.","publicationDate":"2013","journal":"Am. J. Med. Genet. A","firstPage":"1207","lastPage":"1213","volume":"161"},"referencePositions":["INVOLVEMENT IN TEMTYS"]},{"referenceNumber":10,"citation":{"id":"23453665","citationType":"journal article","authors":["Zahrani F.","Aldahmesh M.A.","Alshammari M.J.","Al-Hazzaa S.A.","Alkuraya F.S."],"citationCrossReferences":[{"database":"PubMed","id":"23453665"},{"database":"DOI","id":"10.1016/j.ajhg.2013.01.008"}],"title":"Mutations in c12orf57 cause a syndromic form of colobomatous microphthalmia.","publicationDate":"2013","journal":"Am. J. Hum. Genet.","firstPage":"387","lastPage":"391","volume":"92"},"referencePositions":["VARIANT TEMTYS GLN-51"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"U47924","properties":[{"key":"ProteinId","value":"AAB51329.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AK311912","properties":[{"key":"ProteinId","value":"BAG34853.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"CH471116","properties":[{"key":"ProteinId","value":"EAW88705.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC009925","properties":[{"key":"ProteinId","value":"AAH09925.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS8571.1","properties":[{"key":"Description","value":"-"}]},{"database":"RefSeq","id":"NP_001288763.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001301834.1"}]},{"database":"RefSeq","id":"NP_612434.1","properties":[{"key":"NucleotideSequenceId","value":"NM_138425.4"}]},{"database":"AlphaFoldDB","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"125237","properties":[{"key":"Interactions","value":"47"}]},{"database":"FunCoup","id":"Q99622","properties":[{"key":"Number of interactors","value":"672"}]},{"database":"IntAct","id":"Q99622","properties":[{"key":"Interactions","value":"36"}]},{"database":"NDEx","id":"MUSIC2-C5177-C12orf57","properties":[{"key":"Evidences","value":"Osteosarcoma (U2OS) cell map - C5177 (84 proteins)"}]},{"database":"STRING","id":"9606.ENSP00000229281","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"C12orf57","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000229281","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"78363","properties":[{"key":"Description","value":"-"}]},{"database":"Pumba","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"TopDownProteomics","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"22799","properties":[{"key":"antibodies","value":"44 antibodies from 11 providers"}]},{"database":"DNASU","id":"113246","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENST00000229281.6","properties":[{"key":"ProteinId","value":"ENSP00000229281.5"},{"key":"GeneId","value":"ENSG00000111678.12"}]},{"database":"Ensembl","id":"ENST00000545581.5","properties":[{"key":"ProteinId","value":"ENSP00000440602.1"},{"key":"GeneId","value":"ENSG00000111678.12"}]},{"database":"Ensembl","id":"ENST00000852280.1","properties":[{"key":"ProteinId","value":"ENSP00000522339.1"},{"key":"GeneId","value":"ENSG00000111678.12"}]},{"database":"GeneID","id":"113246","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:113246","properties":[{"key":"Description","value":"-"}]},{"database":"MANE-Select","id":"ENST00000229281.6","properties":[{"key":"ProteinId","value":"ENSP00000229281.5"},{"key":"RefSeqNucleotideId","value":"NM_138425.4"},{"key":"RefSeqProteinId","value":"NP_612434.1"}]},{"database":"UCSC","id":"uc001qrz.4","properties":[{"key":"OrganismName","value":"human"}]},{"database":"AGR","id":"HGNC:29521","properties":[{"key":"Description","value":"-"}]},{"database":"ClinPGx","id":"PA143485386","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"113246","properties":[{"key":"Description","value":"-"}]},{"database":"DisGeNET","id":"113246","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"C12orf57","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:29521","properties":[{"key":"GeneName","value":"C12orf57"}]},{"database":"HPA","id":"ENSG00000111678","properties":[{"key":"ExpressionPatterns","value":"Low tissue specificity"}]},{"database":"MalaCards","id":"C12orf57","properties":[{"key":"Description","value":"-"}]},{"database":"MIM","id":"218340","properties":[{"key":"Type","value":"phenotype"}]},{"database":"MIM","id":"615140","properties":[{"key":"Type","value":"gene"}]},{"database":"OpenTargets","id":"ENSG00000111678","properties":[{"key":"Description","value":"-"}]},{"database":"Orphanet","id":"1777","properties":[{"key":"Disease","value":"Temtamy syndrome"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000111678","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502S2W0","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00390000005242","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_144250_1_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"GNDMMKM","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"75738at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"Q99622","properties":[{"key":"Number of GO annotations","value":"1 GO annotation based on evolutionary models"}]},{"database":"PhylomeDB","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"PathwayCommons","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"SignaLink","id":"Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"Agora","id":"ENSG00000111678","properties":[{"key":"NominatedTarget","value":"-"}]},{"database":"BioGRID-ORCS","id":"113246","properties":[{"key":"hits","value":"21 hits in 1133 CRISPR screens"}]},{"database":"ChiTaRS","id":"C12orf57","properties":[{"key":"OrganismName","value":"human"}]},{"database":"GenomeRNAi","id":"113246","properties":[{"key":"Description","value":"-"}]},{"database":"Pharos","id":"Q99622","properties":[{"key":"DevelopmentLevel","value":"Tbio"}]},{"database":"PRO","id":"PR:Q99622","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome 12"}]},{"database":"RNAct","id":"Q99622","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000111678","properties":[{"key":"ExpressionPatterns","value":"Expressed in thymus and 104 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"Q99622","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"23453666"}]},{"database":"GO","id":"GO:0016607","properties":[{"key":"GoTerm","value":"C:nuclear speck"},{"key":"GoEvidenceType","value":"IDA:HPA"}]},{"database":"GO","id":"GO:0048593","properties":[{"key":"GoTerm","value":"P:camera-type eye morphogenesis"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23453665"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23633300"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"24798461"}]},{"database":"GO","id":"GO:0050890","properties":[{"key":"GoTerm","value":"P:cognition"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23633300"}]},{"database":"GO","id":"GO:0021540","properties":[{"key":"GoTerm","value":"P:corpus callosum morphogenesis"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23453665"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23453666"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23633300"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"24798461"}]},{"database":"GO","id":"GO:0009791","properties":[{"key":"GoTerm","value":"P:post-embryonic development"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23453665"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23453666"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23633300"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"24798461"}]},{"database":"GO","id":"GO:0036343","properties":[{"key":"GoTerm","value":"P:psychomotor behavior"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23633300"}]},{"database":"GO","id":"GO:0014819","properties":[{"key":"GoTerm","value":"P:regulation of skeletal muscle contraction"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23453665"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23633300"},{"evidenceCode":"ECO:0000315","source":"PubMed","id":"24798461"}]},{"database":"GO","id":"GO:0021678","properties":[{"key":"GoTerm","value":"P:third ventricle development"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"23453666"}]},{"database":"InterPro","id":"IPR026317","properties":[{"key":"EntryName","value":"Grcc10"}]},{"database":"PANTHER","id":"PTHR13463","properties":[{"key":"EntryName","value":"PROTEIN C10"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR13463:SF3","properties":[{"key":"EntryName","value":"PROTEIN C10"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF14974","properties":[{"key":"EntryName","value":"P_C10"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MASASTQPAALSAEQAKVVLAEVIQAFSAPENAVRMDEARDNACNDMGKMLQFVLPVATQIQQEVIKAYGFSCDGEGVLKFARLVKSYEAQDPEIASLSGKLKALFLPPMTLPPHGPAAGGSVAAS","length":126,"molWeight":13178,"crc64":"111588346C63FC17","md5":"28CADDCC8740EA5991E45D41EC53CD96"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"INTERACTION":2,"SUBCELLULAR LOCATION":1,"TISSUE SPECIFICITY":1,"DISEASE":1,"SIMILARITY":1},"countByFeatureType":{"Initiator methionine":1,"Chain":1,"Modified residue":1,"Natural variant":1},"uniParcId":"UPI0000126B9B"}}