{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q93WG3","secondaryAccessions":["Q8H167","Q8LB27","Q9FRS1"],"uniProtkbId":"CJD1_ARATH","entryAudit":{"firstPublicDate":"2022-02-23","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2001-12-01","entryVersion":147,"sequenceVersion":1},"annotationScore":4.0,"organism":{"scientificName":"Arabidopsis thaliana","commonName":"Mouse-ear cress","taxonId":3702,"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Brassicales","Brassicaceae","Camelineae","Arabidopsis"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"22028775"}],"value":"Protein CHLOROPLAST J-LIKE DOMAIN 1, chloroplastic"}},"flag":"Precursor"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"22028775"}],"value":"CJD1"},"orderedLocusNames":[{"evidences":[{"evidenceCode":"ECO:0000312","source":"Araport","id":"AT1G08640"}],"value":"At1g08640"}],"orfNames":[{"evidences":[{"evidenceCode":"ECO:0000312","source":"EMBL","id":"AAF99779.1"}],"value":"F22O13.12"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22028775"}],"value":"Probably involved in the regulation of the fatty acid metabolic process in chloroplasts, especially chloroplastic galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22028775"}],"value":"Interacts (via J-like domain) with ARC6 (via J domain)"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22028775"}],"value":"Plastid, chloroplast inner membrane","id":"SL-0051"},"topology":{"evidences":[{"evidenceCode":"ECO:0000255"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22028775"}],"value":"Altered fatty acid profiles with a slight increase of 16:1delta7 and 18:1delta9 leaf monounsaturated fatty acids and subtle decrease of 16:3 and 18:3 polyunsaturated fatty acids, chloroplastic galactolipids monogalactosyldiacylglycerol (MGDG) and digalactosyldiacylglycerol (DGDG) being the main lipid types affected (PubMed:22028775). Abnormally large chloroplasts (PubMed:22028775). The double mutant arc6 cjd1 exhibits both phenotypes of single mutants cjd1 and arc6 including altered fatty acid profiles and heterogeneous chloroplasts sizes and shapes, respectively (PubMed:22028775)"}],"commentType":"DISRUPTION PHENOTYPE"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous gene model prediction","sequence":"AAF99779.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Transit peptide","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":58,"modifier":"EXACT"}},"description":"Chloroplast","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Chain","location":{"start":{"value":59,"modifier":"EXACT"},"end":{"value":294,"modifier":"EXACT"}},"description":"Protein CHLOROPLAST J-LIKE DOMAIN 1, chloroplastic","featureId":"PRO_0000454659"},{"type":"Topological domain","location":{"start":{"value":59,"modifier":"EXACT"},"end":{"value":164,"modifier":"EXACT"}},"description":"Stromal","evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"22028775"}]},{"type":"Transmembrane","location":{"start":{"value":165,"modifier":"EXACT"},"end":{"value":182,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":183,"modifier":"EXACT"},"end":{"value":233,"modifier":"EXACT"}},"description":"Chloroplast intermembrane","evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"22028775"}]},{"type":"Transmembrane","location":{"start":{"value":234,"modifier":"EXACT"},"end":{"value":256,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":257,"modifier":"EXACT"},"end":{"value":275,"modifier":"EXACT"}},"description":"Stromal","evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"22028775"}]},{"type":"Transmembrane","location":{"start":{"value":276,"modifier":"EXACT"},"end":{"value":293,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":294,"modifier":"EXACT"},"end":{"value":294,"modifier":"EXACT"}},"description":"Chloroplast intermembrane","evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"22028775"}]},{"type":"Region","location":{"start":{"value":74,"modifier":"EXACT"},"end":{"value":152,"modifier":"EXACT"}},"description":"J-like domain","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"22028775"}]},{"type":"Sequence conflict","location":{"start":{"value":85,"modifier":"EXACT"},"end":{"value":85,"modifier":"EXACT"}},"description":"in Ref. 5; AAM65006","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"E","alternativeSequences":["K"]}},{"type":"Sequence conflict","location":{"start":{"value":285,"modifier":"EXACT"},"end":{"value":285,"modifier":"EXACT"}},"description":"in Ref. 4; AAN31811","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"M","alternativeSequences":["I"]}}],"keywords":[{"id":"KW-0150","category":"Cellular component","name":"Chloroplast"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-0934","category":"Cellular component","name":"Plastid"},{"id":"KW-1001","category":"Cellular component","name":"Plastid inner membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0809","category":"Domain","name":"Transit peptide"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"11130712","citationType":"journal article","authors":["Theologis A.","Ecker J.R.","Palm C.J.","Federspiel N.A.","Kaul S.","White O.","Alonso J.","Altafi H.","Araujo R.","Bowman C.L.","Brooks S.Y.","Buehler E.","Chan A.","Chao Q.","Chen H.","Cheuk R.F.","Chin C.W.","Chung M.K.","Conn L.","Conway A.B.","Conway A.R.","Creasy T.H.","Dewar K.","Dunn P.","Etgu P.","Feldblyum T.V.","Feng J.-D.","Fong B.","Fujii C.Y.","Gill J.E.","Goldsmith A.D.","Haas B.","Hansen N.F.","Hughes B.","Huizar L.","Hunter J.L.","Jenkins J.","Johnson-Hopson C.","Khan S.","Khaykin E.","Kim C.J.","Koo H.L.","Kremenetskaia I.","Kurtz D.B.","Kwan A.","Lam B.","Langin-Hooper S.","Lee A.","Lee J.M.","Lenz C.A.","Li J.H.","Li Y.-P.","Lin X.","Liu S.X.","Liu Z.A.","Luros J.S.","Maiti R.","Marziali A.","Militscher J.","Miranda M.","Nguyen M.","Nierman W.C.","Osborne B.I.","Pai G.","Peterson J.","Pham P.K.","Rizzo M.","Rooney T.","Rowley D.","Sakano H.","Salzberg S.L.","Schwartz J.R.","Shinn P.","Southwick A.M.","Sun H.","Tallon L.J.","Tambunga G.","Toriumi M.J.","Town C.D.","Utterback T.","Van Aken S.","Vaysberg M.","Vysotskaia V.S.","Walker M.","Wu D.","Yu G.","Fraser C.M.","Venter J.C.","Davis R.W."],"citationCrossReferences":[{"database":"PubMed","id":"11130712"},{"database":"DOI","id":"10.1038/35048500"}],"title":"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.","publicationDate":"2000","journal":"Nature","firstPage":"816","lastPage":"820","volume":"408"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"27862469","citationType":"journal article","authors":["Cheng C.Y.","Krishnakumar V.","Chan A.P.","Thibaud-Nissen F.","Schobel S.","Town C.D."],"citationCrossReferences":[{"database":"PubMed","id":"27862469"},{"database":"DOI","id":"10.1111/tpj.13415"}],"title":"Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.","publicationDate":"2017","journal":"Plant J.","firstPage":"789","lastPage":"804","volume":"89"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"CI-CI4AM1G71UC0S","citationType":"submission","authoringGroup":["The Arabidopsis Information Resource (TAIR)"],"title":"Community-consensus reference genome of Arabidopsis thaliana Col-0.","publicationDate":"FEB-2026","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"14593172","citationType":"journal article","authors":["Yamada K.","Lim J.","Dale J.M.","Chen H.","Shinn P.","Palm C.J.","Southwick A.M.","Wu H.C.","Kim C.J.","Nguyen M.","Pham P.K.","Cheuk R.F.","Karlin-Newmann G.","Liu S.X.","Lam B.","Sakano H.","Wu T.","Yu G.","Miranda M.","Quach H.L.","Tripp M.","Chang C.H.","Lee J.M.","Toriumi M.J.","Chan M.M.","Tang C.C.","Onodera C.S.","Deng J.M.","Akiyama K.","Ansari Y.","Arakawa T.","Banh J.","Banno F.","Bowser L.","Brooks S.Y.","Carninci P.","Chao Q.","Choy N.","Enju A.","Goldsmith A.D.","Gurjal M.","Hansen N.F.","Hayashizaki Y.","Johnson-Hopson C.","Hsuan V.W.","Iida K.","Karnes M.","Khan S.","Koesema E.","Ishida J.","Jiang P.X.","Jones T.","Kawai J.","Kamiya A.","Meyers C.","Nakajima M.","Narusaka M.","Seki M.","Sakurai T.","Satou M.","Tamse R.","Vaysberg M.","Wallender E.K.","Wong C.","Yamamura Y.","Yuan S.","Shinozaki K.","Davis R.W.","Theologis A.","Ecker J.R."],"citationCrossReferences":[{"database":"PubMed","id":"14593172"},{"database":"DOI","id":"10.1126/science.1088305"}],"title":"Empirical analysis of transcriptional activity in the Arabidopsis genome.","publicationDate":"2003","journal":"Science","firstPage":"842","lastPage":"846","volume":"302"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"CI-3TH3AFLAVIRO9","citationType":"submission","authors":["Brover V.V.","Troukhan M.E.","Alexandrov N.A.","Lu Y.-P.","Flavell R.B.","Feldmann K.A."],"title":"Full-length cDNA from Arabidopsis thaliana.","publicationDate":"MAR-2002","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"]},{"referenceNumber":6,"citation":{"id":"19376835","citationType":"journal article","authors":["Reiland S.","Messerli G.","Baerenfaller K.","Gerrits B.","Endler A.","Grossmann J.","Gruissem W.","Baginsky S."],"citationCrossReferences":[{"database":"PubMed","id":"19376835"},{"database":"DOI","id":"10.1104/pp.109.138677"}],"title":"Large-scale Arabidopsis phosphoproteome profiling reveals novel chloroplast kinase substrates and phosphorylation networks.","publicationDate":"2009","journal":"Plant Physiol.","firstPage":"889","lastPage":"903","volume":"150"},"referencePositions":["IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":7,"citation":{"id":"22028775","citationType":"journal article","authors":["Ajjawi I.","Coku A.","Froehlich J.E.","Yang Y.","Osteryoung K.W.","Benning C.","Last R.L."],"citationCrossReferences":[{"database":"PubMed","id":"22028775"},{"database":"DOI","id":"10.1371/journal.pone.0025368"}],"title":"A J-like protein influences fatty acid composition of chloroplast lipids in Arabidopsis.","publicationDate":"2011","journal":"PLoS ONE","firstPage":"e25368","lastPage":"e25368","volume":"6"},"referencePositions":["FUNCTION","DISRUPTION PHENOTYPE","INTERACTION WITH ARC6","SUBCELLULAR LOCATION","TOPOLOGY"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AC003981","properties":[{"key":"ProteinId","value":"AAF99779.1"},{"key":"Status","value":"ALT_SEQ"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002684","properties":[{"key":"ProteinId","value":"AEE28325.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"OZ408683","properties":[{"key":"ProteinId","value":"CAO7026603.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AF370182","properties":[{"key":"ProteinId","value":"AAK43997.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AY059140","properties":[{"key":"ProteinId","value":"AAL15246.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"BT000664","properties":[{"key":"ProteinId","value":"AAN31811.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AY087461","properties":[{"key":"ProteinId","value":"AAM65006.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"PIR","id":"H86218","properties":[{"key":"EntryName","value":"H86218"}]},{"database":"PIR","id":"T00717","properties":[{"key":"EntryName","value":"T00717"}]},{"database":"RefSeq","id":"NP_563823.1","properties":[{"key":"NucleotideSequenceId","value":"NM_100737.4"}]},{"database":"AlphaFoldDB","id":"Q93WG3","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q93WG3","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"Q93WG3","properties":[{"key":"Number of interactors","value":"1277"}]},{"database":"STRING","id":"3702.Q93WG3","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"Q93WG3","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"3702-Q93WG3","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"187626","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"837386","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ath:AT1G08640","properties":[{"key":"Description","value":"-"}]},{"database":"Araport","id":"AT1G08640","properties":[{"key":"Description","value":"-"}]},{"database":"TAIR","id":"AT1G08640","properties":[{"key":"GeneName","value":"CJD1"}]},{"database":"eggNOG","id":"ENOG502QQTX","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_079739_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q93WG3","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"HCPKPRI","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"PhylomeDB","id":"Q93WG3","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:Q93WG3","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000006548","properties":[{"key":"Component","value":"Chromosome 1"}]},{"database":"ExpressionAtlas","id":"Q93WG3","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0009507","properties":[{"key":"GoTerm","value":"C:chloroplast"},{"key":"GoEvidenceType","value":"HDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"18431481"}]},{"database":"GO","id":"GO:0009941","properties":[{"key":"GoTerm","value":"C:chloroplast envelope"},{"key":"GoEvidenceType","value":"HDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"12938931"},{"evidenceCode":"ECO:0007005","source":"PubMed","id":"20061580"}]},{"database":"GO","id":"GO:0009706","properties":[{"key":"GoTerm","value":"C:chloroplast inner membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0031969","properties":[{"key":"GoTerm","value":"C:chloroplast membrane"},{"key":"GoEvidenceType","value":"IDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"22028775"}]},{"database":"GO","id":"GO:0005576","properties":[{"key":"GoTerm","value":"C:extracellular region"},{"key":"GoEvidenceType","value":"HDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"28887381"}]},{"database":"GO","id":"GO:0006631","properties":[{"key":"GoTerm","value":"P:fatty acid metabolic process"},{"key":"GoEvidenceType","value":"IMP:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"22028775"}]},{"database":"InterPro","id":"IPR021788","properties":[{"key":"EntryName","value":"CPP1-like"}]},{"database":"PANTHER","id":"PTHR33372","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33372:SF5","properties":[{"key":"EntryName","value":"PROTEIN CHLOROPLAST J-LIKE DOMAIN 1, CHLOROPLASTIC"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF11833","properties":[{"key":"EntryName","value":"CPP1-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAPALSTSCSSVMAFSTSNALRYHHPQISLRNSLRAPKSPSFVRLPLGKVLQSRIVIRAASSAAGNPQSDADFNPYEVLGVNPIEGFDKIKQTYGRKLKDAQRSGDEATAALLEKAYDKLMYAQLMNRKKGVTFGSFKVSKDIKYADKQPIIPWGPRFSRSSKNDMLINLAISVVFSAWIAIKRNVEYKPLQFMSFVFVYRIFEKLKSFEAPSSPIYNEEGEESGRGLRMGKRLLRSLSLVFGSILLASLAYTGFLNGIEYMGYSIPMVLYNNQELIVTASSAFMLYVIASFYR","length":294,"molWeight":32902,"crc64":"23229ABC25AC10D6","md5":"8C4E77B434228E3C30F85288DC9524D7"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"DISRUPTION PHENOTYPE":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Transit peptide":1,"Chain":1,"Topological domain":4,"Transmembrane":3,"Region":1,"Sequence conflict":2},"uniParcId":"UPI00000A82AD"}}