{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q91Z49","secondaryAccessions":["Q3TJ68","Q3UT89","Q8BVM8","Q8K361","Q921B0","Q9D6A8"],"uniProtkbId":"UIF_MOUSE","entryAudit":{"firstPublicDate":"2007-05-15","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2001-12-01","entryVersion":150,"sequenceVersion":1},"annotationScore":4.0,"organism":{"scientificName":"Mus musculus","commonName":"Mouse","taxonId":10090,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Glires","Rodentia","Myomorpha","Muroidea","Muridae","Murinae","Mus","Mus"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"UAP56-interacting factor"}},"alternativeNames":[{"fullName":{"value":"Forty-two-three domain-containing protein 1"},"shortNames":[{"value":"Protein 40-2-3"}]}]},"genes":[{"geneName":{"value":"Fyttd1"},"synonyms":[{"value":"Uif"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4 (By similarity)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22872859"}],"value":"Interacts with DDX39B/UAP56 and NXF1; interaction with DDX39B/UAP56 and NXF1 are mutually exclusive. Interacts with SSRP1; required for its recruitment to mRNAs (By similarity). Interacts with CHTOP"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Nucleus, nucleoplasm","id":"SL-0190"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Nucleus speckle","id":"SL-0186"}}]},{"commentType":"ALTERNATIVE PRODUCTS","events":["Alternative splicing"],"isoforms":[{"name":{"value":"1"},"isoformIds":["Q91Z49-1"],"isoformSequenceStatus":"Displayed"},{"name":{"value":"2"},"isoformIds":["Q91Z49-2"],"sequenceIds":["VSP_025463","VSP_025464"],"isoformSequenceStatus":"Described"},{"name":{"value":"3"},"isoformIds":["Q91Z49-3"],"sequenceIds":["VSP_025462"],"isoformSequenceStatus":"Described"}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the UIF family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":317,"modifier":"EXACT"}},"description":"UAP56-interacting factor","featureId":"PRO_0000287442"},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":26,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Motif","location":{"start":{"value":26,"modifier":"EXACT"},"end":{"value":44,"modifier":"EXACT"}},"description":"UAP56-binding motif"},{"type":"Modified residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"N-acetylmethionine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q96QD9"}]},{"type":"Modified residue","location":{"start":{"value":14,"modifier":"EXACT"},"end":{"value":14,"modifier":"EXACT"}},"description":"Phosphothreonine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"21183079"}]},{"type":"Modified residue","location":{"start":{"value":23,"modifier":"EXACT"},"end":{"value":23,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"17242355"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"21183079"}]},{"type":"Modified residue","location":{"start":{"value":60,"modifier":"EXACT"},"end":{"value":60,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q96QD9"}]},{"type":"Modified residue","location":{"start":{"value":117,"modifier":"EXACT"},"end":{"value":117,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q96QD9"}]},{"type":"Cross-link","location":{"start":{"value":139,"modifier":"EXACT"},"end":{"value":139,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q96QD9"}]},{"type":"Cross-link","location":{"start":{"value":260,"modifier":"EXACT"},"end":{"value":260,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q96QD9"}]},{"type":"Alternative sequence","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":118,"modifier":"EXACT"}},"description":"in isoform 3","evidences":[{"evidenceCode":"ECO:0000305"}],"featureId":"VSP_025462","alternativeSequence":{}},{"type":"Alternative sequence","location":{"start":{"value":166,"modifier":"EXACT"},"end":{"value":174,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"16141072"}],"featureId":"VSP_025463","alternativeSequence":{}},{"type":"Alternative sequence","location":{"start":{"value":219,"modifier":"EXACT"},"end":{"value":243,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"16141072"}],"featureId":"VSP_025464","alternativeSequence":{}},{"type":"Sequence conflict","location":{"start":{"value":73,"modifier":"EXACT"},"end":{"value":73,"modifier":"EXACT"}},"description":"in Ref. 3; CAC51437","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"I","alternativeSequences":["V"]}},{"type":"Sequence conflict","location":{"start":{"value":84,"modifier":"EXACT"},"end":{"value":84,"modifier":"EXACT"}},"description":"in Ref. 2; AAH28253","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"L","alternativeSequences":["V"]}},{"type":"Sequence conflict","location":{"start":{"value":307,"modifier":"EXACT"},"end":{"value":307,"modifier":"EXACT"}},"description":"in Ref. 3; CAC51437","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"S","alternativeSequences":["C"]}},{"type":"Sequence conflict","location":{"start":{"value":314,"modifier":"EXACT"},"end":{"value":314,"modifier":"EXACT"}},"description":"in Ref. 1; BAB29357","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"V","alternativeSequences":["G"]}}],"keywords":[{"id":"KW-0007","category":"PTM","name":"Acetylation"},{"id":"KW-0025","category":"Coding sequence diversity","name":"Alternative splicing"},{"id":"KW-1017","category":"PTM","name":"Isopeptide bond"},{"id":"KW-0509","category":"Biological process","name":"mRNA transport"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0694","category":"Molecular function","name":"RNA-binding"},{"id":"KW-0813","category":"Biological process","name":"Transport"},{"id":"KW-0832","category":"PTM","name":"Ubl conjugation"}],"references":[{"referenceNumber":1,"citation":{"id":"16141072","citationType":"journal article","authors":["Carninci P.","Kasukawa T.","Katayama S.","Gough J.","Frith M.C.","Maeda N.","Oyama R.","Ravasi T.","Lenhard B.","Wells C.","Kodzius R.","Shimokawa K.","Bajic V.B.","Brenner S.E.","Batalov S.","Forrest A.R.","Zavolan M.","Davis M.J.","Wilming L.G.","Aidinis V.","Allen J.E.","Ambesi-Impiombato A.","Apweiler R.","Aturaliya R.N.","Bailey T.L.","Bansal M.","Baxter L.","Beisel K.W.","Bersano T.","Bono H.","Chalk A.M.","Chiu K.P.","Choudhary V.","Christoffels A.","Clutterbuck D.R.","Crowe M.L.","Dalla E.","Dalrymple B.P.","de Bono B.","Della Gatta G.","di Bernardo D.","Down T.","Engstrom P.","Fagiolini M.","Faulkner G.","Fletcher C.F.","Fukushima T.","Furuno M.","Futaki S.","Gariboldi M.","Georgii-Hemming P.","Gingeras T.R.","Gojobori T.","Green R.E.","Gustincich S.","Harbers M.","Hayashi Y.","Hensch T.K.","Hirokawa N.","Hill D.","Huminiecki L.","Iacono M.","Ikeo K.","Iwama A.","Ishikawa T.","Jakt M.","Kanapin A.","Katoh M.","Kawasawa Y.","Kelso J.","Kitamura H.","Kitano H.","Kollias G.","Krishnan S.P.","Kruger A.","Kummerfeld S.K.","Kurochkin I.V.","Lareau L.F.","Lazarevic D.","Lipovich L.","Liu J.","Liuni S.","McWilliam S.","Madan Babu M.","Madera M.","Marchionni L.","Matsuda H.","Matsuzawa S.","Miki H.","Mignone F.","Miyake S.","Morris K.","Mottagui-Tabar S.","Mulder N.","Nakano N.","Nakauchi H.","Ng P.","Nilsson R.","Nishiguchi S.","Nishikawa S.","Nori F.","Ohara O.","Okazaki Y.","Orlando V.","Pang K.C.","Pavan W.J.","Pavesi G.","Pesole G.","Petrovsky N.","Piazza S.","Reed J.","Reid J.F.","Ring B.Z.","Ringwald M.","Rost B.","Ruan Y.","Salzberg S.L.","Sandelin A.","Schneider C.","Schoenbach C.","Sekiguchi K.","Semple C.A.","Seno S.","Sessa L.","Sheng Y.","Shibata Y.","Shimada H.","Shimada K.","Silva D.","Sinclair B.","Sperling S.","Stupka E.","Sugiura K.","Sultana R.","Takenaka Y.","Taki K.","Tammoja K.","Tan S.L.","Tang S.","Taylor M.S.","Tegner J.","Teichmann S.A.","Ueda H.R.","van Nimwegen E.","Verardo R.","Wei C.L.","Yagi K.","Yamanishi H.","Zabarovsky E.","Zhu S.","Zimmer A.","Hide W.","Bult C.","Grimmond S.M.","Teasdale R.D.","Liu E.T.","Brusic V.","Quackenbush J.","Wahlestedt C.","Mattick J.S.","Hume D.A.","Kai C.","Sasaki D.","Tomaru Y.","Fukuda S.","Kanamori-Katayama M.","Suzuki M.","Aoki J.","Arakawa T.","Iida J.","Imamura K.","Itoh M.","Kato T.","Kawaji H.","Kawagashira N.","Kawashima T.","Kojima M.","Kondo S.","Konno H.","Nakano K.","Ninomiya N.","Nishio T.","Okada M.","Plessy C.","Shibata K.","Shiraki T.","Suzuki S.","Tagami M.","Waki K.","Watahiki A.","Okamura-Oho Y.","Suzuki H.","Kawai J.","Hayashizaki Y."],"citationCrossReferences":[{"database":"PubMed","id":"16141072"},{"database":"DOI","id":"10.1126/science.1112014"}],"title":"The transcriptional landscape of the mammalian genome.","publicationDate":"2005","journal":"Science","firstPage":"1559","lastPage":"1563","volume":"309"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)"],"referenceComments":[{"value":"C57BL/6J","type":"STRAIN"},{"value":"NOD","type":"STRAIN"},{"value":"Egg","type":"TISSUE"},{"value":"Liver","type":"TISSUE"},{"value":"Lung","type":"TISSUE"},{"value":"Pancreas","type":"TISSUE"},{"value":"Placenta","type":"TISSUE"},{"value":"Spleen","type":"TISSUE"},{"value":"Testis","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)"],"referenceComments":[{"value":"FVB/N","type":"STRAIN"},{"value":"Mammary tumor","type":"TISSUE"}]},{"referenceNumber":3,"citation":{"id":"CI-A456C6DVFNV4O","citationType":"thesis","authors":["Schmidt T."],"publicationDate":"2001","institute":"Faculty of Biological Sciences / Goettingen","address":"Germany"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA] OF 3-317 (ISOFORM 1)"]},{"referenceNumber":4,"citation":{"id":"17242355","citationType":"journal article","authors":["Villen J.","Beausoleil S.A.","Gerber S.A.","Gygi S.P."],"citationCrossReferences":[{"database":"PubMed","id":"17242355"},{"database":"DOI","id":"10.1073/pnas.0609836104"}],"title":"Large-scale phosphorylation analysis of mouse liver.","publicationDate":"2007","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"1488","lastPage":"1493","volume":"104"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-23","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"],"referenceComments":[{"value":"Liver","type":"TISSUE"}]},{"referenceNumber":5,"citation":{"id":"21183079","citationType":"journal article","authors":["Huttlin E.L.","Jedrychowski M.P.","Elias J.E.","Goswami T.","Rad R.","Beausoleil S.A.","Villen J.","Haas W.","Sowa M.E.","Gygi S.P."],"citationCrossReferences":[{"database":"PubMed","id":"21183079"},{"database":"DOI","id":"10.1016/j.cell.2010.12.001"}],"title":"A tissue-specific atlas of mouse protein phosphorylation and expression.","publicationDate":"2010","journal":"Cell","firstPage":"1174","lastPage":"1189","volume":"143"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-14 AND SER-23","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"],"referenceComments":[{"value":"Brain","type":"TISSUE"},{"value":"Brown adipose tissue","type":"TISSUE"},{"value":"Kidney","type":"TISSUE"},{"value":"Liver","type":"TISSUE"},{"value":"Testis","type":"TISSUE"}]},{"referenceNumber":6,"citation":{"id":"22872859","citationType":"journal article","authors":["Fanis P.","Gillemans N.","Aghajanirefah A.","Pourfarzad F.","Demmers J.","Esteghamat F.","Vadlamudi R.K.","Grosveld F.","Philipsen S.","van Dijk T.B."],"citationCrossReferences":[{"database":"PubMed","id":"22872859"},{"database":"DOI","id":"10.1074/mcp.m112.017194"}],"title":"Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.","publicationDate":"2012","journal":"Mol. Cell. Proteomics","firstPage":"1263","lastPage":"1273","volume":"11"},"referencePositions":["INTERACTION WITH CHTOP"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AK014447","properties":[{"key":"ProteinId","value":"BAB29357.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK029785","properties":[{"key":"ProteinId","value":"BAC26615.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK050448","properties":[{"key":"ProteinId","value":"BAC34260.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK050479","properties":[{"key":"ProteinId","value":"BAC34279.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK077184","properties":[{"key":"ProteinId","value":"BAC36666.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK139638","properties":[{"key":"ProteinId","value":"BAE24091.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK157602","properties":[{"key":"ProteinId","value":"BAE34132.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK161252","properties":[{"key":"ProteinId","value":"BAE36271.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK166032","properties":[{"key":"ProteinId","value":"BAE38533.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK167564","properties":[{"key":"ProteinId","value":"BAE39627.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK170511","properties":[{"key":"ProteinId","value":"BAE41848.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"BC010204","properties":[{"key":"ProteinId","value":"AAH10204.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"BC028253","properties":[{"key":"ProteinId","value":"AAH28253.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AJ344096","properties":[{"key":"ProteinId","value":"CAC51437.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS28125.1","properties":[{"key":"Description","value":"-"}],"isoformId":"Q91Z49-1"},{"database":"CCDS","id":"CCDS49833.1","properties":[{"key":"Description","value":"-"}],"isoformId":"Q91Z49-2"},{"database":"RefSeq","id":"NP_001152821.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001159349.1"}],"isoformId":"Q91Z49-2"},{"database":"RefSeq","id":"NP_081502.2","properties":[{"key":"NucleotideSequenceId","value":"NM_027226.4"}],"isoformId":"Q91Z49-1"},{"database":"AlphaFoldDB","id":"Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"213703","properties":[{"key":"Interactions","value":"6"}]},{"database":"FunCoup","id":"Q91Z49","properties":[{"key":"Number of interactors","value":"2584"}]},{"database":"IntAct","id":"Q91Z49","properties":[{"key":"Interactions","value":"1"}]},{"database":"STRING","id":"10090.ENSMUSP00000023489","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"Q91Z49","properties":[{"key":"glycosylation","value":"4 sites, 2 N-linked glycans (2 sites)"}]},{"database":"iPTMnet","id":"Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"SwissPalm","id":"Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"10090-ENSMUSP00000023489","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"298430","properties":[{"key":"Description","value":"-"}],"isoformId":"Q91Z49-1"},{"database":"ProteomicsDB","id":"298431","properties":[{"key":"Description","value":"-"}],"isoformId":"Q91Z49-2"},{"database":"ProteomicsDB","id":"298432","properties":[{"key":"Description","value":"-"}],"isoformId":"Q91Z49-3"},{"database":"Pumba","id":"Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"54015","properties":[{"key":"antibodies","value":"141 antibodies from 22 providers"}]},{"database":"DNASU","id":"69823","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENSMUST00000023489.11","properties":[{"key":"ProteinId","value":"ENSMUSP00000023489.5"},{"key":"GeneId","value":"ENSMUSG00000022800.15"}],"isoformId":"Q91Z49-1"},{"database":"Ensembl","id":"ENSMUST00000171325.9","properties":[{"key":"ProteinId","value":"ENSMUSP00000131446.2"},{"key":"GeneId","value":"ENSMUSG00000022800.15"}],"isoformId":"Q91Z49-2"},{"database":"Ensembl","id":"ENSMUST00000232272.2","properties":[{"key":"ProteinId","value":"ENSMUSP00000155929.2"},{"key":"GeneId","value":"ENSMUSG00000022800.15"}],"isoformId":"Q91Z49-3"},{"database":"GeneID","id":"69823","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"mmu:69823","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"uc007yzp.2","properties":[{"key":"OrganismName","value":"mouse"}],"isoformId":"Q91Z49-1"},{"database":"UCSC","id":"uc007yzq.2","properties":[{"key":"OrganismName","value":"mouse"}],"isoformId":"Q91Z49-2"},{"database":"AGR","id":"MGI:1917955","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"84248","properties":[{"key":"Description","value":"-"}]},{"database":"MGI","id":"MGI:1917955","properties":[{"key":"GeneName","value":"Fyttd1"}]},{"database":"VEuPathDB","id":"HostDB:ENSMUSG00000022800","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502QWD4","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00390000012807","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_076911_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"NGTRQFR","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"9938627at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"Reactome","id":"R-MMU-159236","properties":[{"key":"PathwayName","value":"Transport of Mature mRNA derived from an Intron-Containing Transcript"}]},{"database":"Reactome","id":"R-MMU-72187","properties":[{"key":"PathwayName","value":"mRNA 3'-end processing"}]},{"database":"BioGRID-ORCS","id":"69823","properties":[{"key":"hits","value":"1 hit in 76 CRISPR screens"}]},{"database":"PRO","id":"PR:Q91Z49","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000589","properties":[{"key":"Component","value":"Chromosome 16"}]},{"database":"RNAct","id":"Q91Z49","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSMUSG00000022800","properties":[{"key":"ExpressionPatterns","value":"Expressed in spermatocyte and 273 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"Q91Z49","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"ISO:GO_Central"}]},{"database":"GO","id":"GO:0016607","properties":[{"key":"GoTerm","value":"C:nuclear speck"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0005730","properties":[{"key":"GoTerm","value":"C:nucleolus"},{"key":"GoEvidenceType","value":"ISO:GO_Central"}]},{"database":"GO","id":"GO:0005654","properties":[{"key":"GoTerm","value":"C:nucleoplasm"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0003729","properties":[{"key":"GoTerm","value":"F:mRNA binding"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0006406","properties":[{"key":"GoTerm","value":"P:mRNA export from nucleus"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"InterPro","id":"IPR009782","properties":[{"key":"EntryName","value":"FYTTD1"}]},{"database":"PANTHER","id":"PTHR21038","properties":[{"key":"EntryName","value":"40-2-3 PROTEIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR21038:SF2","properties":[{"key":"EntryName","value":"UAP56-INTERACTING FACTOR"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07078","properties":[{"key":"EntryName","value":"FYTT"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MNRFGTRLVGATATPPPPPKARSNENLDKIDMSLDDIIKLNRKEGKKQNFPRLNRRLQQSGTRQFRMRVRWGIQQNSGFGKTSLSRRGRVLPGKRRPYGVITGLAARKATGIRKGISPMNRPPLSDKNIERYFPALKRKTSLLRQNEVQRKQVAVLKRPNQLNRKNNIPANFTRNGNKLSHQKDTRQATFLFRRGLKVQTQLNTEQLIDDVVAKRTRQWRTSTTNGGILTVSIDNPGAVQCPVTQKPRLTRTAVPSFLTKREQSDVKKVPKGVPLQFDINSVGKQTGMTLNERFGILKEQRANLTFSKGGSRFVTVG","length":317,"molWeight":35887,"crc64":"03182120505F4F83","md5":"7D08DF24E02D0BB9DD5FE00DB80314AE"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"ALTERNATIVE PRODUCTS":3,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Region":1,"Motif":1,"Modified residue":5,"Cross-link":2,"Alternative sequence":3,"Sequence conflict":4},"uniParcId":"UPI0000021FF7"}}