{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q8XCP5","uniProtkbId":"YOBD_ECO57","entryAudit":{"firstPublicDate":"2003-07-19","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2002-03-01","entryVersion":111,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Escherichia coli O157:H7","taxonId":83334,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"UPF0266 membrane protein YobD"}}},"genes":[{"geneName":{"value":"yobD"},"orderedLocusNames":[{"value":"Z2863"},{"value":"ECs2530"}]}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Cell inner membrane","id":"SL-0037"},"topology":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the UPF0266 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":152,"modifier":"EXACT"}},"description":"UPF0266 membrane protein YobD","featureId":"PRO_0000218114"},{"type":"Topological domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":5,"modifier":"EXACT"}},"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":6,"modifier":"EXACT"},"end":{"value":26,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":27,"modifier":"EXACT"},"end":{"value":44,"modifier":"EXACT"}},"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":45,"modifier":"EXACT"},"end":{"value":65,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":66,"modifier":"EXACT"},"end":{"value":66,"modifier":"EXACT"}},"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":67,"modifier":"EXACT"},"end":{"value":87,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":88,"modifier":"EXACT"},"end":{"value":152,"modifier":"EXACT"}},"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}],"keywords":[{"id":"KW-0997","category":"Cellular component","name":"Cell inner membrane"},{"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"11206551","citationType":"journal article","authors":["Perna N.T.","Plunkett G. III","Burland V.","Mau B.","Glasner J.D.","Rose D.J.","Mayhew G.F.","Evans P.S.","Gregor J.","Kirkpatrick H.A.","Posfai G.","Hackett J.","Klink S.","Boutin A.","Shao Y.","Miller L.","Grotbeck E.J.","Davis N.W.","Lim A.","Dimalanta E.T.","Potamousis K.","Apodaca J.","Anantharaman T.S.","Lin J.","Yen G.","Schwartz D.C.","Welch R.A.","Blattner F.R."],"citationCrossReferences":[{"database":"PubMed","id":"11206551"},{"database":"DOI","id":"10.1038/35054089"}],"title":"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.","publicationDate":"2001","journal":"Nature","firstPage":"529","lastPage":"533","volume":"409"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"O157:H7 / EDL933 / ATCC 700927 / EHEC","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"11258796","citationType":"journal article","authors":["Hayashi T.","Makino K.","Ohnishi M.","Kurokawa K.","Ishii K.","Yokoyama K.","Han C.-G.","Ohtsubo E.","Nakayama K.","Murata T.","Tanaka M.","Tobe T.","Iida T.","Takami H.","Honda T.","Sasakawa C.","Ogasawara N.","Yasunaga T.","Kuhara S.","Shiba T.","Hattori M.","Shinagawa H."],"citationCrossReferences":[{"database":"PubMed","id":"11258796"},{"database":"DOI","id":"10.1093/dnares/8.1.11"}],"title":"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.","publicationDate":"2001","journal":"DNA Res.","firstPage":"11","lastPage":"22","volume":"8"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"O157:H7 / Sakai / RIMD 0509952 / EHEC","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AE005174","properties":[{"key":"ProteinId","value":"AAG56809.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BA000007","properties":[{"key":"ProteinId","value":"BAB35953.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"B99945","properties":[{"key":"EntryName","value":"B99945"}]},{"database":"PIR","id":"E85793","properties":[{"key":"EntryName","value":"E85793"}]},{"database":"RefSeq","id":"NP_310557.1","properties":[{"key":"NucleotideSequenceId","value":"NC_002695.2"}]},{"database":"RefSeq","id":"WP_000156258.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_AP018488.1"}]},{"database":"AlphaFoldDB","id":"Q8XCP5","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"155864.Z2863","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"75171889","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"912870","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ece:Z2863","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecs:ECs_2530","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|386585.9.peg.2651","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"eggNOG","id":"COG4811","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"HOGENOM","id":"CLU_133645_0_0_6","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"LYLFWIR","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"Proteomes","id":"UP000000558","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"HAMAP","id":"MF_01071","properties":[{"key":"EntryName","value":"UPF0266"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR009328","properties":[{"key":"EntryName","value":"DUF986"}]},{"database":"NCBIfam","id":"NF002791","properties":[{"key":"EntryName","value":"PRK02913.1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF06173","properties":[{"key":"EntryName","value":"DUF986"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF020687","properties":[{"key":"EntryName","value":"UCP020687"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGRIDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFANVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLERIYKLLVSTQ","length":152,"molWeight":17643,"crc64":"06C3EEB44BC8BE19","md5":"A919BD23DEF66C12E7D298292109CD51"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Topological domain":4,"Transmembrane":3},"uniParcId":"UPI00000D0452"}}