{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q8WVP5","secondaryAccessions":["D6W627"],"uniProtkbId":"TP8L1_HUMAN","entryAudit":{"firstPublicDate":"2007-05-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2007-05-01","entryVersion":146,"sequenceVersion":2},"annotationScore":5.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Tumor necrosis factor alpha-induced protein 8-like protein 1"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8K288"}],"value":"TIPE1"},{"value":"TNF alpha-induced protein 8-like protein 1"},{"value":"TNFAIP8-like protein 1"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"24444419"}],"value":"Oxidative stress-regulated gene-beta"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"24444419"}],"value":"Oxy-beta"}]}]},"genes":[{"geneName":{"value":"TNFAIP8L1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8K288"}],"value":"Acts as a negative regulator of mTOR activity"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8K288"}],"value":"Interacts with FBXW5; TNFAIP8L1 competes with TSC2 to bind FBXW5 increasing TSC2 stability by preventing its ubiquitination"}],"commentType":"SUBUNIT"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"Q8N2N9-4","geneName":"ANKRD36B","intActId":"EBI-12170453"},"numberOfExperiments":5,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"Q6NZI2","geneName":"CAVIN1","intActId":"EBI-2559016"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"Q92997","geneName":"DVL3","intActId":"EBI-739789"},"numberOfExperiments":6,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"O60447","geneName":"EVI5","intActId":"EBI-852291"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"Q92876","geneName":"KLK6","intActId":"EBI-2432309"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"Q9NPJ6","geneName":"MED4","intActId":"EBI-394607"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"Q9H8W4","geneName":"PLEKHF2","intActId":"EBI-742388"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"P61289","geneName":"PSME3","intActId":"EBI-355546"},"numberOfExperiments":6,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"P32969","geneName":"RPL9P9","intActId":"EBI-358122"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"P09012","geneName":"SNRPA","intActId":"EBI-607085"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"Q96MF2","geneName":"STAC3","intActId":"EBI-745680"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"Q8WVP5","geneName":"TNFAIP8L1","intActId":"EBI-752102"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8WVP5","intActId":"EBI-752102"},"interactantTwo":{"uniProtKBAccession":"Q15696","geneName":"ZRSR2","intActId":"EBI-6657923"},"numberOfExperiments":3,"organismDiffer":false}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q8K288"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"21600655"}],"value":"High expression detected in most carcinoma cell lines, especially in cells transformed with virus genomes"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"24444419"}],"value":"Up-regulated by oxidative stress (OS) at both transcriptional and translational levels"}],"commentType":"INDUCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the TNFAIP8 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":186,"modifier":"EXACT"}},"description":"Tumor necrosis factor alpha-induced protein 8-like protein 1","featureId":"PRO_0000285724"},{"type":"Natural variant","location":{"start":{"value":118,"modifier":"EXACT"},"end":{"value":118,"modifier":"EXACT"}},"description":"in dbSNP:rs17851549","featureCrossReferences":[{"database":"dbSNP","id":"rs17851549"}],"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"15489334"}],"featureId":"VAR_032048","alternativeSequence":{"originalSequence":"A","alternativeSequences":["V"]}}],"keywords":[{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"15057824","citationType":"journal article","authors":["Grimwood J.","Gordon L.A.","Olsen A.S.","Terry A.","Schmutz J.","Lamerdin J.E.","Hellsten U.","Goodstein D.","Couronne O.","Tran-Gyamfi M.","Aerts A.","Altherr M.","Ashworth L.","Bajorek E.","Black S.","Branscomb E.","Caenepeel S.","Carrano A.V.","Caoile C.","Chan Y.M.","Christensen M.","Cleland C.A.","Copeland A.","Dalin E.","Dehal P.","Denys M.","Detter J.C.","Escobar J.","Flowers D.","Fotopulos D.","Garcia C.","Georgescu A.M.","Glavina T.","Gomez M.","Gonzales E.","Groza M.","Hammon N.","Hawkins T.","Haydu L.","Ho I.","Huang W.","Israni S.","Jett J.","Kadner K.","Kimball H.","Kobayashi A.","Larionov V.","Leem S.-H.","Lopez F.","Lou Y.","Lowry S.","Malfatti S.","Martinez D.","McCready P.M.","Medina C.","Morgan J.","Nelson K.","Nolan M.","Ovcharenko I.","Pitluck S.","Pollard M.","Popkie A.P.","Predki P.","Quan G.","Ramirez L.","Rash S.","Retterer J.","Rodriguez A.","Rogers S.","Salamov A.","Salazar A.","She X.","Smith D.","Slezak T.","Solovyev V.","Thayer N.","Tice H.","Tsai M.","Ustaszewska A.","Vo N.","Wagner M.","Wheeler J.","Wu K.","Xie G.","Yang J.","Dubchak I.","Furey T.S.","DeJong P.","Dickson M.","Gordon D.","Eichler E.E.","Pennacchio L.A.","Richardson P.","Stubbs L.","Rokhsar D.S.","Myers R.M.","Rubin E.M.","Lucas S.M."],"citationCrossReferences":[{"database":"PubMed","id":"15057824"},{"database":"DOI","id":"10.1038/nature02399"}],"title":"The DNA sequence and biology of human chromosome 19.","publicationDate":"2004","journal":"Nature","firstPage":"529","lastPage":"535","volume":"428"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":2,"citation":{"id":"CI-5GBD0VIIJ7C63","citationType":"submission","authors":["Mural R.J.","Istrail S.","Sutton G.G.","Florea L.","Halpern A.L.","Mobarry C.M.","Lippert R.","Walenz B.","Shatkay H.","Dew I.","Miller J.R.","Flanigan M.J.","Edwards N.J.","Bolanos R.","Fasulo D.","Halldorsson B.V.","Hannenhalli S.","Turner R.","Yooseph S.","Lu F.","Nusskern D.R.","Shue B.C.","Zheng X.H.","Zhong F.","Delcher A.L.","Huson D.H.","Kravitz S.A.","Mouchard L.","Reinert K.","Remington K.A.","Clark A.G.","Waterman M.S.","Eichler E.E.","Adams M.D.","Hunkapiller M.W.","Myers E.W.","Venter J.C."],"publicationDate":"SEP-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":3,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]","VARIANT VAL-118"],"referenceComments":[{"value":"Lung","type":"TISSUE"}]},{"referenceNumber":4,"citation":{"id":"21600655","citationType":"journal article","authors":["Cui J.","Zhang G.","Hao C.","Wang Y.","Lou Y.","Zhang W.","Wang J.","Liu S."],"citationCrossReferences":[{"database":"PubMed","id":"21600655"},{"database":"DOI","id":"10.1016/j.molimm.2011.04.023"}],"title":"The expression of TIPE1 in murine tissues and human cell lines.","publicationDate":"2011","journal":"Mol. Immunol.","firstPage":"1548","lastPage":"1555","volume":"48"},"referencePositions":["TISSUE SPECIFICITY"]},{"referenceNumber":5,"citation":{"id":"24444419","citationType":"journal article","authors":["Ha J.Y.","Kim J.S.","Kang Y.H.","Bok E.","Kim Y.S.","Son J.H."],"citationCrossReferences":[{"database":"PubMed","id":"24444419"},{"database":"DOI","id":"10.1111/jnc.12643"}],"title":"Tnfaip8 l1/Oxi-beta binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.","publicationDate":"2014","journal":"J. Neurochem.","firstPage":"527","lastPage":"538","volume":"129"},"referencePositions":["INDUCTION"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AC005339","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CH471139","properties":[{"key":"ProteinId","value":"EAW69204.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CH471139","properties":[{"key":"ProteinId","value":"EAW69205.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC017672","properties":[{"key":"ProteinId","value":"AAH17672.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS12132.1","properties":[{"key":"Description","value":"-"}]},{"database":"RefSeq","id":"NP_001161414.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001167942.1"}]},{"database":"RefSeq","id":"NP_689575.2","properties":[{"key":"NucleotideSequenceId","value":"NM_152362.3"}]},{"database":"RefSeq","id":"XP_005259544.1","properties":[{"key":"NucleotideSequenceId","value":"XM_005259487.4"}]},{"database":"RefSeq","id":"XP_011525982.1","properties":[{"key":"NucleotideSequenceId","value":"XM_011527680.3"}]},{"database":"RefSeq","id":"XP_054175769.1","properties":[{"key":"NucleotideSequenceId","value":"XM_054319794.1"}]},{"database":"RefSeq","id":"XP_054175770.1","properties":[{"key":"NucleotideSequenceId","value":"XM_054319795.1"}]},{"database":"AlphaFoldDB","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"125973","properties":[{"key":"Interactions","value":"50"}]},{"database":"FunCoup","id":"Q8WVP5","properties":[{"key":"Number of interactors","value":"514"}]},{"database":"IntAct","id":"Q8WVP5","properties":[{"key":"Interactions","value":"12"}]},{"database":"STRING","id":"9606.ENSP00000444215","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"TNFAIP8L1","properties":[{"key":"Description","value":"-"}]},{"database":"DMDM","id":"146325794","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000444215","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"74809","properties":[{"key":"Description","value":"-"}]},{"database":"Pumba","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"23694","properties":[{"key":"antibodies","value":"49 antibodies from 22 providers"}]},{"database":"DNASU","id":"126282","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENST00000327473.9","properties":[{"key":"ProteinId","value":"ENSP00000331827.3"},{"key":"GeneId","value":"ENSG00000185361.10"}]},{"database":"Ensembl","id":"ENST00000536716.1","properties":[{"key":"ProteinId","value":"ENSP00000444215.1"},{"key":"GeneId","value":"ENSG00000185361.10"}]},{"database":"Ensembl","id":"ENST00000883935.1","properties":[{"key":"ProteinId","value":"ENSP00000553994.1"},{"key":"GeneId","value":"ENSG00000185361.10"}]},{"database":"Ensembl","id":"ENST00000883936.1","properties":[{"key":"ProteinId","value":"ENSP00000553995.1"},{"key":"GeneId","value":"ENSG00000185361.10"}]},{"database":"Ensembl","id":"ENST00000883937.1","properties":[{"key":"ProteinId","value":"ENSP00000553996.1"},{"key":"GeneId","value":"ENSG00000185361.10"}]},{"database":"Ensembl","id":"ENST00000961763.1","properties":[{"key":"ProteinId","value":"ENSP00000631822.1"},{"key":"GeneId","value":"ENSG00000185361.10"}]},{"database":"GeneID","id":"126282","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:126282","properties":[{"key":"Description","value":"-"}]},{"database":"MANE-Select","id":"ENST00000327473.9","properties":[{"key":"ProteinId","value":"ENSP00000331827.3"},{"key":"RefSeqNucleotideId","value":"NM_152362.3"},{"key":"RefSeqProteinId","value":"NP_689575.2"}]},{"database":"UCSC","id":"uc002max.4","properties":[{"key":"OrganismName","value":"human"}]},{"database":"AGR","id":"HGNC:28279","properties":[{"key":"Description","value":"-"}]},{"database":"ClinPGx","id":"PA142670722","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"126282","properties":[{"key":"Description","value":"-"}]},{"database":"DisGeNET","id":"126282","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"TNFAIP8L1","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:28279","properties":[{"key":"GeneName","value":"TNFAIP8L1"}]},{"database":"HPA","id":"ENSG00000185361","properties":[{"key":"ExpressionPatterns","value":"Tissue enhanced (intestine, liver)"}]},{"database":"MIM","id":"615869","properties":[{"key":"Type","value":"gene"}]},{"database":"OpenTargets","id":"ENSG00000185361","properties":[{"key":"Description","value":"-"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000185361","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502S00N","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00390000003488","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_085918_1_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"QRICNGL","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"10055976at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"Q8WVP5","properties":[{"key":"Number of GO annotations","value":"2 GO annotations based on evolutionary models"}]},{"database":"PhylomeDB","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"PathwayCommons","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"Reactome","id":"R-HSA-1483255","properties":[{"key":"PathwayName","value":"PI Metabolism"}]},{"database":"SignaLink","id":"Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"Agora","id":"ENSG00000185361","properties":[{"key":"NominatedTarget","value":"-"}]},{"database":"BioGRID-ORCS","id":"126282","properties":[{"key":"hits","value":"17 hits in 1157 CRISPR screens"}]},{"database":"ChiTaRS","id":"TNFAIP8L1","properties":[{"key":"OrganismName","value":"human"}]},{"database":"GenomeRNAi","id":"126282","properties":[{"key":"Description","value":"-"}]},{"database":"Pharos","id":"Q8WVP5","properties":[{"key":"DevelopmentLevel","value":"Tdark"}]},{"database":"PRO","id":"PR:Q8WVP5","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome 19"}]},{"database":"RNAct","id":"Q8WVP5","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000185361","properties":[{"key":"ExpressionPatterns","value":"Expressed in bronchial epithelial cell and 149 other cell types or tissues"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0042802","properties":[{"key":"GoTerm","value":"F:identical protein binding"},{"key":"GoEvidenceType","value":"IPI:IntAct"}],"evidences":[{"evidenceCode":"ECO:0000353","source":"PubMed","id":"32296183"}]},{"database":"GO","id":"GO:0032007","properties":[{"key":"GoTerm","value":"P:negative regulation of TOR signaling"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0042981","properties":[{"key":"GoTerm","value":"P:regulation of apoptotic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"1.20.1440.160:FF:000001","properties":[{"key":"EntryName","value":"Tumor necrosis factor alpha-induced protein 8-like 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.1440.160","properties":[{"key":"EntryName","value":"Tumor necrosis factor alpha-induced protein 8-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR008477","properties":[{"key":"EntryName","value":"TNFAIP8-like"}]},{"database":"InterPro","id":"IPR038355","properties":[{"key":"EntryName","value":"TNFAIP8_sf"}]},{"database":"PANTHER","id":"PTHR12757:SF2","properties":[{"key":"EntryName","value":"TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8-LIKE PROTEIN 1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR12757","properties":[{"key":"EntryName","value":"TUMOR NECROSIS FACTOR INDUCED PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF05527","properties":[{"key":"EntryName","value":"TNFAIP8"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDTFSTKSLALQAQKKLLSKMASKAVVAVLVDDTSSEVLDELYRATREFTRSRKEAQKMLKNLVKVALKLGLLLRGDQLGGEELALLRRFRHRARCLAMTAVSFHQVDFTFDRRVLAAGLLECRDLLHQAVGPHLTAKSHGRINHVFGHLADCDFLAALYGPAEPYRSHLRRICEGLGRMLDEGSL","length":186,"molWeight":20827,"crc64":"352B0E7A2FB6D216","md5":"002EFEF154EEEB4F82B6EB86E7CDA848"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"INTERACTION":13,"SUBCELLULAR LOCATION":1,"TISSUE SPECIFICITY":1,"INDUCTION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Natural variant":1},"uniParcId":"UPI000013EB11"}}