{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q8U3L4","uniProtkbId":"Y452_PYRFU","entryAudit":{"firstPublicDate":"2002-10-25","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"2002-06-01","entryVersion":84,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)","taxonId":186497,"lineage":["Archaea","Methanobacteriati","Methanobacteriota","Thermococci","Thermococcales","Thermococcaceae","Pyrococcus"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00585"}],"value":"UPF0216 protein PF0452"}}},"genes":[{"orderedLocusNames":[{"value":"PF0452"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00585"}],"value":"Belongs to the UPF0216 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":136,"modifier":"EXACT"}},"description":"UPF0216 protein PF0452","featureId":"PRO_0000144228"}],"keywords":[{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"10430560","citationType":"journal article","authors":["Maeder D.L.","Weiss R.B.","Dunn D.M.","Cherry J.L.","Gonzalez J.M.","DiRuggiero J.","Robb F.T."],"citationCrossReferences":[{"database":"PubMed","id":"10430560"},{"database":"DOI","id":"10.1093/genetics/152.4.1299"}],"title":"Divergence of the hyperthermophilic archaea Pyrococcus furiosus and P. horikoshii inferred from complete genomic sequences.","publicationDate":"1999","journal":"Genetics","firstPage":"1299","lastPage":"1305","volume":"152"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 43587 / DSM 3638 / JCM 8422 / Vc1","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AE009950","properties":[{"key":"ProteinId","value":"AAL80576.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_011011569.1","properties":[{"key":"NucleotideSequenceId","value":"NC_003413.1"}]},{"database":"AlphaFoldDB","id":"Q8U3L4","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"186497.PF0452","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"186497-PF0452","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"13302262","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"pfu:PF0452","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|186497.12.peg.476","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"eggNOG","id":"arCOG01921","properties":[{"key":"ToxonomicScope","value":"Archaea"}]},{"database":"HOGENOM","id":"CLU_146474_0_0_2","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"18795at2157","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q8U3L4","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001013","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"HAMAP","id":"MF_00585","properties":[{"key":"EntryName","value":"UPF0216"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR002746","properties":[{"key":"EntryName","value":"UPF0216"}]},{"database":"NCBIfam","id":"NF003153","properties":[{"key":"EntryName","value":"PRK04115.1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01886","properties":[{"key":"EntryName","value":"DUF61"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF005264","properties":[{"key":"EntryName","value":"UCP005264"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MEKVDRIIQMEIGRINSHLPKARKSLCELLKEDSPSIELRDGSLHYFRRSELEFLKTLAGEEACLVKLPIILELSTLDRGYFVVRGRGEVRVIKKLLELSEDIYLEENTVRLPRYYLPTIRRKLPTTTVYAFITEW","length":136,"molWeight":15982,"crc64":"6ACBC4E3EDD3344D","md5":"5838D8E5E2EDDF029EFAFC4FE9D7D672"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI0000139825"}}