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Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1 (By similarity)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20551172"}],"value":"Protein modification; protein ubiquitination"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q9JLV2"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"19966799"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20551172"}],"value":"Component of the DCX(TRPC4AP) E3 ubiquitin ligase complex, at least composed of CUL4A, DDB1, TRPC4AP/TRUSS and RBX1 (PubMed:19966799, PubMed:20551172). Interacts with MYC (PubMed:20551172). Constitutively associated with TNFRSF1A (By similarity). Directly interacts with TRADD, TRAF2, CHUK, IKBKB and IKBKG (By similarity). 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