{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q8SV57","uniProtkbId":"Y6G8_ENCCU","entryAudit":{"firstPublicDate":"2004-08-31","lastAnnotationUpdateDate":"2025-06-18","lastSequenceUpdateDate":"2013-05-29","entryVersion":59,"sequenceVersion":2},"annotationScore":1.0,"organism":{"scientificName":"Encephalitozoon cuniculi (strain GB-M1)","commonName":"Microsporidian parasite","taxonId":284813,"lineage":["Eukaryota","Fungi","Fungi incertae sedis","Microsporidia","Unikaryonidae","Encephalitozoon"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"UPF0329 protein ECU06_1680"}}},"genes":[{"orderedLocusNames":[{"value":"ECU06_1680"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the UPF0329 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":440,"modifier":"EXACT"}},"description":"UPF0329 protein ECU06_1680","featureId":"PRO_0000223168"},{"type":"Region","location":{"start":{"value":150,"modifier":"EXACT"},"end":{"value":244,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":150,"modifier":"EXACT"},"end":{"value":186,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":234,"modifier":"EXACT"},"end":{"value":244,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"11719806","citationType":"journal article","authors":["Katinka M.D.","Duprat S.","Cornillot E.","Metenier G.","Thomarat F.","Prensier G.","Barbe V.","Peyretaillade E.","Brottier P.","Wincker P.","Delbac F.","El Alaoui H.","Peyret P.","Saurin W.","Gouy M.","Weissenbach J.","Vivares C.P."],"citationCrossReferences":[{"database":"PubMed","id":"11719806"},{"database":"DOI","id":"10.1038/35106579"}],"title":"Genome sequence and gene compaction of the eukaryote parasite Encephalitozoon cuniculi.","publicationDate":"2001","journal":"Nature","firstPage":"450","lastPage":"453","volume":"414"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"GB-M1","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"20003517","citationType":"journal article","authors":["Peyretaillade E.","Goncalves O.","Terrat S.","Dugat-Bony E.","Wincker P.","Cornman R.S.","Evans J.D.","Delbac F.","Peyret P."],"citationCrossReferences":[{"database":"PubMed","id":"20003517"},{"database":"DOI","id":"10.1186/1471-2164-10-607"}],"title":"Identification of transcriptional signals in Encephalitozoon cuniculi widespread among Microsporidia phylum: support for accurate structural genome annotation.","publicationDate":"2009","journal":"BMC Genomics","firstPage":"607","lastPage":"607","volume":"10"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"GB-M1","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AL590446","properties":[{"key":"ProteinId","value":"CAD25529.2"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"NP_585925.2","properties":[{"key":"NucleotideSequenceId","value":"NM_001041547.2"}]},{"database":"AlphaFoldDB","id":"Q8SV57","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q8SV57","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"284813.Q8SV57","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"859353","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecu:ECU06_1680","properties":[{"key":"Description","value":"-"}]},{"database":"VEuPathDB","id":"MicrosporidiaDB:ECU06_1680","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_035434_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q8SV57","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"2162691at2759","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000819","properties":[{"key":"Component","value":"Chromosome VI"}]},{"database":"InterPro","id":"IPR022115","properties":[{"key":"EntryName","value":"DUF3654"}]},{"database":"InterPro","id":"IPR011667","properties":[{"key":"EntryName","value":"UPF0329"}]},{"database":"Pfam","id":"PF07753","properties":[{"key":"EntryName","value":"DUF1609"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF12376","properties":[{"key":"EntryName","value":"DUF3654"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MRMLDDMIENPPAGMSEEEKKVYLEDWRSAKEWGGFLYSIERWERIAEVEKIVCNACKEICLGLREEELLGLLAEGGMKKTLKEEFSEDKAKDARYLEYIVVDDVLLLDAHREYGGEVTKELVRQMLLGKEGKDIDKRYVDRVAGVVRERQRKREEETERSVKELVGDEEKAKSKEEKAKSKEEKAKSKRGRKGKSASAPSEQEEEKKESEVEEAEQGGEVEALPVEVGGARSKGGKKKSKGGRKCFKIHRRVLRWTKSPEKIKEEWDKGSEERWKGRSLEEIKEQKIVHDITGVLELLRSEDADRFFMDAGKYRKGGSERQRMVAIGALETGGQRMTGVVEVGTFKDGDGCPVVYHLRFKPTSIGSIGDVINPGVVEASDVGRVDEGEECEDADKFVYPKGVRFETVKETGSFQIVWKNPSDTSEVLRRLIVYCRPCVI","length":440,"molWeight":50009,"crc64":"F99F85CC6D664146","md5":"0CF404EFB9B624B4887A9E2CE5E492C4"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Region":1,"Compositional bias":2},"uniParcId":"UPI000267E460"}}