{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q8R2U2","uniProtkbId":"RMP64_MOUSE","entryAudit":{"firstPublicDate":"2015-12-09","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2002-06-01","entryVersion":130,"sequenceVersion":1},"annotationScore":5.0,"organism":{"scientificName":"Mus musculus","commonName":"Mouse","taxonId":10090,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Glires","Rodentia","Myomorpha","Muroidea","Muridae","Murinae","Mus","Mus"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Nucleolus and neural progenitor protein"}},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"19906856"}],"value":"Neural progenitor protein"}}]},"genes":[{"geneName":{"value":"Rmp64"},"synonyms":[{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"19906856"},{"evidenceCode":"ECO:0000312","source":"MGI","id":"MGI:2384836"}],"value":"Nepro"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q6NW34"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"19906856"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"26178919"}],"value":"Specific component of the MRP ribonucleoprotein endoribonuclease, Rnase/Mrp complex, a ribonucleoprotein complex involved in pre-rRNA processing (By similarity). 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Clearly detected until 12.5 dpc, the expression decreases and disappears by 15.5 dpc (PubMed:19906856)"}],"commentType":"DEVELOPMENTAL STAGE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"26178919"}],"value":"Knockout embryos die prior to implantation with a failure to form a blastocyst. The number of nucleolus precursor bodies (NPBs) and nucleoli per nucleus is significantly higher in deficient embryos. 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