{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q8NEQ6","secondaryAccessions":["B3KXI9"],"uniProtkbId":"SRARP_HUMAN","entryAudit":{"firstPublicDate":"2006-07-25","lastAnnotationUpdateDate":"2026-06-10","lastSequenceUpdateDate":"2002-10-01","entryVersion":139,"sequenceVersion":1},"annotationScore":5.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:28339"}],"value":"Steroid receptor-associated and regulated protein"}},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"22341523"}],"value":"Estrogen receptor-related factor"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"22341523"}],"value":"ER-related factor"}]},{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"28915724"}],"value":"Steroid receptor-regulated protein"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:28339"}],"value":"SRARP"},"synonyms":[{"value":"C1orf64"},{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"22341523"}],"value":"ERRF"},{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"28915724"}],"value":"SSPR"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22341523"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"28915724"}],"value":"May regulate the transcriptional function of androgen and estrogen receptors"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"28915724"}],"value":"Interacts with 14-3-3 proteins (PubMed:28915724)"}],"commentType":"SUBUNIT"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q8NEQ6","intActId":"EBI-17858294"},"interactantTwo":{"uniProtKBAccession":"Q8N9N5-2","geneName":"BANP","intActId":"EBI-11524452"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8NEQ6","intActId":"EBI-17858294"},"interactantTwo":{"uniProtKBAccession":"Q53EP0-3","geneName":"FNDC3B","intActId":"EBI-10242151"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8NEQ6","intActId":"EBI-17858294"},"interactantTwo":{"uniProtKBAccession":"Q16656-4","geneName":"NRF1","intActId":"EBI-11742836"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8NEQ6","intActId":"EBI-17858294"},"interactantTwo":{"uniProtKBAccession":"Q2TAL8","geneName":"QRICH1","intActId":"EBI-2798044"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8NEQ6","intActId":"EBI-17858294"},"interactantTwo":{"uniProtKBAccession":"P04920","geneName":"SLC4A2","intActId":"EBI-1390787"},"numberOfExperiments":2,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8NEQ6","intActId":"EBI-17858294"},"interactantTwo":{"uniProtKBAccession":"O76024","geneName":"WFS1","intActId":"EBI-720609"},"numberOfExperiments":3,"organismDiffer":false}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22341523"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"28915724"}],"value":"Expressed in breast tumors with a higher expression level in estrogen receptor-positive cancers (PubMed:22341523, PubMed:28915724)"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22341523"}],"value":"Up-regulated in breast cancers (PubMed:22341523)"}],"commentType":"INDUCTION"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":169,"modifier":"EXACT"}},"description":"Steroid receptor-associated and regulated protein","featureId":"PRO_0000247124"},{"type":"Natural variant","location":{"start":{"value":52,"modifier":"EXACT"},"end":{"value":52,"modifier":"EXACT"}},"description":"in a breast cancer sample; somatic mutation","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16959974"}],"featureId":"VAR_035491","alternativeSequence":{"originalSequence":"G","alternativeSequences":["W"]}},{"type":"Natural variant","location":{"start":{"value":100,"modifier":"EXACT"},"end":{"value":100,"modifier":"EXACT"}},"description":"in a breast cancer sample; somatic mutation","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16959974"}],"featureId":"VAR_035492","alternativeSequence":{"originalSequence":"G","alternativeSequences":["W"]}},{"type":"Natural variant","location":{"start":{"value":112,"modifier":"EXACT"},"end":{"value":112,"modifier":"EXACT"}},"description":"in dbSNP:rs34950166","featureCrossReferences":[{"database":"dbSNP","id":"rs34950166"}],"featureId":"VAR_033654","alternativeSequence":{"originalSequence":"L","alternativeSequences":["F"]}}],"keywords":[{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"14702039","citationType":"journal article","authors":["Ota T.","Suzuki Y.","Nishikawa T.","Otsuki T.","Sugiyama T.","Irie R.","Wakamatsu A.","Hayashi K.","Sato H.","Nagai K.","Kimura K.","Makita H.","Sekine M.","Obayashi M.","Nishi T.","Shibahara T.","Tanaka T.","Ishii S.","Yamamoto J.","Saito K.","Kawai Y.","Isono Y.","Nakamura Y.","Nagahari K.","Murakami K.","Yasuda T.","Iwayanagi T.","Wagatsuma M.","Shiratori A.","Sudo H.","Hosoiri T.","Kaku Y.","Kodaira H.","Kondo H.","Sugawara M.","Takahashi M.","Kanda K.","Yokoi T.","Furuya T.","Kikkawa E.","Omura Y.","Abe K.","Kamihara K.","Katsuta N.","Sato K.","Tanikawa M.","Yamazaki M.","Ninomiya K.","Ishibashi T.","Yamashita H.","Murakawa K.","Fujimori K.","Tanai H.","Kimata M.","Watanabe M.","Hiraoka S.","Chiba Y.","Ishida S.","Ono Y.","Takiguchi S.","Watanabe S.","Yosida M.","Hotuta T.","Kusano J.","Kanehori K.","Takahashi-Fujii A.","Hara H.","Tanase T.-O.","Nomura Y.","Togiya S.","Komai F.","Hara R.","Takeuchi K.","Arita M.","Imose N.","Musashino K.","Yuuki H.","Oshima A.","Sasaki N.","Aotsuka S.","Yoshikawa Y.","Matsunawa H.","Ichihara T.","Shiohata N.","Sano S.","Moriya S.","Momiyama H.","Satoh N.","Takami S.","Terashima Y.","Suzuki O.","Nakagawa S.","Senoh A.","Mizoguchi H.","Goto Y.","Shimizu F.","Wakebe H.","Hishigaki H.","Watanabe T.","Sugiyama A.","Takemoto M.","Kawakami B.","Yamazaki M.","Watanabe K.","Kumagai A.","Itakura S.","Fukuzumi Y.","Fujimori Y.","Komiyama M.","Tashiro H.","Tanigami A.","Fujiwara T.","Ono T.","Yamada K.","Fujii Y.","Ozaki K.","Hirao M.","Ohmori Y.","Kawabata A.","Hikiji T.","Kobatake N.","Inagaki H.","Ikema Y.","Okamoto S.","Okitani R.","Kawakami T.","Noguchi S.","Itoh T.","Shigeta K.","Senba T.","Matsumura K.","Nakajima Y.","Mizuno T.","Morinaga M.","Sasaki M.","Togashi T.","Oyama M.","Hata H.","Watanabe M.","Komatsu T.","Mizushima-Sugano J.","Satoh T.","Shirai Y.","Takahashi Y.","Nakagawa K.","Okumura K.","Nagase T.","Nomura N.","Kikuchi H.","Masuho Y.","Yamashita R.","Nakai K.","Yada T.","Nakamura Y.","Ohara O.","Isogai T.","Sugano S."],"citationCrossReferences":[{"database":"PubMed","id":"14702039"},{"database":"DOI","id":"10.1038/ng1285"}],"title":"Complete sequencing and characterization of 21,243 full-length human cDNAs.","publicationDate":"2004","journal":"Nat. Genet.","firstPage":"40","lastPage":"45","volume":"36"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Thalamus","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"16710414","citationType":"journal article","authors":["Gregory S.G.","Barlow K.F.","McLay K.E.","Kaul R.","Swarbreck D.","Dunham A.","Scott C.E.","Howe K.L.","Woodfine K.","Spencer C.C.A.","Jones M.C.","Gillson C.","Searle S.","Zhou Y.","Kokocinski F.","McDonald L.","Evans R.","Phillips K.","Atkinson A.","Cooper R.","Jones C.","Hall R.E.","Andrews T.D.","Lloyd C.","Ainscough R.","Almeida J.P.","Ambrose K.D.","Anderson F.","Andrew R.W.","Ashwell R.I.S.","Aubin K.","Babbage A.K.","Bagguley C.L.","Bailey J.","Beasley H.","Bethel G.","Bird C.P.","Bray-Allen S.","Brown J.Y.","Brown A.J.","Buckley D.","Burton J.","Bye J.","Carder C.","Chapman J.C.","Clark S.Y.","Clarke G.","Clee C.","Cobley V.","Collier R.E.","Corby N.","Coville G.J.","Davies J.","Deadman R.","Dunn M.","Earthrowl M.","Ellington A.G.","Errington H.","Frankish A.","Frankland J.","French L.","Garner P.","Garnett J.","Gay L.","Ghori M.R.J.","Gibson R.","Gilby L.M.","Gillett W.","Glithero R.J.","Grafham D.V.","Griffiths C.","Griffiths-Jones S.","Grocock R.","Hammond S.","Harrison E.S.I.","Hart E.","Haugen E.","Heath P.D.","Holmes S.","Holt K.","Howden P.J.","Hunt A.R.","Hunt S.E.","Hunter G.","Isherwood J.","James R.","Johnson C.","Johnson D.","Joy A.","Kay M.","Kershaw J.K.","Kibukawa M.","Kimberley A.M.","King A.","Knights A.J.","Lad H.","Laird G.","Lawlor S.","Leongamornlert D.A.","Lloyd D.M.","Loveland J.","Lovell J.","Lush M.J.","Lyne R.","Martin S.","Mashreghi-Mohammadi M.","Matthews L.","Matthews N.S.W.","McLaren S.","Milne S.","Mistry S.","Moore M.J.F.","Nickerson T.","O'Dell C.N.","Oliver K.","Palmeiri A.","Palmer S.A.","Parker A.","Patel D.","Pearce A.V.","Peck A.I.","Pelan S.","Phelps K.","Phillimore B.J.","Plumb R.","Rajan J.","Raymond C.","Rouse G.","Saenphimmachak C.","Sehra H.K.","Sheridan E.","Shownkeen R.","Sims S.","Skuce C.D.","Smith M.","Steward C.","Subramanian S.","Sycamore N.","Tracey A.","Tromans A.","Van Helmond Z.","Wall M.","Wallis J.M.","White S.","Whitehead S.L.","Wilkinson J.E.","Willey D.L.","Williams H.","Wilming L.","Wray P.W.","Wu Z.","Coulson A.","Vaudin M.","Sulston J.E.","Durbin R.M.","Hubbard T.","Wooster R.","Dunham I.","Carter N.P.","McVean G.","Ross M.T.","Harrow J.","Olson M.V.","Beck S.","Rogers J.","Bentley D.R."],"citationCrossReferences":[{"database":"PubMed","id":"16710414"},{"database":"DOI","id":"10.1038/nature04727"}],"title":"The DNA sequence and biological annotation of human chromosome 1.","publicationDate":"2006","journal":"Nature","firstPage":"315","lastPage":"321","volume":"441"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":3,"citation":{"id":"CI-5GBDQ6B103N1E","citationType":"submission","authors":["Mural R.J.","Istrail S.","Sutton G.G.","Florea L.","Halpern A.L.","Mobarry C.M.","Lippert R.","Walenz B.","Shatkay H.","Dew I.","Miller J.R.","Flanigan M.J.","Edwards N.J.","Bolanos R.","Fasulo D.","Halldorsson B.V.","Hannenhalli S.","Turner R.","Yooseph S.","Lu F.","Nusskern D.R.","Shue B.C.","Zheng X.H.","Zhong F.","Delcher A.L.","Huson D.H.","Kravitz S.A.","Mouchard L.","Reinert K.","Remington K.A.","Clark A.G.","Waterman M.S.","Eichler E.E.","Adams M.D.","Hunkapiller M.W.","Myers E.W.","Venter J.C."],"publicationDate":"JUL-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":4,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Prostate","type":"TISSUE"}]},{"referenceNumber":5,"citation":{"id":"16959974","citationType":"journal article","authors":["Sjoeblom T.","Jones S.","Wood L.D.","Parsons D.W.","Lin J.","Barber T.D.","Mandelker D.","Leary R.J.","Ptak J.","Silliman N.","Szabo S.","Buckhaults P.","Farrell C.","Meeh P.","Markowitz S.D.","Willis J.","Dawson D.","Willson J.K.V.","Gazdar A.F.","Hartigan J.","Wu L.","Liu C.","Parmigiani G.","Park B.H.","Bachman K.E.","Papadopoulos N.","Vogelstein B.","Kinzler K.W.","Velculescu V.E."],"citationCrossReferences":[{"database":"PubMed","id":"16959974"},{"database":"DOI","id":"10.1126/science.1133427"}],"title":"The consensus coding sequences of human breast and colorectal cancers.","publicationDate":"2006","journal":"Science","firstPage":"268","lastPage":"274","volume":"314"},"referencePositions":["VARIANTS [LARGE SCALE ANALYSIS] TRP-52 AND TRP-100"]},{"referenceNumber":6,"citation":{"id":"22341523","citationType":"journal article","authors":["Su D.","Fu X.","Fan S.","Wu X.","Wang X.X.","Fu L.","Dong X.Y.","Ni J.J.","Fu L.","Zhu Z.","Dong J.T."],"citationCrossReferences":[{"database":"PubMed","id":"22341523"},{"database":"DOI","id":"10.1016/j.ajpath.2011.11.025"}],"title":"Role of ERRF, a novel ER-related nuclear factor, in the growth control of ER-positive human breast cancer cells.","publicationDate":"2012","journal":"Am. J. Pathol.","firstPage":"1189","lastPage":"1201","volume":"180"},"referencePositions":["TISSUE SPECIFICITY","INDUCTION"]},{"referenceNumber":7,"citation":{"id":"27125460","citationType":"journal article","authors":["Luo A.","Zhang X."],"citationCrossReferences":[{"database":"PubMed","id":"27125460"},{"database":"DOI","id":"10.1016/j.bbrc.2016.04.132"}],"title":"ERRF is essential for estrogen-estrogen receptor alpha signaling pathway in ER positive breast cancer cells.","publicationDate":"2016","journal":"Biochem. Biophys. Res. Commun.","firstPage":"400","lastPage":"405","volume":"474"},"referencePositions":["FUNCTION"]},{"referenceNumber":8,"citation":{"id":"28915724","citationType":"journal article","authors":["Naderi A."],"citationCrossReferences":[{"database":"PubMed","id":"28915724"},{"database":"DOI","id":"10.18632/oncotarget.17826"}],"title":"C1orf64 is a novel androgen receptor target gene and coregulator that interacts with 14-3-3 protein in breast cancer.","publicationDate":"2017","journal":"Oncotarget","firstPage":"57907","lastPage":"57933","volume":"8"},"referencePositions":["TISSUE SPECIFICITY","INTERACTION WITH 14-3-3 PROTEINS","FUNCTION"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AK127425","properties":[{"key":"ProteinId","value":"BAG54501.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AL355994","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CH471167","properties":[{"key":"ProteinId","value":"EAW51759.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC017946","properties":[{"key":"ProteinId","value":"AAH17946.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS166.1","properties":[{"key":"Description","value":"-"}]},{"database":"RefSeq","id":"NP_849162.1","properties":[{"key":"NucleotideSequenceId","value":"NM_178840.4"}]},{"database":"AlphaFoldDB","id":"Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"127222","properties":[{"key":"Interactions","value":"8"}]},{"database":"FunCoup","id":"Q8NEQ6","properties":[{"key":"Number of interactors","value":"289"}]},{"database":"IntAct","id":"Q8NEQ6","properties":[{"key":"Interactions","value":"7"}]},{"database":"STRING","id":"9606.ENSP00000332162","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"SRARP","properties":[{"key":"Description","value":"-"}]},{"database":"DMDM","id":"74751258","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000332162","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"73201","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"14459","properties":[{"key":"antibodies","value":"78 antibodies from 19 providers"}]},{"database":"DNASU","id":"149563","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENST00000329454.2","properties":[{"key":"ProteinId","value":"ENSP00000332162.2"},{"key":"GeneId","value":"ENSG00000183888.4"}]},{"database":"GeneID","id":"149563","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:149563","properties":[{"key":"Description","value":"-"}]},{"database":"MANE-Select","id":"ENST00000329454.2","properties":[{"key":"ProteinId","value":"ENSP00000332162.2"},{"key":"RefSeqNucleotideId","value":"NM_178840.4"},{"key":"RefSeqProteinId","value":"NP_849162.1"}]},{"database":"UCSC","id":"uc001axn.4","properties":[{"key":"OrganismName","value":"human"}]},{"database":"AGR","id":"HGNC:28339","properties":[{"key":"Description","value":"-"}]},{"database":"ClinPGx","id":"PA142672514","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"149563","properties":[{"key":"Description","value":"-"}]},{"database":"DisGeNET","id":"149563","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"SRARP","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:28339","properties":[{"key":"GeneName","value":"SRARP"}]},{"database":"HPA","id":"ENSG00000183888","properties":[{"key":"ExpressionPatterns","value":"Tissue enhanced (brain, breast, salivary gland)"}]},{"database":"MIM","id":"619448","properties":[{"key":"Type","value":"gene"}]},{"database":"OpenTargets","id":"ENSG00000183888","properties":[{"key":"Description","value":"-"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000183888","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502TD74","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00390000000265","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_110067_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"AHLTFII","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"9451422at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"Q8NEQ6","properties":[{"key":"Number of GO annotations","value":"4 GO annotations based on evolutionary models"}]},{"database":"PhylomeDB","id":"Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"PathwayCommons","id":"Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"SignaLink","id":"Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"Agora","id":"ENSG00000183888","properties":[{"key":"NominatedTarget","value":"-"}]},{"database":"BioGRID-ORCS","id":"149563","properties":[{"key":"hits","value":"18 hits in 1119 CRISPR screens"}]},{"database":"GenomeRNAi","id":"149563","properties":[{"key":"Description","value":"-"}]},{"database":"Pharos","id":"Q8NEQ6","properties":[{"key":"DevelopmentLevel","value":"Tbio"}]},{"database":"PRO","id":"PR:Q8NEQ6","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome 1"}]},{"database":"RNAct","id":"Q8NEQ6","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000183888","properties":[{"key":"ExpressionPatterns","value":"Expressed in medial globus pallidus and 91 other cell types or tissues"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"22341523"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"22341523"}]},{"database":"GO","id":"GO:0030331","properties":[{"key":"GoTerm","value":"F:nuclear estrogen receptor binding"},{"key":"GoEvidenceType","value":"IPI:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000353","source":"PubMed","id":"27125460"}]},{"database":"GO","id":"GO:0033148","properties":[{"key":"GoTerm","value":"P:positive regulation of intracellular estrogen receptor signaling pathway"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"27125460"}]},{"database":"InterPro","id":"IPR027852","properties":[{"key":"EntryName","value":"C1ORF64"}]},{"database":"PANTHER","id":"PTHR38494","properties":[{"key":"EntryName","value":"STEROID RECEPTOR-ASSOCIATED AND REGULATED PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR38494:SF1","properties":[{"key":"EntryName","value":"STEROID RECEPTOR-ASSOCIATED AND REGULATED PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF15547","properties":[{"key":"EntryName","value":"C1ORF64"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MAPSEDPRDWRANLKGTIRETGLETSSGGKLAGHQKTVPTAHLTFVIDCTHGKQLSLAATASPPQAPSPNRGLVTPPMKTYIVFCGENWPHLTRVTPMGGGCLAQARATLPLCRGSVASASFPVSPLCPQEVPEAKGKPVKAAPVRSSTWGTVKDSLKALSSCVCGQAD","length":169,"molWeight":17657,"crc64":"53902A504A22451D","md5":"6B089F5F2545B73CD9AF2B09B35DEDC3"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"INTERACTION":6,"TISSUE SPECIFICITY":1,"INDUCTION":1},"countByFeatureType":{"Chain":1,"Natural variant":3},"uniParcId":"UPI0000070801"}}