{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q8ND82","secondaryAccessions":["A8K2V8","Q9NXR3"],"uniProtkbId":"Z280C_HUMAN","entryAudit":{"firstPublicDate":"2006-03-21","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2002-10-01","entryVersion":180,"sequenceVersion":1},"annotationScore":4.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Zinc finger protein 280C"}},"alternativeNames":[{"fullName":{"value":"Suppressor of hairy wing homolog 3"}},{"fullName":{"value":"Zinc finger protein 633"}}]},"genes":[{"geneName":{"value":"ZNF280C"},"synonyms":[{"value":"SUHW3"},{"value":"ZNF633"}]}],"comments":[{"texts":[{"value":"May function as a transcription factor"}],"commentType":"FUNCTION"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q8ND82","intActId":"EBI-8831272"},"interactantTwo":{"uniProtKBAccession":"P83916","geneName":"CBX1","intActId":"EBI-78129"},"numberOfExperiments":5,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8ND82","intActId":"EBI-8831272"},"interactantTwo":{"uniProtKBAccession":"Q13185","geneName":"CBX3","intActId":"EBI-78176"},"numberOfExperiments":5,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8ND82","intActId":"EBI-8831272"},"interactantTwo":{"uniProtKBAccession":"P45973","geneName":"CBX5","intActId":"EBI-78219"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8ND82","intActId":"EBI-8831272"},"interactantTwo":{"uniProtKBAccession":"Q08379","geneName":"GOLGA2","intActId":"EBI-618309"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8ND82","intActId":"EBI-8831272"},"interactantTwo":{"uniProtKBAccession":"P60371","geneName":"KRTAP10-6","intActId":"EBI-12012928"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8ND82","intActId":"EBI-8831272"},"interactantTwo":{"uniProtKBAccession":"Q9H2G4","geneName":"TSPYL2","intActId":"EBI-947459"},"numberOfExperiments":3,"organismDiffer":false}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Nucleus","id":"SL-0191"}}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Miscellaneous discrepancy","sequence":"BAA90947.1","note":"Contaminating sequence. Potential poly-A sequence.","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":737,"modifier":"EXACT"}},"description":"Zinc finger protein 280C","featureId":"PRO_0000227975"},{"type":"Zinc finger","location":{"start":{"value":316,"modifier":"EXACT"},"end":{"value":338,"modifier":"EXACT"}},"description":"C2H2-type 1"},{"type":"Zinc finger","location":{"start":{"value":353,"modifier":"EXACT"},"end":{"value":376,"modifier":"EXACT"}},"description":"C2H2-type 2"},{"type":"Zinc finger","location":{"start":{"value":383,"modifier":"EXACT"},"end":{"value":406,"modifier":"EXACT"}},"description":"C2H2-type 3"},{"type":"Zinc finger","location":{"start":{"value":413,"modifier":"EXACT"},"end":{"value":436,"modifier":"EXACT"}},"description":"C2H2-type 4"},{"type":"Zinc finger","location":{"start":{"value":470,"modifier":"EXACT"},"end":{"value":492,"modifier":"EXACT"}},"description":"C2H2-type 5"},{"type":"Region","location":{"start":{"value":57,"modifier":"EXACT"},"end":{"value":137,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":176,"modifier":"EXACT"},"end":{"value":223,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":535,"modifier":"EXACT"},"end":{"value":602,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":57,"modifier":"EXACT"},"end":{"value":66,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":112,"modifier":"EXACT"},"end":{"value":123,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":176,"modifier":"EXACT"},"end":{"value":185,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":211,"modifier":"EXACT"},"end":{"value":223,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":535,"modifier":"EXACT"},"end":{"value":579,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":580,"modifier":"EXACT"},"end":{"value":602,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Modified residue","location":{"start":{"value":80,"modifier":"EXACT"},"end":{"value":80,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"18220336"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"20068231"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"23186163"}]},{"type":"Modified residue","location":{"start":{"value":223,"modifier":"EXACT"},"end":{"value":223,"modifier":"EXACT"}},"description":"Phosphothreonine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"23186163"}]},{"type":"Modified residue","location":{"start":{"value":227,"modifier":"EXACT"},"end":{"value":227,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"20068231"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"23186163"}]},{"type":"Modified residue","location":{"start":{"value":540,"modifier":"EXACT"},"end":{"value":540,"modifier":"EXACT"}},"description":"Phosphothreonine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"18669648"}]},{"type":"Cross-link","location":{"start":{"value":5,"modifier":"EXACT"},"end":{"value":5,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":10,"modifier":"EXACT"},"end":{"value":10,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":14,"modifier":"EXACT"},"end":{"value":14,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":33,"modifier":"EXACT"},"end":{"value":33,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25772364"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":55,"modifier":"EXACT"},"end":{"value":55,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":75,"modifier":"EXACT"},"end":{"value":75,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25218447"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25755297"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25772364"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":113,"modifier":"EXACT"},"end":{"value":113,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":126,"modifier":"EXACT"},"end":{"value":126,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25218447"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":167,"modifier":"EXACT"},"end":{"value":167,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25218447"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25755297"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25772364"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":174,"modifier":"EXACT"},"end":{"value":174,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25755297"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25772364"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":180,"modifier":"EXACT"},"end":{"value":180,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":187,"modifier":"EXACT"},"end":{"value":187,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":273,"modifier":"EXACT"},"end":{"value":273,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25218447"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25755297"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"25772364"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":522,"modifier":"EXACT"},"end":{"value":522,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":564,"modifier":"EXACT"},"end":{"value":564,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]},{"type":"Cross-link","location":{"start":{"value":574,"modifier":"EXACT"},"end":{"value":574,"modifier":"EXACT"}},"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"28112733"}]}],"keywords":[{"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"id":"KW-1017","category":"PTM","name":"Isopeptide bond"},{"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0677","category":"Domain","name":"Repeat"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"},{"id":"KW-0832","category":"PTM","name":"Ubl conjugation"},{"id":"KW-0862","category":"Ligand","name":"Zinc"},{"id":"KW-0863","category":"Domain","name":"Zinc-finger"}],"references":[{"referenceNumber":1,"citation":{"id":"14702039","citationType":"journal article","authors":["Ota T.","Suzuki Y.","Nishikawa T.","Otsuki T.","Sugiyama T.","Irie R.","Wakamatsu A.","Hayashi K.","Sato H.","Nagai K.","Kimura K.","Makita H.","Sekine M.","Obayashi M.","Nishi T.","Shibahara T.","Tanaka T.","Ishii S.","Yamamoto J.","Saito K.","Kawai Y.","Isono Y.","Nakamura Y.","Nagahari K.","Murakami K.","Yasuda T.","Iwayanagi T.","Wagatsuma M.","Shiratori A.","Sudo H.","Hosoiri T.","Kaku Y.","Kodaira H.","Kondo H.","Sugawara M.","Takahashi M.","Kanda K.","Yokoi T.","Furuya T.","Kikkawa E.","Omura Y.","Abe K.","Kamihara K.","Katsuta N.","Sato K.","Tanikawa M.","Yamazaki M.","Ninomiya K.","Ishibashi T.","Yamashita H.","Murakawa K.","Fujimori K.","Tanai H.","Kimata M.","Watanabe M.","Hiraoka S.","Chiba Y.","Ishida S.","Ono Y.","Takiguchi S.","Watanabe S.","Yosida M.","Hotuta T.","Kusano J.","Kanehori K.","Takahashi-Fujii A.","Hara H.","Tanase T.-O.","Nomura Y.","Togiya S.","Komai F.","Hara R.","Takeuchi K.","Arita M.","Imose N.","Musashino K.","Yuuki H.","Oshima A.","Sasaki N.","Aotsuka S.","Yoshikawa Y.","Matsunawa H.","Ichihara T.","Shiohata N.","Sano S.","Moriya S.","Momiyama H.","Satoh N.","Takami S.","Terashima Y.","Suzuki O.","Nakagawa S.","Senoh A.","Mizoguchi H.","Goto Y.","Shimizu F.","Wakebe H.","Hishigaki H.","Watanabe T.","Sugiyama A.","Takemoto M.","Kawakami B.","Yamazaki M.","Watanabe K.","Kumagai A.","Itakura S.","Fukuzumi Y.","Fujimori Y.","Komiyama M.","Tashiro H.","Tanigami A.","Fujiwara T.","Ono T.","Yamada K.","Fujii Y.","Ozaki K.","Hirao M.","Ohmori Y.","Kawabata A.","Hikiji T.","Kobatake N.","Inagaki H.","Ikema Y.","Okamoto S.","Okitani R.","Kawakami T.","Noguchi S.","Itoh T.","Shigeta K.","Senba T.","Matsumura K.","Nakajima Y.","Mizuno T.","Morinaga M.","Sasaki M.","Togashi T.","Oyama M.","Hata H.","Watanabe M.","Komatsu T.","Mizushima-Sugano J.","Satoh T.","Shirai Y.","Takahashi Y.","Nakagawa K.","Okumura K.","Nagase T.","Nomura N.","Kikuchi H.","Masuho Y.","Yamashita R.","Nakai K.","Yada T.","Nakamura Y.","Ohara O.","Isogai T.","Sugano S."],"citationCrossReferences":[{"database":"PubMed","id":"14702039"},{"database":"DOI","id":"10.1038/ng1285"}],"title":"Complete sequencing and characterization of 21,243 full-length human cDNAs.","publicationDate":"2004","journal":"Nat. Genet.","firstPage":"40","lastPage":"45","volume":"36"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Colon","type":"TISSUE"},{"value":"Tongue","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"17974005","citationType":"journal article","authors":["Bechtel S.","Rosenfelder H.","Duda A.","Schmidt C.P.","Ernst U.","Wellenreuther R.","Mehrle A.","Schuster C.","Bahr A.","Bloecker H.","Heubner D.","Hoerlein A.","Michel G.","Wedler H.","Koehrer K.","Ottenwaelder B.","Poustka A.","Wiemann S.","Schupp I."],"citationCrossReferences":[{"database":"PubMed","id":"17974005"},{"database":"DOI","id":"10.1186/1471-2164-8-399"}],"title":"The full-ORF clone resource of the German cDNA consortium.","publicationDate":"2007","journal":"BMC Genomics","firstPage":"399","lastPage":"399","volume":"8"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Testis","type":"TISSUE"}]},{"referenceNumber":3,"citation":{"id":"15772651","citationType":"journal article","authors":["Ross M.T.","Grafham D.V.","Coffey A.J.","Scherer S.","McLay K.","Muzny D.","Platzer M.","Howell G.R.","Burrows C.","Bird C.P.","Frankish A.","Lovell F.L.","Howe K.L.","Ashurst J.L.","Fulton R.S.","Sudbrak R.","Wen G.","Jones M.C.","Hurles M.E.","Andrews T.D.","Scott C.E.","Searle S.","Ramser J.","Whittaker A.","Deadman R.","Carter N.P.","Hunt S.E.","Chen R.","Cree A.","Gunaratne P.","Havlak P.","Hodgson A.","Metzker M.L.","Richards S.","Scott G.","Steffen D.","Sodergren E.","Wheeler D.A.","Worley K.C.","Ainscough R.","Ambrose K.D.","Ansari-Lari M.A.","Aradhya S.","Ashwell R.I.","Babbage A.K.","Bagguley C.L.","Ballabio A.","Banerjee R.","Barker G.E.","Barlow K.F.","Barrett I.P.","Bates K.N.","Beare D.M.","Beasley H.","Beasley O.","Beck A.","Bethel G.","Blechschmidt K.","Brady N.","Bray-Allen S.","Bridgeman A.M.","Brown A.J.","Brown M.J.","Bonnin D.","Bruford E.A.","Buhay C.","Burch P.","Burford D.","Burgess J.","Burrill W.","Burton J.","Bye J.M.","Carder C.","Carrel L.","Chako J.","Chapman J.C.","Chavez D.","Chen E.","Chen G.","Chen Y.","Chen Z.","Chinault C.","Ciccodicola A.","Clark S.Y.","Clarke G.","Clee C.M.","Clegg S.","Clerc-Blankenburg K.","Clifford K.","Cobley V.","Cole C.G.","Conquer J.S.","Corby N.","Connor R.E.","David R.","Davies J.","Davis C.","Davis J.","Delgado O.","Deshazo D.","Dhami P.","Ding Y.","Dinh H.","Dodsworth S.","Draper H.","Dugan-Rocha S.","Dunham A.","Dunn M.","Durbin K.J.","Dutta I.","Eades T.","Ellwood M.","Emery-Cohen A.","Errington H.","Evans K.L.","Faulkner L.","Francis F.","Frankland J.","Fraser A.E.","Galgoczy P.","Gilbert J.","Gill R.","Gloeckner G.","Gregory S.G.","Gribble S.","Griffiths C.","Grocock R.","Gu Y.","Gwilliam R.","Hamilton C.","Hart E.A.","Hawes A.","Heath P.D.","Heitmann K.","Hennig S.","Hernandez J.","Hinzmann B.","Ho S.","Hoffs M.","Howden P.J.","Huckle E.J.","Hume J.","Hunt P.J.","Hunt A.R.","Isherwood J.","Jacob L.","Johnson D.","Jones S.","de Jong P.J.","Joseph S.S.","Keenan S.","Kelly S.","Kershaw J.K.","Khan Z.","Kioschis P.","Klages S.","Knights A.J.","Kosiura A.","Kovar-Smith C.","Laird G.K.","Langford C.","Lawlor S.","Leversha M.","Lewis L.","Liu W.","Lloyd C.","Lloyd D.M.","Loulseged H.","Loveland J.E.","Lovell J.D.","Lozado R.","Lu J.","Lyne R.","Ma J.","Maheshwari M.","Matthews L.H.","McDowall J.","McLaren S.","McMurray A.","Meidl P.","Meitinger T.","Milne S.","Miner G.","Mistry S.L.","Morgan M.","Morris S.","Mueller I.","Mullikin J.C.","Nguyen N.","Nordsiek G.","Nyakatura G.","O'dell C.N.","Okwuonu G.","Palmer S.","Pandian R.","Parker D.","Parrish J.","Pasternak S.","Patel D.","Pearce A.V.","Pearson D.M.","Pelan S.E.","Perez L.","Porter K.M.","Ramsey Y.","Reichwald K.","Rhodes S.","Ridler K.A.","Schlessinger D.","Schueler M.G.","Sehra H.K.","Shaw-Smith C.","Shen H.","Sheridan E.M.","Shownkeen R.","Skuce C.D.","Smith M.L.","Sotheran E.C.","Steingruber H.E.","Steward C.A.","Storey R.","Swann R.M.","Swarbreck D.","Tabor P.E.","Taudien S.","Taylor T.","Teague B.","Thomas K.","Thorpe A.","Timms K.","Tracey A.","Trevanion S.","Tromans A.C.","d'Urso M.","Verduzco D.","Villasana D.","Waldron L.","Wall M.","Wang Q.","Warren J.","Warry G.L.","Wei X.","West A.","Whitehead S.L.","Whiteley M.N.","Wilkinson J.E.","Willey D.L.","Williams G.","Williams L.","Williamson A.","Williamson H.","Wilming L.","Woodmansey R.L.","Wray P.W.","Yen J.","Zhang J.","Zhou J.","Zoghbi H.","Zorilla S.","Buck D.","Reinhardt R.","Poustka A.","Rosenthal A.","Lehrach H.","Meindl A.","Minx P.J.","Hillier L.W.","Willard H.F.","Wilson R.K.","Waterston R.H.","Rice C.M.","Vaudin M.","Coulson A.","Nelson D.L.","Weinstock G.","Sulston J.E.","Durbin R.M.","Hubbard T.","Gibbs R.A.","Beck S.","Rogers J.","Bentley D.R."],"citationCrossReferences":[{"database":"PubMed","id":"15772651"},{"database":"DOI","id":"10.1038/nature03440"}],"title":"The DNA sequence of the human X chromosome.","publicationDate":"2005","journal":"Nature","firstPage":"325","lastPage":"337","volume":"434"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":4,"citation":{"id":"CI-5GBD0VIIJ7C63","citationType":"submission","authors":["Mural R.J.","Istrail S.","Sutton G.G.","Florea L.","Halpern A.L.","Mobarry C.M.","Lippert R.","Walenz B.","Shatkay H.","Dew I.","Miller J.R.","Flanigan M.J.","Edwards N.J.","Bolanos R.","Fasulo D.","Halldorsson B.V.","Hannenhalli S.","Turner R.","Yooseph S.","Lu F.","Nusskern D.R.","Shue B.C.","Zheng X.H.","Zhong F.","Delcher A.L.","Huson D.H.","Kravitz S.A.","Mouchard L.","Reinert K.","Remington K.A.","Clark A.G.","Waterman M.S.","Eichler E.E.","Adams M.D.","Hunkapiller M.W.","Myers E.W.","Venter J.C."],"publicationDate":"SEP-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":5,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Testis","type":"TISSUE"}]},{"referenceNumber":6,"citation":{"id":"17525332","citationType":"journal article","authors":["Matsuoka S.","Ballif B.A.","Smogorzewska A.","McDonald E.R. III","Hurov K.E.","Luo J.","Bakalarski C.E.","Zhao Z.","Solimini N.","Lerenthal Y.","Shiloh Y.","Gygi S.P.","Elledge S.J."],"citationCrossReferences":[{"database":"PubMed","id":"17525332"},{"database":"DOI","id":"10.1126/science.1140321"}],"title":"ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.","publicationDate":"2007","journal":"Science","firstPage":"1160","lastPage":"1166","volume":"316"},"referencePositions":["IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"],"referenceComments":[{"value":"Embryonic kidney","type":"TISSUE"}]},{"referenceNumber":7,"citation":{"id":"18220336","citationType":"journal article","authors":["Cantin G.T.","Yi W.","Lu B.","Park S.K.","Xu T.","Lee J.-D.","Yates J.R. III"],"citationCrossReferences":[{"database":"PubMed","id":"18220336"},{"database":"DOI","id":"10.1021/pr0705441"}],"title":"Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.","publicationDate":"2008","journal":"J. Proteome Res.","firstPage":"1346","lastPage":"1351","volume":"7"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-80","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"],"referenceComments":[{"value":"Cervix carcinoma","type":"TISSUE"}]},{"referenceNumber":8,"citation":{"id":"18669648","citationType":"journal article","authors":["Dephoure N.","Zhou C.","Villen J.","Beausoleil S.A.","Bakalarski C.E.","Elledge S.J.","Gygi S.P."],"citationCrossReferences":[{"database":"PubMed","id":"18669648"},{"database":"DOI","id":"10.1073/pnas.0805139105"}],"title":"A quantitative atlas of mitotic phosphorylation.","publicationDate":"2008","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"10762","lastPage":"10767","volume":"105"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-540","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"],"referenceComments":[{"value":"Cervix carcinoma","type":"TISSUE"}]},{"referenceNumber":9,"citation":{"id":"20068231","citationType":"journal article","authors":["Olsen J.V.","Vermeulen M.","Santamaria A.","Kumar C.","Miller M.L.","Jensen L.J.","Gnad F.","Cox J.","Jensen T.S.","Nigg E.A.","Brunak S.","Mann M."],"citationCrossReferences":[{"database":"PubMed","id":"20068231"},{"database":"DOI","id":"10.1126/scisignal.2000475"}],"title":"Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.","publicationDate":"2010","journal":"Sci. Signal.","firstPage":"RA3","lastPage":"RA3","volume":"3"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-80 AND SER-227","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"],"referenceComments":[{"value":"Cervix carcinoma","type":"TISSUE"}]},{"referenceNumber":10,"citation":{"id":"23186163","citationType":"journal article","authors":["Zhou H.","Di Palma S.","Preisinger C.","Peng M.","Polat A.N.","Heck A.J.","Mohammed S."],"citationCrossReferences":[{"database":"PubMed","id":"23186163"},{"database":"DOI","id":"10.1021/pr300630k"}],"title":"Toward a comprehensive characterization of a human cancer cell phosphoproteome.","publicationDate":"2013","journal":"J. Proteome Res.","firstPage":"260","lastPage":"271","volume":"12"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-80; THR-223 AND SER-227","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"],"referenceComments":[{"value":"Cervix carcinoma","type":"TISSUE"},{"value":"Erythroleukemia","type":"TISSUE"}]},{"referenceNumber":11,"citation":{"id":"25218447","citationType":"journal article","authors":["Hendriks I.A.","D'Souza R.C.","Yang B.","Verlaan-de Vries M.","Mann M.","Vertegaal A.C."],"citationCrossReferences":[{"database":"PubMed","id":"25218447"},{"database":"DOI","id":"10.1038/nsmb.2890"}],"title":"Uncovering global SUMOylation signaling networks in a site-specific manner.","publicationDate":"2014","journal":"Nat. Struct. Mol. Biol.","firstPage":"927","lastPage":"936","volume":"21"},"referencePositions":["SUMOYLATION [LARGE SCALE ANALYSIS] AT LYS-75; LYS-126; LYS-167 AND LYS-273","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":12,"citation":{"id":"25772364","citationType":"journal article","authors":["Hendriks I.A.","Treffers L.W.","Verlaan-de Vries M.","Olsen J.V.","Vertegaal A.C."],"citationCrossReferences":[{"database":"PubMed","id":"25772364"},{"database":"DOI","id":"10.1016/j.celrep.2015.02.033"}],"title":"SUMO-2 orchestrates chromatin modifiers in response to DNA damage.","publicationDate":"2015","journal":"Cell Rep.","firstPage":"1778","lastPage":"1791","volume":"10"},"referencePositions":["SUMOYLATION [LARGE SCALE ANALYSIS] AT LYS-33; LYS-75; LYS-167; LYS-174 AND LYS-273","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":13,"citation":{"id":"25755297","citationType":"journal article","authors":["Xiao Z.","Chang J.G.","Hendriks I.A.","Sigurdsson J.O.","Olsen J.V.","Vertegaal A.C."],"citationCrossReferences":[{"database":"PubMed","id":"25755297"},{"database":"DOI","id":"10.1074/mcp.o114.044792"}],"title":"System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.","publicationDate":"2015","journal":"Mol. Cell. Proteomics","firstPage":"1419","lastPage":"1434","volume":"14"},"referencePositions":["SUMOYLATION [LARGE SCALE ANALYSIS] AT LYS-75; LYS-167; LYS-174 AND LYS-273","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":14,"citation":{"id":"28112733","citationType":"journal article","authors":["Hendriks I.A.","Lyon D.","Young C.","Jensen L.J.","Vertegaal A.C.","Nielsen M.L."],"citationCrossReferences":[{"database":"PubMed","id":"28112733"},{"database":"DOI","id":"10.1038/nsmb.3366"}],"title":"Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.","publicationDate":"2017","journal":"Nat. Struct. Mol. Biol.","firstPage":"325","lastPage":"336","volume":"24"},"referencePositions":["SUMOYLATION [LARGE SCALE ANALYSIS] AT LYS-5; LYS-10; LYS-14; LYS-33; LYS-55; LYS-75; LYS-113; LYS-126; LYS-167; LYS-174; LYS-180; LYS-187; LYS-273; LYS-522; LYS-564 AND LYS-574","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AK000102","properties":[{"key":"ProteinId","value":"BAA90947.1"},{"key":"Status","value":"ALT_SEQ"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK290373","properties":[{"key":"ProteinId","value":"BAF83062.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AL834333","properties":[{"key":"ProteinId","value":"CAD39001.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AL023799","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AL139234","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CH471107","properties":[{"key":"ProteinId","value":"EAX11806.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC051728","properties":[{"key":"ProteinId","value":"AAH51728.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS14622.1","properties":[{"key":"Description","value":"-"}]},{"database":"RefSeq","id":"NP_060136.1","properties":[{"key":"NucleotideSequenceId","value":"NM_017666.5"}]},{"database":"AlphaFoldDB","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"120749","properties":[{"key":"Interactions","value":"65"}]},{"database":"ELM","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"Q8ND82","properties":[{"key":"Number of interactors","value":"1078"}]},{"database":"IntAct","id":"Q8ND82","properties":[{"key":"Interactions","value":"39"}]},{"database":"MINT","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"9606.ENSP00000360017","properties":[{"key":"Description","value":"-"}]},{"database":"CarbonylDB","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"Q8ND82","properties":[{"key":"glycosylation","value":"2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)"}]},{"database":"iPTMnet","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"SwissPalm","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"ZNF280C","properties":[{"key":"Description","value":"-"}]},{"database":"DMDM","id":"74751215","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000360017","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"72987","properties":[{"key":"Description","value":"-"}]},{"database":"Pumba","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"30167","properties":[{"key":"antibodies","value":"76 antibodies from 23 providers"}]},{"database":"DNASU","id":"55609","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENST00000370978.9","properties":[{"key":"ProteinId","value":"ENSP00000360017.4"},{"key":"GeneId","value":"ENSG00000056277.17"}]},{"database":"GeneID","id":"55609","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:55609","properties":[{"key":"Description","value":"-"}]},{"database":"MANE-Select","id":"ENST00000370978.9","properties":[{"key":"ProteinId","value":"ENSP00000360017.4"},{"key":"RefSeqNucleotideId","value":"NM_017666.5"},{"key":"RefSeqProteinId","value":"NP_060136.1"}]},{"database":"UCSC","id":"uc004evm.4","properties":[{"key":"OrganismName","value":"human"}]},{"database":"AGR","id":"HGNC:25955","properties":[{"key":"Description","value":"-"}]},{"database":"ClinPGx","id":"PA162409961","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"55609","properties":[{"key":"Description","value":"-"}]},{"database":"DisGeNET","id":"55609","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"ZNF280C","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:25955","properties":[{"key":"GeneName","value":"ZNF280C"}]},{"database":"HPA","id":"ENSG00000056277","properties":[{"key":"ExpressionPatterns","value":"Tissue enhanced (testis)"}]},{"database":"OpenTargets","id":"ENSG00000056277","properties":[{"key":"Description","value":"-"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000056277","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG1721","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00940000162128","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_010097_1_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"PKCNIQF","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"10032537at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"Q8ND82","properties":[{"key":"Number of GO annotations","value":"3 GO annotations based on evolutionary models"}]},{"database":"PhylomeDB","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"PathwayCommons","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"SignaLink","id":"Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"Agora","id":"ENSG00000056277","properties":[{"key":"NominatedTarget","value":"-"}]},{"database":"BioGRID-ORCS","id":"55609","properties":[{"key":"hits","value":"15 hits in 786 CRISPR screens"}]},{"database":"ChiTaRS","id":"ZNF280C","properties":[{"key":"OrganismName","value":"human"}]},{"database":"GenomeRNAi","id":"55609","properties":[{"key":"Description","value":"-"}]},{"database":"Pharos","id":"Q8ND82","properties":[{"key":"DevelopmentLevel","value":"Tdark"}]},{"database":"PRO","id":"PR:Q8ND82","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome X"}]},{"database":"RNAct","id":"Q8ND82","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000056277","properties":[{"key":"ExpressionPatterns","value":"Expressed in secondary oocyte and 118 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"Q8ND82","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0000981","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription factor activity, RNA polymerase II-specific"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0000978","properties":[{"key":"GoTerm","value":"F:RNA polymerase II cis-regulatory region sequence-specific DNA binding"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0006355","properties":[{"key":"GoTerm","value":"P:regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"FunFam","id":"3.30.160.60:FF:000298","properties":[{"key":"EntryName","value":"zinc finger protein 280D isoform X1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.160.60","properties":[{"key":"EntryName","value":"Classic Zinc Finger"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR025243","properties":[{"key":"EntryName","value":"DUF4195"}]},{"database":"InterPro","id":"IPR059074","properties":[{"key":"EntryName","value":"Znf-C2H2_Z280C_D"}]},{"database":"InterPro","id":"IPR036236","properties":[{"key":"EntryName","value":"Znf_C2H2_sf"}]},{"database":"InterPro","id":"IPR013087","properties":[{"key":"EntryName","value":"Znf_C2H2_type"}]},{"database":"InterPro","id":"IPR057618","properties":[{"key":"EntryName","value":"Znf_POGZ/Z280C-D-like"}]},{"database":"PANTHER","id":"PTHR24388","properties":[{"key":"EntryName","value":"ZINC FINGER PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR24388:SF62","properties":[{"key":"EntryName","value":"ZINC FINGER PROTEIN 280C"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13836","properties":[{"key":"EntryName","value":"DUF4195"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF25414","properties":[{"key":"EntryName","value":"zf-C2H2_Z280C_D"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF25429","properties":[{"key":"EntryName","value":"zf-POGZ"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00355","properties":[{"key":"EntryName","value":"ZnF_C2H2"},{"key":"MatchStatus","value":"9"}]},{"database":"SUPFAM","id":"SSF57667","properties":[{"key":"EntryName","value":"beta-beta-alpha zinc fingers"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00028","properties":[{"key":"EntryName","value":"ZINC_FINGER_C2H2_1"},{"key":"MatchStatus","value":"4"}]}],"sequence":{"value":"MDDDKPFQPKNISKMAELFMECEEEELEPWQKKVEETQDEDDDELIFVGEISSSKPAISNILNRGHSSSSSKGIKSEPHSPGIPEIFRTASQRCRDPPSNPVAASPRFHLVSKSSQSSVTVENASKPDFTKNSQVGSDNSSILLFDSTQESLPPSQDIPAIFREGMKNTSYVLKHPSTSKVNSVTPKKPKTSEDVPQINPSTSLPLIGSPPVTSSQVMLSKGTNTSSPYDAGADYLRACPKCNVQFNLLDPLKYHMKHCCPDMITKFLGVIVKSERPCDEDKTDSETGKLIMLVNEFYYGRHEGVTEKEPKTYTTFKCFSCSKVLKNNIRFMNHMKHHLELEKQNNESWENHTTCQHCYRQYPTPFQLQCHIESTHTPHEFSTICKICELSFETEHILLQHMKDTHKPGEMPYVCQVCQFRSSTFSDVEAHFRAAHENTKNLLCPFCLKVSKMATPYMNHYMKHQKKGVHRCPKCRLQFLTSKEKAEHKAQHRTFIKPKELEGLPPGAKVTIRASLGPLQSKLPTAPFGCAPGTSFLQVTPPTSQNTTARNPRKSNASRSKTSKLHATTSTASKVNTSKPRGRIAKSKAKPSYKQKRQRNRKNKMSLALKNIRCRRGIHKCIECHSKIKDFASHFSIYIHCSFCKYNTNCNKAFVNHMMSSHSNHPGKRFCIFKKHSGTLRGITLVCLKCDFLADSSGLDRMAKHLSQRKTHTCQVIIENVSKSTSTSEPTTGCSLK","length":737,"molWeight":83096,"crc64":"D9974B7F772FE840","md5":"B421219A59C496CDC302EFAA3FED3636"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"INTERACTION":6,"SUBCELLULAR LOCATION":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1,"Zinc finger":5,"Region":3,"Compositional bias":6,"Modified residue":4,"Cross-link":16},"uniParcId":"UPI0000071981"}}