{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q8N954","secondaryAccessions":["A0A0A0MSF9","A8K0D9","B7Z2G4","B8ZZ44"],"uniProtkbId":"GPT11_HUMAN","entryAudit":{"firstPublicDate":"2007-03-06","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2018-03-28","entryVersion":163,"sequenceVersion":4},"annotationScore":4.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"G patch domain-containing protein 11"}},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"20813266"}],"value":"Centromeric protein Y"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"20813266"}],"value":"CENP-Y"}]},{"fullName":{"value":"Coiled-coil domain-containing protein 75"}}]},"genes":[{"geneName":{"value":"GPATCH11"},"synonyms":[{"value":"CCDC75"}]}],"comments":[{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q8N954","intActId":"EBI-2555378"},"interactantTwo":{"uniProtKBAccession":"O60242","geneName":"ADGRB3","intActId":"EBI-2682765"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8N954","intActId":"EBI-2555378"},"interactantTwo":{"uniProtKBAccession":"O00560","geneName":"SDCBP","intActId":"EBI-727004"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8N954-2","intActId":"EBI-12178961"},"interactantTwo":{"uniProtKBAccession":"P35659","geneName":"DEK","intActId":"EBI-301977"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8N954-2","intActId":"EBI-12178961"},"interactantTwo":{"uniProtKBAccession":"Q9NRD5","geneName":"PICK1","intActId":"EBI-79165"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8N954-2","intActId":"EBI-12178961"},"interactantTwo":{"uniProtKBAccession":"O00560","geneName":"SDCBP","intActId":"EBI-727004"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8N954-2","intActId":"EBI-12178961"},"interactantTwo":{"uniProtKBAccession":"Q6S9Z5","geneName":"ZNF474","intActId":"EBI-17269964"},"numberOfExperiments":3,"organismDiffer":false}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"20813266"}],"value":"Chromosome, centromere, kinetochore","id":"SL-0149"}}]},{"commentType":"ALTERNATIVE PRODUCTS","events":["Alternative splicing"],"isoforms":[{"name":{"value":"1"},"isoformIds":["Q8N954-1"],"isoformSequenceStatus":"Displayed"},{"name":{"value":"2"},"isoformIds":["Q8N954-2"],"sequenceIds":["VSP_023505","VSP_023506"],"isoformSequenceStatus":"Described"}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the GPATCH11 family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"It is uncertain whether Met-1 or Met-27 is the initiator"}],"commentType":"CAUTION"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"BAH11850.1","note":"Truncated N-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":285,"modifier":"EXACT"}},"description":"G patch domain-containing protein 11","featureId":"PRO_0000279751"},{"type":"Domain","location":{"start":{"value":95,"modifier":"EXACT"},"end":{"value":141,"modifier":"EXACT"}},"description":"G-patch","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00092"}]},{"type":"Region","location":{"start":{"value":59,"modifier":"EXACT"},"end":{"value":84,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":218,"modifier":"EXACT"},"end":{"value":237,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Coiled coil","location":{"start":{"value":51,"modifier":"EXACT"},"end":{"value":87,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Compositional bias","location":{"start":{"value":218,"modifier":"EXACT"},"end":{"value":235,"modifier":"EXACT"}},"description":"Acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Modified residue","location":{"start":{"value":141,"modifier":"EXACT"},"end":{"value":141,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"23186163"}]},{"type":"Modified residue","location":{"start":{"value":149,"modifier":"EXACT"},"end":{"value":149,"modifier":"EXACT"}},"description":"N6-acetyllysine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"19608861"}]},{"type":"Alternative sequence","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":129,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"14702039"},{"evidenceCode":"ECO:0000303","source":"PubMed","id":"15489334"}],"featureId":"VSP_023505","alternativeSequence":{}},{"type":"Alternative sequence","location":{"start":{"value":130,"modifier":"EXACT"},"end":{"value":132,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"14702039"},{"evidenceCode":"ECO:0000303","source":"PubMed","id":"15489334"}],"featureId":"VSP_023506","alternativeSequence":{"originalSequence":"KTG","alternativeSequences":["MSR"]}}],"keywords":[{"id":"KW-0007","category":"PTM","name":"Acetylation"},{"id":"KW-0025","category":"Coding sequence diversity","name":"Alternative splicing"},{"id":"KW-0137","category":"Cellular component","name":"Centromere"},{"id":"KW-0158","category":"Cellular component","name":"Chromosome"},{"id":"KW-0175","category":"Domain","name":"Coiled coil"},{"id":"KW-0995","category":"Cellular component","name":"Kinetochore"},{"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"14702039","citationType":"journal article","authors":["Ota T.","Suzuki Y.","Nishikawa T.","Otsuki T.","Sugiyama T.","Irie R.","Wakamatsu A.","Hayashi K.","Sato H.","Nagai K.","Kimura K.","Makita H.","Sekine M.","Obayashi M.","Nishi T.","Shibahara T.","Tanaka T.","Ishii S.","Yamamoto J.","Saito K.","Kawai Y.","Isono Y.","Nakamura Y.","Nagahari K.","Murakami K.","Yasuda T.","Iwayanagi T.","Wagatsuma M.","Shiratori A.","Sudo H.","Hosoiri T.","Kaku Y.","Kodaira H.","Kondo H.","Sugawara M.","Takahashi M.","Kanda K.","Yokoi T.","Furuya T.","Kikkawa E.","Omura Y.","Abe K.","Kamihara K.","Katsuta N.","Sato K.","Tanikawa M.","Yamazaki M.","Ninomiya K.","Ishibashi T.","Yamashita H.","Murakawa K.","Fujimori K.","Tanai H.","Kimata M.","Watanabe M.","Hiraoka S.","Chiba Y.","Ishida S.","Ono Y.","Takiguchi S.","Watanabe S.","Yosida M.","Hotuta T.","Kusano J.","Kanehori K.","Takahashi-Fujii A.","Hara H.","Tanase T.-O.","Nomura Y.","Togiya S.","Komai F.","Hara R.","Takeuchi K.","Arita M.","Imose N.","Musashino K.","Yuuki H.","Oshima A.","Sasaki N.","Aotsuka S.","Yoshikawa Y.","Matsunawa H.","Ichihara T.","Shiohata N.","Sano S.","Moriya S.","Momiyama H.","Satoh N.","Takami S.","Terashima Y.","Suzuki O.","Nakagawa S.","Senoh A.","Mizoguchi H.","Goto Y.","Shimizu F.","Wakebe H.","Hishigaki H.","Watanabe T.","Sugiyama A.","Takemoto M.","Kawakami B.","Yamazaki M.","Watanabe K.","Kumagai A.","Itakura S.","Fukuzumi Y.","Fujimori Y.","Komiyama M.","Tashiro H.","Tanigami A.","Fujiwara T.","Ono T.","Yamada K.","Fujii Y.","Ozaki K.","Hirao M.","Ohmori Y.","Kawabata A.","Hikiji T.","Kobatake N.","Inagaki H.","Ikema Y.","Okamoto S.","Okitani R.","Kawakami T.","Noguchi S.","Itoh T.","Shigeta K.","Senba T.","Matsumura K.","Nakajima Y.","Mizuno T.","Morinaga M.","Sasaki M.","Togashi T.","Oyama M.","Hata H.","Watanabe M.","Komatsu T.","Mizushima-Sugano J.","Satoh T.","Shirai Y.","Takahashi Y.","Nakagawa K.","Okumura K.","Nagase T.","Nomura N.","Kikuchi H.","Masuho Y.","Yamashita R.","Nakai K.","Yada T.","Nakamura Y.","Ohara O.","Isogai T.","Sugano S."],"citationCrossReferences":[{"database":"PubMed","id":"14702039"},{"database":"DOI","id":"10.1038/ng1285"}],"title":"Complete sequencing and characterization of 21,243 full-length human cDNAs.","publicationDate":"2004","journal":"Nat. Genet.","firstPage":"40","lastPage":"45","volume":"36"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)","NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 8-285 (ISOFORM 1)"],"referenceComments":[{"value":"Brain","type":"TISSUE"},{"value":"Cerebellum","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"15815621","citationType":"journal article","authors":["Hillier L.W.","Graves T.A.","Fulton R.S.","Fulton L.A.","Pepin K.H.","Minx P.","Wagner-McPherson C.","Layman D.","Wylie K.","Sekhon M.","Becker M.C.","Fewell G.A.","Delehaunty K.D.","Miner T.L.","Nash W.E.","Kremitzki C.","Oddy L.","Du H.","Sun H.","Bradshaw-Cordum H.","Ali J.","Carter J.","Cordes M.","Harris A.","Isak A.","van Brunt A.","Nguyen C.","Du F.","Courtney L.","Kalicki J.","Ozersky P.","Abbott S.","Armstrong J.","Belter E.A.","Caruso L.","Cedroni M.","Cotton M.","Davidson T.","Desai A.","Elliott G.","Erb T.","Fronick C.","Gaige T.","Haakenson W.","Haglund K.","Holmes A.","Harkins R.","Kim K.","Kruchowski S.S.","Strong C.M.","Grewal N.","Goyea E.","Hou S.","Levy A.","Martinka S.","Mead K.","McLellan M.D.","Meyer R.","Randall-Maher J.","Tomlinson C.","Dauphin-Kohlberg S.","Kozlowicz-Reilly A.","Shah N.","Swearengen-Shahid S.","Snider J.","Strong J.T.","Thompson J.","Yoakum M.","Leonard S.","Pearman C.","Trani L.","Radionenko M.","Waligorski J.E.","Wang C.","Rock S.M.","Tin-Wollam A.-M.","Maupin R.","Latreille P.","Wendl M.C.","Yang S.-P.","Pohl C.","Wallis J.W.","Spieth J.","Bieri T.A.","Berkowicz N.","Nelson J.O.","Osborne J.","Ding L.","Meyer R.","Sabo A.","Shotland Y.","Sinha P.","Wohldmann P.E.","Cook L.L.","Hickenbotham M.T.","Eldred J.","Williams D.","Jones T.A.","She X.","Ciccarelli F.D.","Izaurralde E.","Taylor J.","Schmutz J.","Myers R.M.","Cox D.R.","Huang X.","McPherson J.D.","Mardis E.R.","Clifton S.W.","Warren W.C.","Chinwalla A.T.","Eddy S.R.","Marra M.A.","Ovcharenko I.","Furey T.S.","Miller W.","Eichler E.E.","Bork P.","Suyama M.","Torrents D.","Waterston R.H.","Wilson R.K."],"citationCrossReferences":[{"database":"PubMed","id":"15815621"},{"database":"DOI","id":"10.1038/nature03466"}],"title":"Generation and annotation of the DNA sequences of human chromosomes 2 and 4.","publicationDate":"2005","journal":"Nature","firstPage":"724","lastPage":"731","volume":"434"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":3,"citation":{"id":"CI-5GBD0VIIJ7C63","citationType":"submission","authors":["Mural R.J.","Istrail S.","Sutton G.G.","Florea L.","Halpern A.L.","Mobarry C.M.","Lippert R.","Walenz B.","Shatkay H.","Dew I.","Miller J.R.","Flanigan M.J.","Edwards N.J.","Bolanos R.","Fasulo D.","Halldorsson B.V.","Hannenhalli S.","Turner R.","Yooseph S.","Lu F.","Nusskern D.R.","Shue B.C.","Zheng X.H.","Zhong F.","Delcher A.L.","Huson D.H.","Kravitz S.A.","Mouchard L.","Reinert K.","Remington K.A.","Clark A.G.","Waterman M.S.","Eichler E.E.","Adams M.D.","Hunkapiller M.W.","Myers E.W.","Venter J.C."],"publicationDate":"SEP-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":4,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)"],"referenceComments":[{"value":"Testis","type":"TISSUE"}]},{"referenceNumber":5,"citation":{"id":"19608861","citationType":"journal article","authors":["Choudhary C.","Kumar C.","Gnad F.","Nielsen M.L.","Rehman M.","Walther T.C.","Olsen J.V.","Mann M."],"citationCrossReferences":[{"database":"PubMed","id":"19608861"},{"database":"DOI","id":"10.1126/science.1175371"}],"title":"Lysine acetylation targets protein complexes and co-regulates major cellular functions.","publicationDate":"2009","journal":"Science","firstPage":"834","lastPage":"840","volume":"325"},"referencePositions":["ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-149","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":6,"citation":{"id":"20813266","citationType":"journal article","authors":["Ohta S.","Bukowski-Wills J.C.","Sanchez-Pulido L.","Alves Fde L.","Wood L.","Chen Z.A.","Platani M.","Fischer L.","Hudson D.F.","Ponting C.P.","Fukagawa T.","Earnshaw W.C.","Rappsilber J."],"citationCrossReferences":[{"database":"PubMed","id":"20813266"},{"database":"DOI","id":"10.1016/j.cell.2010.07.047"}],"title":"The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics.","publicationDate":"2010","journal":"Cell","firstPage":"810","lastPage":"821","volume":"142"},"referencePositions":["SUBCELLULAR LOCATION"]},{"referenceNumber":7,"citation":{"id":"21269460","citationType":"journal article","authors":["Burkard T.R.","Planyavsky M.","Kaupe I.","Breitwieser F.P.","Buerckstuemmer T.","Bennett K.L.","Superti-Furga G.","Colinge J."],"citationCrossReferences":[{"database":"PubMed","id":"21269460"},{"database":"DOI","id":"10.1186/1752-0509-5-17"}],"title":"Initial characterization of the human central proteome.","publicationDate":"2011","journal":"BMC Syst. Biol.","firstPage":"17","lastPage":"17","volume":"5"},"referencePositions":["IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":8,"citation":{"id":"23186163","citationType":"journal article","authors":["Zhou H.","Di Palma S.","Preisinger C.","Peng M.","Polat A.N.","Heck A.J.","Mohammed S."],"citationCrossReferences":[{"database":"PubMed","id":"23186163"},{"database":"DOI","id":"10.1021/pr300630k"}],"title":"Toward a comprehensive characterization of a human cancer cell phosphoproteome.","publicationDate":"2013","journal":"J. Proteome Res.","firstPage":"260","lastPage":"271","volume":"12"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-141","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"],"referenceComments":[{"value":"Erythroleukemia","type":"TISSUE"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AK095667","properties":[{"key":"ProteinId","value":"BAC04602.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK289504","properties":[{"key":"ProteinId","value":"BAF82193.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK294697","properties":[{"key":"ProteinId","value":"BAH11850.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AC007899","properties":[{"key":"ProteinId","value":"AAY24316.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CH471053","properties":[{"key":"ProteinId","value":"EAX00410.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC071798","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"RefSeq","id":"NP_001265434.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001278505.2"}],"isoformId":"Q8N954-2"},{"database":"RefSeq","id":"NP_001309178.3","properties":[{"key":"NucleotideSequenceId","value":"NM_001322249.4"}]},{"database":"RefSeq","id":"NP_777591.4","properties":[{"key":"NucleotideSequenceId","value":"NM_174931.4"}]},{"database":"AlphaFoldDB","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"128977","properties":[{"key":"Interactions","value":"61"}]},{"database":"FunCoup","id":"Q8N954","properties":[{"key":"Number of interactors","value":"418"}]},{"database":"IntAct","id":"Q8N954","properties":[{"key":"Interactions","value":"51"}]},{"database":"MINT","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"9606.ENSP00000386772","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"Q8N954","properties":[{"key":"glycosylation","value":"2 sites, 1 O-linked glycan (1 site)"}]},{"database":"iPTMnet","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"GPATCH11","properties":[{"key":"Description","value":"-"}]},{"database":"DMDM","id":"294862520","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000386772","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"72488","properties":[{"key":"Description","value":"-"}],"isoformId":"Q8N954-1"},{"database":"ProteomicsDB","id":"72489","properties":[{"key":"Description","value":"-"}],"isoformId":"Q8N954-2"},{"database":"Pumba","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"52371","properties":[{"key":"antibodies","value":"120 antibodies from 15 providers"}]},{"database":"DNASU","id":"253635","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"253635","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:253635","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"uc002rpr.6","properties":[{"key":"OrganismName","value":"human"}],"isoformId":"Q8N954-1"},{"database":"UCSC","id":"uc010ezz.4","properties":[{"key":"OrganismName","value":"human"}]},{"database":"AGR","id":"HGNC:26768","properties":[{"key":"Description","value":"-"}]},{"database":"ClinPGx","id":"PA143485427","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"253635","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"GPATCH11","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:26768","properties":[{"key":"GeneName","value":"GPATCH11"}]},{"database":"MIM","id":"621183","properties":[{"key":"Type","value":"gene"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000152133","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG1994","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"InParanoid","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"786951at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"Q8N954","properties":[{"key":"Number of GO annotations","value":"1 GO annotation based on evolutionary models"}]},{"database":"PhylomeDB","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"PathwayCommons","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"SignaLink","id":"Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID-ORCS","id":"253635","properties":[{"key":"hits","value":"5 hits in 979 CRISPR screens"}]},{"database":"GenomeRNAi","id":"253635","properties":[{"key":"Description","value":"-"}]},{"database":"Pharos","id":"Q8N954","properties":[{"key":"DevelopmentLevel","value":"Tdark"}]},{"database":"PRO","id":"PR:Q8N954","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome 2"}]},{"database":"RNAct","id":"Q8N954","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000152133","properties":[{"key":"ExpressionPatterns","value":"Expressed in calcaneal tendon and 190 other cell types or tissues"}]},{"database":"GO","id":"GO:0000776","properties":[{"key":"GoTerm","value":"C:kinetochore"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"20813266"}]},{"database":"GO","id":"GO:0003676","properties":[{"key":"GoTerm","value":"F:nucleic acid binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"InterPro","id":"IPR025239","properties":[{"key":"EntryName","value":"DUF4187"}]},{"database":"InterPro","id":"IPR000467","properties":[{"key":"EntryName","value":"G_patch_dom"}]},{"database":"InterPro","id":"IPR039249","properties":[{"key":"EntryName","value":"GPATCH11"}]},{"database":"PANTHER","id":"PTHR21032","properties":[{"key":"EntryName","value":"G PATCH DOMAIN-CONTAINING PROTEIN 11"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR21032:SF0","properties":[{"key":"EntryName","value":"G PATCH DOMAIN-CONTAINING PROTEIN 11"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13821","properties":[{"key":"EntryName","value":"DUF4187"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01585","properties":[{"key":"EntryName","value":"G-patch"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM01173","properties":[{"key":"EntryName","value":"DUF4187"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00443","properties":[{"key":"EntryName","value":"G_patch"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50174","properties":[{"key":"EntryName","value":"G_PATCH"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MRSARSTALNRGEQRAVRYYSHMKLNMAEEEDYMSDSFINVQEDIRPGLPMLRQIREARRKEEKQQEANLKNRQKSLKEEEQERRDIGLKNALGCENKGFALLQKMGYKSGQALGKSGGGIVEPIPLNIKTGKSGIGHEASLKRKAEEKLESYRKKIHMKNQAEEKAAEQFRMRLKNKQDEMKLEGDLRRSQRACQQLDVQKNIQVPREAWYWLRLEEETEEDEEEKEQDEDEYKSEDLSVLEKLQILTSYLREEHLYCIWCGTAYEDKEDLSSNCPGPTSADHD","length":285,"molWeight":33277,"crc64":"BB24AFAA10A97F49","md5":"CC4A9666044A5D68605DAB89764D4E86"},"extraAttributes":{"countByCommentType":{"INTERACTION":6,"SUBCELLULAR LOCATION":1,"ALTERNATIVE PRODUCTS":2,"SIMILARITY":1,"CAUTION":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1,"Domain":1,"Region":2,"Coiled coil":1,"Compositional bias":1,"Modified residue":2,"Alternative sequence":2},"uniParcId":"UPI0000160624"}}