{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q8K214","secondaryAccessions":["B1AS51","Q9JME0"],"uniProtkbId":"SCMH1_MOUSE","entryAudit":{"firstPublicDate":"2005-03-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2002-10-01","entryVersion":166,"sequenceVersion":1},"annotationScore":5.0,"organism":{"scientificName":"Mus musculus","commonName":"Mouse","taxonId":10090,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Glires","Rodentia","Myomorpha","Muroidea","Muridae","Murinae","Mus","Mus"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Polycomb protein SCMH1"}},"alternativeNames":[{"fullName":{"value":"Sex comb on midleg homolog 1"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"MGI","id":"MGI:1352762"}],"value":"Scmh1"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Associates with Polycomb group (PcG) multiprotein complexes; the complex class is required to maintain the transcriptionally repressive state of some genes"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10653359"}],"value":"Associates with a PRC1-like complex (By similarity). Interacts with the SAM domain of PHC1 via its SAM domain in vitro"}],"commentType":"SUBUNIT"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q8K214","intActId":"EBI-445955"},"interactantTwo":{"uniProtKBAccession":"O88513","geneName":"Gmnn","intActId":"EBI-445922"},"numberOfExperiments":2,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"Q8K214","intActId":"EBI-445955"},"interactantTwo":{"uniProtKBAccession":"Q64028","geneName":"Phc1","intActId":"EBI-927346"},"numberOfExperiments":2,"organismDiffer":false}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Nucleus","id":"SL-0191"}}]},{"commentType":"ALTERNATIVE PRODUCTS","events":["Alternative splicing"],"isoforms":[{"name":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"1"},"isoformIds":["Q8K214-1"],"isoformSequenceStatus":"Displayed"},{"name":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10653359"}],"value":"2"},"isoformIds":["Q8K214-2"],"sequenceIds":["VSP_051680","VSP_051681"],"isoformSequenceStatus":"Described"}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10653359"}],"value":"Most abundant in testis. Moderate levels detected in heart, brain, lung, liver, skeletal muscle and kidney and lower levels in spleen"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10653359"}],"value":"Detected throughout embryogenesis. Expressed ubiquitously in 8.5 dpc embryos. At 10.5 dpc, strongly expressed in nervous system including hindbrain and spinal cord, and in the pharyngeal arches and visceral organs. By 14.5 dpc, strong expression is detected throughout the central nervous system, and in tongue, heart, midgut and urogenital regions"}],"commentType":"DEVELOPMENTAL STAGE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10653359"}],"value":"By retinoic acid in F9 and F19 embryonal carcinoma cell lines"}],"commentType":"INDUCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the SCM family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":706,"modifier":"EXACT"}},"description":"Polycomb protein SCMH1","featureId":"PRO_0000114335"},{"type":"Repeat","location":{"start":{"value":28,"modifier":"EXACT"},"end":{"value":126,"modifier":"EXACT"}},"description":"MBT 1"},{"type":"Repeat","location":{"start":{"value":134,"modifier":"EXACT"},"end":{"value":235,"modifier":"EXACT"}},"description":"MBT 2"},{"type":"Domain","location":{"start":{"value":597,"modifier":"EXACT"},"end":{"value":662,"modifier":"EXACT"}},"description":"SAM","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00184"}]},{"type":"Region","location":{"start":{"value":233,"modifier":"EXACT"},"end":{"value":350,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":576,"modifier":"EXACT"},"end":{"value":595,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":272,"modifier":"EXACT"},"end":{"value":283,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":304,"modifier":"EXACT"},"end":{"value":319,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":329,"modifier":"EXACT"},"end":{"value":340,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":576,"modifier":"EXACT"},"end":{"value":591,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Alternative sequence","location":{"start":{"value":662,"modifier":"EXACT"},"end":{"value":664,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"10653359"}],"featureId":"VSP_051680","alternativeSequence":{"originalSequence":"VFW","alternativeSequences":["GKF"]}},{"type":"Alternative sequence","location":{"start":{"value":665,"modifier":"EXACT"},"end":{"value":706,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"10653359"}],"featureId":"VSP_051681","alternativeSequence":{}}],"keywords":[{"id":"KW-0025","category":"Coding sequence diversity","name":"Alternative splicing"},{"id":"KW-0217","category":"Molecular function","name":"Developmental protein"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0677","category":"Domain","name":"Repeat"},{"id":"KW-0678","category":"Molecular function","name":"Repressor"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"10653359","citationType":"journal article","authors":["Tomotsune D.","Takihara Y.","Berger J.","Duhl D.","Joo S.","Kyba M.","Shirai M.","Ohta H.","Matsuda Y.","Honda B.M.","Simon J.","Shimada K.","Brock H.W.","Randazzo F."],"citationCrossReferences":[{"database":"PubMed","id":"10653359"},{"database":"DOI","id":"10.1046/j.1432-0436.1999.6540229.x"}],"title":"A novel member of murine polycomb-group proteins, Sex comb on midleg homolog protein, is highly conserved, and interacts with RAE28/mph1 in vitro.","publicationDate":"1999","journal":"Differentiation","firstPage":"229","lastPage":"239","volume":"65"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)","TISSUE SPECIFICITY","DEVELOPMENTAL STAGE","INDUCTION","INTERACTION WITH PHC1"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10653359"}],"value":"Brain","type":"TISSUE"},{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10653359"}],"value":"Neonatal brain","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000305"},{"evidenceCode":"ECO:0000312","source":"EMBL","id":"BAA90554.1"}]},{"referenceNumber":2,"citation":{"id":"19468303","citationType":"journal article","authors":["Church D.M.","Goodstadt L.","Hillier L.W.","Zody M.C.","Goldstein S.","She X.","Bult C.J.","Agarwala R.","Cherry J.L.","DiCuccio M.","Hlavina W.","Kapustin Y.","Meric P.","Maglott D.","Birtle Z.","Marques A.C.","Graves T.","Zhou S.","Teague B.","Potamousis K.","Churas C.","Place M.","Herschleb J.","Runnheim R.","Forrest D.","Amos-Landgraf J.","Schwartz D.C.","Cheng Z.","Lindblad-Toh K.","Eichler E.E.","Ponting C.P."],"citationCrossReferences":[{"database":"PubMed","id":"19468303"},{"database":"DOI","id":"10.1371/journal.pbio.1000112"}],"title":"Lineage-specific biology revealed by a finished genome assembly of the mouse.","publicationDate":"2009","journal":"PLoS Biol.","firstPage":"E1000112","lastPage":"E1000112","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"C57BL/6J","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)"],"referenceComments":[{"evidences":[{"evidenceCode":"ECO:0000312","source":"EMBL","id":"AAH34667.1"}],"value":"FVB/N","type":"STRAIN"},{"evidences":[{"evidenceCode":"ECO:0000312","source":"EMBL","id":"AAH34667.1"}],"value":"Mammary gland","type":"TISSUE"}],"evidences":[{"evidenceCode":"ECO:0000305"},{"evidenceCode":"ECO:0000312","source":"EMBL","id":"AAH34667.1"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB030906","properties":[{"key":"ProteinId","value":"BAA90554.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AL611924","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC034667","properties":[{"key":"ProteinId","value":"AAH34667.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS18589.1","properties":[{"key":"Description","value":"-"}],"isoformId":"Q8K214-2"},{"database":"CCDS","id":"CCDS51292.1","properties":[{"key":"Description","value":"-"}],"isoformId":"Q8K214-1"},{"database":"RefSeq","id":"NP_001153102.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001159630.2"}],"isoformId":"Q8K214-1"},{"database":"RefSeq","id":"NP_001366114.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001379185.1"}],"isoformId":"Q8K214-2"},{"database":"RefSeq","id":"NP_001391019.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001404090.1"}],"isoformId":"Q8K214-1"},{"database":"RefSeq","id":"NP_038911.1","properties":[{"key":"NucleotideSequenceId","value":"NM_013883.3"}],"isoformId":"Q8K214-2"},{"database":"RefSeq","id":"XP_017175742.1","properties":[{"key":"NucleotideSequenceId","value":"XM_017320253.2"}],"isoformId":"Q8K214-2"},{"database":"AlphaFoldDB","id":"Q8K214","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q8K214","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"205936","properties":[{"key":"Interactions","value":"5"}]},{"database":"DIP","id":"DIP-32567N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"Q8K214","properties":[{"key":"Number of interactors","value":"961"}]},{"database":"IntAct","id":"Q8K214","properties":[{"key":"Interactions","value":"5"}]},{"database":"STRING","id":"10090.ENSMUSP00000101908","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"Q8K214","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q8K214","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"10090-ENSMUSP00000101908","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q8K214","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"256927","properties":[{"key":"Description","value":"-"}],"isoformId":"Q8K214-1"},{"database":"ProteomicsDB","id":"256928","properties":[{"key":"Description","value":"-"}],"isoformId":"Q8K214-2"},{"database":"Antibodypedia","id":"32169","properties":[{"key":"antibodies","value":"231 antibodies from 24 providers"}]},{"database":"DNASU","id":"29871","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENSMUST00000000087.13","properties":[{"key":"ProteinId","value":"ENSMUSP00000000087.7"},{"key":"GeneId","value":"ENSMUSG00000000085.17"}],"isoformId":"Q8K214-2"},{"database":"Ensembl","id":"ENSMUST00000064991.13","properties":[{"key":"ProteinId","value":"ENSMUSP00000069813.7"},{"key":"GeneId","value":"ENSMUSG00000000085.17"}],"isoformId":"Q8K214-1"},{"database":"Ensembl","id":"ENSMUST00000106298.10","properties":[{"key":"ProteinId","value":"ENSMUSP00000101905.4"},{"key":"GeneId","value":"ENSMUSG00000000085.17"}],"isoformId":"Q8K214-2"},{"database":"Ensembl","id":"ENSMUST00000106301.8","properties":[{"key":"ProteinId","value":"ENSMUSP00000101908.2"},{"key":"GeneId","value":"ENSMUSG00000000085.17"}],"isoformId":"Q8K214-1"},{"database":"GeneID","id":"29871","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"mmu:29871","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"uc008und.2","properties":[{"key":"OrganismName","value":"mouse"}],"isoformId":"Q8K214-2"},{"database":"UCSC","id":"uc008une.2","properties":[{"key":"OrganismName","value":"mouse"}],"isoformId":"Q8K214-1"},{"database":"AGR","id":"MGI:1352762","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"22955","properties":[{"key":"Description","value":"-"}]},{"database":"MGI","id":"MGI:1352762","properties":[{"key":"GeneName","value":"Scmh1"}]},{"database":"VEuPathDB","id":"HostDB:ENSMUSG00000000085","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG3766","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00940000157999","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_015000_1_1_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q8K214","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"NKEFCSM","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"5912862at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q8K214","properties":[{"key":"Description","value":"-"}]},{"database":"Reactome","id":"R-MMU-3108214","properties":[{"key":"PathwayName","value":"SUMOylation of DNA damage response and repair proteins"}]},{"database":"Reactome","id":"R-MMU-3899300","properties":[{"key":"PathwayName","value":"SUMOylation of transcription cofactors"}]},{"database":"Reactome","id":"R-MMU-4551638","properties":[{"key":"PathwayName","value":"SUMOylation of chromatin organization proteins"}]},{"database":"Reactome","id":"R-MMU-4570464","properties":[{"key":"PathwayName","value":"SUMOylation of RNA binding proteins"}]},{"database":"Reactome","id":"R-MMU-8939243","properties":[{"key":"PathwayName","value":"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"}]},{"database":"Reactome","id":"R-MMU-8943724","properties":[{"key":"PathwayName","value":"Regulation of PTEN gene transcription"}]},{"database":"BioGRID-ORCS","id":"29871","properties":[{"key":"hits","value":"2 hits in 83 CRISPR screens"}]},{"database":"PRO","id":"PR:Q8K214","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000589","properties":[{"key":"Component","value":"Chromosome 4"}]},{"database":"RNAct","id":"Q8K214","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSMUSG00000000085","properties":[{"key":"ExpressionPatterns","value":"Expressed in saccule of membranous labyrinth and 250 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"Q8K214","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0010369","properties":[{"key":"GoTerm","value":"C:chromocenter"},{"key":"GoEvidenceType","value":"IDA:MGI"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"17215307"}]},{"database":"GO","id":"GO:0005654","properties":[{"key":"GoTerm","value":"C:nucleoplasm"},{"key":"GoEvidenceType","value":"ISO:GO_Central"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IDA:MGI"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"17215307"}]},{"database":"GO","id":"GO:0003682","properties":[{"key":"GoTerm","value":"F:chromatin binding"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0042393","properties":[{"key":"GoTerm","value":"F:histone binding"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0009952","properties":[{"key":"GoTerm","value":"P:anterior/posterior pattern specification"},{"key":"GoEvidenceType","value":"IMP:MGI"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"17215307"}]},{"database":"GO","id":"GO:0006338","properties":[{"key":"GoTerm","value":"P:chromatin remodeling"},{"key":"GoEvidenceType","value":"IMP:MGI"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"17215307"}]},{"database":"GO","id":"GO:0031507","properties":[{"key":"GoTerm","value":"P:heterochromatin formation"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0045892","properties":[{"key":"GoTerm","value":"P:negative regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0007283","properties":[{"key":"GoTerm","value":"P:spermatogenesis"},{"key":"GoEvidenceType","value":"IMP:MGI"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"17215307"}]},{"database":"CDD","id":"cd20105","properties":[{"key":"EntryName","value":"MBT_SCMH1_rpt1"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd20108","properties":[{"key":"EntryName","value":"MBT_SCMH1_rpt2"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd09578","properties":[{"key":"EntryName","value":"SAM_Scm"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.150.50:FF:000018","properties":[{"key":"EntryName","value":"Polycomb protein scmh1 isoform 4"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.90.1150.190:FF:000001","properties":[{"key":"EntryName","value":"Polycomb protein scmh1 isoform 4"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.30.30.140:FF:000016","properties":[{"key":"EntryName","value":"polycomb protein SCMH1 isoform X1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.30.30.140","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"2"}]},{"database":"Gene3D","id":"3.90.1150.190","properties":[{"key":"EntryName","value":"SLED domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.150.50","properties":[{"key":"EntryName","value":"Transcription Factor, Ets-1"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR004092","properties":[{"key":"EntryName","value":"Mbt"}]},{"database":"InterPro","id":"IPR047279","properties":[{"key":"EntryName","value":"MBT_SCMH1_rpt1"}]},{"database":"InterPro","id":"IPR047280","properties":[{"key":"EntryName","value":"MBT_SCMH1_rpt2"}]},{"database":"InterPro","id":"IPR050548","properties":[{"key":"EntryName","value":"PcG_chromatin_remod_factors"}]},{"database":"InterPro","id":"IPR001660","properties":[{"key":"EntryName","value":"SAM"}]},{"database":"InterPro","id":"IPR013761","properties":[{"key":"EntryName","value":"SAM/pointed_sf"}]},{"database":"InterPro","id":"IPR047531","properties":[{"key":"EntryName","value":"SAM_Scm-like"}]},{"database":"InterPro","id":"IPR033763","properties":[{"key":"EntryName","value":"SCML2_RBR"}]},{"database":"InterPro","id":"IPR021987","properties":[{"key":"EntryName","value":"SLED"}]},{"database":"InterPro","id":"IPR038348","properties":[{"key":"EntryName","value":"SLED_sf"}]},{"database":"PANTHER","id":"PTHR12247","properties":[{"key":"EntryName","value":"POLYCOMB GROUP PROTEIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR12247:SF68","properties":[{"key":"EntryName","value":"POLYCOMB PROTEIN SCMH1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02820","properties":[{"key":"EntryName","value":"MBT"},{"key":"MatchStatus","value":"2"}]},{"database":"Pfam","id":"PF17208","properties":[{"key":"EntryName","value":"RBR"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00536","properties":[{"key":"EntryName","value":"SAM_1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF12140","properties":[{"key":"EntryName","value":"SLED"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00561","properties":[{"key":"EntryName","value":"MBT"},{"key":"MatchStatus","value":"2"}]},{"database":"SMART","id":"SM00454","properties":[{"key":"EntryName","value":"SAM"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF47769","properties":[{"key":"EntryName","value":"SAM/Pointed domain"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF63748","properties":[{"key":"EntryName","value":"Tudor/PWWP/MBT"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS51079","properties":[{"key":"EntryName","value":"MBT"},{"key":"MatchStatus","value":"2"}]},{"database":"PROSITE","id":"PS50105","properties":[{"key":"EntryName","value":"SAM_DOMAIN"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MLVCYSVLACESLWDLPCSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSSEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIKIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGAEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPGTKVVIPKNPSPSSDVSTEKPSIHSTKTVLEHQPGQRGRKPGKKRGRTPKILIPHPTSTPSKSAEPLKFPKKRGPKPGSKRKPRTLLSPPPTSPTTSTPEPDTSTVPQDAATVPSSAMQAPTVCIYLNKSGSTGPHLDKKKIQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQGHGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFTQTHLSLTATEYNHNHDRYLPGETFVLGNSLARSLETHSDLMDSALKPANLVSTSQNLRTPGYRPLLPSCGLPLSTVSAVRRLCSKGVLKGKKERRDVESFWKLNHSPGSDRHLESRDPPRLSGRDPSSWTVEDVMQFVREADPQLGSHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSFHIDRLKQVFWKRETILWSREGLSREVWPISEDTALGHFFSGMDKVFGSLSKR","length":706,"molWeight":78669,"crc64":"CC7531B46A439E39","md5":"D089718BC577A40457A1AFB2C2EB8469"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"INTERACTION":2,"SUBCELLULAR LOCATION":1,"ALTERNATIVE PRODUCTS":2,"TISSUE SPECIFICITY":1,"DEVELOPMENTAL STAGE":1,"INDUCTION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Repeat":2,"Domain":1,"Region":2,"Compositional bias":4,"Alternative sequence":2},"uniParcId":"UPI00000E6638"}}