{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q78J03","uniProtkbId":"MSRB2_MOUSE","entryAudit":{"firstPublicDate":"2008-04-08","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2004-07-05","entryVersion":139,"sequenceVersion":1},"annotationScore":5.0,"organism":{"scientificName":"Mus musculus","commonName":"Mouse","taxonId":10090,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Glires","Rodentia","Myomorpha","Muroidea","Muridae","Murinae","Mus","Mus"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Methionine-R-sulfoxide reductase B2, mitochondrial"},"shortNames":[{"value":"MsrB2"}],"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q9JLC3"}],"value":"1.8.4.12"},{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q9JLC3"}],"value":"1.8.4.14"}]},"flag":"Precursor"},"genes":[{"geneName":{"value":"Msrb2"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14699060"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23911929"}],"value":"Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(R)-S-oxide-[protein] + [thioredoxin]-dithiol","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:24164"},{"database":"Rhea","id":"RHEA-COMP:10698"},{"database":"Rhea","id":"RHEA-COMP:10700"},{"database":"Rhea","id":"RHEA-COMP:12313"},{"database":"Rhea","id":"RHEA-COMP:12314"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:16044"},{"database":"ChEBI","id":"CHEBI:29950"},{"database":"ChEBI","id":"CHEBI:45764"},{"database":"ChEBI","id":"CHEBI:50058"}],"ecNumber":"1.8.4.12","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q9JLC3"}]}},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (R)-S-oxide + [thioredoxin]-dithiol","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:21260"},{"database":"Rhea","id":"RHEA-COMP:10698"},{"database":"Rhea","id":"RHEA-COMP:10700"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:29950"},{"database":"ChEBI","id":"CHEBI:50058"},{"database":"ChEBI","id":"CHEBI:57844"},{"database":"ChEBI","id":"CHEBI:58773"}],"ecNumber":"1.8.4.14","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q9JLC3"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Zn(2+)","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14699060"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:29105"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14699060"}],"value":"Binds 1 zinc ion per subunit."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14699060"}],"value":"Inhibited by high concentrations of substrate"}],"commentType":"ACTIVITY REGULATION"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14699060"}],"value":"Mitochondrion","id":"SL-0173"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the MsrB Met sulfoxide reductase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Transit peptide","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":42,"modifier":"EXACT"}},"description":"Mitochondrion","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Chain","location":{"start":{"value":43,"modifier":"EXACT"},"end":{"value":175,"modifier":"EXACT"}},"description":"Methionine-R-sulfoxide reductase B2, mitochondrial","featureId":"PRO_0000327243"},{"type":"Domain","location":{"start":{"value":44,"modifier":"EXACT"},"end":{"value":173,"modifier":"EXACT"}},"description":"MsrB","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU01126"}]},{"type":"Region","location":{"start":{"value":22,"modifier":"EXACT"},"end":{"value":46,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":162,"modifier":"EXACT"},"end":{"value":162,"modifier":"EXACT"}},"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU01126"}]},{"type":"Binding site","location":{"start":{"value":83,"modifier":"EXACT"},"end":{"value":83,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29105"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU01126"}],"ligand":{"name":"Zn(2+)","id":"ChEBI:CHEBI:29105"}},{"type":"Binding site","location":{"start":{"value":86,"modifier":"EXACT"},"end":{"value":86,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29105"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU01126"}],"ligand":{"name":"Zn(2+)","id":"ChEBI:CHEBI:29105"}},{"type":"Binding site","location":{"start":{"value":139,"modifier":"EXACT"},"end":{"value":139,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29105"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU01126"}],"ligand":{"name":"Zn(2+)","id":"ChEBI:CHEBI:29105"}},{"type":"Binding site","location":{"start":{"value":142,"modifier":"EXACT"},"end":{"value":142,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:29105"}],"evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU01126"}],"ligand":{"name":"Zn(2+)","id":"ChEBI:CHEBI:29105"}},{"type":"Helix","location":{"start":{"value":48,"modifier":"EXACT"},"end":{"value":51,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Helix","location":{"start":{"value":55,"modifier":"EXACT"},"end":{"value":61,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Helix","location":{"start":{"value":70,"modifier":"EXACT"},"end":{"value":72,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Beta strand","location":{"start":{"value":79,"modifier":"EXACT"},"end":{"value":87,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Beta strand","location":{"start":{"value":89,"modifier":"EXACT"},"end":{"value":92,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Helix","location":{"start":{"value":93,"modifier":"EXACT"},"end":{"value":95,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Turn","location":{"start":{"value":98,"modifier":"EXACT"},"end":{"value":101,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Beta strand","location":{"start":{"value":104,"modifier":"EXACT"},"end":{"value":108,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Helix","location":{"start":{"value":116,"modifier":"EXACT"},"end":{"value":119,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Beta strand","location":{"start":{"value":122,"modifier":"EXACT"},"end":{"value":127,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Beta strand","location":{"start":{"value":134,"modifier":"EXACT"},"end":{"value":142,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Beta strand","location":{"start":{"value":147,"modifier":"EXACT"},"end":{"value":150,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Helix","location":{"start":{"value":156,"modifier":"EXACT"},"end":{"value":158,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Beta strand","location":{"start":{"value":160,"modifier":"EXACT"},"end":{"value":163,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]},{"type":"Beta strand","location":{"start":{"value":168,"modifier":"EXACT"},"end":{"value":175,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2L1U"}]}],"keywords":[{"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"id":"KW-0496","category":"Cellular component","name":"Mitochondrion"},{"id":"KW-0560","category":"Molecular function","name":"Oxidoreductase"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0809","category":"Domain","name":"Transit peptide"},{"id":"KW-0862","category":"Ligand","name":"Zinc"}],"references":[{"referenceNumber":1,"citation":{"id":"19468303","citationType":"journal article","authors":["Church D.M.","Goodstadt L.","Hillier L.W.","Zody M.C.","Goldstein S.","She X.","Bult C.J.","Agarwala R.","Cherry J.L.","DiCuccio M.","Hlavina W.","Kapustin Y.","Meric P.","Maglott D.","Birtle Z.","Marques A.C.","Graves T.","Zhou S.","Teague B.","Potamousis K.","Churas C.","Place M.","Herschleb J.","Runnheim R.","Forrest D.","Amos-Landgraf J.","Schwartz D.C.","Cheng Z.","Lindblad-Toh K.","Eichler E.E.","Ponting C.P."],"citationCrossReferences":[{"database":"PubMed","id":"19468303"},{"database":"DOI","id":"10.1371/journal.pbio.1000112"}],"title":"Lineage-specific biology revealed by a finished genome assembly of the mouse.","publicationDate":"2009","journal":"PLoS Biol.","firstPage":"E1000112","lastPage":"E1000112","volume":"7"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"C57BL/6J","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"FVB/N","type":"STRAIN"},{"value":"Mammary tumor","type":"TISSUE"}]},{"referenceNumber":3,"citation":{"id":"14699060","citationType":"journal article","authors":["Kim H.-Y.","Gladyshev V.N."],"citationCrossReferences":[{"database":"PubMed","id":"14699060"},{"database":"DOI","id":"10.1091/mbc.e03-08-0629"}],"title":"Methionine sulfoxide reduction in mammals: characterization of methionine-R-sulfoxide reductases.","publicationDate":"2004","journal":"Mol. Biol. Cell","firstPage":"1055","lastPage":"1064","volume":"15"},"referencePositions":["FUNCTION","SUBCELLULAR LOCATION","ACTIVITY REGULATION","COFACTOR"]},{"referenceNumber":4,"citation":{"id":"23911929","citationType":"journal article","authors":["Lee B.C.","Peterfi Z.","Hoffmann F.W.","Moore R.E.","Kaya A.","Avanesov A.","Tarrago L.","Zhou Y.","Weerapana E.","Fomenko D.E.","Hoffmann P.R.","Gladyshev V.N."],"citationCrossReferences":[{"database":"PubMed","id":"23911929"},{"database":"DOI","id":"10.1016/j.molcel.2013.06.019"}],"title":"MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation.","publicationDate":"2013","journal":"Mol. Cell","firstPage":"397","lastPage":"404","volume":"51"},"referencePositions":["FUNCTION"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AL928806","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC021619","properties":[{"key":"ProteinId","value":"AAH21619.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS15714.1","properties":[{"key":"Description","value":"-"}]},{"database":"RefSeq","id":"NP_083895.1","properties":[{"key":"NucleotideSequenceId","value":"NM_029619.2"}]},{"database":"PDB","id":"2L1U","properties":[{"key":"Method","value":"NMR"},{"key":"Resolution","value":"-"},{"key":"Chains","value":"A=45-175"}]},{"database":"PDBsum","id":"2L1U","properties":[{"key":"Description","value":"-"}]},{"database":"AlphaFoldDB","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"BMRB","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"218140","properties":[{"key":"Interactions","value":"1"}]},{"database":"FunCoup","id":"Q78J03","properties":[{"key":"Number of interactors","value":"931"}]},{"database":"IntAct","id":"Q78J03","properties":[{"key":"Interactions","value":"1"}]},{"database":"STRING","id":"10090.ENSMUSP00000023856","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"Q78J03","properties":[{"key":"glycosylation","value":"1 site, 1 O-linked glycan (1 site)"}]},{"database":"iPTMnet","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"SwissPalm","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"10090-ENSMUSP00000023856","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"291526","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"25752","properties":[{"key":"antibodies","value":"179 antibodies from 29 providers"}]},{"database":"DNASU","id":"76467","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENSMUST00000023856.9","properties":[{"key":"ProteinId","value":"ENSMUSP00000023856.9"},{"key":"GeneId","value":"ENSMUSG00000023094.15"}]},{"database":"GeneID","id":"76467","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"mmu:76467","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"uc008imf.2","properties":[{"key":"OrganismName","value":"mouse"}]},{"database":"AGR","id":"MGI:1923717","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"22921","properties":[{"key":"Description","value":"-"}]},{"database":"MGI","id":"MGI:1923717","properties":[{"key":"GeneName","value":"Msrb2"}]},{"database":"VEuPathDB","id":"HostDB:ENSMUSG00000023094","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG0856","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00940000161673","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_031040_8_2_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"YDETTDW","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"44061at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"BRENDA","id":"1.8.4.12","properties":[{"key":"OrganismId","value":"3474"}]},{"database":"Reactome","id":"R-MMU-5676934","properties":[{"key":"PathwayName","value":"Protein repair"}]},{"database":"BioGRID-ORCS","id":"76467","properties":[{"key":"hits","value":"0 hits in 77 CRISPR screens"}]},{"database":"EvolutionaryTrace","id":"Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:Q78J03","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000589","properties":[{"key":"Component","value":"Chromosome 2"}]},{"database":"RNAct","id":"Q78J03","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSMUSG00000023094","properties":[{"key":"ExpressionPatterns","value":"Expressed in interventricular septum and 206 other cell types or tissues"}]},{"database":"GO","id":"GO:0005739","properties":[{"key":"GoTerm","value":"C:mitochondrion"},{"key":"GoEvidenceType","value":"IDA:HGNC-UCL"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"14699060"}]},{"database":"GO","id":"GO:0003779","properties":[{"key":"GoTerm","value":"F:actin binding"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"23911929"}]},{"database":"GO","id":"GO:0033745","properties":[{"key":"GoTerm","value":"F:L-methionine (R)-S-oxide reductase activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0033743","properties":[{"key":"GoTerm","value":"F:peptide-methionine (R)-S-oxide reductase activity"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"23911929"}]},{"database":"GO","id":"GO:0008270","properties":[{"key":"GoTerm","value":"F:zinc ion binding"},{"key":"GoEvidenceType","value":"IDA:HGNC-UCL"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"14699060"}]},{"database":"GO","id":"GO:0030041","properties":[{"key":"GoTerm","value":"P:actin filament polymerization"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"23911929"}]},{"database":"GO","id":"GO:0030091","properties":[{"key":"GoTerm","value":"P:protein repair"},{"key":"GoEvidenceType","value":"IDA:HGNC-UCL"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"14699060"}]},{"database":"GO","id":"GO:0006979","properties":[{"key":"GoTerm","value":"P:response to oxidative stress"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"2.170.150.20:FF:000006","properties":[{"key":"EntryName","value":"Peptide-methionine (R)-S-oxide reductase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.170.150.20","properties":[{"key":"EntryName","value":"Peptide methionine sulfoxide reductase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR028427","properties":[{"key":"EntryName","value":"Met_Sox_Rdtase_MsrB"}]},{"database":"InterPro","id":"IPR002579","properties":[{"key":"EntryName","value":"Met_Sox_Rdtase_MsrB_dom"}]},{"database":"InterPro","id":"IPR011057","properties":[{"key":"EntryName","value":"Mss4-like_sf"}]},{"database":"NCBIfam","id":"TIGR00357","properties":[{"key":"EntryName","value":"peptide-methionine (R)-S-oxide reductase MsrB"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10173","properties":[{"key":"EntryName","value":"METHIONINE SULFOXIDE REDUCTASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10173:SF37","properties":[{"key":"EntryName","value":"METHIONINE-R-SULFOXIDE REDUCTASE B2, MITOCHONDRIAL"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01641","properties":[{"key":"EntryName","value":"SelR"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF51316","properties":[{"key":"EntryName","value":"Mss4-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51790","properties":[{"key":"EntryName","value":"MSRB"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MARLLRALRGLPLLQAPGRLARGCAGSGSKDTGSLTKSKRSLSEADWQKKLTPEQFYVTREKGTEAPFSGMYLNNKETGMYHCVCCDSPLFSSEKKYCSGTGWPSFSEAYGSKGSDESHTGILRRLDTSLGCPRMEVVCKQCEAHLGHVFPDGPKPTGQRFCINSVALKFKPSKP","length":175,"molWeight":19157,"crc64":"916771737762C6A6","md5":"BEF020DB96392753BDC612D14513FF46"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":2,"COFACTOR":1,"ACTIVITY REGULATION":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Transit peptide":1,"Chain":1,"Domain":1,"Region":1,"Active site":1,"Binding site":4,"Helix":6,"Beta strand":8,"Turn":1},"uniParcId":"UPI00000220D3"}}