{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q6V702","secondaryAccessions":["E7EQ13","Q6ZQY4","Q8N4G9"],"uniProtkbId":"CF299_HUMAN","entryAudit":{"firstPublicDate":"2007-09-11","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2010-05-18","entryVersion":129,"sequenceVersion":4},"annotationScore":3.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Cilia- and flagella-associated protein 299"}}},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:28554"}],"value":"CFAP299"},"synonyms":[{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:28554"}],"value":"C4orf22"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q810M1"}],"value":"May be involved in spermatogenesis"}],"commentType":"FUNCTION"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q6V702","intActId":"EBI-25429087"},"interactantTwo":{"uniProtKBAccession":"Q16236","geneName":"NFE2L2","intActId":"EBI-2007911"},"numberOfExperiments":3,"organismDiffer":false}]},{"commentType":"SUBCELLULAR LOCATION","note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q810M1"}],"value":"Mainly cytoplasmic"}]},"subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q810M1"}],"value":"Cytoplasm","id":"SL-0086"}},{"location":{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"Q810M1"}],"value":"Nucleus","id":"SL-0191"}}]},{"commentType":"ALTERNATIVE PRODUCTS","events":["Alternative splicing"],"isoforms":[{"name":{"value":"2"},"isoformIds":["Q6V702-2"],"isoformSequenceStatus":"Displayed"},{"name":{"value":"1"},"isoformIds":["Q6V702-1"],"sequenceIds":["VSP_037233"],"isoformSequenceStatus":"Described"},{"name":{"value":"3"},"isoformIds":["Q6V702-3"],"sequenceIds":["VSP_037234","VSP_037235"],"isoformSequenceStatus":"Described"}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay"}],"commentType":"MISCELLANEOUS","molecule":"Isoform 3"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":233,"modifier":"EXACT"}},"description":"Cilia- and flagella-associated protein 299","featureId":"PRO_0000301955"},{"type":"Alternative sequence","location":{"start":{"value":111,"modifier":"EXACT"},"end":{"value":111,"modifier":"EXACT"}},"description":"in isoform 1","evidences":[{"evidenceCode":"ECO:0000303","source":"Reference","id":"Ref.1"}],"featureId":"VSP_037233","alternativeSequence":{"originalSequence":"S","alternativeSequences":["SLNQQETDAAHILKKQLA"]}},{"type":"Alternative sequence","location":{"start":{"value":112,"modifier":"EXACT"},"end":{"value":156,"modifier":"EXACT"}},"description":"in isoform 3","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"14702039"}],"featureId":"VSP_037234","alternativeSequence":{"originalSequence":"SVIFIRDRNSHGQEISGYIDYAHRLKTEDFEVYFTGKKRLLPRPT","alternativeSequences":["AGVQWHHLGSLQPLPPGFKEFSCFSLPSGWDYRHAPPHPVRDLYS"]}},{"type":"Alternative sequence","location":{"start":{"value":157,"modifier":"EXACT"},"end":{"value":233,"modifier":"EXACT"}},"description":"in isoform 3","evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"14702039"}],"featureId":"VSP_037235","alternativeSequence":{}},{"type":"Natural variant","location":{"start":{"value":138,"modifier":"EXACT"},"end":{"value":138,"modifier":"EXACT"}},"description":"in dbSNP:rs11947742","featureCrossReferences":[{"database":"dbSNP","id":"rs11947742"}],"featureId":"VAR_034913","alternativeSequence":{"originalSequence":"T","alternativeSequences":["M"]}},{"type":"Natural variant","location":{"start":{"value":220,"modifier":"EXACT"},"end":{"value":220,"modifier":"EXACT"}},"description":"in dbSNP:rs1052325","featureCrossReferences":[{"database":"dbSNP","id":"rs1052325"}],"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"15489334"},{"evidenceCode":"ECO:0000269","source":"Reference","id":"Ref.1"},{"evidenceCode":"ECO:0000269","source":"Reference","id":"Ref.4"}],"featureId":"VAR_034914","alternativeSequence":{"originalSequence":"V","alternativeSequences":["I"]}},{"type":"Sequence conflict","location":{"start":{"value":68,"modifier":"EXACT"},"end":{"value":68,"modifier":"EXACT"}},"description":"in Ref. 1; AAQ56723","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"A","alternativeSequences":["V"]}},{"type":"Sequence conflict","location":{"start":{"value":119,"modifier":"EXACT"},"end":{"value":119,"modifier":"EXACT"}},"description":"in Ref. 1; AAQ56723","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"R","alternativeSequences":["G"]}},{"type":"Helix","location":{"start":{"value":93,"modifier":"EXACT"},"end":{"value":107,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Beta strand","location":{"start":{"value":109,"modifier":"EXACT"},"end":{"value":119,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Beta strand","location":{"start":{"value":125,"modifier":"EXACT"},"end":{"value":131,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Helix","location":{"start":{"value":132,"modifier":"EXACT"},"end":{"value":138,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Helix","location":{"start":{"value":142,"modifier":"EXACT"},"end":{"value":145,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Beta strand","location":{"start":{"value":157,"modifier":"EXACT"},"end":{"value":162,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Turn","location":{"start":{"value":163,"modifier":"EXACT"},"end":{"value":166,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Beta strand","location":{"start":{"value":167,"modifier":"EXACT"},"end":{"value":169,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Beta strand","location":{"start":{"value":174,"modifier":"EXACT"},"end":{"value":182,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Beta strand","location":{"start":{"value":185,"modifier":"EXACT"},"end":{"value":190,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Turn","location":{"start":{"value":191,"modifier":"EXACT"},"end":{"value":193,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Beta strand","location":{"start":{"value":196,"modifier":"EXACT"},"end":{"value":198,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Beta strand","location":{"start":{"value":209,"modifier":"EXACT"},"end":{"value":213,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Beta strand","location":{"start":{"value":220,"modifier":"EXACT"},"end":{"value":228,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"9FGP"}]},{"type":"Sequence conflict","location":{"start":{"value":122,"modifier":"EXACT"},"end":{"value":122,"modifier":"EXACT"},"sequence":"Q6V702-1"},"description":"in Ref. 1; AAQ56723","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"I","alternativeSequences":["T"]}}],"keywords":[{"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"id":"KW-0025","category":"Coding sequence diversity","name":"Alternative splicing"},{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-357GJSJ445O5C","citationType":"submission","authors":["Zhou G.","Yu R.","Zheng G.","Li H.","Shen C.","Ke R.","Li M.","Xiao W.","Lin L.","Yang S."],"publicationDate":"JUL-2003","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)","VARIANT ILE-220"]},{"referenceNumber":2,"citation":{"id":"14702039","citationType":"journal article","authors":["Ota T.","Suzuki Y.","Nishikawa T.","Otsuki T.","Sugiyama T.","Irie R.","Wakamatsu A.","Hayashi K.","Sato H.","Nagai K.","Kimura K.","Makita H.","Sekine M.","Obayashi M.","Nishi T.","Shibahara T.","Tanaka T.","Ishii S.","Yamamoto J.","Saito K.","Kawai Y.","Isono Y.","Nakamura Y.","Nagahari K.","Murakami K.","Yasuda T.","Iwayanagi T.","Wagatsuma M.","Shiratori A.","Sudo H.","Hosoiri T.","Kaku Y.","Kodaira H.","Kondo H.","Sugawara M.","Takahashi M.","Kanda K.","Yokoi T.","Furuya T.","Kikkawa E.","Omura Y.","Abe K.","Kamihara K.","Katsuta N.","Sato K.","Tanikawa M.","Yamazaki M.","Ninomiya K.","Ishibashi T.","Yamashita H.","Murakawa K.","Fujimori K.","Tanai H.","Kimata M.","Watanabe M.","Hiraoka S.","Chiba Y.","Ishida S.","Ono Y.","Takiguchi S.","Watanabe S.","Yosida M.","Hotuta T.","Kusano J.","Kanehori K.","Takahashi-Fujii A.","Hara H.","Tanase T.-O.","Nomura Y.","Togiya S.","Komai F.","Hara R.","Takeuchi K.","Arita M.","Imose N.","Musashino K.","Yuuki H.","Oshima A.","Sasaki N.","Aotsuka S.","Yoshikawa Y.","Matsunawa H.","Ichihara T.","Shiohata N.","Sano S.","Moriya S.","Momiyama H.","Satoh N.","Takami S.","Terashima Y.","Suzuki O.","Nakagawa S.","Senoh A.","Mizoguchi H.","Goto Y.","Shimizu F.","Wakebe H.","Hishigaki H.","Watanabe T.","Sugiyama A.","Takemoto M.","Kawakami B.","Yamazaki M.","Watanabe K.","Kumagai A.","Itakura S.","Fukuzumi Y.","Fujimori Y.","Komiyama M.","Tashiro H.","Tanigami A.","Fujiwara T.","Ono T.","Yamada K.","Fujii Y.","Ozaki K.","Hirao M.","Ohmori Y.","Kawabata A.","Hikiji T.","Kobatake N.","Inagaki H.","Ikema Y.","Okamoto S.","Okitani R.","Kawakami T.","Noguchi S.","Itoh T.","Shigeta K.","Senba T.","Matsumura K.","Nakajima Y.","Mizuno T.","Morinaga M.","Sasaki M.","Togashi T.","Oyama M.","Hata H.","Watanabe M.","Komatsu T.","Mizushima-Sugano J.","Satoh T.","Shirai Y.","Takahashi Y.","Nakagawa K.","Okumura K.","Nagase T.","Nomura N.","Kikuchi H.","Masuho Y.","Yamashita R.","Nakai K.","Yada T.","Nakamura Y.","Ohara O.","Isogai T.","Sugano S."],"citationCrossReferences":[{"database":"PubMed","id":"14702039"},{"database":"DOI","id":"10.1038/ng1285"}],"title":"Complete sequencing and characterization of 21,243 full-length human cDNAs.","publicationDate":"2004","journal":"Nat. Genet.","firstPage":"40","lastPage":"45","volume":"36"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3)"],"referenceComments":[{"value":"Trachea","type":"TISSUE"}]},{"referenceNumber":3,"citation":{"id":"15815621","citationType":"journal article","authors":["Hillier L.W.","Graves T.A.","Fulton R.S.","Fulton L.A.","Pepin K.H.","Minx P.","Wagner-McPherson C.","Layman D.","Wylie K.","Sekhon M.","Becker M.C.","Fewell G.A.","Delehaunty K.D.","Miner T.L.","Nash W.E.","Kremitzki C.","Oddy L.","Du H.","Sun H.","Bradshaw-Cordum H.","Ali J.","Carter J.","Cordes M.","Harris A.","Isak A.","van Brunt A.","Nguyen C.","Du F.","Courtney L.","Kalicki J.","Ozersky P.","Abbott S.","Armstrong J.","Belter E.A.","Caruso L.","Cedroni M.","Cotton M.","Davidson T.","Desai A.","Elliott G.","Erb T.","Fronick C.","Gaige T.","Haakenson W.","Haglund K.","Holmes A.","Harkins R.","Kim K.","Kruchowski S.S.","Strong C.M.","Grewal N.","Goyea E.","Hou S.","Levy A.","Martinka S.","Mead K.","McLellan M.D.","Meyer R.","Randall-Maher J.","Tomlinson C.","Dauphin-Kohlberg S.","Kozlowicz-Reilly A.","Shah N.","Swearengen-Shahid S.","Snider J.","Strong J.T.","Thompson J.","Yoakum M.","Leonard S.","Pearman C.","Trani L.","Radionenko M.","Waligorski J.E.","Wang C.","Rock S.M.","Tin-Wollam A.-M.","Maupin R.","Latreille P.","Wendl M.C.","Yang S.-P.","Pohl C.","Wallis J.W.","Spieth J.","Bieri T.A.","Berkowicz N.","Nelson J.O.","Osborne J.","Ding L.","Meyer R.","Sabo A.","Shotland Y.","Sinha P.","Wohldmann P.E.","Cook L.L.","Hickenbotham M.T.","Eldred J.","Williams D.","Jones T.A.","She X.","Ciccarelli F.D.","Izaurralde E.","Taylor J.","Schmutz J.","Myers R.M.","Cox D.R.","Huang X.","McPherson J.D.","Mardis E.R.","Clifton S.W.","Warren W.C.","Chinwalla A.T.","Eddy S.R.","Marra M.A.","Ovcharenko I.","Furey T.S.","Miller W.","Eichler E.E.","Bork P.","Suyama M.","Torrents D.","Waterston R.H.","Wilson R.K."],"citationCrossReferences":[{"database":"PubMed","id":"15815621"},{"database":"DOI","id":"10.1038/nature03466"}],"title":"Generation and annotation of the DNA sequences of human chromosomes 2 and 4.","publicationDate":"2005","journal":"Nature","firstPage":"724","lastPage":"731","volume":"434"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":4,"citation":{"id":"CI-5GBDQ6B103N1E","citationType":"submission","authors":["Mural R.J.","Istrail S.","Sutton G.G.","Florea L.","Halpern A.L.","Mobarry C.M.","Lippert R.","Walenz B.","Shatkay H.","Dew I.","Miller J.R.","Flanigan M.J.","Edwards N.J.","Bolanos R.","Fasulo D.","Halldorsson B.V.","Hannenhalli S.","Turner R.","Yooseph S.","Lu F.","Nusskern D.R.","Shue B.C.","Zheng X.H.","Zhong F.","Delcher A.L.","Huson D.H.","Kravitz S.A.","Mouchard L.","Reinert K.","Remington K.A.","Clark A.G.","Waterman M.S.","Eichler E.E.","Adams M.D.","Hunkapiller M.W.","Myers E.W.","Venter J.C."],"publicationDate":"JUL-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]","VARIANT ILE-220"]},{"referenceNumber":5,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)","VARIANT ILE-220"],"referenceComments":[{"value":"Brain","type":"TISSUE"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AY349359","properties":[{"key":"ProteinId","value":"AAQ56723.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK128642","properties":[{"key":"ProteinId","value":"BAC87545.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AC021127","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AC093876","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AC093883","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AC098822","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AC105917","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CH471057","properties":[{"key":"ProteinId","value":"EAX05864.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BC034296","properties":[{"key":"ProteinId","value":"AAH34296.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS3587.1","properties":[{"key":"Description","value":"-"}],"isoformId":"Q6V702-2"},{"database":"CCDS","id":"CCDS56336.1","properties":[{"key":"Description","value":"-"}],"isoformId":"Q6V702-1"},{"database":"RefSeq","id":"NP_001193926.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001206997.2"}],"isoformId":"Q6V702-1"},{"database":"RefSeq","id":"NP_689983.2","properties":[{"key":"NucleotideSequenceId","value":"NM_152770.3"}],"isoformId":"Q6V702-2"},{"database":"PDB","id":"8J07","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"4.10 A"},{"key":"Chains","value":"i3=1-233"}]},{"database":"PDB","id":"9FGP","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"1.49 A"},{"key":"Chains","value":"A/B=92-229"}]},{"database":"PDBsum","id":"8J07","properties":[{"key":"Description","value":"-"}]},{"database":"PDBsum","id":"9FGP","properties":[{"key":"Description","value":"-"}]},{"database":"AlphaFoldDB","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"EMDB","id":"EMD-35888","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"129077","properties":[{"key":"Interactions","value":"12"}]},{"database":"FunCoup","id":"Q6V702","properties":[{"key":"Number of interactors","value":"476"}]},{"database":"IntAct","id":"Q6V702","properties":[{"key":"Interactions","value":"4"}]},{"database":"STRING","id":"9606.ENSP00000425786","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"C4orf22","properties":[{"key":"Description","value":"-"}]},{"database":"DMDM","id":"296439464","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000425786","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"17485","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"67716","properties":[{"key":"Description","value":"-"}],"isoformId":"Q6V702-2"},{"database":"ProteomicsDB","id":"67717","properties":[{"key":"Description","value":"-"}],"isoformId":"Q6V702-1"},{"database":"ProteomicsDB","id":"67718","properties":[{"key":"Description","value":"-"}],"isoformId":"Q6V702-3"},{"database":"Antibodypedia","id":"51658","properties":[{"key":"antibodies","value":"105 antibodies from 15 providers"}]},{"database":"DNASU","id":"255119","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENST00000358105.8","properties":[{"key":"ProteinId","value":"ENSP00000350818.3"},{"key":"GeneId","value":"ENSG00000197826.13"}],"isoformId":"Q6V702-2"},{"database":"Ensembl","id":"ENST00000508675.1","properties":[{"key":"ProteinId","value":"ENSP00000425786.1"},{"key":"GeneId","value":"ENSG00000197826.13"}],"isoformId":"Q6V702-1"},{"database":"GeneID","id":"255119","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:255119","properties":[{"key":"Description","value":"-"}]},{"database":"MANE-Select","id":"ENST00000358105.8","properties":[{"key":"ProteinId","value":"ENSP00000350818.3"},{"key":"RefSeqNucleotideId","value":"NM_152770.3"},{"key":"RefSeqProteinId","value":"NP_689983.2"}]},{"database":"UCSC","id":"uc003hmf.3","properties":[{"key":"OrganismName","value":"human"}],"isoformId":"Q6V702-2"},{"database":"AGR","id":"HGNC:28554","properties":[{"key":"Description","value":"-"}]},{"database":"ClinPGx","id":"PA145008853","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"255119","properties":[{"key":"Description","value":"-"}]},{"database":"DisGeNET","id":"255119","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"CFAP299","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:28554","properties":[{"key":"GeneName","value":"CFAP299"}]},{"database":"HPA","id":"ENSG00000197826","properties":[{"key":"ExpressionPatterns","value":"Group enriched (fallopian tube, testis)"}]},{"database":"MIM","id":"621388","properties":[{"key":"Type","value":"gene"}]},{"database":"OpenTargets","id":"ENSG00000197826","properties":[{"key":"Description","value":"-"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000197826","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502QSP8","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00390000016547","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_070912_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"FNNYQEY","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"2136125at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"Q6V702","properties":[{"key":"Number of GO annotations","value":"0 GO annotations based on evolutionary models"}]},{"database":"PhylomeDB","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"PathwayCommons","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"SignaLink","id":"Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"Agora","id":"ENSG00000197826","properties":[{"key":"NominatedTarget","value":"-"}]},{"database":"BioGRID-ORCS","id":"255119","properties":[{"key":"hits","value":"9 hits in 1111 CRISPR screens"}]},{"database":"ChiTaRS","id":"C4orf22","properties":[{"key":"OrganismName","value":"human"}]},{"database":"GenomeRNAi","id":"255119","properties":[{"key":"Description","value":"-"}]},{"database":"Pharos","id":"Q6V702","properties":[{"key":"DevelopmentLevel","value":"Tdark"}]},{"database":"PRO","id":"PR:Q6V702","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome 4"}]},{"database":"RNAct","id":"Q6V702","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000197826","properties":[{"key":"ExpressionPatterns","value":"Expressed in bronchial epithelial cell and 123 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"Q6V702","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"ISS:UniProtKB"}]},{"database":"InterPro","id":"IPR027887","properties":[{"key":"EntryName","value":"DUF4464"}]},{"database":"PANTHER","id":"PTHR33588","properties":[{"key":"EntryName","value":"CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33588:SF1","properties":[{"key":"EntryName","value":"CILIA- AND FLAGELLA-ASSOCIATED PROTEIN 299"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF14713","properties":[{"key":"EntryName","value":"DUF4464"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDQEEGLKALDNIVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDLQDNFLTALAMREEDNRSGKLSSVIFIRDRNSHGQEISGYIDYAHRLKTEDFEVYFTGKKRLLPRPTDISFYNWDADIAVSNSSPNYQVIADNPEGLLFRYKRDRKILNVDPKAQPGDNSTRITILTELYVQAVIFDHISRRKT","length":233,"molWeight":26869,"crc64":"D57F4BA59DDC2D65","md5":"0F43CC4C374970613F1AAB8EBD40ADED"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"INTERACTION":1,"SUBCELLULAR LOCATION":1,"ALTERNATIVE PRODUCTS":3,"MISCELLANEOUS":1},"countByFeatureType":{"Chain":1,"Alternative sequence":3,"Natural variant":2,"Sequence conflict":3,"Helix":3,"Beta strand":9,"Turn":2},"uniParcId":"UPI00001AF0C8"}}