{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q67XV7","secondaryAccessions":["Q682D7","Q682U5","Q9S7P7"],"uniProtkbId":"LOR3_ARATH","entryAudit":{"firstPublicDate":"2010-10-05","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2010-10-05","entryVersion":127,"sequenceVersion":2},"annotationScore":2.0,"organism":{"scientificName":"Arabidopsis thaliana","commonName":"Mouse-ear cress","taxonId":3702,"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Brassicales","Brassicaceae","Camelineae","Arabidopsis"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"value":"Protein LURP-one-related 3"}}},"genes":[{"orderedLocusNames":[{"value":"At1g53890"}],"orfNames":[{"value":"T18A20.12"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Might be related to the phospholipid scramblase and tubby-like superfamily of membrane tethered transcription factors"}],"commentType":"FUNCTION"},{"commentType":"ALTERNATIVE PRODUCTS","events":["Alternative splicing"],"isoforms":[{"name":{"value":"1"},"isoformIds":["Q67XV7-1"],"isoformSequenceStatus":"Displayed"},{"name":{"value":"2"},"isoformIds":["Q67XV7-2"],"sequenceIds":["VSP_039834","VSP_039835"],"isoformSequenceStatus":"Described"}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the LOR family"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"AAF02862.1","note":"Truncated N-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":217,"modifier":"EXACT"}},"description":"Protein LURP-one-related 3","featureId":"PRO_0000399235"},{"type":"Alternative sequence","location":{"start":{"value":195,"modifier":"EXACT"},"end":{"value":202,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"Reference","id":"Ref.4"}],"featureId":"VSP_039834","alternativeSequence":{"originalSequence":"EPQLDHSL","alternativeSequences":["VILKVSMF"]}},{"type":"Alternative sequence","location":{"start":{"value":203,"modifier":"EXACT"},"end":{"value":217,"modifier":"EXACT"}},"description":"in isoform 2","evidences":[{"evidenceCode":"ECO:0000303","source":"Reference","id":"Ref.4"}],"featureId":"VSP_039835","alternativeSequence":{}},{"type":"Sequence conflict","location":{"start":{"value":15,"modifier":"EXACT"},"end":{"value":15,"modifier":"EXACT"}},"description":"in Ref. 4; BAD43193","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"K","alternativeSequences":["E"]}},{"type":"Sequence conflict","location":{"start":{"value":31,"modifier":"EXACT"},"end":{"value":31,"modifier":"EXACT"}},"description":"in Ref. 4; BAD43193","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"D","alternativeSequences":["G"]}}],"keywords":[{"id":"KW-0025","category":"Coding sequence diversity","name":"Alternative splicing"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"11130712","citationType":"journal article","authors":["Theologis A.","Ecker J.R.","Palm C.J.","Federspiel N.A.","Kaul S.","White O.","Alonso J.","Altafi H.","Araujo R.","Bowman C.L.","Brooks S.Y.","Buehler E.","Chan A.","Chao Q.","Chen H.","Cheuk R.F.","Chin C.W.","Chung M.K.","Conn L.","Conway A.B.","Conway A.R.","Creasy T.H.","Dewar K.","Dunn P.","Etgu P.","Feldblyum T.V.","Feng J.-D.","Fong B.","Fujii C.Y.","Gill J.E.","Goldsmith A.D.","Haas B.","Hansen N.F.","Hughes B.","Huizar L.","Hunter J.L.","Jenkins J.","Johnson-Hopson C.","Khan S.","Khaykin E.","Kim C.J.","Koo H.L.","Kremenetskaia I.","Kurtz D.B.","Kwan A.","Lam B.","Langin-Hooper S.","Lee A.","Lee J.M.","Lenz C.A.","Li J.H.","Li Y.-P.","Lin X.","Liu S.X.","Liu Z.A.","Luros J.S.","Maiti R.","Marziali A.","Militscher J.","Miranda M.","Nguyen M.","Nierman W.C.","Osborne B.I.","Pai G.","Peterson J.","Pham P.K.","Rizzo M.","Rooney T.","Rowley D.","Sakano H.","Salzberg S.L.","Schwartz J.R.","Shinn P.","Southwick A.M.","Sun H.","Tallon L.J.","Tambunga G.","Toriumi M.J.","Town C.D.","Utterback T.","Van Aken S.","Vaysberg M.","Vysotskaia V.S.","Walker M.","Wu D.","Yu G.","Fraser C.M.","Venter J.C.","Davis R.W."],"citationCrossReferences":[{"database":"PubMed","id":"11130712"},{"database":"DOI","id":"10.1038/35048500"}],"title":"Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.","publicationDate":"2000","journal":"Nature","firstPage":"816","lastPage":"820","volume":"408"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"27862469","citationType":"journal article","authors":["Cheng C.Y.","Krishnakumar V.","Chan A.P.","Thibaud-Nissen F.","Schobel S.","Town C.D."],"citationCrossReferences":[{"database":"PubMed","id":"27862469"},{"database":"DOI","id":"10.1111/tpj.13415"}],"title":"Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.","publicationDate":"2017","journal":"Plant J.","firstPage":"789","lastPage":"804","volume":"89"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"CI-CI4AM1G71UC0S","citationType":"submission","authoringGroup":["The Arabidopsis Information Resource (TAIR)"],"title":"Community-consensus reference genome of Arabidopsis thaliana Col-0.","publicationDate":"FEB-2026","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"CI-43D7862RKG1IA","citationType":"submission","authors":["Totoki Y.","Seki M.","Ishida J.","Nakajima M.","Enju A.","Kamiya A.","Narusaka M.","Shin-i T.","Nakagawa M.","Sakamoto N.","Oishi K.","Kohara Y.","Kobayashi M.","Toyoda A.","Sakaki Y.","Sakurai T.","Iida K.","Akiyama K.","Satou M.","Toyoda T.","Konagaya A.","Carninci P.","Kawai J.","Hayashizaki Y.","Shinozaki K."],"title":"Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.","publicationDate":"SEP-2004","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"CI-BMBMED9SL03LN","citationType":"submission","authors":["Quinitio C.","Chen H.","Kim C.J.","Shinn P.","Ecker J.R."],"title":"Arabidopsis ORF clones.","publicationDate":"SEP-2006","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AC009324","properties":[{"key":"ProteinId","value":"AAF02862.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002684","properties":[{"key":"ProteinId","value":"AEE33017.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002684","properties":[{"key":"ProteinId","value":"AEE33018.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002684","properties":[{"key":"ProteinId","value":"ANM57833.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002684","properties":[{"key":"ProteinId","value":"ANM57834.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"OZ408683","properties":[{"key":"ProteinId","value":"CAO7030914.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"OZ408683","properties":[{"key":"ProteinId","value":"CAO7030915.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AK175272","properties":[{"key":"ProteinId","value":"BAD43035.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK175430","properties":[{"key":"ProteinId","value":"BAD43193.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AK176711","properties":[{"key":"ProteinId","value":"BAD44474.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"BT028947","properties":[{"key":"ProteinId","value":"ABI49494.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"PIR","id":"H96578","properties":[{"key":"EntryName","value":"H96578"}]},{"database":"RefSeq","id":"NP_001031184.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001036107.3"}],"isoformId":"Q67XV7-2"},{"database":"RefSeq","id":"NP_001319217.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001333617.1"}],"isoformId":"Q67XV7-1"},{"database":"RefSeq","id":"NP_001320314.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001333618.1"}],"isoformId":"Q67XV7-2"},{"database":"RefSeq","id":"NP_564645.1","properties":[{"key":"NucleotideSequenceId","value":"NM_104267.2"}],"isoformId":"Q67XV7-1"},{"database":"AlphaFoldDB","id":"Q67XV7","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q67XV7","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"3702.Q67XV7","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"3702-Q67XV7","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"841827","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ath:AT1G53870","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ath:AT1G53890","properties":[{"key":"Description","value":"-"}]},{"database":"Araport","id":"AT1G53890","properties":[{"key":"Description","value":"-"}]},{"database":"TAIR","id":"AT1G53890","properties":[{"key":"GeneName","value":"-"}]},{"database":"HOGENOM","id":"CLU_063146_2_1_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q67XV7","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"CARKPAY","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"PhylomeDB","id":"Q67XV7","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:Q67XV7","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000006548","properties":[{"key":"Component","value":"Chromosome 1"}]},{"database":"GO","id":"GO:0009507","properties":[{"key":"GoTerm","value":"C:chloroplast"},{"key":"GoEvidenceType","value":"ISM:TAIR"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"ISM:TAIR"}]},{"database":"Gene3D","id":"2.40.160.200","properties":[{"key":"EntryName","value":"LURP1-related"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR007612","properties":[{"key":"EntryName","value":"LOR"}]},{"database":"InterPro","id":"IPR038595","properties":[{"key":"EntryName","value":"LOR_sf"}]},{"database":"InterPro","id":"IPR025659","properties":[{"key":"EntryName","value":"Tubby-like_C"}]},{"database":"PANTHER","id":"PTHR31087","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31087:SF81","properties":[{"key":"EntryName","value":"LURP-ONE-LIKE PROTEIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF04525","properties":[{"key":"EntryName","value":"LOR"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54518","properties":[{"key":"EntryName","value":"Tubby C-terminal domain-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MQIYNPISPVKTMVKIYPHLAFPVDMDVVQDKILPYLTTEQERFTIWMKSLVFNSKGCTVFDSKGNLIYRVDNYDSKSWSNEVYFMDLNGKILFTLRQKKLGFFKSWEGYNSTGTRFRLRKIFKILPRESSSSYKVVMGSRIVDGDQQSCYKIVNRGSVFAIKDGSGRLMAEVKNKLSDISGLDLGDDVLTMMVEPQLDHSLIMGIVIAYKLTKCKL","length":217,"molWeight":24904,"crc64":"A73BC8ABEEA43E03","md5":"2B84AF8A93AB28593EDBE2A5990F5751"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"ALTERNATIVE PRODUCTS":2,"SIMILARITY":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1,"Alternative sequence":2,"Sequence conflict":2},"uniParcId":"UPI000016312C"}}