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The MFS efflux transporter inpD may contribute to fellutamide resistance as well (PubMed:27294372)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"27294372"}],"value":"Secondary metabolite biosynthesis"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"27294372"}],"value":"Greatly diminishes the production of fellutamides (PubMed:27294372)"}],"commentType":"DISRUPTION PHENOTYPE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the LovG family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":437,"modifier":"EXACT"}},"description":"Esterase inpF","featureId":"PRO_0000444113"},{"type":"Region","location":{"start":{"value":306,"modifier":"EXACT"},"end":{"value":362,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":314,"modifier":"EXACT"},"end":{"value":345,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Active site","location":{"start":{"value":112,"modifier":"EXACT"},"end":{"value":112,"modifier":"EXACT"}},"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P38777"}]},{"type":"Active site","location":{"start":{"value":196,"modifier":"EXACT"},"end":{"value":196,"modifier":"EXACT"}},"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P38777"}]},{"type":"Active site","location":{"start":{"value":226,"modifier":"EXACT"},"end":{"value":226,"modifier":"EXACT"}},"description":"Charge relay system","evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"P38777"}]}],"keywords":[{"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"16372000","citationType":"journal article","authors":["Galagan J.E.","Calvo S.E.","Cuomo C.","Ma L.-J.","Wortman J.R.","Batzoglou S.","Lee S.-I.","Bastuerkmen M.","Spevak C.C.","Clutterbuck J.","Kapitonov V.","Jurka J.","Scazzocchio C.","Farman M.L.","Butler J.","Purcell S.","Harris S.","Braus G.H.","Draht O.","Busch S.","D'Enfert C.","Bouchier C.","Goldman G.H.","Bell-Pedersen D.","Griffiths-Jones S.","Doonan J.H.","Yu J.","Vienken K.","Pain A.","Freitag M.","Selker E.U.","Archer D.B.","Penalva M.A.","Oakley B.R.","Momany M.","Tanaka T.","Kumagai T.","Asai K.","Machida M.","Nierman W.C.","Denning D.W.","Caddick M.X.","Hynes M.","Paoletti M.","Fischer R.","Miller B.L.","Dyer P.S.","Sachs M.S.","Osmani S.A.","Birren B.W."],"citationCrossReferences":[{"database":"PubMed","id":"16372000"},{"database":"DOI","id":"10.1038/nature04341"}],"title":"Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.","publicationDate":"2005","journal":"Nature","firstPage":"1105","lastPage":"1115","volume":"438"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"19146970","citationType":"journal article","authors":["Wortman J.R.","Gilsenan J.M.","Joardar V.","Deegan J.","Clutterbuck J.","Andersen M.R.","Archer D.","Bencina M.","Braus G.","Coutinho P.","von Dohren H.","Doonan J.","Driessen A.J.","Durek P.","Espeso E.","Fekete E.","Flipphi M.","Estrada C.G.","Geysens S.","Goldman G.","de Groot P.W.","Hansen K.","Harris S.D.","Heinekamp T.","Helmstaedt K.","Henrissat B.","Hofmann G.","Homan T.","Horio T.","Horiuchi H.","James S.","Jones M.","Karaffa L.","Karanyi Z.","Kato M.","Keller N.","Kelly D.E.","Kiel J.A.","Kim J.M.","van der Klei I.J.","Klis F.M.","Kovalchuk A.","Krasevec N.","Kubicek C.P.","Liu B.","Maccabe A.","Meyer V.","Mirabito P.","Miskei M.","Mos M.","Mullins J.","Nelson D.R.","Nielsen J.","Oakley B.R.","Osmani S.A.","Pakula T.","Paszewski A.","Paulsen I.","Pilsyk S.","Pocsi I.","Punt P.J.","Ram A.F.","Ren Q.","Robellet X.","Robson G.","Seiboth B.","van Solingen P.","Specht T.","Sun J.","Taheri-Talesh N.","Takeshita N.","Ussery D.","vanKuyk P.A.","Visser H.","van de Vondervoort P.J.","de Vries R.P.","Walton J.","Xiang X.","Xiong Y.","Zeng A.P.","Brandt B.W.","Cornell M.J.","van den Hondel C.A.","Visser J.","Oliver S.G.","Turner G."],"citationCrossReferences":[{"database":"PubMed","id":"19146970"},{"database":"DOI","id":"10.1016/j.fgb.2008.12.003"}],"title":"The 2008 update of the Aspergillus nidulans genome annotation: a community effort.","publicationDate":"2009","journal":"Fungal Genet. 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