{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q58838","uniProtkbId":"Y1443_METJA","entryAudit":{"firstPublicDate":"2000-12-01","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"1996-11-01","entryVersion":102,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","commonName":"Methanococcus jannaschii","taxonId":243232,"lineage":["Archaea","Methanobacteriati","Methanobacteriota","Methanomada group","Methanococci","Methanococcales","Methanocaldococcaceae","Methanocaldococcus"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"UPF0132 membrane protein MJ1443"}}},"genes":[{"orderedLocusNames":[{"value":"MJ1443"}]}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the UPF0132 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":110,"modifier":"EXACT"}},"description":"UPF0132 membrane protein MJ1443","featureId":"PRO_0000158602"},{"type":"Transmembrane","location":{"start":{"value":15,"modifier":"EXACT"},"end":{"value":35,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":49,"modifier":"EXACT"},"end":{"value":69,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":70,"modifier":"EXACT"},"end":{"value":90,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}],"keywords":[{"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"8688087","citationType":"journal article","authors":["Bult C.J.","White O.","Olsen G.J.","Zhou L.","Fleischmann R.D.","Sutton G.G.","Blake J.A.","FitzGerald L.M.","Clayton R.A.","Gocayne J.D.","Kerlavage A.R.","Dougherty B.A.","Tomb J.-F.","Adams M.D.","Reich C.I.","Overbeek R.","Kirkness E.F.","Weinstock K.G.","Merrick J.M.","Glodek A.","Scott J.L.","Geoghagen N.S.M.","Weidman J.F.","Fuhrmann J.L.","Nguyen D.","Utterback T.R.","Kelley J.M.","Peterson J.D.","Sadow P.W.","Hanna M.C.","Cotton M.D.","Roberts K.M.","Hurst M.A.","Kaine B.P.","Borodovsky M.","Klenk H.-P.","Fraser C.M.","Smith H.O.","Woese C.R.","Venter J.C."],"citationCrossReferences":[{"database":"PubMed","id":"8688087"},{"database":"DOI","id":"10.1126/science.273.5278.1058"}],"title":"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.","publicationDate":"1996","journal":"Science","firstPage":"1058","lastPage":"1073","volume":"273"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"L77117","properties":[{"key":"ProteinId","value":"AAB99453.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"B64480","properties":[{"key":"EntryName","value":"B64480"}]},{"database":"AlphaFoldDB","id":"Q58838","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q58838","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"243232.MJ_1443","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"243232-MJ_1443","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"AAB99453","properties":[{"key":"ProteinId","value":"AAB99453"},{"key":"GeneId","value":"MJ_1443"}]},{"database":"KEGG","id":"mja:MJ_1443","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"arCOG04344","properties":[{"key":"ToxonomicScope","value":"Archaea"}]},{"database":"HOGENOM","id":"CLU_095018_3_0_2","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q58838","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"329551at2157","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q58838","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000805","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"InterPro","id":"IPR019109","properties":[{"key":"EntryName","value":"MamF_MmsF"}]},{"database":"PANTHER","id":"PTHR36460","properties":[{"key":"EntryName","value":"UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR36460:SF1","properties":[{"key":"EntryName","value":"UPF0132 DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_3G10255)"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF09685","properties":[{"key":"EntryName","value":"MamF_MmsF"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MIFMGKTSLGLDENIEGALCYLFGVITGILFYILEKESKFVKFHAVQSIILFGGLWVLSIILAFIPYGWMLSGLVNLAAFILWIVCMYKAYKGEKFKLPVIGDIAEQYSQ","length":110,"molWeight":12411,"crc64":"0D162443D7741796","md5":"689BE500154FCBFD663369CB7B77E527"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Transmembrane":3},"uniParcId":"UPI000013AADB"}}