{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q57607","uniProtkbId":"Y142_METJA","entryAudit":{"firstPublicDate":"1997-11-01","lastAnnotationUpdateDate":"2025-02-05","lastSequenceUpdateDate":"1998-12-15","entryVersion":89,"sequenceVersion":2},"annotationScore":1.0,"organism":{"scientificName":"Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)","commonName":"Methanococcus jannaschii","taxonId":243232,"lineage":["Archaea","Methanobacteriati","Methanobacteriota","Methanomada group","Methanococci","Methanococcales","Methanocaldococcaceae","Methanocaldococcus"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"Putative toxin MJ0142"}},"alternativeNames":[{"fullName":{"value":"UPF0332 protein MJ0142"}}]},"genes":[{"orderedLocusNames":[{"value":"MJ0142"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Putative toxin component of a putative type VII toxin-antitoxin (TA) system. Its cognate antitoxin might be MJ0141"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the UPF0332 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":147,"modifier":"EXACT"}},"description":"Putative toxin MJ0142","featureId":"PRO_0000159639"}],"keywords":[{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-1277","category":"Biological process","name":"Toxin-antitoxin system"}],"references":[{"referenceNumber":1,"citation":{"id":"8688087","citationType":"journal article","authors":["Bult C.J.","White O.","Olsen G.J.","Zhou L.","Fleischmann R.D.","Sutton G.G.","Blake J.A.","FitzGerald L.M.","Clayton R.A.","Gocayne J.D.","Kerlavage A.R.","Dougherty B.A.","Tomb J.-F.","Adams M.D.","Reich C.I.","Overbeek R.","Kirkness E.F.","Weinstock K.G.","Merrick J.M.","Glodek A.","Scott J.L.","Geoghagen N.S.M.","Weidman J.F.","Fuhrmann J.L.","Nguyen D.","Utterback T.R.","Kelley J.M.","Peterson J.D.","Sadow P.W.","Hanna M.C.","Cotton M.D.","Roberts K.M.","Hurst M.A.","Kaine B.P.","Borodovsky M.","Klenk H.-P.","Fraser C.M.","Smith H.O.","Woese C.R.","Venter J.C."],"citationCrossReferences":[{"database":"PubMed","id":"8688087"},{"database":"DOI","id":"10.1126/science.273.5278.1058"}],"title":"Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.","publicationDate":"1996","journal":"Science","firstPage":"1058","lastPage":"1073","volume":"273"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"L77117","properties":[{"key":"ProteinId","value":"AAB98125.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"G64317","properties":[{"key":"EntryName","value":"G64317"}]},{"database":"AlphaFoldDB","id":"Q57607","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q57607","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"243232.MJ_0142","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"243232-MJ_0142","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"AAB98125","properties":[{"key":"ProteinId","value":"AAB98125"},{"key":"GeneId","value":"MJ_0142"}]},{"database":"KEGG","id":"mja:MJ_0142","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"arCOG02123","properties":[{"key":"ToxonomicScope","value":"Archaea"}]},{"database":"HOGENOM","id":"CLU_151247_1_0_2","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q57607","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"101012at2157","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"Q57607","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000805","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"Gene3D","id":"1.20.120.330","properties":[{"key":"EntryName","value":"Nucleotidyltransferases domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR007842","properties":[{"key":"EntryName","value":"HEPN_dom"}]},{"database":"InterPro","id":"IPR052226","properties":[{"key":"EntryName","value":"UPF0332_toxin"}]},{"database":"PANTHER","id":"PTHR36565","properties":[{"key":"EntryName","value":"UPF0332 PROTEIN TM_1000"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR36565:SF1","properties":[{"key":"EntryName","value":"UPF0332 PROTEIN TM_1000"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF05168","properties":[{"key":"EntryName","value":"HEPN"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF81593","properties":[{"key":"EntryName","value":"Nucleotidyltransferase substrate binding subunit/domain"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MRLKIMELRYKRELEKLIEKAEKSLEASENLYNSEFYDFAVSRIYYSMFYCVKALLLTKEINPKKHSGVLKMFAKEFIKTNELDVELFEYINEAYNYRQTADYDATIEIKKEEAEYLLHKGHIFLNKTKKYLISKNILKGENDNTKS","length":147,"molWeight":17592,"crc64":"707D67BF058E065C","md5":"47F41F8F32D3D6D5F8375A5C2F448279"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI0000139353"}}