{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q3I5I9","uniProtkbId":"NS7B_BCRP3","entryAudit":{"firstPublicDate":"2005-11-22","lastAnnotationUpdateDate":"2026-06-10","lastSequenceUpdateDate":"2005-11-08","entryVersion":50,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Bat coronavirus Rp3/2004","commonName":"BtCoV/Rp3/2004","synonyms":["SARS-like coronavirus Rp3"],"taxonId":349344,"lineage":["Viruses","Riboviria","Orthornavirae","Pisuviricota","Pisoniviricetes","Nidovirales","Cornidovirineae","Coronaviridae","Orthocoronavirinae","Betacoronavirus","Sarbecovirus","Betacoronavirus pandemicum","Severe acute respiratory syndrome coronavirus"]},"organismHosts":[{"scientificName":"Rhinolophus ferrumequinum","commonName":"Greater horseshoe bat","taxonId":59479},{"scientificName":"Rhinolophus macrotis","commonName":"Big-eared horseshoe bat","taxonId":196889},{"scientificName":"Rhinolophus pearsonii","taxonId":188571},{"scientificName":"Rhinolophus sinicus","commonName":"Chinese rufous horseshoe bat","taxonId":89399}],"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"value":"Non-structural protein 7b"},"shortNames":[{"value":"ns7b"}]},"alternativeNames":[{"fullName":{"value":"Accessory protein 7b"}}]},"genes":[{"orfNames":[{"value":"7b"}]}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Host membrane","id":"SL-0380"},"topology":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Single-pass membrane protein","id":"SL-9904"}}]},{"texts":[{"value":"Bat coronavirus rp3 is highly similar to SARS-CoV (SARS-like)"}],"commentType":"MISCELLANEOUS"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":44,"modifier":"EXACT"}},"description":"Non-structural protein 7b","featureId":"PRO_0000106138"},{"type":"Transmembrane","location":{"start":{"value":9,"modifier":"EXACT"},"end":{"value":29,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}],"keywords":[{"id":"KW-1043","category":"Cellular component","name":"Host membrane"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"16195424","citationType":"journal article","authors":["Li W.","Shi Z.","Yu M.","Ren W.","Smith C.","Epstein J.H.","Wang H.","Crameri G.","Hu Z.","Zhang H.","Zhang J.","McEachern J.","Field H.","Daszak P.","Eaton B.T.","Zhang S.","Wang L.F."],"citationCrossReferences":[{"database":"PubMed","id":"16195424"},{"database":"DOI","id":"10.1126/science.1118391"}],"title":"Bats are natural reservoirs of SARS-like coronaviruses.","publicationDate":"2005","journal":"Science","firstPage":"676","lastPage":"679","volume":"310"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC RNA]"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"DQ071615","properties":[{"key":"ProteinId","value":"AAZ67058.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_RNA"}]},{"database":"SMR","id":"Q3I5I9","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0033644","properties":[{"key":"GoTerm","value":"C:host cell membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd21635","properties":[{"key":"EntryName","value":"ORF7b_SARS-CoV-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR021532","properties":[{"key":"EntryName","value":"NS7B_bCoV"}]},{"database":"InterPro","id":"IPR044394","properties":[{"key":"EntryName","value":"ORF7b_SARS-CoV-like"}]},{"database":"Pfam","id":"PF11395","properties":[{"key":"EntryName","value":"bCoV_NS7B"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MNELTLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDIEEPCNKV","length":44,"molWeight":5315,"crc64":"3BD65678E311E048","md5":"396E274CB6687A1940814088229D2F0A"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"MISCELLANEOUS":1},"countByFeatureType":{"Chain":1,"Transmembrane":1},"uniParcId":"UPI00005C4E5A"}}