{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q39079","secondaryAccessions":["Q9SL89"],"uniProtkbId":"DNJ13_ARATH","entryAudit":{"firstPublicDate":"2005-05-10","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2005-05-10","entryVersion":145,"sequenceVersion":2},"annotationScore":4.0,"organism":{"scientificName":"Arabidopsis thaliana","commonName":"Mouse-ear cress","taxonId":3702,"lineage":["Eukaryota","Viridiplantae","Streptophyta","Embryophyta","Tracheophyta","Spermatophyta","Magnoliopsida","eudicotyledons","Gunneridae","Pentapetalae","rosids","malvids","Brassicales","Brassicaceae","Camelineae","Arabidopsis"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Chaperone protein dnaJ 13"},"shortNames":[{"value":"AtDjB13"},{"value":"AtJ13"}]}},"genes":[{"geneName":{"value":"ATJ13"},"synonyms":[{"value":"B13"},{"value":"D3"}],"orderedLocusNames":[{"value":"At2g35720"}],"orfNames":[{"value":"T20F21.9"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"7479844"}],"value":"Plays a continuous role in plant development probably in the structural organization of compartments (By similarity). Seems to be involved in resistance to oxidative stresses mediated by thiol-oxidizing agents such as diamide"}],"commentType":"FUNCTION"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q39079","intActId":"EBI-2461966"},"interactantTwo":{"uniProtKBAccession":"Q9FE22","geneName":"HFR1","intActId":"EBI-626001"},"numberOfExperiments":3,"organismDiffer":false}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Membrane","id":"SL-0162"},"topology":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Single-pass membrane protein","id":"SL-9904"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"7479844"}],"value":"Constitutively expressed in roots, stems, leaves and flowers"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"7479844"}],"value":"Not induced by methyl viologen (paraquat), menadione, diamide, t-BuOOH, dithiothreitol (DTT) and H(2)O(2)"}],"commentType":"INDUCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the DnaJ family. B/II subfamily"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"AAD15443.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":538,"modifier":"EXACT"}},"description":"Chaperone protein dnaJ 13","featureId":"PRO_0000071082"},{"type":"Transmembrane","location":{"start":{"value":354,"modifier":"EXACT"},"end":{"value":374,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Domain","location":{"start":{"value":15,"modifier":"EXACT"},"end":{"value":83,"modifier":"EXACT"}},"description":"J","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00286"}]},{"type":"Coiled coil","location":{"start":{"value":96,"modifier":"EXACT"},"end":{"value":124,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Modified residue","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1,"modifier":"EXACT"}},"description":"N-acetylmethionine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"22223895"}]},{"type":"Sequence conflict","location":{"start":{"value":459,"modifier":"EXACT"},"end":{"value":459,"modifier":"EXACT"}},"description":"in Ref. 1; CAA89204","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"E","alternativeSequences":["EE"]}}],"keywords":[{"id":"KW-0007","category":"PTM","name":"Acetylation"},{"id":"KW-0143","category":"Molecular function","name":"Chaperone"},{"id":"KW-0175","category":"Domain","name":"Coiled coil"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"7479844","citationType":"journal article","authors":["Kushnir S.","Babiychuk E.","Kampfenkel K.","Belles-Boix E.","Van Montagu M.","Inze D."],"citationCrossReferences":[{"database":"PubMed","id":"7479844"},{"database":"DOI","id":"10.1073/pnas.92.23.10580"}],"title":"Characterization of Arabidopsis thaliana cDNAs that render yeasts tolerant toward the thiol-oxidizing drug diamide.","publicationDate":"1995","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"10580","lastPage":"10584","volume":"92"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA]","FUNCTION","TISSUE SPECIFICITY","INDUCTION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"},{"value":"Leaf","type":"TISSUE"}]},{"referenceNumber":2,"citation":{"id":"10617197","citationType":"journal article","authors":["Lin X.","Kaul S.","Rounsley S.D.","Shea T.P.","Benito M.-I.","Town C.D.","Fujii C.Y.","Mason T.M.","Bowman C.L.","Barnstead M.E.","Feldblyum T.V.","Buell C.R.","Ketchum K.A.","Lee J.J.","Ronning C.M.","Koo H.L.","Moffat K.S.","Cronin L.A.","Shen M.","Pai G.","Van Aken S.","Umayam L.","Tallon L.J.","Gill J.E.","Adams M.D.","Carrera A.J.","Creasy T.H.","Goodman H.M.","Somerville C.R.","Copenhaver G.P.","Preuss D.","Nierman W.C.","White O.","Eisen J.A.","Salzberg S.L.","Fraser C.M.","Venter J.C."],"citationCrossReferences":[{"database":"PubMed","id":"10617197"},{"database":"DOI","id":"10.1038/45471"}],"title":"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.","publicationDate":"1999","journal":"Nature","firstPage":"761","lastPage":"768","volume":"402"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"27862469","citationType":"journal article","authors":["Cheng C.Y.","Krishnakumar V.","Chan A.P.","Thibaud-Nissen F.","Schobel S.","Town C.D."],"citationCrossReferences":[{"database":"PubMed","id":"27862469"},{"database":"DOI","id":"10.1111/tpj.13415"}],"title":"Araport11: a complete reannotation of the Arabidopsis thaliana reference genome.","publicationDate":"2017","journal":"Plant J.","firstPage":"789","lastPage":"804","volume":"89"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"CI-CI4AM1G71UC0S","citationType":"submission","authoringGroup":["The Arabidopsis Information Resource (TAIR)"],"title":"Community-consensus reference genome of Arabidopsis thaliana Col-0.","publicationDate":"FEB-2026","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"cv. Columbia","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"11599562","citationType":"journal article","authors":["Miernyk J.A."],"citationCrossReferences":[{"database":"PubMed","id":"11599562"},{"database":"DOI","id":"10.1379/1466-1268(2001)006<0209:tjdpoa>2.0.co;2"}],"title":"The J-domain proteins of Arabidopsis thaliana: an unexpectedly large and diverse family of chaperones.","publicationDate":"2001","journal":"Cell Stress Chaperones","firstPage":"209","lastPage":"218","volume":"6"},"referencePositions":["GENE FAMILY","NOMENCLATURE"]},{"referenceNumber":6,"citation":{"id":"22223895","citationType":"journal article","authors":["Bienvenut W.V.","Sumpton D.","Martinez A.","Lilla S.","Espagne C.","Meinnel T.","Giglione C."],"citationCrossReferences":[{"database":"PubMed","id":"22223895"},{"database":"DOI","id":"10.1074/mcp.m111.015131"}],"title":"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.","publicationDate":"2012","journal":"Mol. Cell. Proteomics","firstPage":"M111.015131","lastPage":"M111.015131","volume":"11"},"referencePositions":["ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"Z49238","properties":[{"key":"ProteinId","value":"CAA89204.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"AC006068","properties":[{"key":"ProteinId","value":"AAD15443.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"CP002685","properties":[{"key":"ProteinId","value":"AEC09150.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"OZ408684","properties":[{"key":"ProteinId","value":"CAO7037586.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"B84772","properties":[{"key":"EntryName","value":"B84772"}]},{"database":"PIR","id":"S58287","properties":[{"key":"EntryName","value":"S58287"}]},{"database":"AlphaFoldDB","id":"Q39079","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q39079","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"Q39079","properties":[{"key":"Number of interactors","value":"4013"}]},{"database":"IntAct","id":"Q39079","properties":[{"key":"Interactions","value":"1"}]},{"database":"STRING","id":"3702.Q39079","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"Q39079","properties":[{"key":"glycosylation","value":"1 site"}]},{"database":"iPTMnet","id":"Q39079","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"3702-Q39079","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"222079","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"818142","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ath:AT2G35720","properties":[{"key":"Description","value":"-"}]},{"database":"Araport","id":"AT2G35720","properties":[{"key":"Description","value":"-"}]},{"database":"TAIR","id":"AT2G35720","properties":[{"key":"GeneName","value":"OWL1"}]},{"database":"eggNOG","id":"KOG0718","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_019611_0_1_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q39079","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"QLDKHTM","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"PhylomeDB","id":"Q39079","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:Q39079","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000006548","properties":[{"key":"Component","value":"Chromosome 2"}]},{"database":"GO","id":"GO:0009507","properties":[{"key":"GoTerm","value":"C:chloroplast"},{"key":"GoEvidenceType","value":"ISM:TAIR"}]},{"database":"GO","id":"GO:0005783","properties":[{"key":"GoTerm","value":"C:endoplasmic reticulum"},{"key":"GoEvidenceType","value":"HDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"28887381"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0009536","properties":[{"key":"GoTerm","value":"C:plastid"},{"key":"GoEvidenceType","value":"HDA:TAIR"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"22923678"}]},{"database":"GO","id":"GO:0055122","properties":[{"key":"GoTerm","value":"P:response to very low light intensity stimulus"},{"key":"GoEvidenceType","value":"IMP:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"19808946"}]},{"database":"GO","id":"GO:0010228","properties":[{"key":"GoTerm","value":"P:vegetative to reproductive phase transition of meristem"},{"key":"GoEvidenceType","value":"IMP:TAIR"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"19808946"}]},{"database":"CDD","id":"cd06257","properties":[{"key":"EntryName","value":"DnaJ"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.287.110","properties":[{"key":"EntryName","value":"DnaJ domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR042162","properties":[{"key":"EntryName","value":"AtJ13"}]},{"database":"InterPro","id":"IPR024586","properties":[{"key":"EntryName","value":"DnaJ-like_C11_C"}]},{"database":"InterPro","id":"IPR001623","properties":[{"key":"EntryName","value":"DnaJ_domain"}]},{"database":"InterPro","id":"IPR018253","properties":[{"key":"EntryName","value":"DnaJ_domain_CS"}]},{"database":"InterPro","id":"IPR055225","properties":[{"key":"EntryName","value":"DNAJC11-like_beta-barrel"}]},{"database":"InterPro","id":"IPR036869","properties":[{"key":"EntryName","value":"J_dom_sf"}]},{"database":"PANTHER","id":"PTHR44914","properties":[{"key":"EntryName","value":"CHAPERONE PROTEIN DNAJ 13"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR44914:SF1","properties":[{"key":"EntryName","value":"CHAPERONE PROTEIN DNAJ 13"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00226","properties":[{"key":"EntryName","value":"DnaJ"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF11875","properties":[{"key":"EntryName","value":"DnaJ-like_C11_C"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF22774","properties":[{"key":"EntryName","value":"DNAJC11_beta-barrel"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00625","properties":[{"key":"EntryName","value":"JDOMAIN"}]},{"database":"SMART","id":"SM00271","properties":[{"key":"EntryName","value":"DnaJ"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46565","properties":[{"key":"EntryName","value":"Chaperone J-domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00636","properties":[{"key":"EntryName","value":"DNAJ_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS50076","properties":[{"key":"EntryName","value":"DNAJ_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MMGQEAAPTGPPNRELYALLNLSPEASDEEIRKAYRQWAQVYHPDKIQSPQMKEVATENFQRICEAYEILSDETKRLIYDLYGMEGLNSGLELGPRLSKADEIKEELERIKRRNEEAKKMAHFQPTGSILFNLSVPHFLVGDGIMRGMVMASQVQSQLSKDDAIAIGGNLAANEKSGGGVATAILRRQISPVSSIEFVASTGLQSLIGVQTTRQLTIHSTATINISKSLSDGSINLTNTWTRQLSETSSGNIELALGMRSAITVGWKKRDENVSAAGDFKIESGGLGASARYTRKLSSKSHGRIVGRIGSNALEIELGGGRQISEFSTVRMMYTVGLKGIFWKVELHRGSQKLIVPILLSAHLAPVFATGAFIVPTSLYFLLKKFVVKPYLLKREKQKALENMEKTWGQVGEARARAEKAQQLLQTVATRKKNRQVETDGLIVTKALYGDPKAIERRNEGVEGLDSGVIDVTVPMNFLVSDSGQLKLHEGVKKSGIMGFCDPCPGQPKQLYIAYTYHSQPFEVIVGDYEELSIPQEGQ","length":538,"molWeight":59232,"crc64":"7DFCB509E216AC76","md5":"3F8A586066F610E908753AB181A7F7E6"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"INTERACTION":1,"SUBCELLULAR LOCATION":1,"TISSUE SPECIFICITY":1,"INDUCTION":1,"SIMILARITY":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1,"Transmembrane":1,"Domain":1,"Coiled coil":1,"Modified residue":1,"Sequence conflict":1},"uniParcId":"UPI0000196DA6"}}