{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q2T9M9","uniProtkbId":"JHY_BOVIN","entryAudit":{"firstPublicDate":"2007-03-20","lastAnnotationUpdateDate":"2026-06-10","lastSequenceUpdateDate":"2006-01-24","entryVersion":63,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Bos taurus","commonName":"Bovine","taxonId":9913,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Laurasiatheria","Artiodactyla","Ruminantia","Pecora","Bovidae","Bovinae","Bos"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"value":"Jhy protein homolog"}}},"genes":[{"geneName":{"value":"JHY"}}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250","source":"UniProtKB","id":"E9Q793"}],"value":"Required for the normal development of cilia in brain ependymal cells lining the ventricular surfaces"}],"commentType":"FUNCTION"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":773,"modifier":"EXACT"}},"description":"Jhy protein homolog","featureId":"PRO_0000281675"},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":247,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":325,"modifier":"EXACT"},"end":{"value":373,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":496,"modifier":"EXACT"},"end":{"value":526,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":596,"modifier":"EXACT"},"end":{"value":615,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":713,"modifier":"EXACT"},"end":{"value":743,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":10,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":29,"modifier":"EXACT"},"end":{"value":43,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":48,"modifier":"EXACT"},"end":{"value":57,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":59,"modifier":"EXACT"},"end":{"value":84,"modifier":"EXACT"}},"description":"Acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":112,"modifier":"EXACT"},"end":{"value":134,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":145,"modifier":"EXACT"},"end":{"value":154,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":216,"modifier":"EXACT"},"end":{"value":229,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":334,"modifier":"EXACT"},"end":{"value":351,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":353,"modifier":"EXACT"},"end":{"value":369,"modifier":"EXACT"}},"description":"Basic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":500,"modifier":"EXACT"},"end":{"value":516,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":598,"modifier":"EXACT"},"end":{"value":610,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":728,"modifier":"EXACT"},"end":{"value":743,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-0970","category":"Biological process","name":"Cilium biogenesis/degradation"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-BB3IDDUPNB5P2","citationType":"submission","authoringGroup":["NIH - Mammalian Gene Collection (MGC) project"],"publicationDate":"DEC-2005","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Crossbred X Angus","type":"STRAIN"},{"value":"Liver","type":"TISSUE"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"BC111348","properties":[{"key":"ProteinId","value":"AAI11349.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"RefSeq","id":"NP_001033297.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001038208.1"}]},{"database":"AlphaFoldDB","id":"Q2T9M9","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q2T9M9","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"Q2T9M9","properties":[{"key":"Number of interactors","value":"25"}]},{"database":"STRING","id":"9913.ENSBTAP00000047568","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9913-ENSBTAP00000047568","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"615337","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"bta:615337","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"79864","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q2T9M9","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"10057281at2759","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000009136","properties":[{"key":"Component","value":"Unplaced"}]},{"database":"GO","id":"GO:0035082","properties":[{"key":"GoTerm","value":"P:axoneme assembly"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0007420","properties":[{"key":"GoTerm","value":"P:brain development"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"InterPro","id":"IPR027968","properties":[{"key":"EntryName","value":"JHY"}]},{"database":"PANTHER","id":"PTHR14726","properties":[{"key":"EntryName","value":"JHY PROTEIN HOMOLOG"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR14726:SF1","properties":[{"key":"EntryName","value":"JHY PROTEIN HOMOLOG"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF15261","properties":[{"key":"EntryName","value":"JHY"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSHSKFIPTVSIQSPVHHTNIKVQSTEPSFKKEDLHLISKDSLESDSESPTQKIKSQSDLEDQIQDNDMEPDSLEEENLSETEEEASRKAAQRAKKENLHTQDAAAINSRQPTEDKYSHIRYDPNWKSKKEEGKLLPVEALPESVDSSTENLTLNPLYPSKEPSMDLSAGKGEQKSPRSTASLLGSEFVSPNYELSTHRTEPFSVLSDSDPEEKSSNLSRYLKSSSSRSEAFLPGSRGPRRRKSKQYFVEKNKLTLGLPTPRMDSYLQLHNKKRGEGHLEQISYPVRVTDKTSIQNARETGNVAIDPEDKWHQRAQQLKDYQEHWSQYEHEKSSSGPRGQSSETTNGQQPSRKPAKHKIRKQRRHRHGPKSLVTEELVVSQGNQNNTPRHQQNPNKPIDTEVTQETVVIMNATNDDLQYSSVLRSQDPTVTSNQYAPLHQISDKVLYKNPARYYPVTNANRERGHNDQEEKRFSYQQLHIDTLSDMHLNYLHELNKKHPSGSQKGSQSVSNINRQASTEKKKQPKLAYTETKYKNLEILWKFHSSSEEQPAKASPDSRLSQIMEQHQQALLQLTEVQPHEGASPGLTLPPILPRVESESQLSSERSQRNQVKISRSNSESYLFQLEKGKKHRKRSSIKSSKLKGYQNRDVKLGGLGPDLESIRDKMQKLIQQKEYAKQVKEYNMKALSIPSKPQTAITENKSAVPRQKALEYAKTIPKPKPSNLSDQASKEKKTPTHAGKEDTLPEISLLEVLQNRHEREKQAVAAFKVLHIV","length":773,"molWeight":87993,"crc64":"746FFFC10693F8D1","md5":"05840B5F0CC941C3F1CE5B83A8834D7B"},"extraAttributes":{"countByCommentType":{"FUNCTION":1},"countByFeatureType":{"Chain":1,"Region":5,"Compositional bias":12},"uniParcId":"UPI0000663915"}}