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Positively regulates the accumulation of the CCR4-NOT complex component ccr-1 (PubMed:23843623). Within the complex promotes germ cell development and fertility in hermaphrodites (PubMed:23843623). Additional complex functions may be a consequence of its influence on mRNA expression (By similarity). Its scaffolding function implies its interaction with the catalytic complex module and diverse RNA-binding proteins mediating the complex recruitment to selected mRNA 3'UTRs (By similarity). Mediates the recruitment of the CCR4-NOT complex to miRNA targets and to the RISC complex (Probable). Acts as a transcriptional repressor (By similarity). Represses the ligand-dependent transcriptional activation by nuclear receptors (By similarity). In embryos, plays a role in female pronucleus and mitotic spindle positioning during the first cleavage divisions after fertilization (PubMed:16971515). This may partly be through negatively regulating the accumulation of zyg-9 at the centrosome (PubMed:16971515). Negatively regulates the formation of long astral microtubules in developing embryos (PubMed:16971515). Required for the stabilization and degradation of maternal mRNAs such as nos-2 in somatic blastomeres (PubMed:18692039)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23843623"}],"value":"Component of the CCR4-NOT complex at least composed of ccf-1, ccr-4 and let-711, which is required for germ cell development in hermaphrodites (PubMed:23843623). 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RNAi-mediated knockdown may also result in a reduced brood size and larval lethality (PubMed:23843623). RNAi-mediated knockdown disrupts the arrangement and differentiation of oocytes in the proximal region and as a result small oocyte-like cells arrange in several rows in the germline (PubMed:23843623). RNAi-mediated knockdown reduces the levels of ccf-1, but does not alter ccr-4 levels (PubMed:23843623). RNAi-mediated knockdown results in reduced global poly(A) tail deadenylation (PubMed:23843623). RNAi-mediated knockdown results in reduces degradation of nos-2 mRNA, impairs the recruitment of lsm-1 and decreases the number of patr-1-positive granules in somatic blastomeres (PubMed:18692039)"}],"commentType":"DISRUPTION PHENOTYPE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the CNOT1 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":2641,"modifier":"EXACT"}},"description":"CCR4-NOT transcription complex subunit 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