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IR-HR is a DNA repair mechanism where a cell repairs a DSB on one chromosome using the matching homologous chromosome as a template, rather than the sister chromatid (PubMed:34253720)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23509288"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"23754376"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"39169038"}],"value":"Found in a complex, at least composed of BLM, RAD51 and SPIDR; the complex formation is mediated by SPIDR (PubMed:23509288). Interacts (via C-terminal region) with BLM; the interaction is direct (PubMed:23509288). Interacts with RAD51; the interaction is direct (PubMed:23509288). Interacts (via the C-terminal region) with FIGNL1 (via N-terminal one-half region); the interaction is direct (PubMed:23754376). 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