{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"Q05DH4","secondaryAccessions":["Q6ZUS2"],"uniProtkbId":"FHI1A_HUMAN","entryAudit":{"firstPublicDate":"2008-02-26","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-02-26","entryVersion":120,"sequenceVersion":2},"annotationScore":4.0,"organism":{"scientificName":"Homo sapiens","commonName":"Human","taxonId":9606,"lineage":["Eukaryota","Metazoa","Chordata","Craniata","Vertebrata","Euteleostomi","Mammalia","Eutheria","Euarchontoglires","Primates","Haplorrhini","Catarrhini","Hominidae","Homo"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"FHF complex subunit HOOK-interacting protein 1A"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"FHIP1A"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"32073997"}],"value":"FTS- and Hook-interacting protein like"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"32073997"}],"value":"FHIP-L"}]}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000312","source":"HGNC","id":"HGNC:34237"}],"value":"FHIP1A"},"synonyms":[{"value":"FAM160A1"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"32073997"}],"value":"Probable component of the FTS/Hook/FHIP complex (FHF complex) (PubMed:32073997). FHF complex promotes the distribution of AP-4 complex to the perinuclear area of the cell (PubMed:32073997)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"32073997"}],"value":"May be a component of the FTS/Hook/FHIP complex (FHF complex), composed of AKTIP/FTS, FHIP1B, and one or more members of the Hook family of proteins HOOK1, HOOK2, and HOOK3. May interact directly with AKTIP/FTS"}],"commentType":"SUBUNIT"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"Q05DH4","intActId":"EBI-21303726"},"interactantTwo":{"uniProtKBAccession":"Q9H8T0","geneName":"AKTIP","intActId":"EBI-711399"},"numberOfExperiments":5,"organismDiffer":false}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the FHIP family"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"AAH14937.1","note":"Truncated N-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Miscellaneous discrepancy","sequence":"AAH14937.1","note":"Contaminating sequence. Potential poly-A sequence.","evidences":[{"evidenceCode":"ECO:0000305"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Frameshift","sequence":"BAC86147.1","evidences":[{"evidenceCode":"ECO:0000305"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Miscellaneous discrepancy","sequence":"BAC86147.1","note":"Aberrant splicing.","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":1040,"modifier":"EXACT"}},"description":"FHF complex subunit HOOK-interacting protein 1A","featureId":"PRO_0000319578"},{"type":"Region","location":{"start":{"value":555,"modifier":"EXACT"},"end":{"value":613,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":653,"modifier":"EXACT"},"end":{"value":746,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":769,"modifier":"EXACT"},"end":{"value":808,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":653,"modifier":"EXACT"},"end":{"value":664,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":677,"modifier":"EXACT"},"end":{"value":690,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":696,"modifier":"EXACT"},"end":{"value":719,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":783,"modifier":"EXACT"},"end":{"value":804,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Natural variant","location":{"start":{"value":943,"modifier":"EXACT"},"end":{"value":943,"modifier":"EXACT"}},"description":"found in siblings with familial natural-killer/T-cell lymphoma; uncertain significance","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"30420729"}],"featureId":"VAR_084431","alternativeSequence":{"originalSequence":"R","alternativeSequences":["C"]}}],"keywords":[{"id":"KW-1267","category":"Technical term","name":"Proteomics identification"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"15815621","citationType":"journal article","authors":["Hillier L.W.","Graves T.A.","Fulton R.S.","Fulton L.A.","Pepin K.H.","Minx P.","Wagner-McPherson C.","Layman D.","Wylie K.","Sekhon M.","Becker M.C.","Fewell G.A.","Delehaunty K.D.","Miner T.L.","Nash W.E.","Kremitzki C.","Oddy L.","Du H.","Sun H.","Bradshaw-Cordum H.","Ali J.","Carter J.","Cordes M.","Harris A.","Isak A.","van Brunt A.","Nguyen C.","Du F.","Courtney L.","Kalicki J.","Ozersky P.","Abbott S.","Armstrong J.","Belter E.A.","Caruso L.","Cedroni M.","Cotton M.","Davidson T.","Desai A.","Elliott G.","Erb T.","Fronick C.","Gaige T.","Haakenson W.","Haglund K.","Holmes A.","Harkins R.","Kim K.","Kruchowski S.S.","Strong C.M.","Grewal N.","Goyea E.","Hou S.","Levy A.","Martinka S.","Mead K.","McLellan M.D.","Meyer R.","Randall-Maher J.","Tomlinson C.","Dauphin-Kohlberg S.","Kozlowicz-Reilly A.","Shah N.","Swearengen-Shahid S.","Snider J.","Strong J.T.","Thompson J.","Yoakum M.","Leonard S.","Pearman C.","Trani L.","Radionenko M.","Waligorski J.E.","Wang C.","Rock S.M.","Tin-Wollam A.-M.","Maupin R.","Latreille P.","Wendl M.C.","Yang S.-P.","Pohl C.","Wallis J.W.","Spieth J.","Bieri T.A.","Berkowicz N.","Nelson J.O.","Osborne J.","Ding L.","Meyer R.","Sabo A.","Shotland Y.","Sinha P.","Wohldmann P.E.","Cook L.L.","Hickenbotham M.T.","Eldred J.","Williams D.","Jones T.A.","She X.","Ciccarelli F.D.","Izaurralde E.","Taylor J.","Schmutz J.","Myers R.M.","Cox D.R.","Huang X.","McPherson J.D.","Mardis E.R.","Clifton S.W.","Warren W.C.","Chinwalla A.T.","Eddy S.R.","Marra M.A.","Ovcharenko I.","Furey T.S.","Miller W.","Eichler E.E.","Bork P.","Suyama M.","Torrents D.","Waterston R.H.","Wilson R.K."],"citationCrossReferences":[{"database":"PubMed","id":"15815621"},{"database":"DOI","id":"10.1038/nature03466"}],"title":"Generation and annotation of the DNA sequences of human chromosomes 2 and 4.","publicationDate":"2005","journal":"Nature","firstPage":"724","lastPage":"731","volume":"434"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"]},{"referenceNumber":2,"citation":{"id":"14702039","citationType":"journal article","authors":["Ota T.","Suzuki Y.","Nishikawa T.","Otsuki T.","Sugiyama T.","Irie R.","Wakamatsu A.","Hayashi K.","Sato H.","Nagai K.","Kimura K.","Makita H.","Sekine M.","Obayashi M.","Nishi T.","Shibahara T.","Tanaka T.","Ishii S.","Yamamoto J.","Saito K.","Kawai Y.","Isono Y.","Nakamura Y.","Nagahari K.","Murakami K.","Yasuda T.","Iwayanagi T.","Wagatsuma M.","Shiratori A.","Sudo H.","Hosoiri T.","Kaku Y.","Kodaira H.","Kondo H.","Sugawara M.","Takahashi M.","Kanda K.","Yokoi T.","Furuya T.","Kikkawa E.","Omura Y.","Abe K.","Kamihara K.","Katsuta N.","Sato K.","Tanikawa M.","Yamazaki M.","Ninomiya K.","Ishibashi T.","Yamashita H.","Murakawa K.","Fujimori K.","Tanai H.","Kimata M.","Watanabe M.","Hiraoka S.","Chiba Y.","Ishida S.","Ono Y.","Takiguchi S.","Watanabe S.","Yosida M.","Hotuta T.","Kusano J.","Kanehori K.","Takahashi-Fujii A.","Hara H.","Tanase T.-O.","Nomura Y.","Togiya S.","Komai F.","Hara R.","Takeuchi K.","Arita M.","Imose N.","Musashino K.","Yuuki H.","Oshima A.","Sasaki N.","Aotsuka S.","Yoshikawa Y.","Matsunawa H.","Ichihara T.","Shiohata N.","Sano S.","Moriya S.","Momiyama H.","Satoh N.","Takami S.","Terashima Y.","Suzuki O.","Nakagawa S.","Senoh A.","Mizoguchi H.","Goto Y.","Shimizu F.","Wakebe H.","Hishigaki H.","Watanabe T.","Sugiyama A.","Takemoto M.","Kawakami B.","Yamazaki M.","Watanabe K.","Kumagai A.","Itakura S.","Fukuzumi Y.","Fujimori Y.","Komiyama M.","Tashiro H.","Tanigami A.","Fujiwara T.","Ono T.","Yamada K.","Fujii Y.","Ozaki K.","Hirao M.","Ohmori Y.","Kawabata A.","Hikiji T.","Kobatake N.","Inagaki H.","Ikema Y.","Okamoto S.","Okitani R.","Kawakami T.","Noguchi S.","Itoh T.","Shigeta K.","Senba T.","Matsumura K.","Nakajima Y.","Mizuno T.","Morinaga M.","Sasaki M.","Togashi T.","Oyama M.","Hata H.","Watanabe M.","Komatsu T.","Mizushima-Sugano J.","Satoh T.","Shirai Y.","Takahashi Y.","Nakagawa K.","Okumura K.","Nagase T.","Nomura N.","Kikuchi H.","Masuho Y.","Yamashita R.","Nakai K.","Yada T.","Nakamura Y.","Ohara O.","Isogai T.","Sugano S."],"citationCrossReferences":[{"database":"PubMed","id":"14702039"},{"database":"DOI","id":"10.1038/ng1285"}],"title":"Complete sequencing and characterization of 21,243 full-length human cDNAs.","publicationDate":"2004","journal":"Nat. Genet.","firstPage":"40","lastPage":"45","volume":"36"},"referencePositions":["PARTIAL NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Tongue","type":"TISSUE"}]},{"referenceNumber":3,"citation":{"id":"15489334","citationType":"journal article","authoringGroup":["The MGC Project Team"],"citationCrossReferences":[{"database":"PubMed","id":"15489334"},{"database":"DOI","id":"10.1101/gr.2596504"}],"title":"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).","publicationDate":"2004","journal":"Genome Res.","firstPage":"2121","lastPage":"2127","volume":"14"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-794"],"referenceComments":[{"value":"Skin","type":"TISSUE"}]},{"referenceNumber":4,"citation":{"id":"32073997","citationType":"journal article","authors":["Mattera R.","Williamson C.D.","Ren X.","Bonifacino J.S."],"citationCrossReferences":[{"database":"PubMed","id":"32073997"},{"database":"DOI","id":"10.1091/mbc.e19-11-0658"}],"title":"The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A.","publicationDate":"2020","journal":"Mol. Biol. Cell","firstPage":"963","lastPage":"979","volume":"31"},"referencePositions":["FUNCTION","INTERACTION WITH AKTIP"]},{"referenceNumber":5,"citation":{"id":"30420729","citationType":"journal article","authors":["Chan J.Y.","Ng A.Y.J.","Cheng C.L.","Nairismaegi M.L.","Venkatesh B.","Cheah D.M.Z.","Li S.T.","Chan S.H.","Ngeow J.","Laurensia Y.","Lim J.Q.","Pang J.W.L.","Nagarajan S.","Song T.","Chia B.","Tan J.","Huang D.","Goh Y.T.","Poon E.","Somasundaram N.","Tao M.","Quek R.H.H.","Farid M.","Khor C.C.","Bei J.X.","Tan S.Y.","Lim S.T.","Ong C.K.","Tang T."],"citationCrossReferences":[{"database":"PubMed","id":"30420729"},{"database":"DOI","id":"10.1038/s41408-018-0149-5"}],"title":"Whole exome sequencing identifies recessive germline mutations in FAM160A1 in familial NK/T cell lymphoma.","publicationDate":"2018","journal":"Blood Cancer J.","firstPage":"111","lastPage":"111","volume":"8"},"referencePositions":["VARIANT CYS-943"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AC092611","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AC097455","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AK125363","properties":[{"key":"ProteinId","value":"BAC86147.1"},{"key":"Status","value":"ALT_SEQ"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"BC014937","properties":[{"key":"ProteinId","value":"AAH14937.1"},{"key":"Status","value":"ALT_SEQ"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"CCDS","id":"CCDS47146.1","properties":[{"key":"Description","value":"-"}]},{"database":"RefSeq","id":"NP_001103447.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001109977.3"}]},{"database":"RefSeq","id":"NP_001335623.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001348694.2"}]},{"database":"RefSeq","id":"XP_005263256.1","properties":[{"key":"NucleotideSequenceId","value":"XM_005263199.2"}]},{"database":"RefSeq","id":"XP_011530522.1","properties":[{"key":"NucleotideSequenceId","value":"XM_011532220.3"}]},{"database":"RefSeq","id":"XP_011530523.1","properties":[{"key":"NucleotideSequenceId","value":"XM_011532221.3"}]},{"database":"RefSeq","id":"XP_011530525.1","properties":[{"key":"NucleotideSequenceId","value":"XM_011532223.3"}]},{"database":"RefSeq","id":"XP_011530526.1","properties":[{"key":"NucleotideSequenceId","value":"XM_011532224.3"}]},{"database":"RefSeq","id":"XP_024309969.1","properties":[{"key":"NucleotideSequenceId","value":"XM_024454201.2"}]},{"database":"RefSeq","id":"XP_047272083.1","properties":[{"key":"NucleotideSequenceId","value":"XM_047416127.1"}]},{"database":"RefSeq","id":"XP_054206755.1","properties":[{"key":"NucleotideSequenceId","value":"XM_054350780.1"}]},{"database":"RefSeq","id":"XP_054206756.1","properties":[{"key":"NucleotideSequenceId","value":"XM_054350781.1"}]},{"database":"RefSeq","id":"XP_054206757.1","properties":[{"key":"NucleotideSequenceId","value":"XM_054350782.1"}]},{"database":"RefSeq","id":"XP_054206758.1","properties":[{"key":"NucleotideSequenceId","value":"XM_054350783.1"}]},{"database":"RefSeq","id":"XP_054206759.1","properties":[{"key":"NucleotideSequenceId","value":"XM_054350784.1"}]},{"database":"RefSeq","id":"XP_054206760.1","properties":[{"key":"NucleotideSequenceId","value":"XM_054350785.1"}]},{"database":"RefSeq","id":"XP_054206761.1","properties":[{"key":"NucleotideSequenceId","value":"XM_054350786.1"}]},{"database":"AlphaFoldDB","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"610225","properties":[{"key":"Interactions","value":"33"}]},{"database":"ComplexPortal","id":"CPX-2353","properties":[{"key":"EntryName","value":"FTS-Hook-FHIP cargo adaptor complex, FHIP1A-HOOK1/3 variant"}]},{"database":"FunCoup","id":"Q05DH4","properties":[{"key":"Number of interactors","value":"586"}]},{"database":"IntAct","id":"Q05DH4","properties":[{"key":"Interactions","value":"135"}]},{"database":"NDEx","id":"MUSIC2-C5180-FHIP1A","properties":[{"key":"Evidences","value":"Osteosarcoma (U2OS) cell map - C5180 (62 proteins)"}]},{"database":"STRING","id":"9606.ENSP00000413196","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"PhosphoSitePlus","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"BioMuta","id":"FAM160A1","properties":[{"key":"Description","value":"-"}]},{"database":"DMDM","id":"189042274","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"MassIVE","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"9606-ENSP00000413196","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"ProteomicsDB","id":"58407","properties":[{"key":"Description","value":"-"}]},{"database":"Pumba","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"Antibodypedia","id":"48311","properties":[{"key":"antibodies","value":"8 antibodies from 7 providers"}]},{"database":"DNASU","id":"729830","properties":[{"key":"Description","value":"-"}]},{"database":"Ensembl","id":"ENST00000435205.6","properties":[{"key":"ProteinId","value":"ENSP00000413196.1"},{"key":"GeneId","value":"ENSG00000164142.17"}]},{"database":"Ensembl","id":"ENST00000505231.1","properties":[{"key":"ProteinId","value":"ENSP00000421580.1"},{"key":"GeneId","value":"ENSG00000164142.17"}]},{"database":"Ensembl","id":"ENST00000883036.1","properties":[{"key":"ProteinId","value":"ENSP00000553095.1"},{"key":"GeneId","value":"ENSG00000164142.17"}]},{"database":"Ensembl","id":"ENST00000883037.1","properties":[{"key":"ProteinId","value":"ENSP00000553096.1"},{"key":"GeneId","value":"ENSG00000164142.17"}]},{"database":"Ensembl","id":"ENST00000883038.1","properties":[{"key":"ProteinId","value":"ENSP00000553097.1"},{"key":"GeneId","value":"ENSG00000164142.17"}]},{"database":"Ensembl","id":"ENST00000883040.1","properties":[{"key":"ProteinId","value":"ENSP00000553099.1"},{"key":"GeneId","value":"ENSG00000164142.17"}]},{"database":"Ensembl","id":"ENST00000923453.1","properties":[{"key":"ProteinId","value":"ENSP00000593512.1"},{"key":"GeneId","value":"ENSG00000164142.17"}]},{"database":"Ensembl","id":"ENST00000923454.1","properties":[{"key":"ProteinId","value":"ENSP00000593513.1"},{"key":"GeneId","value":"ENSG00000164142.17"}]},{"database":"GeneID","id":"729830","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"hsa:729830","properties":[{"key":"Description","value":"-"}]},{"database":"MANE-Select","id":"ENST00000435205.6","properties":[{"key":"ProteinId","value":"ENSP00000413196.1"},{"key":"RefSeqNucleotideId","value":"NM_001109977.3"},{"key":"RefSeqProteinId","value":"NP_001103447.1"}]},{"database":"UCSC","id":"uc003imj.2","properties":[{"key":"OrganismName","value":"human"}]},{"database":"AGR","id":"HGNC:34237","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"729830","properties":[{"key":"Description","value":"-"}]},{"database":"DisGeNET","id":"729830","properties":[{"key":"Description","value":"-"}]},{"database":"GeneCards","id":"FHIP1A","properties":[{"key":"Description","value":"-"}]},{"database":"HGNC","id":"HGNC:34237","properties":[{"key":"GeneName","value":"FHIP1A"}]},{"database":"HPA","id":"ENSG00000164142","properties":[{"key":"ExpressionPatterns","value":"Tissue enhanced (skeletal)"}]},{"database":"OpenTargets","id":"ENSG00000164142","properties":[{"key":"Description","value":"-"}]},{"database":"VEuPathDB","id":"HostDB:ENSG00000164142","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG3695","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"GeneTree","id":"ENSGT00950000182936","properties":[{"key":"Description","value":"-"}]},{"database":"HOGENOM","id":"CLU_007807_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"RMPSLVQ","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"9181at9604","properties":[{"key":"Description","value":"-"}]},{"database":"PAN-GO","id":"Q05DH4","properties":[{"key":"Number of GO annotations","value":"0 GO annotations based on evolutionary models"}]},{"database":"PhylomeDB","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"PathwayCommons","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"SignaLink","id":"Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"Agora","id":"ENSG00000164142","properties":[{"key":"NominatedTarget","value":"-"}]},{"database":"BioGRID-ORCS","id":"729830","properties":[{"key":"hits","value":"11 hits in 1143 CRISPR screens"}]},{"database":"ChiTaRS","id":"FAM160A1","properties":[{"key":"OrganismName","value":"human"}]},{"database":"GenomeRNAi","id":"729830","properties":[{"key":"Description","value":"-"}]},{"database":"Pharos","id":"Q05DH4","properties":[{"key":"DevelopmentLevel","value":"Tdark"}]},{"database":"PRO","id":"PR:Q05DH4","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000005640","properties":[{"key":"Component","value":"Chromosome 4"}]},{"database":"RNAct","id":"Q05DH4","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"Bgee","id":"ENSG00000164142","properties":[{"key":"ExpressionPatterns","value":"Expressed in buccal mucosa cell and 162 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"Q05DH4","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0070695","properties":[{"key":"GoTerm","value":"C:FHF complex"},{"key":"GoEvidenceType","value":"NAS:ComplexPortal"}],"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"34882091"}]},{"database":"GO","id":"GO:1905719","properties":[{"key":"GoTerm","value":"P:protein localization to perinuclear region of cytoplasm"},{"key":"GoEvidenceType","value":"IMP:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"32073997"}]},{"database":"GO","id":"GO:0098840","properties":[{"key":"GoTerm","value":"P:protein transport along microtubule"},{"key":"GoEvidenceType","value":"NAS:ComplexPortal"}],"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"34882091"}]},{"database":"InterPro","id":"IPR019384","properties":[{"key":"EntryName","value":"FHIP"}]},{"database":"InterPro","id":"IPR045669","properties":[{"key":"EntryName","value":"FHIP_C"}]},{"database":"InterPro","id":"IPR045668","properties":[{"key":"EntryName","value":"FHIP_KELAA_motif"}]},{"database":"PANTHER","id":"PTHR21705:SF6","properties":[{"key":"EntryName","value":"FHF COMPLEX SUBUNIT HOOK-INTERACTING PROTEIN 1A"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR21705","properties":[{"key":"EntryName","value":"RAI16 PROTEIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF19314","properties":[{"key":"EntryName","value":"DUF5917"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF19311","properties":[{"key":"EntryName","value":"KELAA"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF10257","properties":[{"key":"EntryName","value":"RAI16-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MMSSVSTESKLQQAVSLQGVDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDEASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVSENIMEKLFLWSLRREFTDETKIEQLKMYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEKLVVLLNQLCSILAKDPSILELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVIQVAHPLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCSSGITLTLGNQERDYILWSKCMHDTSGPVERPFPEAFSESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPDPEMFLQSLTEEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQTELEWDDSYDTGISSGADVGSPGPYDDLEVSGPPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQEASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC","length":1040,"molWeight":116621,"crc64":"1B7A936DB0CAAFBD","md5":"B07568794D011DA8B9EA7FD932C0CF93"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"INTERACTION":1,"SIMILARITY":1,"SEQUENCE CAUTION":4},"countByFeatureType":{"Chain":1,"Region":3,"Compositional bias":4,"Natural variant":1},"uniParcId":"UPI00015DE720"}}