{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P94476","secondaryAccessions":["Q797B6"],"uniProtkbId":"YEBA_BACSU","entryAudit":{"firstPublicDate":"2009-01-20","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2009-05-26","entryVersion":117,"sequenceVersion":2},"annotationScore":2.0,"organism":{"scientificName":"Bacillus subtilis (strain 168)","taxonId":224308,"lineage":["Bacteria","Bacillati","Bacillota","Bacilli","Caryophanales","Bacillaceae","Bacillus"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized protein YebA"}}},"genes":[{"geneName":{"value":"yebA"},"orderedLocusNames":[{"value":"BSU06350"}]}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Cell membrane","id":"SL-0039"},"topology":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Frameshift","sequence":"AAB62310.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":737,"modifier":"EXACT"}},"description":"Uncharacterized protein YebA","featureId":"PRO_0000360581"},{"type":"Transmembrane","location":{"start":{"value":11,"modifier":"EXACT"},"end":{"value":31,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":36,"modifier":"EXACT"},"end":{"value":56,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":60,"modifier":"EXACT"},"end":{"value":80,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":118,"modifier":"EXACT"},"end":{"value":138,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":142,"modifier":"EXACT"},"end":{"value":162,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":164,"modifier":"EXACT"},"end":{"value":184,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":200,"modifier":"EXACT"},"end":{"value":220,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":618,"modifier":"EXACT"},"end":{"value":638,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Region","location":{"start":{"value":556,"modifier":"EXACT"},"end":{"value":611,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":581,"modifier":"EXACT"},"end":{"value":603,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Sequence conflict","location":{"start":{"value":607,"modifier":"EXACT"},"end":{"value":609,"modifier":"EXACT"}},"description":"in Ref. 1; AAB62310","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"PSA","alternativeSequences":["AVP"]}},{"type":"Sequence conflict","location":{"start":{"value":675,"modifier":"EXACT"},"end":{"value":675,"modifier":"EXACT"}},"description":"in Ref. 1; AAB62310","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"G","alternativeSequences":["A"]}}],"keywords":[{"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"8969499","citationType":"journal article","authors":["Borriss R.","Porwollik S.","Schroeter R."],"citationCrossReferences":[{"database":"PubMed","id":"8969499"},{"database":"DOI","id":"10.1099/13500872-142-11-3027"}],"title":"The 52 degrees-55 degrees segment of the Bacillus subtilis chromosome: a region devoted to purine uptake and metabolism, and containing the genes cotA, gabP and guaA and the pur gene cluster within a 34960 bp nucleotide sequence.","publicationDate":"1996","journal":"Microbiology","firstPage":"3027","lastPage":"3031","volume":"142"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"168","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9384377","citationType":"journal article","authors":["Kunst F.","Ogasawara N.","Moszer I.","Albertini A.M.","Alloni G.","Azevedo V.","Bertero M.G.","Bessieres P.","Bolotin A.","Borchert S.","Borriss R.","Boursier L.","Brans A.","Braun M.","Brignell S.C.","Bron S.","Brouillet S.","Bruschi C.V.","Caldwell B.","Capuano V.","Carter N.M.","Choi S.-K.","Codani J.-J.","Connerton I.F.","Cummings N.J.","Daniel R.A.","Denizot F.","Devine K.M.","Duesterhoeft A.","Ehrlich S.D.","Emmerson P.T.","Entian K.-D.","Errington J.","Fabret C.","Ferrari E.","Foulger D.","Fritz C.","Fujita M.","Fujita Y.","Fuma S.","Galizzi A.","Galleron N.","Ghim S.-Y.","Glaser P.","Goffeau A.","Golightly E.J.","Grandi G.","Guiseppi G.","Guy B.J.","Haga K.","Haiech J.","Harwood C.R.","Henaut A.","Hilbert H.","Holsappel S.","Hosono S.","Hullo M.-F.","Itaya M.","Jones L.-M.","Joris B.","Karamata D.","Kasahara Y.","Klaerr-Blanchard M.","Klein C.","Kobayashi Y.","Koetter P.","Koningstein G.","Krogh S.","Kumano M.","Kurita K.","Lapidus A.","Lardinois S.","Lauber J.","Lazarevic V.","Lee S.-M.","Levine A.","Liu H.","Masuda S.","Mauel C.","Medigue C.","Medina N.","Mellado R.P.","Mizuno M.","Moestl D.","Nakai S.","Noback M.","Noone D.","O'Reilly M.","Ogawa K.","Ogiwara A.","Oudega B.","Park S.-H.","Parro V.","Pohl T.M.","Portetelle D.","Porwollik S.","Prescott A.M.","Presecan E.","Pujic P.","Purnelle B.","Rapoport G.","Rey M.","Reynolds S.","Rieger M.","Rivolta C.","Rocha E.","Roche B.","Rose M.","Sadaie Y.","Sato T.","Scanlan E.","Schleich S.","Schroeter R.","Scoffone F.","Sekiguchi J.","Sekowska A.","Seror S.J.","Serror P.","Shin B.-S.","Soldo B.","Sorokin A.","Tacconi E.","Takagi T.","Takahashi H.","Takemaru K.","Takeuchi M.","Tamakoshi A.","Tanaka T.","Terpstra P.","Tognoni A.","Tosato V.","Uchiyama S.","Vandenbol M.","Vannier F.","Vassarotti A.","Viari A.","Wambutt R.","Wedler E.","Wedler H.","Weitzenegger T.","Winters P.","Wipat A.","Yamamoto H.","Yamane K.","Yasumoto K.","Yata K.","Yoshida K.","Yoshikawa H.-F.","Zumstein E.","Yoshikawa H.","Danchin A."],"citationCrossReferences":[{"database":"PubMed","id":"9384377"},{"database":"DOI","id":"10.1038/36786"}],"title":"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.","publicationDate":"1997","journal":"Nature","firstPage":"249","lastPage":"256","volume":"390"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"168","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"19383706","citationType":"journal article","authors":["Barbe V.","Cruveiller S.","Kunst F.","Lenoble P.","Meurice G.","Sekowska A.","Vallenet D.","Wang T.","Moszer I.","Medigue C.","Danchin A."],"citationCrossReferences":[{"database":"PubMed","id":"19383706"},{"database":"DOI","id":"10.1099/mic.0.027839-0"}],"title":"From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later.","publicationDate":"2009","journal":"Microbiology","firstPage":"1758","lastPage":"1775","volume":"155"},"referencePositions":["SEQUENCE REVISION"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"U51115","properties":[{"key":"ProteinId","value":"AAB62310.1"},{"key":"Status","value":"ALT_FRAME"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AL009126","properties":[{"key":"ProteinId","value":"CAB12454.2"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"E69791","properties":[{"key":"EntryName","value":"E69791"}]},{"database":"RefSeq","id":"NP_388516.2","properties":[{"key":"NucleotideSequenceId","value":"NC_000964.3"}]},{"database":"RefSeq","id":"WP_003242683.1","properties":[{"key":"NucleotideSequenceId","value":"NC_000964.3"}]},{"database":"AlphaFoldDB","id":"P94476","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P94476","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P94476","properties":[{"key":"Number of interactors","value":"203"}]},{"database":"STRING","id":"224308.BSU06350","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"224308-BSU06350","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"CAB12454","properties":[{"key":"ProteinId","value":"CAB12454"},{"key":"GeneId","value":"BSU_06350"}]},{"database":"GeneID","id":"936029","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"bsu:BSU06350","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|224308.179.peg.689","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"eggNOG","id":"COG1305","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"InParanoid","id":"P94476","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"9804872at2","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P94476","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"BSUB:BSU06350-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001570","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0003810","properties":[{"key":"GoTerm","value":"F:protein-glutamine gamma-glutamyltransferase activity"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"Gene3D","id":"3.10.620.30","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR052901","properties":[{"key":"EntryName","value":"Bact_TGase-like"}]},{"database":"InterPro","id":"IPR038765","properties":[{"key":"EntryName","value":"Papain-like_cys_pep_sf"}]},{"database":"InterPro","id":"IPR025403","properties":[{"key":"EntryName","value":"TgpA-like_C"}]},{"database":"InterPro","id":"IPR021878","properties":[{"key":"EntryName","value":"TgpA_N"}]},{"database":"InterPro","id":"IPR002931","properties":[{"key":"EntryName","value":"Transglutaminase-like"}]},{"database":"PANTHER","id":"PTHR42736","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR42736:SF1","properties":[{"key":"EntryName","value":"PROTEIN-GLUTAMINE GAMMA-GLUTAMYLTRANSFERASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF13559","properties":[{"key":"EntryName","value":"DUF4129"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF11992","properties":[{"key":"EntryName","value":"TgpA_N"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01841","properties":[{"key":"EntryName","value":"Transglut_core"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00460","properties":[{"key":"EntryName","value":"TGc"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF54001","properties":[{"key":"EntryName","value":"Cysteine proteinases"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MPHDDHKGSRLSLLLFYFLAFLLLWEWLRPLDSFTETKHTGFFSVFIGLTFLLTFFRMRWFVTVPFCVIFTLISIHILFYQGSIFDLSWVSSFLQDVYLNITLIQSGQWNDMIPSFRTLLFFVLLWLLVYLLHYWVIYQRRILFFFLMTVAYITILDTFTPYDATFAVIRIVLIGFFMLGLLYLERIKLMERITLPKTSVLKWFLPLSVLVLAATGFGLAAPKSEPAWPDPVPFLKKITHQDRVSAGESKIGYGNHDESLGGPFQQDATPVFTWQGKERTYFRVETKDTYTGKGWIETDTGMSYQLSNGKVENLWFDHKVATERRTVRVKVDKHYGYNHLMYPIGAETIQPKQAVSLEMNGNTEQISPISEQAGEIRNMGNYTVTYNSPVYKLDELRKVKVRKNSEEYTFSDRYMQLPDSLPERVRTLAIKLTQDHDNMFDKVKAVEDYLGSNAFTYETENVTIPKNDEDYVDQFLFETKMGYCDNFSSAMVVLLRSAGIPARWVKGYTSGEYKEAGNKNGSIYEVTNNNAHSWVEVYFPEQGWVTFEPTKGFTNPAQFTSSDTKDSGSDSSSSPKKAKEKQKEEKKQPQKEEKQKEKREPAVSKKPSASHTNAGAGLYAALAVLAVLLVAAVLLYVFRSLWIPVFAVRKLKRRSDQHAFFEAYGALLKQLKRKGLPKRDSETLRDYAKRIDEKYDIEDMSKLTLSYERALYRNEDSSALWNDSRELWENLIKRRWS","length":737,"molWeight":85402,"crc64":"B185F97EC663DD12","md5":"6A59572FA06B6D130F8F0E2D52249267"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1,"Transmembrane":8,"Region":1,"Compositional bias":1,"Sequence conflict":2},"uniParcId":"UPI000195C4C5"}}