{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P77699","secondaryAccessions":["A0A385XJC6"],"uniProtkbId":"TFAD_ECOLI","entryAudit":{"firstPublicDate":"1997-11-01","lastAnnotationUpdateDate":"2025-06-18","lastSequenceUpdateDate":"2016-11-02","entryVersion":108,"sequenceVersion":2},"annotationScore":2.0,"organism":{"scientificName":"Escherichia coli (strain K12)","taxonId":83333,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Protein TfaD"}},"alternativeNames":[{"fullName":{"value":"Tail fiber assembly protein homolog from lambdoid prophage DLP12"}}]},"genes":[{"geneName":{"value":"tfaD"},"synonyms":[{"value":"ybcX"}],"orderedLocusNames":[{"value":"b0561"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Encoded by the cryptic lambdoid prophage DLP12"}],"commentType":"MISCELLANEOUS"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"In the C-terminal section; belongs to the tfa family"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"AAB40757.1","note":"Extended N-terminus.","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":187,"modifier":"EXACT"}},"description":"Protein TfaD","featureId":"PRO_0000070304"}],"keywords":[{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-B1UJ6TNQ0SAS1","citationType":"submission","authors":["Chung E.","Allen E.","Araujo R.","Aparicio A.M.","Davis K.","Duncan M.","Federspiel N.","Hyman R.","Kalman S.","Komp C.","Kurdi O.","Lew H.","Lin D.","Namath A.","Oefner P.","Roberts D.","Schramm S.","Davis R.W."],"title":"Sequence of minutes 4-25 of Escherichia coli.","publicationDate":"JAN-1997","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / MG1655 / ATCC 47076","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9278503","citationType":"journal article","authors":["Blattner F.R.","Plunkett G. III","Bloch C.A.","Perna N.T.","Burland V.","Riley M.","Collado-Vides J.","Glasner J.D.","Rode C.K.","Mayhew G.F.","Gregor J.","Davis N.W.","Kirkpatrick H.A.","Goeden M.A.","Rose D.J.","Mau B.","Shao Y."],"citationCrossReferences":[{"database":"PubMed","id":"9278503"},{"database":"DOI","id":"10.1126/science.277.5331.1453"}],"title":"The complete genome sequence of Escherichia coli K-12.","publicationDate":"1997","journal":"Science","firstPage":"1453","lastPage":"1462","volume":"277"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / MG1655 / ATCC 47076","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"U82598","properties":[{"key":"ProteinId","value":"AAB40757.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"U00096","properties":[{"key":"ProteinId","value":"AYC08183.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"G64788","properties":[{"key":"EntryName","value":"G64788"}]},{"database":"AlphaFoldDB","id":"P77699","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P77699","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P77699","properties":[{"key":"Number of interactors","value":"20"}]},{"database":"EnsemblBacteria","id":"AYC08183","properties":[{"key":"ProteinId","value":"AYC08183"},{"key":"GeneId","value":"b0561"}]},{"database":"EchoBASE","id":"EB3404","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P77699","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"EcoCyc:G6315-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:P77699","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000625","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"InterPro","id":"IPR003458","properties":[{"key":"EntryName","value":"Phage_T4_Gp38_tail_assem"}]},{"database":"InterPro","id":"IPR051220","properties":[{"key":"EntryName","value":"TFA_Chaperone"}]},{"database":"PANTHER","id":"PTHR34413:SF2","properties":[{"key":"EntryName","value":"PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR34413","properties":[{"key":"EntryName","value":"PROPHAGE TAIL FIBER ASSEMBLY PROTEIN HOMOLOG TFAE-RELATED-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02413","properties":[{"key":"EntryName","value":"Caudo_TAP"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTLIPAGFVAVFNSDESSWHLVEDHRGKTVYDVASGDALFISELGPLPENVTWLSPEGEFQKWNGTAWVKDAEAEKLFRIREAEETKNSLMQVASEHIAPLQDAVDLEIATEEETSLLEAWKKYRVLLNRVDTSTAPDIEWPTNPVRE","length":187,"molWeight":21203,"crc64":"630CF347AFF76284","md5":"8B344070A7E3A9D5408CA774107A5D95"},"extraAttributes":{"countByCommentType":{"MISCELLANEOUS":1,"SIMILARITY":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI0000697585"}}