{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P76170","secondaryAccessions":["Q2MB79"],"uniProtkbId":"YNFB_ECOLI","entryAudit":{"firstPublicDate":"1998-07-15","lastAnnotationUpdateDate":"2026-06-10","lastSequenceUpdateDate":"1997-02-01","entryVersion":135,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Escherichia coli (strain K12)","taxonId":83333,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01581"}],"value":"UPF0482 protein YnfB"}},"flag":"Precursor"},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01581"}],"value":"ynfB"},"orderedLocusNames":[{"value":"b1583"},{"value":"JW1575"}]}],"comments":[{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"P76170","intActId":"EBI-544774"},"interactantTwo":{"uniProtKBAccession":"P0AFG8","geneName":"aceE","intActId":"EBI-542683"},"numberOfExperiments":2,"organismDiffer":false}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01581"}],"value":"Belongs to the UPF0482 family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_01581"}]},{"type":"Chain","location":{"start":{"value":29,"modifier":"EXACT"},"end":{"value":113,"modifier":"EXACT"}},"description":"UPF0482 protein YnfB","featureId":"PRO_0000013848"}],"keywords":[{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0732","category":"Domain","name":"Signal"}],"references":[{"referenceNumber":1,"citation":{"id":"9278503","citationType":"journal article","authors":["Blattner F.R.","Plunkett G. III","Bloch C.A.","Perna N.T.","Burland V.","Riley M.","Collado-Vides J.","Glasner J.D.","Rode C.K.","Mayhew G.F.","Gregor J.","Davis N.W.","Kirkpatrick H.A.","Goeden M.A.","Rose D.J.","Mau B.","Shao Y."],"citationCrossReferences":[{"database":"PubMed","id":"9278503"},{"database":"DOI","id":"10.1126/science.277.5331.1453"}],"title":"The complete genome sequence of Escherichia coli K-12.","publicationDate":"1997","journal":"Science","firstPage":"1453","lastPage":"1462","volume":"277"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / MG1655 / ATCC 47076","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"16738553","citationType":"journal article","authors":["Hayashi K.","Morooka N.","Yamamoto Y.","Fujita K.","Isono K.","Choi S.","Ohtsubo E.","Baba T.","Wanner B.L.","Mori H.","Horiuchi T."],"citationCrossReferences":[{"database":"PubMed","id":"16738553"},{"database":"DOI","id":"10.1038/msb4100049"}],"title":"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.","publicationDate":"2006","journal":"Mol. Syst. Biol.","firstPage":"E1","lastPage":"E5","volume":"2"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / W3110 / ATCC 27325 / DSM 5911","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"U00096","properties":[{"key":"ProteinId","value":"AAC74655.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AP009048","properties":[{"key":"ProteinId","value":"BAE76477.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"A64914","properties":[{"key":"EntryName","value":"A64914"}]},{"database":"RefSeq","id":"NP_416100.1","properties":[{"key":"NucleotideSequenceId","value":"NC_000913.3"}]},{"database":"RefSeq","id":"WP_000705211.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP009789.1"}]},{"database":"AlphaFoldDB","id":"P76170","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"4260818","properties":[{"key":"Interactions","value":"30"}]},{"database":"DIP","id":"DIP-12762N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P76170","properties":[{"key":"Number of interactors","value":"91"}]},{"database":"IntAct","id":"P76170","properties":[{"key":"Interactions","value":"3"}]},{"database":"STRING","id":"511145.b1583","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"P76170","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"511145-b1583","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"AAC74655","properties":[{"key":"ProteinId","value":"AAC74655"},{"key":"GeneId","value":"b1583"}]},{"database":"GeneID","id":"946119","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecj:JW1575","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"eco:b1583","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecoc:C3026_09125","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|511145.12.peg.1654","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"EchoBASE","id":"EB3601","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG5032SRB","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"HOGENOM","id":"CLU_167574_0_0_6","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P76170","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"EPNTERC","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"6455281at2","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P76170","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"EcoCyc:G6841-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:P76170","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000625","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"AbasyAtlas","id":"P76170","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0009279","properties":[{"key":"GoTerm","value":"C:cell outer membrane"},{"key":"GoEvidenceType","value":"IDA:EcoCyc"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"15911532"}]},{"database":"HAMAP","id":"MF_01581","properties":[{"key":"EntryName","value":"UPF0482"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR009700","properties":[{"key":"EntryName","value":"DUF1283"}]},{"database":"NCBIfam","id":"NF010180","properties":[{"key":"EntryName","value":"PRK13659.1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF06932","properties":[{"key":"EntryName","value":"DUF1283"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKITLSKRIGLLAILLPCALALSTTVHAETNKLVIESGDSAQSRQHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRCLDRRTGRVITP","length":113,"molWeight":12909,"crc64":"54CD449B384A7418","md5":"0CF2EA0C11BDCB07E43C5CE7EDEF3229"},"extraAttributes":{"countByCommentType":{"INTERACTION":1,"SIMILARITY":1},"countByFeatureType":{"Signal":1,"Chain":1},"uniParcId":"UPI000013BB29"}}