{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P75809","uniProtkbId":"YBJI_ECOLI","entryAudit":{"firstPublicDate":"2000-05-30","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"2000-05-30","entryVersion":163,"sequenceVersion":3},"annotationScore":5.0,"organism":{"scientificName":"Escherichia coli (strain K12)","taxonId":83333,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"24123841"}],"value":"5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YbjI"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"24123841"}],"value":"3.1.3.104"}]}},"genes":[{"geneName":{"value":"ybjI"},"orderedLocusNames":[{"value":"b0844"},{"value":"JW5113"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"15808744"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16990279"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"24123841"}],"value":"Catalyzes the dephosphorylation of 5-amino-6-(5-phospho-D-ribitylamino)uracil, and thus could be involved in the riboflavin biosynthesis pathway (PubMed:24123841). Is also able to dephosphorylate flavin mononucleotide (FMN), erythrose 4-phosphate and other phosphoric acid esters (PubMed:15808744, PubMed:16990279, PubMed:24123841)"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"5-amino-6-(5-phospho-D-ribitylamino)uracil + H2O = 5-amino-6-(D-ribitylamino)uracil + phosphate","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:25197"},{"database":"ChEBI","id":"CHEBI:15377"},{"database":"ChEBI","id":"CHEBI:15934"},{"database":"ChEBI","id":"CHEBI:43474"},{"database":"ChEBI","id":"CHEBI:58421"}],"ecNumber":"3.1.3.104","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"24123841"}]}},{"commentType":"COFACTOR","cofactors":[{"name":"Mg(2+)","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16990279"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:18420"}},{"name":"Mn(2+)","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16990279"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:29035"}},{"name":"Co(2+)","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16990279"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:48828"}},{"name":"Zn(2+)","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16990279"}],"cofactorCrossReference":{"database":"ChEBI","id":"CHEBI:29105"}}],"note":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16990279"}],"value":"Magnesium. Can also use other divalent metal cations as manganese, cobalt or zinc."}]}},{"commentType":"BIOPHYSICOCHEMICAL PROPERTIES","kineticParameters":{"maximumVelocities":[{"velocity":3.0,"unit":"umol/min/mg","enzyme":"enzyme with 5-amino-6-(5-phospho-D-ribitylamino)uracil as substrate","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"24123841"}]}],"michaelisConstants":[{"constant":70.0,"unit":"uM","substrate":"5-amino-6-(5-phospho-D-ribitylamino)uracil","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"24123841"}]},{"constant":2.3,"unit":"mM","substrate":"FMN (in the presence of magnesium ion as cofactor and at pH 9)","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16990279"}]},{"constant":2.6,"unit":"mM","substrate":"Ery4P (in the presence of magnesium ion as cofactor and at pH 9)","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16990279"}]}]},"phDependence":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"16990279"}],"value":"Optimum pH is 6-7.5."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"24123841"}],"value":"Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 4/4"}],"commentType":"PATHWAY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"24123841"}],"value":"Cells lacking this gene can grow in the absence of exogenous riboflavin; this may be due to the presence of the functionally redundant protein YigB"}],"commentType":"DISRUPTION PHENOTYPE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the HAD-like hydrolase superfamily. Cof family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":271,"modifier":"EXACT"}},"description":"5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YbjI","featureId":"PRO_0000054422"},{"type":"Active site","location":{"start":{"value":9,"modifier":"EXACT"},"end":{"value":9,"modifier":"EXACT"}},"description":"Nucleophile","evidences":[{"evidenceCode":"ECO:0000250"}]},{"type":"Binding site","location":{"start":{"value":9,"modifier":"EXACT"},"end":{"value":9,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:18420"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"Mg(2+)","id":"ChEBI:CHEBI:18420"}},{"type":"Binding site","location":{"start":{"value":10,"modifier":"EXACT"},"end":{"value":10,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:43474"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"phosphate","id":"ChEBI:CHEBI:43474"}},{"type":"Binding site","location":{"start":{"value":11,"modifier":"EXACT"},"end":{"value":11,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:18420"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"Mg(2+)","id":"ChEBI:CHEBI:18420"}},{"type":"Binding site","location":{"start":{"value":44,"modifier":"EXACT"},"end":{"value":45,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:43474"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"phosphate","id":"ChEBI:CHEBI:43474"}},{"type":"Binding site","location":{"start":{"value":192,"modifier":"EXACT"},"end":{"value":192,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:43474"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"phosphate","id":"ChEBI:CHEBI:43474"}},{"type":"Binding site","location":{"start":{"value":215,"modifier":"EXACT"},"end":{"value":215,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:18420"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"Mg(2+)","id":"ChEBI:CHEBI:18420"}},{"type":"Binding site","location":{"start":{"value":218,"modifier":"EXACT"},"end":{"value":218,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:43474"}],"evidences":[{"evidenceCode":"ECO:0000250"}],"ligand":{"name":"phosphate","id":"ChEBI:CHEBI:43474"}}],"keywords":[{"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"id":"KW-0460","category":"Ligand","name":"Magnesium"},{"id":"KW-0479","category":"Ligand","name":"Metal-binding"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"8905232","citationType":"journal article","authors":["Oshima T.","Aiba H.","Baba T.","Fujita K.","Hayashi K.","Honjo A.","Ikemoto K.","Inada T.","Itoh T.","Kajihara M.","Kanai K.","Kashimoto K.","Kimura S.","Kitagawa M.","Makino K.","Masuda S.","Miki T.","Mizobuchi K.","Mori H.","Motomura K.","Nakamura Y.","Nashimoto H.","Nishio Y.","Saito N.","Sampei G.","Seki Y.","Tagami H.","Takemoto K.","Wada C.","Yamamoto Y.","Yano M.","Horiuchi T."],"citationCrossReferences":[{"database":"PubMed","id":"8905232"},{"database":"DOI","id":"10.1093/dnares/3.3.137"}],"title":"A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 12.7-28.0 min region on the linkage map.","publicationDate":"1996","journal":"DNA Res.","firstPage":"137","lastPage":"155","volume":"3"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / W3110 / ATCC 27325 / DSM 5911","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9278503","citationType":"journal article","authors":["Blattner F.R.","Plunkett G. III","Bloch C.A.","Perna N.T.","Burland V.","Riley M.","Collado-Vides J.","Glasner J.D.","Rode C.K.","Mayhew G.F.","Gregor J.","Davis N.W.","Kirkpatrick H.A.","Goeden M.A.","Rose D.J.","Mau B.","Shao Y."],"citationCrossReferences":[{"database":"PubMed","id":"9278503"},{"database":"DOI","id":"10.1126/science.277.5331.1453"}],"title":"The complete genome sequence of Escherichia coli K-12.","publicationDate":"1997","journal":"Science","firstPage":"1453","lastPage":"1462","volume":"277"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / MG1655 / ATCC 47076","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"16738553","citationType":"journal article","authors":["Hayashi K.","Morooka N.","Yamamoto Y.","Fujita K.","Isono K.","Choi S.","Ohtsubo E.","Baba T.","Wanner B.L.","Mori H.","Horiuchi T."],"citationCrossReferences":[{"database":"PubMed","id":"16738553"},{"database":"DOI","id":"10.1038/msb4100049"}],"title":"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.","publicationDate":"2006","journal":"Mol. Syst. Biol.","firstPage":"E1","lastPage":"E5","volume":"2"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / W3110 / ATCC 27325 / DSM 5911","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"10493123","citationType":"journal article","authors":["Fountoulakis M.","Takacs M.-F.","Berndt P.","Langen H.","Takacs B."],"citationCrossReferences":[{"database":"PubMed","id":"10493123"},{"database":"DOI","id":"10.1002/(sici)1522-2683(19990801)20:11<2181::aid-elps2181>3.0.co;2-q"}],"title":"Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite chromatography.","publicationDate":"1999","journal":"Electrophoresis","firstPage":"2181","lastPage":"2195","volume":"20"},"referencePositions":["IDENTIFICATION BY MASS SPECTROMETRY"],"referenceComments":[{"value":"B / BL21","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"15808744","citationType":"journal article","authors":["Kuznetsova E.","Proudfoot M.","Sanders S.A.","Reinking J.","Savchenko A.","Arrowsmith C.H.","Edwards A.M.","Yakunin A.F."],"citationCrossReferences":[{"database":"PubMed","id":"15808744"},{"database":"DOI","id":"10.1016/j.femsre.2004.12.006"}],"title":"Enzyme genomics: application of general enzymatic screens to discover new enzymes.","publicationDate":"2005","journal":"FEMS Microbiol. Rev.","firstPage":"263","lastPage":"279","volume":"29"},"referencePositions":["FUNCTION AS A PHOSPHATASE"]},{"referenceNumber":6,"citation":{"id":"16990279","citationType":"journal article","authors":["Kuznetsova E.","Proudfoot M.","Gonzalez C.F.","Brown G.","Omelchenko M.V.","Borozan I.","Carmel L.","Wolf Y.I.","Mori H.","Savchenko A.V.","Arrowsmith C.H.","Koonin E.V.","Edwards A.M.","Yakunin A.F."],"citationCrossReferences":[{"database":"PubMed","id":"16990279"},{"database":"DOI","id":"10.1074/jbc.m605449200"}],"title":"Genome-wide analysis of substrate specificities of the Escherichia coli haloacid dehalogenase-like phosphatase family.","publicationDate":"2006","journal":"J. Biol. Chem.","firstPage":"36149","lastPage":"36161","volume":"281"},"referencePositions":["FUNCTION AS A PHOSPHATASE","BIOPHYSICOCHEMICAL PROPERTIES","SUBSTRATE SPECIFICITY","COFACTOR"]},{"referenceNumber":7,"citation":{"id":"24123841","citationType":"journal article","authors":["Haase I.","Sarge S.","Illarionov B.","Laudert D.","Hohmann H.P.","Bacher A.","Fischer M."],"citationCrossReferences":[{"database":"PubMed","id":"24123841"},{"database":"DOI","id":"10.1002/cbic.201300544"}],"title":"Enzymes from the haloacid dehalogenase (HAD) superfamily catalyse the elusive dephosphorylation step of riboflavin biosynthesis.","publicationDate":"2013","journal":"ChemBioChem","firstPage":"2272","lastPage":"2275","volume":"14"},"referencePositions":["FUNCTION","CATALYTIC ACTIVITY","BIOPHYSICOCHEMICAL PROPERTIES","SUBSTRATE SPECIFICITY","PATHWAY","DISRUPTION PHENOTYPE"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"U00096","properties":[{"key":"ProteinId","value":"AAC73931.2"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AP009048","properties":[{"key":"ProteinId","value":"BAA35548.2"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"D64822","properties":[{"key":"EntryName","value":"D64822"}]},{"database":"RefSeq","id":"NP_415365.4","properties":[{"key":"NucleotideSequenceId","value":"NC_000913.3"}]},{"database":"RefSeq","id":"WP_000023565.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP009789.1"}]},{"database":"AlphaFoldDB","id":"P75809","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P75809","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"4262830","properties":[{"key":"Interactions","value":"128"}]},{"database":"FunCoup","id":"P75809","properties":[{"key":"Number of interactors","value":"183"}]},{"database":"STRING","id":"511145.b0844","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"P75809","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"511145-b0844","properties":[{"key":"Description","value":"-"}]},{"database":"DNASU","id":"945470","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"AAC73931","properties":[{"key":"ProteinId","value":"AAC73931"},{"key":"GeneId","value":"b0844"}]},{"database":"GeneID","id":"945470","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecj:JW5113","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"eco:b0844","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecoc:C3026_05275","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|1411691.4.peg.1434","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"EchoBASE","id":"EB3442","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"COG0561","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"HOGENOM","id":"CLU_044146_5_0_6","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P75809","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"PHNNEEG","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"3180855at2","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P75809","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"EcoCyc:G6442-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"MetaCyc:G6442-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00275","properties":[{"key":"RectionId","value":"UER00403"}]},{"database":"PRO","id":"PR:P75809","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000625","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0043726","properties":[{"key":"GoTerm","value":"F:5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity"},{"key":"GoEvidenceType","value":"IDA:EcoCyc"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"24123841"}]},{"database":"GO","id":"GO:0000287","properties":[{"key":"GoTerm","value":"F:magnesium ion binding"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"16990279"}]},{"database":"GO","id":"GO:0016791","properties":[{"key":"GoTerm","value":"F:phosphatase activity"},{"key":"GoEvidenceType","value":"IDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"16990279"}]},{"database":"GO","id":"GO:0009231","properties":[{"key":"GoTerm","value":"P:riboflavin biosynthetic process"},{"key":"GoEvidenceType","value":"IDA:EcoCyc"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"24123841"}]},{"database":"CDD","id":"cd07518","properties":[{"key":"EntryName","value":"HAD_YbiV-Like"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.1240.10:FF:000010","properties":[{"key":"EntryName","value":"5-amino-6-(5-phospho-D-ribitylamino)uracil phosphatase YbjI"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.1240.10","properties":[{"key":"EntryName","value":"-"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.1000","properties":[{"key":"EntryName","value":"HAD superfamily/HAD-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000150","properties":[{"key":"EntryName","value":"Cof"}]},{"database":"InterPro","id":"IPR036412","properties":[{"key":"EntryName","value":"HAD-like_sf"}]},{"database":"InterPro","id":"IPR006379","properties":[{"key":"EntryName","value":"HAD-SF_hydro_IIB"}]},{"database":"InterPro","id":"IPR023214","properties":[{"key":"EntryName","value":"HAD_sf"}]},{"database":"NCBIfam","id":"TIGR00099","properties":[{"key":"EntryName","value":"Cof-subfamily"},{"key":"MatchStatus","value":"1"}]},{"database":"NCBIfam","id":"TIGR01484","properties":[{"key":"EntryName","value":"HAD-SF-IIB"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10000:SF53","properties":[{"key":"EntryName","value":"5-AMINO-6-(5-PHOSPHO-D-RIBITYLAMINO)URACIL PHOSPHATASE YBJI-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10000","properties":[{"key":"EntryName","value":"PHOSPHOSERINE PHOSPHATASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF08282","properties":[{"key":"EntryName","value":"Hydrolase_3"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDG01144","properties":[{"key":"EntryName","value":"C2.B.4:_PGP_Like"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDG01140","properties":[{"key":"EntryName","value":"C2.B:_Phosphomannomutase_and_P"},{"key":"MatchStatus","value":"1"}]},{"database":"SFLD","id":"SFLDS00003","properties":[{"key":"EntryName","value":"Haloacid_Dehalogenase"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56784","properties":[{"key":"EntryName","value":"HAD-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS01229","properties":[{"key":"EntryName","value":"COF_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVASGNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVFNGELSKDAFATVVEHLLTRPEVEIIACGKNSAYTLKKYDDAMKTVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQVQKALHEAIGDIMVSVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGNDIEMLRQAGFSFAMENAGSAVVAAAKYRAGSNNREGVLDVIDKVLKHEAPFDQ","length":271,"molWeight":30196,"crc64":"AF44E565BCB68BA9","md5":"76FD2BC51850AE4283C3CFA8D3828D41"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"COFACTOR":1,"BIOPHYSICOCHEMICAL PROPERTIES":1,"PATHWAY":1,"DISRUPTION PHENOTYPE":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Active site":1,"Binding site":7},"uniParcId":"UPI000013A38B"}}