{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P71311","secondaryAccessions":["P75699","Q2MC61"],"uniProtkbId":"YAIS_ECOLI","entryAudit":{"firstPublicDate":"1997-11-01","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"1997-02-01","entryVersion":138,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Escherichia coli (strain K12)","taxonId":83333,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized deacetylase YaiS"},"ecNumbers":[{"value":"3.-.-.-"}]}},"genes":[{"geneName":{"value":"yaiS"},"orderedLocusNames":[{"value":"b0364"},{"value":"JW0356"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the PIGL family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":185,"modifier":"EXACT"}},"description":"Uncharacterized deacetylase YaiS","featureId":"PRO_0000168595"}],"keywords":[{"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"8808933","citationType":"journal article","authors":["van der Ploeg J.R.","Weiss M.A.","Saller E.","Nashimoto H.","Saito N.","Kertesz M.A.","Leisinger T."],"citationCrossReferences":[{"database":"PubMed","id":"8808933"},{"database":"DOI","id":"10.1128/jb.178.18.5438-5446.1996"}],"title":"Identification of sulfate starvation-regulated genes in Escherichia coli: a gene cluster involved in the utilization of taurine as a sulfur source.","publicationDate":"1996","journal":"J. Bacteriol.","firstPage":"5438","lastPage":"5446","volume":"178"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"K12","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"CI-B1UJ6TNQ0SAS1","citationType":"submission","authors":["Chung E.","Allen E.","Araujo R.","Aparicio A.M.","Davis K.","Duncan M.","Federspiel N.","Hyman R.","Kalman S.","Komp C.","Kurdi O.","Lew H.","Lin D.","Namath A.","Oefner P.","Roberts D.","Schramm S.","Davis R.W."],"title":"Sequence of minutes 4-25 of Escherichia coli.","publicationDate":"JAN-1997","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / MG1655 / ATCC 47076","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"9278503","citationType":"journal article","authors":["Blattner F.R.","Plunkett G. III","Bloch C.A.","Perna N.T.","Burland V.","Riley M.","Collado-Vides J.","Glasner J.D.","Rode C.K.","Mayhew G.F.","Gregor J.","Davis N.W.","Kirkpatrick H.A.","Goeden M.A.","Rose D.J.","Mau B.","Shao Y."],"citationCrossReferences":[{"database":"PubMed","id":"9278503"},{"database":"DOI","id":"10.1126/science.277.5331.1453"}],"title":"The complete genome sequence of Escherichia coli K-12.","publicationDate":"1997","journal":"Science","firstPage":"1453","lastPage":"1462","volume":"277"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / MG1655 / ATCC 47076","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"16738553","citationType":"journal article","authors":["Hayashi K.","Morooka N.","Yamamoto Y.","Fujita K.","Isono K.","Choi S.","Ohtsubo E.","Baba T.","Wanner B.L.","Mori H.","Horiuchi T."],"citationCrossReferences":[{"database":"PubMed","id":"16738553"},{"database":"DOI","id":"10.1038/msb4100049"}],"title":"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.","publicationDate":"2006","journal":"Mol. Syst. Biol.","firstPage":"E1","lastPage":"E5","volume":"2"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / W3110 / ATCC 27325 / DSM 5911","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"D85613","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"U73857","properties":[{"key":"ProteinId","value":"AAB18087.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"U00096","properties":[{"key":"ProteinId","value":"AAC73467.2"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AP009048","properties":[{"key":"ProteinId","value":"BAE76145.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"D64764","properties":[{"key":"EntryName","value":"D64764"}]},{"database":"RefSeq","id":"NP_414898.4","properties":[{"key":"NucleotideSequenceId","value":"NC_000913.3"}]},{"database":"RefSeq","id":"WP_000362028.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP009789.1"}]},{"database":"AlphaFoldDB","id":"P71311","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P71311","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"4261089","properties":[{"key":"Interactions","value":"194"}]},{"database":"DIP","id":"DIP-11278N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P71311","properties":[{"key":"Number of interactors","value":"62"}]},{"database":"STRING","id":"511145.b0364","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"511145-b0364","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"AAC73467","properties":[{"key":"ProteinId","value":"AAC73467"},{"key":"GeneId","value":"b0364"}]},{"database":"GeneID","id":"946967","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecj:JW0356","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"eco:b0364","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|511145.12.peg.375","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"EchoBASE","id":"EB3087","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"COG2120","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"HOGENOM","id":"CLU_049311_5_2_6","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P71311","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"PDNRMDS","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"9790023at2","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P71311","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"EcoCyc:G6216-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:P71311","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000625","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"GO","id":"GO:0016811","properties":[{"key":"GoTerm","value":"F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"Gene3D","id":"3.40.50.10320","properties":[{"key":"EntryName","value":"LmbE-like"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR003737","properties":[{"key":"EntryName","value":"GlcNAc_PI_deacetylase-related"}]},{"database":"InterPro","id":"IPR024078","properties":[{"key":"EntryName","value":"LmbE-like_dom_sf"}]},{"database":"PANTHER","id":"PTHR12993:SF30","properties":[{"key":"EntryName","value":"N-ACETYL-ALPHA-D-GLUCOSAMINYL L-MALATE DEACETYLASE 1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR12993","properties":[{"key":"EntryName","value":"N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL DE-N-ACETYLASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02585","properties":[{"key":"EntryName","value":"PIG-L"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF102588","properties":[{"key":"EntryName","value":"LmbE-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDKVLDSALLSSANKRKGILAIGAHPDDIELGCGASLARLAQKGIYIAAVVMTTGNSGTDGIIDRHEESRNALKILGCHQTIHLNFADTRAHLQLNDMISALEDIIKNQIPSDVEIMRVYTMHDADRHQDHLAVYQASMVACRTIPQILGYETPSTWLSFMPQVFESVKEEYFTVKLAALKKHKS","length":185,"molWeight":20487,"crc64":"E1B257D4EB3CC6DA","md5":"1A6966FE480A96F12C4F1EE392DCE1F3"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI000013A0DB"}}