{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P71036","secondaryAccessions":["Q794Z7"],"uniProtkbId":"YWNA_BACSU","entryAudit":{"firstPublicDate":"2009-01-20","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1997-02-01","entryVersion":131,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Bacillus subtilis (strain 168)","taxonId":224308,"lineage":["Bacteria","Bacillati","Bacillota","Bacilli","Caryophanales","Bacillaceae","Bacillus"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Putative HTH-type transcriptional regulator YwnA"}}},"genes":[{"geneName":{"value":"ywnA"},"orderedLocusNames":[{"value":"BSU36630"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":133,"modifier":"EXACT"}},"description":"Putative HTH-type transcriptional regulator YwnA","featureId":"PRO_0000360420"},{"type":"Domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":130,"modifier":"EXACT"}},"description":"HTH rrf2-type","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00540"}]},{"type":"DNA binding","location":{"start":{"value":24,"modifier":"EXACT"},"end":{"value":47,"modifier":"EXACT"}},"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00540"}]},{"type":"Helix","location":{"start":{"value":5,"modifier":"EXACT"},"end":{"value":17,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]},{"type":"Helix","location":{"start":{"value":24,"modifier":"EXACT"},"end":{"value":31,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]},{"type":"Helix","location":{"start":{"value":35,"modifier":"EXACT"},"end":{"value":47,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]},{"type":"Beta strand","location":{"start":{"value":50,"modifier":"EXACT"},"end":{"value":52,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]},{"type":"Beta strand","location":{"start":{"value":55,"modifier":"EXACT"},"end":{"value":59,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]},{"type":"Beta strand","location":{"start":{"value":61,"modifier":"EXACT"},"end":{"value":64,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]},{"type":"Helix","location":{"start":{"value":66,"modifier":"EXACT"},"end":{"value":68,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]},{"type":"Helix","location":{"start":{"value":71,"modifier":"EXACT"},"end":{"value":78,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]},{"type":"Helix","location":{"start":{"value":96,"modifier":"EXACT"},"end":{"value":120,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]},{"type":"Helix","location":{"start":{"value":125,"modifier":"EXACT"},"end":{"value":128,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1XD7"}]}],"keywords":[{"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"9150240","citationType":"journal article","authors":["Cruz-Ramos H.","Glaser P.","Wray L.V. Jr.","Fisher S.H."],"citationCrossReferences":[{"database":"PubMed","id":"9150240"},{"database":"DOI","id":"10.1128/jb.179.10.3371-3373.1997"}],"title":"The Bacillus subtilis ureABC operon.","publicationDate":"1997","journal":"J. Bacteriol.","firstPage":"3371","lastPage":"3373","volume":"179"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"168","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9384377","citationType":"journal article","authors":["Kunst F.","Ogasawara N.","Moszer I.","Albertini A.M.","Alloni G.","Azevedo V.","Bertero M.G.","Bessieres P.","Bolotin A.","Borchert S.","Borriss R.","Boursier L.","Brans A.","Braun M.","Brignell S.C.","Bron S.","Brouillet S.","Bruschi C.V.","Caldwell B.","Capuano V.","Carter N.M.","Choi S.-K.","Codani J.-J.","Connerton I.F.","Cummings N.J.","Daniel R.A.","Denizot F.","Devine K.M.","Duesterhoeft A.","Ehrlich S.D.","Emmerson P.T.","Entian K.-D.","Errington J.","Fabret C.","Ferrari E.","Foulger D.","Fritz C.","Fujita M.","Fujita Y.","Fuma S.","Galizzi A.","Galleron N.","Ghim S.-Y.","Glaser P.","Goffeau A.","Golightly E.J.","Grandi G.","Guiseppi G.","Guy B.J.","Haga K.","Haiech J.","Harwood C.R.","Henaut A.","Hilbert H.","Holsappel S.","Hosono S.","Hullo M.-F.","Itaya M.","Jones L.-M.","Joris B.","Karamata D.","Kasahara Y.","Klaerr-Blanchard M.","Klein C.","Kobayashi Y.","Koetter P.","Koningstein G.","Krogh S.","Kumano M.","Kurita K.","Lapidus A.","Lardinois S.","Lauber J.","Lazarevic V.","Lee S.-M.","Levine A.","Liu H.","Masuda S.","Mauel C.","Medigue C.","Medina N.","Mellado R.P.","Mizuno M.","Moestl D.","Nakai S.","Noback M.","Noone D.","O'Reilly M.","Ogawa K.","Ogiwara A.","Oudega B.","Park S.-H.","Parro V.","Pohl T.M.","Portetelle D.","Porwollik S.","Prescott A.M.","Presecan E.","Pujic P.","Purnelle B.","Rapoport G.","Rey M.","Reynolds S.","Rieger M.","Rivolta C.","Rocha E.","Roche B.","Rose M.","Sadaie Y.","Sato T.","Scanlan E.","Schleich S.","Schroeter R.","Scoffone F.","Sekiguchi J.","Sekowska A.","Seror S.J.","Serror P.","Shin B.-S.","Soldo B.","Sorokin A.","Tacconi E.","Takagi T.","Takahashi H.","Takemaru K.","Takeuchi M.","Tamakoshi A.","Tanaka T.","Terpstra P.","Tognoni A.","Tosato V.","Uchiyama S.","Vandenbol M.","Vannier F.","Vassarotti A.","Viari A.","Wambutt R.","Wedler E.","Wedler H.","Weitzenegger T.","Winters P.","Wipat A.","Yamamoto H.","Yamane K.","Yasumoto K.","Yata K.","Yoshida K.","Yoshikawa H.-F.","Zumstein E.","Yoshikawa H.","Danchin A."],"citationCrossReferences":[{"database":"PubMed","id":"9384377"},{"database":"DOI","id":"10.1038/36786"}],"title":"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.","publicationDate":"1997","journal":"Nature","firstPage":"249","lastPage":"256","volume":"390"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"168","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"CI-3IADITJ0U30F3","citationType":"submission","authoringGroup":["New York structural genomix research consortium (NYSGXRC)"],"title":"Crystal structure of a putative DNA binding protein.","publicationDate":"JAN-2005","submissionDatabase":"PDB data bank"},"referencePositions":["X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS)"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"Y08559","properties":[{"key":"ProteinId","value":"CAA69860.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AL009126","properties":[{"key":"ProteinId","value":"CAB15680.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"D70063","properties":[{"key":"EntryName","value":"D70063"}]},{"database":"RefSeq","id":"NP_391544.1","properties":[{"key":"NucleotideSequenceId","value":"NC_000964.3"}]},{"database":"RefSeq","id":"WP_003227734.1","properties":[{"key":"NucleotideSequenceId","value":"NC_000964.3"}]},{"database":"PDB","id":"1XD7","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"2.30 A"},{"key":"Chains","value":"A=2-133"}]},{"database":"PDBsum","id":"1XD7","properties":[{"key":"Description","value":"-"}]},{"database":"AlphaFoldDB","id":"P71036","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P71036","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P71036","properties":[{"key":"Number of interactors","value":"16"}]},{"database":"STRING","id":"224308.BSU36630","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"224308-BSU36630","properties":[{"key":"Description","value":"-"}]},{"database":"DNASU","id":"936952","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"CAB15680","properties":[{"key":"ProteinId","value":"CAB15680"},{"key":"GeneId","value":"BSU_36630"}]},{"database":"GeneID","id":"936952","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"bsu:BSU36630","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|224308.179.peg.3964","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"eggNOG","id":"COG1959","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"InParanoid","id":"P71036","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"213028at2","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P71036","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"BSUB:BSU36630-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"EvolutionaryTrace","id":"P71036","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001570","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"AbasyAtlas","id":"P71036","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0003700","properties":[{"key":"GoTerm","value":"F:DNA-binding transcription factor activity"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0006355","properties":[{"key":"GoTerm","value":"P:regulation of DNA-templated transcription"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"FunFam","id":"1.10.10.10:FF:000138","properties":[{"key":"EntryName","value":"Rrf2 family transcriptional regulator"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.10.10","properties":[{"key":"EntryName","value":"Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR000944","properties":[{"key":"EntryName","value":"Tscrpt_reg_Rrf2"}]},{"database":"InterPro","id":"IPR036388","properties":[{"key":"EntryName","value":"WH-like_DNA-bd_sf"}]},{"database":"InterPro","id":"IPR036390","properties":[{"key":"EntryName","value":"WH_DNA-bd_sf"}]},{"database":"PANTHER","id":"PTHR33221:SF15","properties":[{"key":"EntryName","value":"HTH-TYPE TRANSCRIPTIONAL REGULATOR YWGB-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR33221","properties":[{"key":"EntryName","value":"WINGED HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, RRF2 FAMILY"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02082","properties":[{"key":"EntryName","value":"Rrf2"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF46785","properties":[{"key":"EntryName","value":"Winged helix' DNA-binding domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51197","properties":[{"key":"EntryName","value":"HTH_RRF2_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MINSRLAVAIHILSLISMDEKTSSEIIADSVNTNPVVVRRMISLLKKADILTSRAGVPGASLKKDPADISLLEVYRAVQKQEELFAVHENPNPKCPVGKKIQNALDETFESVQRAMENELASKSLKDVMNHLF","length":133,"molWeight":14711,"crc64":"6F46176B2603BF70","md5":"317BC157BB4116D601CE44DF927B2766"},"extraAttributes":{"countByFeatureType":{"Chain":1,"Domain":1,"DNA binding":1,"Helix":7,"Beta strand":3},"uniParcId":"UPI0000060B93"}}