{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P64620","secondaryAccessions":["P45764"],"uniProtkbId":"YHDU_ECOL6","entryAudit":{"firstPublicDate":"2004-10-11","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"2004-10-11","entryVersion":75,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)","taxonId":199310,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized protein YhdU"}}},"genes":[{"geneName":{"value":"yhdU"},"orderedLocusNames":[{"value":"c4029"}]}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Membrane","id":"SL-0162"},"topology":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Single-pass membrane protein","id":"SL-9904"}}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"AAN82469.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":59,"modifier":"EXACT"}},"description":"Uncharacterized protein YhdU","featureId":"PRO_0000169501"},{"type":"Transmembrane","location":{"start":{"value":6,"modifier":"EXACT"},"end":{"value":26,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}],"keywords":[{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"12471157","citationType":"journal article","authors":["Welch R.A.","Burland V.","Plunkett G. III","Redford P.","Roesch P.","Rasko D.","Buckles E.L.","Liou S.-R.","Boutin A.","Hackett J.","Stroud D.","Mayhew G.F.","Rose D.J.","Zhou S.","Schwartz D.C.","Perna N.T.","Mobley H.L.T.","Donnenberg M.S.","Blattner F.R."],"citationCrossReferences":[{"database":"PubMed","id":"12471157"},{"database":"DOI","id":"10.1073/pnas.252529799"}],"title":"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.","publicationDate":"2002","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"17020","lastPage":"17024","volume":"99"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"CFT073 / ATCC 700928 / UPEC","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AE014075","properties":[{"key":"ProteinId","value":"AAN82469.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_001295275.1","properties":[{"key":"NucleotideSequenceId","value":"NC_004431.1"}]},{"database":"AlphaFoldDB","id":"P64620","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P64620","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"199310.c4029","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"75173432","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecc:c4029","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG50331MQ","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"HOGENOM","id":"CLU_2914126_0_0_6","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001410","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"InterPro","id":"IPR022540","properties":[{"key":"EntryName","value":"DUF2556"}]},{"database":"Pfam","id":"PF10831","properties":[{"key":"EntryName","value":"DUF2556"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MIRKYWWLVVFAVFVFLFDTLLMQWIELLATETDKCRNMNSVNPLKLVNCDELNFQDRM","length":59,"molWeight":7204,"crc64":"4A7709CC9FE3FB86","md5":"105503EC0A857AE7F390413C9C7C874C"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1,"SEQUENCE CAUTION":1},"countByFeatureType":{"Chain":1,"Transmembrane":1},"uniParcId":"UPI000013B1FD"}}