{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P61997","secondaryAccessions":["P20297"],"uniProtkbId":"ENCP4_PYRWO","entryAudit":{"firstPublicDate":"2004-06-07","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2004-06-07","entryVersion":37,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Pyrococcus woesei","taxonId":2262,"lineage":["Archaea","Methanobacteriati","Methanobacteriota","Thermococci","Thermococcales","Thermococcaceae","Pyrococcus"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"34362927"}],"value":"Putative type 4B encapsulin shell protein"}},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"2165475"}],"value":"ORF b"}},{"fullName":{"value":"Uncharacterized protein in gap 3'region"}}]},"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"34362927"}],"value":"May be the encapsulin shell protein in a type 4 A-domain encapsulin nanocompartment system. Its cargo may be upstream glyceraldehyde-3-phosphate dehydrogenase (AC P61880)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"34362927"}],"value":"May self-assemble into facets and potentially into larger complexes"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"34362927"}],"value":"Encapsulin nanocompartment","id":"SL-0550"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"34362927"}],"value":"Belongs to the encapsulin family. Family 4B subfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":99,"modifier":"EXACT"}},"description":"Putative type 4B encapsulin shell protein","featureId":"PRO_0000184783"}],"keywords":[{"id":"KW-1284","category":"Cellular component","name":"Encapsulin nanocompartment"}],"references":[{"referenceNumber":1,"citation":{"id":"2165475","citationType":"journal article","authors":["Zwickl P.","Fabry S.","Bogedain C.","Haas A.","Hensel R."],"citationCrossReferences":[{"database":"PubMed","id":"2165475"},{"database":"DOI","id":"10.1128/jb.172.8.4329-4338.1990"}],"title":"Glyceraldehyde-3-phosphate dehydrogenase from the hyperthermophilic archaebacterium Pyrococcus woesei: characterization of the enzyme, cloning and sequencing of the gene, and expression in Escherichia coli.","publicationDate":"1990","journal":"J. Bacteriol.","firstPage":"4329","lastPage":"4338","volume":"172"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 49860 / DSM 3773 / JCM 8421 / Vul4","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"34362927","citationType":"journal article","authors":["Andreas M.P.","Giessen T.W."],"citationCrossReferences":[{"database":"PubMed","id":"34362927"},{"database":"DOI","id":"10.1038/s41467-021-25071-y"}],"title":"Large-scale computational discovery and analysis of virus-derived microbial nanocompartments.","publicationDate":"2021","journal":"Nat. Commun.","firstPage":"4748","lastPage":"4748","volume":"12"},"referencePositions":["PUTATIVE FUNCTION","SUBUNIT","PUTATIVE SUBCELLULAR LOCATION","CLASSIFICATION"]}],"uniProtKBCrossReferences":[{"database":"PIR","id":"S10654","properties":[{"key":"EntryName","value":"QQQYBW"}]},{"database":"RefSeq","id":"WP_011013014.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_AP042435.1"}]},{"database":"AlphaFoldDB","id":"P61997","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P61997","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"13301305","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"41713695","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0140737","properties":[{"key":"GoTerm","value":"C:encapsulin nanocompartment"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"Gene3D","id":"3.30.2320.10","properties":[{"key":"EntryName","value":"hypothetical protein PF0899 domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR014418","properties":[{"key":"EntryName","value":"ENCP4"}]},{"database":"InterPro","id":"IPR036216","properties":[{"key":"EntryName","value":"ENCP4_sf"}]},{"database":"NCBIfam","id":"NF041191","properties":[{"key":"EntryName","value":"encap_f4b"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF08967","properties":[{"key":"EntryName","value":"ENCP4"},{"key":"MatchStatus","value":"1"}]},{"database":"PIRSF","id":"PIRSF004604","properties":[{"key":"EntryName","value":"UCP004604"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF111057","properties":[{"key":"EntryName","value":"Hypothetical protein PF0899"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MENNNIMSQVKEIIEAAIKELEDDGFEPDIILAGPIFIRYLPEDVRLKVYEIEELGSDAIIADSKYLGQIKKAAKRISIDPLLQEKEWEKIIEEIPTQE","length":99,"molWeight":11386,"crc64":"4502157C0AB6755E","md5":"4CFED2EC958AC81AF379A287E907D949"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI000013B348"}}