{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P53218","secondaryAccessions":["D6VUG5"],"uniProtkbId":"POP6_YEAST","entryAudit":{"firstPublicDate":"1996-10-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1996-10-01","entryVersion":178,"sequenceVersion":1},"annotationScore":5.0,"organism":{"scientificName":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","commonName":"Baker's yeast","taxonId":559292,"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Saccharomycotina","Saccharomycetes","Saccharomycetales","Saccharomycetaceae","Saccharomyces"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Ribonucleases P/MRP protein subunit POP6"},"ecNumbers":[{"value":"3.1.26.5"}]},"alternativeNames":[{"fullName":{"value":"RNA-processing protein POP6"}},{"fullName":{"value":"RNases P/MRP 18.2 kDa subunit"}}]},"genes":[{"geneName":{"value":"POP6"},"orderedLocusNames":[{"value":"YGR030C"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9620854"}],"value":"Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP, which cleaves pre-rRNA sequences"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.","ecNumber":"3.1.26.5"}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"15637077"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"9620854"}],"value":"Component of nuclear RNase P and RNase MRP complexes. RNase P consists of an RNA moiety and at least 9 protein subunits including POP1, POP3, POP4, POP5, POP6, POP7, POP8, RPP1 and RPR2. RNase MRP complex consists of an RNA moiety and at least 10 protein subunits including POP1, POP3, POP4, POP5, POP6, POP7, POP8, RMP1, RPP1 and SNM1, many of which are shared with the RNase P complex"}],"commentType":"SUBUNIT"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"P53218","intActId":"EBI-13662"},"interactantTwo":{"uniProtKBAccession":"P41812","geneName":"POP1","intActId":"EBI-13621"},"numberOfExperiments":6,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"P53218","intActId":"EBI-13662"},"interactantTwo":{"uniProtKBAccession":"P38336","geneName":"POP4","intActId":"EBI-13646"},"numberOfExperiments":5,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"P53218","intActId":"EBI-13662"},"interactantTwo":{"uniProtKBAccession":"P28005","geneName":"POP5","intActId":"EBI-13654"},"numberOfExperiments":3,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"P53218","intActId":"EBI-13662"},"interactantTwo":{"uniProtKBAccession":"P38291","geneName":"POP7","intActId":"EBI-13670"},"numberOfExperiments":4,"organismDiffer":false},{"interactantOne":{"uniProtKBAccession":"P53218","intActId":"EBI-13662"},"interactantTwo":{"uniProtKBAccession":"P40571","geneName":"RPR2","intActId":"EBI-25408"},"numberOfExperiments":3,"organismDiffer":false}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14562095"}],"value":"Nucleus","id":"SL-0191"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14562106"}],"value":"Present with 3180 molecules/cell in log phase SD medium"}],"commentType":"MISCELLANEOUS"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":158,"modifier":"EXACT"}},"description":"Ribonucleases P/MRP protein subunit POP6","featureId":"PRO_0000058517"},{"type":"Coiled coil","location":{"start":{"value":51,"modifier":"EXACT"},"end":{"value":71,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Beta strand","location":{"start":{"value":4,"modifier":"EXACT"},"end":{"value":7,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Beta strand","location":{"start":{"value":10,"modifier":"EXACT"},"end":{"value":12,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Helix","location":{"start":{"value":19,"modifier":"EXACT"},"end":{"value":25,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Helix","location":{"start":{"value":26,"modifier":"EXACT"},"end":{"value":30,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Turn","location":{"start":{"value":31,"modifier":"EXACT"},"end":{"value":34,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Beta strand","location":{"start":{"value":37,"modifier":"EXACT"},"end":{"value":40,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Beta strand","location":{"start":{"value":42,"modifier":"EXACT"},"end":{"value":48,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Helix","location":{"start":{"value":55,"modifier":"EXACT"},"end":{"value":65,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Beta strand","location":{"start":{"value":68,"modifier":"EXACT"},"end":{"value":70,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"6W6V"}]},{"type":"Turn","location":{"start":{"value":71,"modifier":"EXACT"},"end":{"value":74,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Beta strand","location":{"start":{"value":76,"modifier":"EXACT"},"end":{"value":84,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Helix","location":{"start":{"value":85,"modifier":"EXACT"},"end":{"value":87,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Helix","location":{"start":{"value":88,"modifier":"EXACT"},"end":{"value":103,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Turn","location":{"start":{"value":104,"modifier":"EXACT"},"end":{"value":106,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Beta strand","location":{"start":{"value":110,"modifier":"EXACT"},"end":{"value":123,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Beta strand","location":{"start":{"value":125,"modifier":"EXACT"},"end":{"value":128,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C7A"}]},{"type":"Beta strand","location":{"start":{"value":130,"modifier":"EXACT"},"end":{"value":144,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]},{"type":"Beta strand","location":{"start":{"value":155,"modifier":"EXACT"},"end":{"value":157,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"7C79"}]}],"keywords":[{"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"id":"KW-0175","category":"Domain","name":"Coiled coil"},{"id":"KW-0378","category":"Molecular function","name":"Hydrolase"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0698","category":"Biological process","name":"rRNA processing"},{"id":"KW-0819","category":"Biological process","name":"tRNA processing"}],"references":[{"referenceNumber":1,"citation":{"id":"9290212","citationType":"journal article","authors":["Rieger M.","Brueckner M.","Schaefer M.","Mueller-Auer S."],"citationCrossReferences":[{"database":"PubMed","id":"9290212"},{"database":"DOI","id":"10.1002/(sici)1097-0061(19970915)13:11<1077::aid-yea152>3.0.co;2-y"}],"title":"Sequence analysis of 203 kilobases from Saccharomyces cerevisiae chromosome VII.","publicationDate":"1997","journal":"Yeast","firstPage":"1077","lastPage":"1090","volume":"13"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9169869","citationType":"journal article","authors":["Tettelin H.","Agostoni-Carbone M.L.","Albermann K.","Albers M.","Arroyo J.","Backes U.","Barreiros T.","Bertani I.","Bjourson A.J.","Brueckner M.","Bruschi C.V.","Carignani G.","Castagnoli L.","Cerdan E.","Clemente M.L.","Coblenz A.","Coglievina M.","Coissac E.","Defoor E.","Del Bino S.","Delius H.","Delneri D.","de Wergifosse P.","Dujon B.","Durand P.","Entian K.-D.","Eraso P.","Escribano V.","Fabiani L.","Fartmann B.","Feroli F.","Feuermann M.","Frontali L.","Garcia-Gonzalez M.","Garcia-Saez M.I.","Goffeau A.","Guerreiro P.","Hani J.","Hansen M.","Hebling U.","Hernandez K.","Heumann K.","Hilger F.","Hofmann B.","Indge K.J.","James C.M.","Klima R.","Koetter P.","Kramer B.","Kramer W.","Lauquin G.","Leuther H.","Louis E.J.","Maillier E.","Marconi A.","Martegani E.","Mazon M.J.","Mazzoni C.","McReynolds A.D.K.","Melchioretto P.","Mewes H.-W.","Minenkova O.","Mueller-Auer S.","Nawrocki A.","Netter P.","Neu R.","Nombela C.","Oliver S.G.","Panzeri L.","Paoluzi S.","Plevani P.","Portetelle D.","Portillo F.","Potier S.","Purnelle B.","Rieger M.","Riles L.","Rinaldi T.","Robben J.","Rodrigues-Pousada C.","Rodriguez-Belmonte E.","Rodriguez-Torres A.M.","Rose M.","Ruzzi M.","Saliola M.","Sanchez-Perez M.","Schaefer B.","Schaefer M.","Scharfe M.","Schmidheini T.","Schreer A.","Skala J.","Souciet J.-L.","Steensma H.Y.","Talla E.","Thierry A.","Vandenbol M.","van der Aart Q.J.M.","Van Dyck L.","Vanoni M.","Verhasselt P.","Voet M.","Volckaert G.","Wambutt R.","Watson M.D.","Weber N.","Wedler E.","Wedler H.","Wipfli P.","Wolf K.","Wright L.F.","Zaccaria P.","Zimmermann M.","Zollner A.","Kleine K."],"citationCrossReferences":[{"database":"PubMed","id":"9169869"},{"database":"DOI","id":"10.1038/387s081"}],"title":"The nucleotide sequence of Saccharomyces cerevisiae chromosome VII.","publicationDate":"1997","journal":"Nature","firstPage":"81","lastPage":"84","volume":"387"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"24374639","citationType":"journal article","authors":["Engel S.R.","Dietrich F.S.","Fisk D.G.","Binkley G.","Balakrishnan R.","Costanzo M.C.","Dwight S.S.","Hitz B.C.","Karra K.","Nash R.S.","Weng S.","Wong E.D.","Lloyd P.","Skrzypek M.S.","Miyasato S.R.","Simison M.","Cherry J.M."],"citationCrossReferences":[{"database":"PubMed","id":"24374639"},{"database":"DOI","id":"10.1534/g3.113.008995"}],"title":"The reference genome sequence of Saccharomyces cerevisiae: Then and now.","publicationDate":"2014","journal":"G3 (Bethesda)","firstPage":"389","lastPage":"398","volume":"4"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"17322287","citationType":"journal article","authors":["Hu Y.","Rolfs A.","Bhullar B.","Murthy T.V.S.","Zhu C.","Berger M.F.","Camargo A.A.","Kelley F.","McCarron S.","Jepson D.","Richardson A.","Raphael J.","Moreira D.","Taycher E.","Zuo D.","Mohr S.","Kane M.F.","Williamson J.","Simpson A.J.G.","Bulyk M.L.","Harlow E.","Marsischky G.","Kolodner R.D.","LaBaer J."],"citationCrossReferences":[{"database":"PubMed","id":"17322287"},{"database":"DOI","id":"10.1101/gr.6037607"}],"title":"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.","publicationDate":"2007","journal":"Genome Res.","firstPage":"536","lastPage":"543","volume":"17"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"9620854","citationType":"journal article","authors":["Chamberlain J.R.","Lee Y.","Lane W.S.","Engelke D.R."],"citationCrossReferences":[{"database":"PubMed","id":"9620854"},{"database":"DOI","id":"10.1101/gad.12.11.1678"}],"title":"Purification and characterization of the nuclear RNase P holoenzyme complex reveals extensive subunit overlap with RNase MRP.","publicationDate":"1998","journal":"Genes Dev.","firstPage":"1678","lastPage":"1690","volume":"12"},"referencePositions":["FUNCTION","IDENTIFICATION IN THE RNASE P COMPLEX BY MASS SPECTROMETRY"]},{"referenceNumber":6,"citation":{"id":"14690591","citationType":"journal article","authors":["Hazbun T.R.","Malmstroem L.","Anderson S.","Graczyk B.J.","Fox B.","Riffle M.","Sundin B.A.","Aranda J.D.","McDonald W.H.","Chiu C.-H.","Snydsman B.E.","Bradley P.","Muller E.G.D.","Fields S.","Baker D.","Yates J.R. III","Davis T.N."],"citationCrossReferences":[{"database":"PubMed","id":"14690591"},{"database":"DOI","id":"10.1016/s1097-2765(03)00476-3"}],"title":"Assigning function to yeast proteins by integration of technologies.","publicationDate":"2003","journal":"Mol. Cell","firstPage":"1353","lastPage":"1365","volume":"12"},"referencePositions":["IDENTIFICATION BY MASS SPECTROMETRY"]},{"referenceNumber":7,"citation":{"id":"14562095","citationType":"journal article","authors":["Huh W.-K.","Falvo J.V.","Gerke L.C.","Carroll A.S.","Howson R.W.","Weissman J.S.","O'Shea E.K."],"citationCrossReferences":[{"database":"PubMed","id":"14562095"},{"database":"DOI","id":"10.1038/nature02026"}],"title":"Global analysis of protein localization in budding yeast.","publicationDate":"2003","journal":"Nature","firstPage":"686","lastPage":"691","volume":"425"},"referencePositions":["SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]"]},{"referenceNumber":8,"citation":{"id":"14562106","citationType":"journal article","authors":["Ghaemmaghami S.","Huh W.-K.","Bower K.","Howson R.W.","Belle A.","Dephoure N.","O'Shea E.K.","Weissman J.S."],"citationCrossReferences":[{"database":"PubMed","id":"14562106"},{"database":"DOI","id":"10.1038/nature02046"}],"title":"Global analysis of protein expression in yeast.","publicationDate":"2003","journal":"Nature","firstPage":"737","lastPage":"741","volume":"425"},"referencePositions":["LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]"]},{"referenceNumber":9,"citation":{"id":"15637077","citationType":"journal article","authors":["Salinas K.","Wierzbicki S.","Zhou L.","Schmitt M.E."],"citationCrossReferences":[{"database":"PubMed","id":"15637077"},{"database":"DOI","id":"10.1074/jbc.m409568200"}],"title":"Characterization and purification of Saccharomyces cerevisiae RNase MRP reveals a new unique protein component.","publicationDate":"2005","journal":"J. Biol. Chem.","firstPage":"11352","lastPage":"11360","volume":"280"},"referencePositions":["IDENTIFICATION IN THE RNASE MRP COMPLEX BY MASS SPECTROMETRY"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"Z72815","properties":[{"key":"ProteinId","value":"CAA97018.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY558324","properties":[{"key":"ProteinId","value":"AAS56650.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BK006941","properties":[{"key":"ProteinId","value":"DAA08126.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"S64321","properties":[{"key":"EntryName","value":"S64321"}]},{"database":"RefSeq","id":"NP_011544.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001181159.1"}]},{"database":"PDB","id":"3IAB","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"2.70 A"},{"key":"Chains","value":"A=1-158"}]},{"database":"PDB","id":"6AGB","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"3.48 A"},{"key":"Chains","value":"F=1-158"}]},{"database":"PDB","id":"6AH3","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"3.48 A"},{"key":"Chains","value":"F=1-158"}]},{"database":"PDB","id":"6W6V","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"3.00 A"},{"key":"Chains","value":"F=1-158"}]},{"database":"PDB","id":"7C79","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"2.50 A"},{"key":"Chains","value":"F=1-158"}]},{"database":"PDB","id":"7C7A","properties":[{"key":"Method","value":"EM"},{"key":"Resolution","value":"2.80 A"},{"key":"Chains","value":"F=1-158"}]},{"database":"PDBsum","id":"3IAB","properties":[{"key":"Description","value":"-"}]},{"database":"PDBsum","id":"6AGB","properties":[{"key":"Description","value":"-"}]},{"database":"PDBsum","id":"6AH3","properties":[{"key":"Description","value":"-"}]},{"database":"PDBsum","id":"6W6V","properties":[{"key":"Description","value":"-"}]},{"database":"PDBsum","id":"7C79","properties":[{"key":"Description","value":"-"}]},{"database":"PDBsum","id":"7C7A","properties":[{"key":"Description","value":"-"}]},{"database":"AlphaFoldDB","id":"P53218","properties":[{"key":"Description","value":"-"}]},{"database":"EMDB","id":"EMD-21564","properties":[{"key":"Description","value":"-"}]},{"database":"EMDB","id":"EMD-30296","properties":[{"key":"Description","value":"-"}]},{"database":"EMDB","id":"EMD-30297","properties":[{"key":"Description","value":"-"}]},{"database":"EMDB","id":"EMD-55321","properties":[{"key":"Description","value":"-"}]},{"database":"EMDB","id":"EMD-9616","properties":[{"key":"Description","value":"-"}]},{"database":"EMDB","id":"EMD-9622","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P53218","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"33275","properties":[{"key":"Interactions","value":"38"}]},{"database":"ComplexPortal","id":"CPX-1873","properties":[{"key":"EntryName","value":"Nucleolar ribonuclease P complex"}]},{"database":"ComplexPortal","id":"CPX-3284","properties":[{"key":"EntryName","value":"Ribonuclease MRP complex"}]},{"database":"DIP","id":"DIP-6775N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P53218","properties":[{"key":"Number of interactors","value":"123"}]},{"database":"IntAct","id":"P53218","properties":[{"key":"Interactions","value":"16"}]},{"database":"MINT","id":"P53218","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"4932.YGR030C","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"4932-YGR030C","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"P53218","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblFungi","id":"YGR030C_mRNA","properties":[{"key":"ProteinId","value":"YGR030C"},{"key":"GeneId","value":"YGR030C"}]},{"database":"GeneID","id":"852918","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"sce:YGR030C","properties":[{"key":"Description","value":"-"}]},{"database":"AGR","id":"SGD:S000003262","properties":[{"key":"Description","value":"-"}]},{"database":"SGD","id":"S000003262","properties":[{"key":"GeneName","value":"POP6"}]},{"database":"VEuPathDB","id":"FungiDB:YGR030C","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502S7W4","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_115485_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P53218","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"KVETHNE","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"4033941at2759","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"YEAST:YGR030C-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"BRENDA","id":"3.1.26.5","properties":[{"key":"OrganismId","value":"984"}]},{"database":"BioGRID-ORCS","id":"852918","properties":[{"key":"hits","value":"0 hits in 10 CRISPR screens"}]},{"database":"CD-CODE","id":"7CAF9006","properties":[{"key":"EntryName","value":"Tam body"}]},{"database":"EvolutionaryTrace","id":"P53218","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:P53218","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000002311","properties":[{"key":"Component","value":"Chromosome VII"}]},{"database":"RNAct","id":"P53218","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"22932476"}]},{"database":"GO","id":"GO:0005655","properties":[{"key":"GoTerm","value":"C:nucleolar ribonuclease P complex"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"9620854"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"22932476"}]},{"database":"GO","id":"GO:0000172","properties":[{"key":"GoTerm","value":"C:ribonuclease MRP complex"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"9620854"}]},{"database":"GO","id":"GO:0005697","properties":[{"key":"GoTerm","value":"C:telomerase holoenzyme complex"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"27156450"}]},{"database":"GO","id":"GO:0004526","properties":[{"key":"GoTerm","value":"F:ribonuclease P activity"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-EC"}]},{"database":"GO","id":"GO:0003723","properties":[{"key":"GoTerm","value":"F:RNA binding"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"26135751"}]},{"database":"GO","id":"GO:0042134","properties":[{"key":"GoTerm","value":"F:rRNA primary transcript binding"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"17881380"}]},{"database":"GO","id":"GO:0034965","properties":[{"key":"GoTerm","value":"P:intronic box C/D snoRNA processing"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"18713869"}]},{"database":"GO","id":"GO:0000460","properties":[{"key":"GoTerm","value":"P:maturation of 5.8S rRNA"},{"key":"GoEvidenceType","value":"IDA:ComplexPortal"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"32586950"}]},{"database":"GO","id":"GO:0000294","properties":[{"key":"GoTerm","value":"P:nuclear-transcribed mRNA catabolic process, RNase MRP-dependent"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"14729943"}]},{"database":"GO","id":"GO:0006364","properties":[{"key":"GoTerm","value":"P:rRNA processing"},{"key":"GoEvidenceType","value":"IMP:SGD"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"9620854"}]},{"database":"GO","id":"GO:0001682","properties":[{"key":"GoTerm","value":"P:tRNA 5'-leader removal"},{"key":"GoEvidenceType","value":"IDA:ComplexPortal"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"22167472"}]},{"database":"GO","id":"GO:0008033","properties":[{"key":"GoTerm","value":"P:tRNA processing"},{"key":"GoEvidenceType","value":"IMP:SGD"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"9620854"}]},{"database":"InterPro","id":"IPR002775","properties":[{"key":"EntryName","value":"DNA/RNA-bd_Alba-like"}]},{"database":"Pfam","id":"PF01918","properties":[{"key":"EntryName","value":"Alba"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MINGVYYNEISRDLDISSSTQCLRFLKETVIPSLANNGNNSTSIQYHGISKNDNIKKSVNKLDKQINMADRSLGLQQVVCIFSYGPHIQKMLSILEIFKKGYIKNNKKIYQWNKLTSFDIKREGRNELQEERLKVPILVTLVSDSEIIDLNLHSFTKQ","length":158,"molWeight":18210,"crc64":"6C27A73FAD521181","md5":"3BAA8AE1CEC0ABA0794005B18F5BE817"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"SUBUNIT":1,"INTERACTION":5,"SUBCELLULAR LOCATION":1,"MISCELLANEOUS":1},"countByFeatureType":{"Chain":1,"Coiled coil":1,"Beta strand":10,"Helix":5,"Turn":3},"uniParcId":"UPI0000131F3A"}}