{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P49847","secondaryAccessions":["Q961B6","Q9VW16"],"uniProtkbId":"TAF6_DROME","entryAudit":{"firstPublicDate":"1996-10-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2003-01-27","entryVersion":201,"sequenceVersion":2},"annotationScore":5.0,"organism":{"scientificName":"Drosophila melanogaster","commonName":"Fruit fly","taxonId":7227,"lineage":["Eukaryota","Metazoa","Ecdysozoa","Arthropoda","Altocrustacea","Allotriocarida","Hexapoda","Insecta","Pterygota","Neoptera","Eumetabola","Endopterygota","Aparaglossata","Panorpida","Diptera","Brachycera","Muscomorpha","Ephydroidea","Drosophilidae","Drosophila","Sophophora"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Transcription initiation factor TFIID subunit 6"}},"alternativeNames":[{"fullName":{"value":"TAFII-60"}},{"fullName":{"value":"TAFII-62"}},{"fullName":{"value":"Transcription initiation factor TFIID 62 kDa subunit"},"shortNames":[{"value":"p62"}]}]},"genes":[{"geneName":{"value":"Taf6"},"synonyms":[{"value":"Taf60"}],"orfNames":[{"value":"CG32211"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"8262073"}],"value":"TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"8262073"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"8598927"}],"value":"Belongs to the TFIID complex which is composed of TATA binding protein (Tbp) and a number of TBP-associated factors (TAFs) (PubMed:8262073, PubMed:8598927). Taf9 and Taf6 exist as a heterotetramer (PubMed:8262073). Interacts with Taf1 (PubMed:8598927)"}],"commentType":"SUBUNIT"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"P49847","intActId":"EBI-136204"},"interactantTwo":{"uniProtKBAccession":"Q27272","geneName":"Taf9","intActId":"EBI-174260"},"numberOfExperiments":2,"organismDiffer":false}]},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"value":"Nucleus","id":"SL-0191"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the TAF6 family"}],"commentType":"SIMILARITY"},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"AAA16536.1","evidences":[{"evidenceCode":"ECO:0000305"}]},{"commentType":"SEQUENCE CAUTION","sequenceCautionType":"Erroneous initiation","sequence":"AAC46480.1","evidences":[{"evidenceCode":"ECO:0000305"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":606,"modifier":"EXACT"}},"description":"Transcription initiation factor TFIID subunit 6","featureId":"PRO_0000118877"},{"type":"Modified residue","location":{"start":{"value":546,"modifier":"EXACT"},"end":{"value":546,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18327897"}]},{"type":"Modified residue","location":{"start":{"value":547,"modifier":"EXACT"},"end":{"value":547,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18327897"}]},{"type":"Modified residue","location":{"start":{"value":550,"modifier":"EXACT"},"end":{"value":550,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"18327897"}]},{"type":"Sequence conflict","location":{"start":{"value":3,"modifier":"EXACT"},"end":{"value":3,"modifier":"EXACT"}},"description":"in Ref. 4; AA sequence","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"G","alternativeSequences":["K"]}},{"type":"Sequence conflict","location":{"start":{"value":101,"modifier":"EXACT"},"end":{"value":101,"modifier":"EXACT"}},"description":"in Ref. 5; AAA16536","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"F","alternativeSequences":["L"]}},{"type":"Sequence conflict","location":{"start":{"value":582,"modifier":"EXACT"},"end":{"value":582,"modifier":"EXACT"}},"description":"in Ref. 4; AAC46480 and 5; AAA16536","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"D","alternativeSequences":["E"]}},{"type":"Helix","location":{"start":{"value":23,"modifier":"EXACT"},"end":{"value":32,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TAF"}]},{"type":"Helix","location":{"start":{"value":40,"modifier":"EXACT"},"end":{"value":67,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TAF"}]},{"type":"Beta strand","location":{"start":{"value":71,"modifier":"EXACT"},"end":{"value":73,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TAF"}]},{"type":"Helix","location":{"start":{"value":75,"modifier":"EXACT"},"end":{"value":82,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TAF"}]}],"keywords":[{"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"id":"KW-0903","category":"Technical term","name":"Direct protein sequencing"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"10731132","citationType":"journal article","authors":["Adams M.D.","Celniker S.E.","Holt R.A.","Evans C.A.","Gocayne J.D.","Amanatides P.G.","Scherer S.E.","Li P.W.","Hoskins R.A.","Galle R.F.","George R.A.","Lewis S.E.","Richards S.","Ashburner M.","Henderson S.N.","Sutton G.G.","Wortman J.R.","Yandell M.D.","Zhang Q.","Chen L.X.","Brandon R.C.","Rogers Y.-H.C.","Blazej R.G.","Champe M.","Pfeiffer B.D.","Wan K.H.","Doyle C.","Baxter E.G.","Helt G.","Nelson C.R.","Miklos G.L.G.","Abril J.F.","Agbayani A.","An H.-J.","Andrews-Pfannkoch C.","Baldwin D.","Ballew R.M.","Basu A.","Baxendale J.","Bayraktaroglu L.","Beasley E.M.","Beeson K.Y.","Benos P.V.","Berman B.P.","Bhandari D.","Bolshakov S.","Borkova D.","Botchan M.R.","Bouck J.","Brokstein P.","Brottier P.","Burtis K.C.","Busam D.A.","Butler H.","Cadieu E.","Center A.","Chandra I.","Cherry J.M.","Cawley S.","Dahlke C.","Davenport L.B.","Davies P.","de Pablos B.","Delcher A.","Deng Z.","Mays A.D.","Dew I.","Dietz S.M.","Dodson K.","Doup L.E.","Downes M.","Dugan-Rocha S.","Dunkov B.C.","Dunn P.","Durbin K.J.","Evangelista C.C.","Ferraz C.","Ferriera S.","Fleischmann W.","Fosler C.","Gabrielian A.E.","Garg N.S.","Gelbart W.M.","Glasser K.","Glodek A.","Gong F.","Gorrell J.H.","Gu Z.","Guan P.","Harris M.","Harris N.L.","Harvey D.A.","Heiman T.J.","Hernandez J.R.","Houck J.","Hostin D.","Houston K.A.","Howland T.J.","Wei M.-H.","Ibegwam C.","Jalali M.","Kalush F.","Karpen G.H.","Ke Z.","Kennison J.A.","Ketchum K.A.","Kimmel B.E.","Kodira C.D.","Kraft C.L.","Kravitz S.","Kulp D.","Lai Z.","Lasko P.","Lei Y.","Levitsky A.A.","Li J.H.","Li Z.","Liang Y.","Lin X.","Liu X.","Mattei B.","McIntosh T.C.","McLeod M.P.","McPherson D.","Merkulov G.","Milshina N.V.","Mobarry C.","Morris J.","Moshrefi A.","Mount S.M.","Moy M.","Murphy B.","Murphy L.","Muzny D.M.","Nelson D.L.","Nelson D.R.","Nelson K.A.","Nixon K.","Nusskern D.R.","Pacleb J.M.","Palazzolo M.","Pittman G.S.","Pan S.","Pollard J.","Puri V.","Reese M.G.","Reinert K.","Remington K.","Saunders R.D.C.","Scheeler F.","Shen H.","Shue B.C.","Siden-Kiamos I.","Simpson M.","Skupski M.P.","Smith T.J.","Spier E.","Spradling A.C.","Stapleton M.","Strong R.","Sun E.","Svirskas R.","Tector C.","Turner R.","Venter E.","Wang A.H.","Wang X.","Wang Z.-Y.","Wassarman D.A.","Weinstock G.M.","Weissenbach J.","Williams S.M.","Woodage T.","Worley K.C.","Wu D.","Yang S.","Yao Q.A.","Ye J.","Yeh R.-F.","Zaveri J.S.","Zhan M.","Zhang G.","Zhao Q.","Zheng L.","Zheng X.H.","Zhong F.N.","Zhong W.","Zhou X.","Zhu S.C.","Zhu X.","Smith H.O.","Gibbs R.A.","Myers E.W.","Rubin G.M.","Venter J.C."],"citationCrossReferences":[{"database":"PubMed","id":"10731132"},{"database":"DOI","id":"10.1126/science.287.5461.2185"}],"title":"The genome sequence of Drosophila melanogaster.","publicationDate":"2000","journal":"Science","firstPage":"2185","lastPage":"2195","volume":"287"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"Berkeley","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"12537572","citationType":"journal article","authors":["Misra S.","Crosby M.A.","Mungall C.J.","Matthews B.B.","Campbell K.S.","Hradecky P.","Huang Y.","Kaminker J.S.","Millburn G.H.","Prochnik S.E.","Smith C.D.","Tupy J.L.","Whitfield E.J.","Bayraktaroglu L.","Berman B.P.","Bettencourt B.R.","Celniker S.E.","de Grey A.D.N.J.","Drysdale R.A.","Harris N.L.","Richter J.","Russo S.","Schroeder A.J.","Shu S.Q.","Stapleton M.","Yamada C.","Ashburner M.","Gelbart W.M.","Rubin G.M.","Lewis S.E."],"citationCrossReferences":[{"database":"PubMed","id":"12537572"},{"database":"DOI","id":"10.1186/gb-2002-3-12-research0083"}],"title":"Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.","publicationDate":"2002","journal":"Genome Biol.","firstPage":"RESEARCH0083.1","lastPage":"RESEARCH0083.22","volume":"3"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"Berkeley","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"12537569","citationType":"journal article","authors":["Stapleton M.","Carlson J.W.","Brokstein P.","Yu C.","Champe M.","George R.A.","Guarin H.","Kronmiller B.","Pacleb J.M.","Park S.","Wan K.H.","Rubin G.M.","Celniker S.E."],"citationCrossReferences":[{"database":"PubMed","id":"12537569"},{"database":"DOI","id":"10.1186/gb-2002-3-12-research0080"}],"title":"A Drosophila full-length cDNA resource.","publicationDate":"2002","journal":"Genome Biol.","firstPage":"RESEARCH0080.1","lastPage":"RESEARCH0080.8","volume":"3"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]"],"referenceComments":[{"value":"Berkeley","type":"STRAIN"},{"value":"Embryo","type":"TISSUE"}]},{"referenceNumber":4,"citation":{"id":"7545910","citationType":"journal article","authors":["Kokubo T.","Gong D.-W.","Wootton J.C.","Horikoshi M.","Roeder R.G.","Nakatani Y."],"citationCrossReferences":[{"database":"PubMed","id":"7545910"},{"database":"DOI","id":"10.1038/367484a0"}],"title":"Molecular cloning of Drosophila TFIID subunits.","publicationDate":"1994","journal":"Nature","firstPage":"484","lastPage":"487","volume":"367"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA] OF 3-606","PARTIAL PROTEIN SEQUENCE"]},{"referenceNumber":5,"citation":{"id":"8262073","citationType":"journal article","authors":["Weinzierl R.O.","Ruppert S.","Dynlacht B.D.","Tanese N.","Tjian R."],"citationCrossReferences":[{"database":"PubMed","id":"8262073"},{"database":"DOI","id":"10.1002/j.1460-2075.1993.tb06226.x"}],"title":"Cloning and expression of Drosophila TAFII60 and human TAFII70 reveal conserved interactions with other subunits of TFIID.","publicationDate":"1993","journal":"EMBO J.","firstPage":"5303","lastPage":"5309","volume":"12"},"referencePositions":["NUCLEOTIDE SEQUENCE [MRNA] OF 7-606","PARTIAL PROTEIN SEQUENCE","FUNCTION","INTERACTION WITH TAF1"],"referenceComments":[{"value":"Oregon-R","type":"STRAIN"}]},{"referenceNumber":6,"citation":{"id":"18327897","citationType":"journal article","authors":["Zhai B.","Villen J.","Beausoleil S.A.","Mintseris J.","Gygi S.P."],"citationCrossReferences":[{"database":"PubMed","id":"18327897"},{"database":"DOI","id":"10.1021/pr700696a"}],"title":"Phosphoproteome analysis of Drosophila melanogaster embryos.","publicationDate":"2008","journal":"J. Proteome Res.","firstPage":"1675","lastPage":"1682","volume":"7"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-546; SER-547 AND SER-550","IDENTIFICATION BY MASS SPECTROMETRY"],"referenceComments":[{"value":"Embryo","type":"TISSUE"}]},{"referenceNumber":7,"citation":{"id":"8598927","citationType":"journal article","authors":["Xie X.","Kokubo T.","Cohen S.L.","Mirza U.A.","Hoffmann A.","Chait B.T.","Roeder R.G.","Nakatani Y.","Burley S.K."],"citationCrossReferences":[{"database":"PubMed","id":"8598927"},{"database":"DOI","id":"10.1038/380316a0"}],"title":"Structural similarity between TAFs and the heterotetrameric core of the histone octamer.","publicationDate":"1996","journal":"Nature","firstPage":"316","lastPage":"322","volume":"380"},"referencePositions":["X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 15-84","INTERACTION WITH TAF9"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AE014296","properties":[{"key":"ProteinId","value":"AAF49139.2"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY051702","properties":[{"key":"ProteinId","value":"AAK93126.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"U06459","properties":[{"key":"ProteinId","value":"AAC46480.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"EMBL","id":"L25443","properties":[{"key":"ProteinId","value":"AAA16536.1"},{"key":"Status","value":"ALT_INIT"},{"key":"MoleculeType","value":"mRNA"}]},{"database":"RefSeq","id":"NP_524161.2","properties":[{"key":"NucleotideSequenceId","value":"NM_079437.4"}]},{"database":"PDB","id":"1TAF","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"2.00 A"},{"key":"Chains","value":"B=15-84"}]},{"database":"PDBsum","id":"1TAF","properties":[{"key":"Description","value":"-"}]},{"database":"AlphaFoldDB","id":"P49847","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P49847","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"65404","properties":[{"key":"Interactions","value":"34"}]},{"database":"DIP","id":"DIP-778N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P49847","properties":[{"key":"Number of interactors","value":"2147"}]},{"database":"IntAct","id":"P49847","properties":[{"key":"Interactions","value":"7"}]},{"database":"STRING","id":"7227.FBpp0074709","properties":[{"key":"Description","value":"-"}]},{"database":"GlyGen","id":"P49847","properties":[{"key":"glycosylation","value":"4 sites, 1 O-linked glycan (3 sites)"}]},{"database":"iPTMnet","id":"P49847","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"7227-FBpp0074709","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"P49847","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblMetazoa","id":"FBtr0074941","properties":[{"key":"ProteinId","value":"FBpp0074709"},{"key":"GeneId","value":"FBgn0010417"}]},{"database":"GeneID","id":"40134","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"dme:Dmel_CG32211","properties":[{"key":"Description","value":"-"}]},{"database":"AGR","id":"FB:FBgn0010417","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"6878","properties":[{"key":"Description","value":"-"}]},{"database":"FlyBase","id":"FBgn0010417","properties":[{"key":"GeneName","value":"Taf6"}]},{"database":"VEuPathDB","id":"VectorBase:FBgn0010417","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG2549","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"InParanoid","id":"P49847","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"MPEETCQ","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"361039at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P49847","properties":[{"key":"Description","value":"-"}]},{"database":"Reactome","id":"R-DME-674695","properties":[{"key":"PathwayName","value":"RNA Polymerase II Pre-transcription Events"}]},{"database":"Reactome","id":"R-DME-6804756","properties":[{"key":"PathwayName","value":"Regulation of TP53 Activity through Phosphorylation"}]},{"database":"Reactome","id":"R-DME-6807505","properties":[{"key":"PathwayName","value":"RNA polymerase II transcribes snRNA genes"}]},{"database":"Reactome","id":"R-DME-73776","properties":[{"key":"PathwayName","value":"RNA Polymerase II Promoter Escape"}]},{"database":"Reactome","id":"R-DME-73779","properties":[{"key":"PathwayName","value":"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening"}]},{"database":"Reactome","id":"R-DME-75953","properties":[{"key":"PathwayName","value":"RNA Polymerase II Transcription Initiation"}]},{"database":"Reactome","id":"R-DME-76042","properties":[{"key":"PathwayName","value":"RNA Polymerase II Transcription Initiation And Promoter Clearance"}]},{"database":"SignaLink","id":"P49847","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID-ORCS","id":"40134","properties":[{"key":"hits","value":"1 hit in 1 CRISPR screen"}]},{"database":"EvolutionaryTrace","id":"P49847","properties":[{"key":"Description","value":"-"}]},{"database":"GenomeRNAi","id":"40134","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:P49847","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000803","properties":[{"key":"Component","value":"Chromosome 3L"}]},{"database":"Bgee","id":"FBgn0010417","properties":[{"key":"ExpressionPatterns","value":"Expressed in T neuron T4b (Drosophila) in embryonic/larval optic lobe (Drosophila) and 94 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"P49847","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"16895980"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"16980620"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"7664336"}]},{"database":"GO","id":"GO:0000124","properties":[{"key":"GoTerm","value":"C:SAGA complex"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0046695","properties":[{"key":"GoTerm","value":"C:SLIK (SAGA-like) complex"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0005669","properties":[{"key":"GoTerm","value":"C:transcription factor TFIID complex"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"7664336"}]},{"database":"GO","id":"GO:0046982","properties":[{"key":"GoTerm","value":"F:protein heterodimerization activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0016251","properties":[{"key":"GoTerm","value":"F:RNA polymerase II general transcription initiation factor activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0003713","properties":[{"key":"GoTerm","value":"F:transcription coactivator activity"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0051123","properties":[{"key":"GoTerm","value":"P:RNA polymerase II preinitiation complex assembly"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0006366","properties":[{"key":"GoTerm","value":"P:transcription by RNA polymerase II"},{"key":"GoEvidenceType","value":"IDA:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"7664336"}]},{"database":"GO","id":"GO:0006367","properties":[{"key":"GoTerm","value":"P:transcription initiation at RNA polymerase II promoter"},{"key":"GoEvidenceType","value":"ISS:FlyBase"}],"evidences":[{"evidenceCode":"ECO:0000250","source":"PubMed","id":"10908585"}]},{"database":"CDD","id":"cd22931","properties":[{"key":"EntryName","value":"HFD_TAF6"},{"key":"MatchStatus","value":"1"}]},{"database":"CDD","id":"cd08050","properties":[{"key":"EntryName","value":"TAF6C"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.20.10:FF:000030","properties":[{"key":"EntryName","value":"Transcription initiation factor TFIID subunit 6"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.25.40.770:FF:000001","properties":[{"key":"EntryName","value":"Transcription initiation factor TFIID subunit 6"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.20.10","properties":[{"key":"EntryName","value":"Histone, subunit A"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.25.40.770","properties":[{"key":"EntryName","value":"TAF6, C-terminal HEAT repeat domain"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR016024","properties":[{"key":"EntryName","value":"ARM-type_fold"}]},{"database":"InterPro","id":"IPR009072","properties":[{"key":"EntryName","value":"Histone-fold"}]},{"database":"InterPro","id":"IPR037796","properties":[{"key":"EntryName","value":"TAF6"}]},{"database":"InterPro","id":"IPR011442","properties":[{"key":"EntryName","value":"TAF6_C"}]},{"database":"InterPro","id":"IPR046344","properties":[{"key":"EntryName","value":"TAF6_C_sf"}]},{"database":"InterPro","id":"IPR004823","properties":[{"key":"EntryName","value":"TAF_TATA-bd_Histone-like_dom"}]},{"database":"PANTHER","id":"PTHR10221","properties":[{"key":"EntryName","value":"TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10221:SF9","properties":[{"key":"EntryName","value":"TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF02969","properties":[{"key":"EntryName","value":"TAF"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07571","properties":[{"key":"EntryName","value":"TAF6_C"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00803","properties":[{"key":"EntryName","value":"TAF"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF48371","properties":[{"key":"EntryName","value":"ARM repeat"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF47113","properties":[{"key":"EntryName","value":"Histone-fold"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSGKPSKPSSPSSSMLYGSSISAESMKVIAESIGVGSLSDDAAKELAEDVSIKLKRIVQDAAKFMNHAKRQKLSVRDIDMSLKVRNVEPQYGFVAKDFIPFRFASGGGRELHFTEDKEIDLGEITSTNSVKIPLDLTLRSHWFVVEGVQPTVPENPPPLSKDSQLLDSVNPVIKMDQGLNKDAAGKPTTGKIHKLKNVETIHVKQLATHELSVEQQLYYKEITEACVGSDEPRRGEALQSLGSDPGLHEMLPRMCTFIAEGVKVNVVQNNLALLIYLMRMVRALLDNPSLFLEKYLHELIPSVMTCIVSKQLCMRPELDNHWALRDFASRLMAQICKNFNTLTNNLQTRVTRIFSKALQNDKTHLSSLYGSIAGLSELGGEVIKVFIIPRLKFISERIEPHLLGTSISNTDKTAAGHIRAMLQKCCPPILRQMRSAPDTAEDYKNDFGFLGPSLCQAVVKVRNAPASSIVTLSSNTINTAPITSAAQTATTIGRVSMPTTQRQGSPGVSSLPQIRAIQANQPAQKFVIVTQNSPQQGQAKVVRRGSSPHSVVLSAASNAASASNSNSSSSGSLLAAAQRSSDNVCVIAGSEAPAVDGITVQSFRAS","length":606,"molWeight":65654,"crc64":"9D93C3496A23C0A3","md5":"390A32B35746666B0DAED379A2A68F6F"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"INTERACTION":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1,"SEQUENCE CAUTION":2},"countByFeatureType":{"Chain":1,"Modified residue":3,"Sequence conflict":3,"Helix":3,"Beta strand":1},"uniParcId":"UPI00001247CA"}}