{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P42947","secondaryAccessions":["D6VW77"],"uniProtkbId":"YJK7_YEAST","entryAudit":{"firstPublicDate":"1995-11-01","lastAnnotationUpdateDate":"2026-06-10","lastSequenceUpdateDate":"1995-11-01","entryVersion":145,"sequenceVersion":1},"annotationScore":2.0,"organism":{"scientificName":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","commonName":"Baker's yeast","taxonId":559292,"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Saccharomycotina","Saccharomycetes","Saccharomycetales","Saccharomycetaceae","Saccharomyces"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized protein YJL107C"}}},"genes":[{"orderedLocusNames":[{"value":"YJL107C"}],"orfNames":[{"value":"J0813"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14562106"}],"value":"Present with 1480 molecules/cell in log phase SD medium"}],"commentType":"MISCELLANEOUS"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the ThrE exporter (TC 2.A.79) family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"This is a truncated version of a ThrE family protein. Strain S288c has a frameshift in position 382, which disrupts the gene coding for this protein and produces two ORFs YJL107C and YJL108C. A contiguous sequence for a S.cerevisiae ThrE family protein can be found in strain YJM789 (AC A6ZQL9)"}],"commentType":"CAUTION"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":387,"modifier":"EXACT"}},"description":"Uncharacterized protein YJL107C","featureId":"PRO_0000203046"},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":126,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":138,"modifier":"EXACT"},"end":{"value":169,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":275,"modifier":"EXACT"},"end":{"value":298,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":32,"modifier":"EXACT"},"end":{"value":45,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":49,"modifier":"EXACT"},"end":{"value":63,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":78,"modifier":"EXACT"},"end":{"value":93,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":155,"modifier":"EXACT"},"end":{"value":169,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":275,"modifier":"EXACT"},"end":{"value":296,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]}],"keywords":[{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"7483851","citationType":"journal article","authors":["Rasmussen S.W."],"citationCrossReferences":[{"database":"PubMed","id":"7483851"},{"database":"DOI","id":"10.1002/yea.320110909"}],"title":"A 37.5 kb region of yeast chromosome X includes the SME1, MEF2, GSH1 and CSD3 genes, a TCP-1-related gene, an open reading frame similar to the DAL80 gene, and a tRNA(Arg).","publicationDate":"1995","journal":"Yeast","firstPage":"873","lastPage":"883","volume":"11"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 96604 / S288c / FY1679","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"8641269","citationType":"journal article","authors":["Galibert F.","Alexandraki D.","Baur A.","Boles E.","Chalwatzis N.","Chuat J.-C.","Coster F.","Cziepluch C.","de Haan M.","Domdey H.","Durand P.","Entian K.-D.","Gatius M.","Goffeau A.","Grivell L.A.","Hennemann A.","Herbert C.J.","Heumann K.","Hilger F.","Hollenberg C.P.","Huang M.-E.","Jacq C.","Jauniaux J.-C.","Katsoulou C.","Kirchrath L.","Kleine K.","Kordes E.","Koetter P.","Liebl S.","Louis E.J.","Manus V.","Mewes H.-W.","Miosga T.","Obermaier B.","Perea J.","Pohl T.M.","Portetelle D.","Pujol A.","Purnelle B.","Ramezani Rad M.","Rasmussen S.W.","Rose M.","Rossau R.","Schaaff-Gerstenschlaeger I.","Smits P.H.M.","Scarcez T.","Soriano N.","To Van D.","Tzermia M.","Van Broekhoven A.","Vandenbol M.","Wedler H.","von Wettstein D.","Wambutt R.","Zagulski M.","Zollner A.","Karpfinger-Hartl L."],"citationCrossReferences":[{"database":"PubMed","id":"8641269"},{"database":"DOI","id":"10.1002/j.1460-2075.1996.tb00557.x"}],"title":"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.","publicationDate":"1996","journal":"EMBO J.","firstPage":"2031","lastPage":"2049","volume":"15"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"24374639","citationType":"journal article","authors":["Engel S.R.","Dietrich F.S.","Fisk D.G.","Binkley G.","Balakrishnan R.","Costanzo M.C.","Dwight S.S.","Hitz B.C.","Karra K.","Nash R.S.","Weng S.","Wong E.D.","Lloyd P.","Skrzypek M.S.","Miyasato S.R.","Simison M.","Cherry J.M."],"citationCrossReferences":[{"database":"PubMed","id":"24374639"},{"database":"DOI","id":"10.1534/g3.113.008995"}],"title":"The reference genome sequence of Saccharomyces cerevisiae: Then and now.","publicationDate":"2014","journal":"G3 (Bethesda)","firstPage":"389","lastPage":"398","volume":"4"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"17322287","citationType":"journal article","authors":["Hu Y.","Rolfs A.","Bhullar B.","Murthy T.V.S.","Zhu C.","Berger M.F.","Camargo A.A.","Kelley F.","McCarron S.","Jepson D.","Richardson A.","Raphael J.","Moreira D.","Taycher E.","Zuo D.","Mohr S.","Kane M.F.","Williamson J.","Simpson A.J.G.","Bulyk M.L.","Harlow E.","Marsischky G.","Kolodner R.D.","LaBaer J."],"citationCrossReferences":[{"database":"PubMed","id":"17322287"},{"database":"DOI","id":"10.1101/gr.6037607"}],"title":"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.","publicationDate":"2007","journal":"Genome Res.","firstPage":"536","lastPage":"543","volume":"17"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"12844361","citationType":"journal article","authors":["Brachat S.","Dietrich F.S.","Voegeli S.","Zhang Z.","Stuart L.","Lerch A.","Gates K.","Gaffney T.D.","Philippsen P."],"citationCrossReferences":[{"database":"PubMed","id":"12844361"},{"database":"DOI","id":"10.1186/gb-2003-4-7-r45"}],"title":"Reinvestigation of the Saccharomyces cerevisiae genome annotation by comparison to the genome of a related fungus: Ashbya gossypii.","publicationDate":"2003","journal":"Genome Biol.","firstPage":"R45.1","lastPage":"R45.13","volume":"4"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 360-387","CONFIRMATION OF FRAMESHIFT"],"referenceComments":[{"value":"ATCC 204511 / S288c / AB972","type":"STRAIN"}]},{"referenceNumber":6,"citation":{"id":"11054818","citationType":"journal article","authors":["Sychrova H.","Braun V.","Potier S.","Souciet J.L."],"citationCrossReferences":[{"database":"PubMed","id":"11054818"},{"database":"DOI","id":"10.1002/1097-0061(200011)16:15<1377::aid-yea637>3.0.co;2-0"}],"title":"Organization of specific genomic regions of Zygosaccharomyces rouxii and Pichia sorbitophila: comparison with Saccharomyces cerevisiae.","publicationDate":"2000","journal":"Yeast","firstPage":"1377","lastPage":"1385","volume":"16"},"referencePositions":["CONFIRMATION OF FRAMESHIFT"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"},{"value":"ATCC 28383 / FL100 / VTT C-80102","type":"STRAIN"}]},{"referenceNumber":7,"citation":{"id":"14562106","citationType":"journal article","authors":["Ghaemmaghami S.","Huh W.-K.","Bower K.","Howson R.W.","Belle A.","Dephoure N.","O'Shea E.K.","Weissman J.S."],"citationCrossReferences":[{"database":"PubMed","id":"14562106"},{"database":"DOI","id":"10.1038/nature02046"}],"title":"Global analysis of protein expression in yeast.","publicationDate":"2003","journal":"Nature","firstPage":"737","lastPage":"741","volume":"425"},"referencePositions":["LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"X85021","properties":[{"key":"ProteinId","value":"CAA59387.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"Z49383","properties":[{"key":"ProteinId","value":"CAA89403.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY557885","properties":[{"key":"ProteinId","value":"AAS56211.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY227895","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BK006943","properties":[{"key":"ProteinId","value":"DAA08693.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"S53380","properties":[{"key":"EntryName","value":"S53380"}]},{"database":"RefSeq","id":"NP_012428.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001181540.1"}]},{"database":"AlphaFoldDB","id":"P42947","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"33649","properties":[{"key":"Interactions","value":"148"}]},{"database":"DIP","id":"DIP-5095N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P42947","properties":[{"key":"Number of interactors","value":"63"}]},{"database":"IntAct","id":"P42947","properties":[{"key":"Interactions","value":"1"}]},{"database":"MINT","id":"P42947","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"4932.YJL107C","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"P42947","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"4932-YJL107C","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"P42947","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblFungi","id":"YJL107C_mRNA","properties":[{"key":"ProteinId","value":"YJL107C"},{"key":"GeneId","value":"YJL107C"}]},{"database":"GeneID","id":"853337","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"sce:YJL107C","properties":[{"key":"Description","value":"-"}]},{"database":"AGR","id":"SGD:S000003643","properties":[{"key":"Description","value":"-"}]},{"database":"SGD","id":"S000003643","properties":[{"key":"GeneName","value":"YJL107C"}]},{"database":"VEuPathDB","id":"FungiDB:YJL107C","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG502QPMM","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_060178_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P42947","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"DGQFCIF","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"413008at2759","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"YEAST:G3O-31561-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID-ORCS","id":"853337","properties":[{"key":"hits","value":"0 hits in 10 CRISPR screens"}]},{"database":"PRO","id":"PR:P42947","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000002311","properties":[{"key":"Component","value":"Chromosome X"}]},{"database":"RNAct","id":"P42947","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"GO","id":"GO:0022857","properties":[{"key":"GoTerm","value":"F:transmembrane transporter activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"InterPro","id":"IPR010619","properties":[{"key":"EntryName","value":"ThrE-like_N"}]},{"database":"InterPro","id":"IPR051361","properties":[{"key":"EntryName","value":"ThrE/Ser_Exporter"}]},{"database":"PANTHER","id":"PTHR31082","properties":[{"key":"EntryName","value":"PHEROMONE-REGULATED MEMBRANE PROTEIN 10"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR31082:SF4","properties":[{"key":"EntryName","value":"PHEROMONE-REGULATED MEMBRANE PROTEIN 10"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF06738","properties":[{"key":"EntryName","value":"ThrE"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MDGRNEKPTTPVSDFRVGSSEQSQAGVNLEDSSDHRTSNSAESKKGNLSGKSISDLGISNNDNKNVRFTADTDALENDLSSRSTETSDNSKGTDGQDEEDRPARHKRKPKVSFTHLRNNGKDGDDETFIKKIINNLTGNQGGLVPGLAPIPSENENGKNDIEKNNRNEEIPLSDLADASKIVDVHEGDDKEKLEALKLEGDVNCTSDGETLGSSSKNSFLAPAVDHFDDYAENNSSDDNEGFIETSTYVPPPSQVKSGVLGSLLKLYQNEDQNSSSIFSDSQAVTTDDEGISSTAGNKDVPVAKRSRLQNLKGKAKKGRMPRLKKRLKTEAKITVHIADILQRHRFILRMCRALMMYGAPTHRLEEYMVMTSRVLEIDGQFCIFQVV","length":387,"molWeight":42508,"crc64":"D7659D1955F5677F","md5":"F4789C802E993FECE82787C2D0CB44B9"},"extraAttributes":{"countByCommentType":{"MISCELLANEOUS":1,"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Chain":1,"Region":3,"Compositional bias":5},"uniParcId":"UPI000013B5E2"}}