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May be expressed during the precursor stage of myogenic differentiation"}],"commentType":"DEVELOPMENTAL STAGE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"22492353"}],"value":"Up-regulated by VEGFA"}],"commentType":"INDUCTION"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":380,"modifier":"EXACT"}},"description":"Transcription factor SOX-7","featureId":"PRO_0000048732"},{"type":"Domain","location":{"start":{"value":260,"modifier":"EXACT"},"end":{"value":380,"modifier":"EXACT"}},"description":"Sox C-terminal","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00849"}]},{"type":"DNA binding","location":{"start":{"value":45,"modifier":"EXACT"},"end":{"value":113,"modifier":"EXACT"}},"description":"HMG box","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00267"}]},{"type":"Region","location":{"start":{"value":24,"modifier":"EXACT"},"end":{"value":43,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":139,"modifier":"EXACT"},"end":{"value":167,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":323,"modifier":"EXACT"},"end":{"value":328,"modifier":"EXACT"}},"description":"Required for beta-catenin-binding"},{"type":"Mutagenesis","location":{"start":{"value":323,"modifier":"EXACT"},"end":{"value":328,"modifier":"EXACT"}},"description":"Loss of beta-catenin-binding.","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11691915"}],"alternativeSequence":{}}],"keywords":[{"id":"KW-0010","category":"Molecular function","name":"Activator"},{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"id":"KW-0539","category":"Cellular component","name":"Nucleus"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"10320775","citationType":"journal article","authors":["Taniguchi K.","Hiraoka Y.","Ogawa M.","Sakai Y.","Kido S.","Aiso S."],"citationCrossReferences":[{"database":"PubMed","id":"10320775"},{"database":"DOI","id":"10.1016/s0167-4781(99)00047-0"}],"title":"Isolation and characterization of a mouse SRY-related cDNA, mSox7.","publicationDate":"1999","journal":"Biochim. 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