{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P36888","comments":[{"commentType":"SUBCELLULAR LOCATION","note":{"texts":[{"value":"Constitutively activated mutant forms with internal tandem duplications are less efficiently transported to the cell surface and a significant proportion is retained in an immature form in the endoplasmic reticulum lumen. The activated kinase is rapidly targeted for degradation"}]},"subcellularLocations":[{"location":{"value":"Membrane","id":"SL-0162"},"topology":{"value":"Single-pass type I membrane protein","id":"SL-9905"}},{"location":{"value":"Endoplasmic reticulum lumen","id":"SL-0096"}}]}],"extraAttributes":{"uniParcId":"UPI00001FC90B"}}