{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P34558","uniProtkbId":"YNP5_CAEEL","entryAudit":{"firstPublicDate":"1994-02-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2001-07-11","entryVersion":149,"sequenceVersion":2},"annotationScore":2.0,"organism":{"scientificName":"Caenorhabditis elegans","taxonId":6239,"lineage":["Eukaryota","Metazoa","Ecdysozoa","Nematoda","Chromadorea","Rhabditida","Rhabditina","Rhabditomorpha","Rhabditoidea","Rhabditidae","Peloderinae","Caenorhabditis"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized protein T05G5.5"}}},"genes":[{"orfNames":[{"value":"T05G5.5"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the CoaE family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":237,"modifier":"EXACT"}},"description":"Uncharacterized protein T05G5.5","featureId":"PRO_0000173044"},{"type":"Domain","location":{"start":{"value":13,"modifier":"EXACT"},"end":{"value":218,"modifier":"EXACT"}},"description":"DPCK"},{"type":"Binding site","location":{"start":{"value":18,"modifier":"EXACT"},"end":{"value":25,"modifier":"EXACT"}},"description":"","featureCrossReferences":[{"database":"ChEBI","id":"CHEBI:30616"}],"evidences":[{"evidenceCode":"ECO:0000255"}],"ligand":{"name":"ATP","id":"ChEBI:CHEBI:30616"}}],"keywords":[{"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"7906398","citationType":"journal article","authors":["Wilson R.","Ainscough R.","Anderson K.","Baynes C.","Berks M.","Bonfield J.","Burton J.","Connell M.","Copsey T.","Cooper J.","Coulson A.","Craxton M.","Dear S.","Du Z.","Durbin R.","Favello A.","Fraser A.","Fulton L.","Gardner A.","Green P.","Hawkins T.","Hillier L.","Jier M.","Johnston L.","Jones M.","Kershaw J.","Kirsten J.","Laisster N.","Latreille P.","Lightning J.","Lloyd C.","Mortimore B.","O'Callaghan M.","Parsons J.","Percy C.","Rifken L.","Roopra A.","Saunders D.","Shownkeen R.","Sims M.","Smaldon N.","Smith A.","Smith M.","Sonnhammer E.","Staden R.","Sulston J.","Thierry-Mieg J.","Thomas K.","Vaudin M.","Vaughan K.","Waterston R.","Watson A.","Weinstock L.","Wilkinson-Sproat J.","Wohldman P."],"citationCrossReferences":[{"database":"PubMed","id":"7906398"},{"database":"DOI","id":"10.1038/368032a0"}],"title":"2.2 Mb of contiguous nucleotide sequence from chromosome III of C. elegans.","publicationDate":"1994","journal":"Nature","firstPage":"32","lastPage":"38","volume":"368"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"Bristol N2","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9851916","citationType":"journal article","authoringGroup":["The C. elegans sequencing consortium"],"citationCrossReferences":[{"database":"PubMed","id":"9851916"},{"database":"DOI","id":"10.1126/science.282.5396.2012"}],"title":"Genome sequence of the nematode C. elegans: a platform for investigating biology.","publicationDate":"1998","journal":"Science","firstPage":"2012","lastPage":"2018","volume":"282"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"Bristol N2","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"Z27079","properties":[{"key":"ProteinId","value":"CAA81598.2"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"B88564","properties":[{"key":"EntryName","value":"B88564"}]},{"database":"RefSeq","id":"NP_001255023.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001268094.4"}]},{"database":"AlphaFoldDB","id":"P34558","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P34558","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P34558","properties":[{"key":"Number of interactors","value":"2074"}]},{"database":"STRING","id":"6239.T05G5.5d.1","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"6239-T05G5.5d.1","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblMetazoa","id":"T05G5.5a.1","properties":[{"key":"ProteinId","value":"T05G5.5a.1"},{"key":"GeneId","value":"WBGene00011500"}]},{"database":"GeneID","id":"176375","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"cel:CELE_T05G5.5","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"T05G5.5","properties":[{"key":"OrganismName","value":"c. elegans"}]},{"database":"AGR","id":"WB:WBGene00011500","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"176375","properties":[{"key":"Description","value":"-"}]},{"database":"WormBase","id":"T05G5.5a","properties":[{"key":"ProteinId","value":"CE23950"},{"key":"GeneId","value":"WBGene00011500"},{"key":"GeneName","value":"-"}]},{"database":"eggNOG","id":"KOG3220","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"InParanoid","id":"P34558","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"247245at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P34558","properties":[{"key":"Description","value":"-"}]},{"database":"Reactome","id":"R-CEL-196783","properties":[{"key":"PathwayName","value":"Coenzyme A biosynthesis"}]},{"database":"PRO","id":"PR:P34558","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001940","properties":[{"key":"Component","value":"Chromosome III"}]},{"database":"Bgee","id":"WBGene00011500","properties":[{"key":"ExpressionPatterns","value":"Expressed in embryo and 4 other cell types or tissues"}]},{"database":"ExpressionAtlas","id":"P34558","properties":[{"key":"ExpressionPatterns","value":"baseline and differential"}]},{"database":"GO","id":"GO:0005739","properties":[{"key":"GoTerm","value":"C:mitochondrion"},{"key":"GoEvidenceType","value":"HDA:WormBase"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"21611156"}]},{"database":"GO","id":"GO:0005524","properties":[{"key":"GoTerm","value":"F:ATP binding"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0004140","properties":[{"key":"GoTerm","value":"F:dephospho-CoA kinase activity"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0015937","properties":[{"key":"GoTerm","value":"P:coenzyme A biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd02022","properties":[{"key":"EntryName","value":"DPCK"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.40.50.300:FF:002606","properties":[{"key":"EntryName","value":"Dephospho-CoA kinase 2"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.300","properties":[{"key":"EntryName","value":"P-loop containing nucleotide triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"HAMAP","id":"MF_00376","properties":[{"key":"EntryName","value":"Dephospho_CoA_kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR001977","properties":[{"key":"EntryName","value":"Depp_CoAkinase"}]},{"database":"InterPro","id":"IPR027417","properties":[{"key":"EntryName","value":"P-loop_NTPase"}]},{"database":"NCBIfam","id":"TIGR00152","properties":[{"key":"EntryName","value":"dephospho-CoA kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10695:SF46","properties":[{"key":"EntryName","value":"BIFUNCTIONAL COENZYME A SYNTHASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR10695","properties":[{"key":"EntryName","value":"DEPHOSPHO-COA KINASE-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01121","properties":[{"key":"EntryName","value":"CoaE"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF52540","properties":[{"key":"EntryName","value":"P-loop containing nucleoside triphosphate hydrolases"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51219","properties":[{"key":"EntryName","value":"DPCK"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MWLDWFFPIEMLVVGLSGGVATGKSTVSSVFRAHGVPIIDADQVARQVVVPGTSTYNRLRKEFGDEYFDDEHGGVLRRDKLGKLIFSNPEKRKALNGITHPAIRWEMFKQFLTLLITGTKYIVFDTPLLFESGYDKWIGTTIVVWCDFEQEVERMVTRDNISRADAESRIHAQMDIEEKKKRAKIVIDNNGNIDELREKVKHVIAQLDKSWKPYIFRVAFGIILGVVPYYFFKYIRS","length":237,"molWeight":27384,"crc64":"011E3AA5BBBDDFC7","md5":"C1E108223CC67C0AEAC7AA0405C2AACB"},"extraAttributes":{"countByCommentType":{"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Domain":1,"Binding site":1},"uniParcId":"UPI0000061156"}}