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Promotes DNA relaxation of bacterial host genome. Modulates the expression of various host genes probably controlled by supercoiling of their promoters. Host genes affected include DNA replication and cell division determinants (By similarity)"}],"commentType":"FUNCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Homodimer"}],"commentType":"SUBUNIT"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Host cytoplasm","id":"SL-0381"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"This protein is constitively expressed from the Pgem promoter unlike most other early proteins which are expressed under the control of the Pe promoter. Its expression seems to escape repression by repressor protein c and thus occurs throughout latency (Probable)"}],"commentType":"INDUCTION"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the mulikevirus gemA protein family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":183,"modifier":"EXACT"}},"description":"GemA protein","featureId":"PRO_0000077788"}],"keywords":[{"id":"KW-0244","category":"Developmental stage","name":"Early protein"},{"id":"KW-1035","category":"Cellular component","name":"Host cytoplasm"},{"id":"KW-0945","category":"Biological process","name":"Host-virus interaction"},{"id":"KW-1121","category":"Biological process","name":"Modulation of host cell cycle by virus"}],"references":[{"referenceNumber":1,"citation":{"id":"CI-4LKHE4GU18LNU","citationType":"submission","authors":["Kropinski A.M.","Villegas A.","Lingohr E.J."],"publicationDate":"JUL-2009","submissionDatabase":"EMBL/GenBank/DDBJ databases"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"]},{"referenceNumber":2,"citation":{"id":"2147059","citationType":"journal article","authors":["Pato M.L.","Banerjee M.","Wagonner B.T."],"citationCrossReferences":[{"database":"PubMed","id":"2147059"},{"database":"DOI","id":"10.1093/nar/18.21.6458"}],"title":"Sequence of gene E15 of bacteriophage D108 and comparison with phage Mu.","publicationDate":"1990","journal":"Nucleic Acids Res.","firstPage":"6458","lastPage":"6458","volume":"18"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-26"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"X54298","properties":[{"key":"ProteinId","value":"CAA38198.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"GQ357916","properties":[{"key":"ProteinId","value":"ACV50274.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"S12146","properties":[{"key":"EntryName","value":"S12146"}]},{"database":"RefSeq","id":"YP_003335763.1","properties":[{"key":"NucleotideSequenceId","value":"NC_013594.1"}]},{"database":"SMR","id":"P24796","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"8658826","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"vg:8658826","properties":[{"key":"Description","value":"-"}]},{"database":"OrthoDB","id":"9495at10239","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0030430","properties":[{"key":"GoTerm","value":"C:host cell cytoplasm"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0044071","properties":[{"key":"GoTerm","value":"P:symbiont-mediated perturbation of host cell cycle progression"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-KW"}]},{"database":"InterPro","id":"IPR009363","properties":[{"key":"EntryName","value":"Phage_Mu_Gp16"}]},{"database":"Pfam","id":"PF06252","properties":[{"key":"EntryName","value":"GemA"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MSRTSLIKLIHVARRELQLDDDTYRAFLMQKTGKISCRELTVTQLEQVLDAMKERGFKKLNKYPRRRFKEHVTPREKVYKIWQQMAEDGFITDGGDVALDKYVQRLTAKRNGGQGVSTLAWCHGESLQVVLETLKQWHIRCIREAFSRHGLPLPVSPSGRELRGYDAMTAAYAHARKTRRMAQ","length":183,"molWeight":21218,"crc64":"6F971FE19BA7FAC8","md5":"45E0A21B3ED43B29F920544D529FCD92"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBUNIT":1,"SUBCELLULAR LOCATION":1,"INDUCTION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1},"uniParcId":"UPI0001B607E7"}}