{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P21373","secondaryAccessions":["D6VWM0","E9P8Y8","Q54AD8"],"uniProtkbId":"UTR1_YEAST","entryAudit":{"firstPublicDate":"1991-05-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1995-02-01","entryVersion":193,"sequenceVersion":2},"annotationScore":5.0,"organism":{"scientificName":"Saccharomyces cerevisiae (strain ATCC 204508 / S288c)","commonName":"Baker's yeast","taxonId":559292,"lineage":["Eukaryota","Fungi","Dikarya","Ascomycota","Saccharomycotina","Saccharomycetes","Saccharomycetales","Saccharomycetaceae","Saccharomyces"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"NAD(+) kinase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11425472"}],"value":"2.7.1.23"}]},"alternativeNames":[{"fullName":{"value":"Unknown transcript 1 protein"}}]},"genes":[{"geneName":{"value":"UTR1"},"orderedLocusNames":[{"value":"YJR049C"}],"orfNames":[{"value":"J1655"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11425472"}],"value":"Specifically phosphorylates NAD in the presence of ATP, dATP, or CTP as phosphoryl donors"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"NAD(+) + ATP = ADP + NADP(+) + H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:18629"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:57540"},{"database":"ChEBI","id":"CHEBI:58349"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"2.7.1.23","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11425472"}]},"physiologicalReactions":[{"directionType":"left-to-right","reactionCrossReference":{"database":"Rhea","id":"RHEA:18630"},"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11425472"}]}]},{"commentType":"BIOPHYSICOCHEMICAL PROPERTIES","kineticParameters":{"michaelisConstants":[{"constant":0.5,"unit":"mM","substrate":"NAD","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11425472"}]},{"constant":0.6,"unit":"mM","substrate":"ATP","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11425472"}]}]},"phDependence":{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11425472"}],"value":"Optimum pH is 8.0."}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"11425472"}],"value":"Homohexamer"}],"commentType":"SUBUNIT"},{"commentType":"INTERACTION","interactions":[{"interactantOne":{"uniProtKBAccession":"P21373","intActId":"EBI-20174"},"interactantTwo":{"uniProtKBAccession":"P32622","geneName":"YEF1","intActId":"EBI-22350"},"numberOfExperiments":5,"organismDiffer":false}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"14562106"}],"value":"Present with 5040 molecules/cell in log phase SD medium"}],"commentType":"MISCELLANEOUS"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the NAD kinase family"}],"commentType":"SIMILARITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Was briefly thought to be FRE2"}],"commentType":"CAUTION"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":530,"modifier":"EXACT"}},"description":"NAD(+) kinase","featureId":"PRO_0000120716"},{"type":"Region","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":27,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":57,"modifier":"EXACT"},"end":{"value":99,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Region","location":{"start":{"value":486,"modifier":"EXACT"},"end":{"value":530,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":13,"modifier":"EXACT"},"end":{"value":25,"modifier":"EXACT"}},"description":"Basic and acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":59,"modifier":"EXACT"},"end":{"value":75,"modifier":"EXACT"}},"description":"Low complexity","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":88,"modifier":"EXACT"},"end":{"value":99,"modifier":"EXACT"}},"description":"Polar residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Compositional bias","location":{"start":{"value":499,"modifier":"EXACT"},"end":{"value":508,"modifier":"EXACT"}},"description":"Acidic residues","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Modified residue","location":{"start":{"value":499,"modifier":"EXACT"},"end":{"value":499,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"18407956"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"19779198"}]},{"type":"Modified residue","location":{"start":{"value":503,"modifier":"EXACT"},"end":{"value":503,"modifier":"EXACT"}},"description":"Phosphoserine","evidences":[{"evidenceCode":"ECO:0007744","source":"PubMed","id":"18407956"},{"evidenceCode":"ECO:0007744","source":"PubMed","id":"19779198"}]},{"type":"Sequence conflict","location":{"start":{"value":337,"modifier":"EXACT"},"end":{"value":337,"modifier":"EXACT"}},"description":"in Ref. 6; AAT92918","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"A","alternativeSequences":["V"]}}],"keywords":[{"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"id":"KW-0418","category":"Molecular function","name":"Kinase"},{"id":"KW-0520","category":"Ligand","name":"NAD"},{"id":"KW-0521","category":"Ligand","name":"NADP"},{"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"id":"KW-0597","category":"PTM","name":"Phosphoprotein"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0808","category":"Molecular function","name":"Transferase"}],"references":[{"referenceNumber":1,"citation":{"id":"11425472","citationType":"journal article","authors":["Kawai S.","Mori S.","Suzuki S.","Murata K."],"citationCrossReferences":[{"database":"PubMed","id":"11425472"},{"database":"DOI","id":"10.1111/j.1574-6968.2001.tb10712.x"}],"title":"Molecular cloning and identification of UTR1 of a yeast Saccharomyces cerevisiae as a gene encoding an NAD kinase.","publicationDate":"2001","journal":"FEMS Microbiol. Lett.","firstPage":"181","lastPage":"184","volume":"200"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]","FUNCTION","CATALYTIC ACTIVITY","BIOPHYSICOCHEMICAL PROPERTIES","SUBUNIT"]},{"referenceNumber":2,"citation":{"id":"2158927","citationType":"journal article","authors":["Melnick L.","Sherman F."],"citationCrossReferences":[{"database":"PubMed","id":"2158927"},{"database":"DOI","id":"10.1016/0378-1119(90)90297-5"}],"title":"Nucleotide sequence of the COR region: a cluster of six genes in the yeast Saccharomyces cerevisiae.","publicationDate":"1990","journal":"Gene","firstPage":"157","lastPage":"166","volume":"87"},"referencePositions":["PRELIMINARY NUCLEOTIDE SEQUENCE"]},{"referenceNumber":3,"citation":{"id":"7975898","citationType":"journal article","authors":["Huang M.-E.","Manus V.","Chuat J.-C.","Galibert F."],"citationCrossReferences":[{"database":"PubMed","id":"7975898"},{"database":"DOI","id":"10.1002/yea.320100611"}],"title":"Revised nucleotide sequence of the COR region of yeast Saccharomyces cerevisiae chromosome X.","publicationDate":"1994","journal":"Yeast","firstPage":"811","lastPage":"818","volume":"10"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"8641269","citationType":"journal article","authors":["Galibert F.","Alexandraki D.","Baur A.","Boles E.","Chalwatzis N.","Chuat J.-C.","Coster F.","Cziepluch C.","de Haan M.","Domdey H.","Durand P.","Entian K.-D.","Gatius M.","Goffeau A.","Grivell L.A.","Hennemann A.","Herbert C.J.","Heumann K.","Hilger F.","Hollenberg C.P.","Huang M.-E.","Jacq C.","Jauniaux J.-C.","Katsoulou C.","Kirchrath L.","Kleine K.","Kordes E.","Koetter P.","Liebl S.","Louis E.J.","Manus V.","Mewes H.-W.","Miosga T.","Obermaier B.","Perea J.","Pohl T.M.","Portetelle D.","Pujol A.","Purnelle B.","Ramezani Rad M.","Rasmussen S.W.","Rose M.","Rossau R.","Schaaff-Gerstenschlaeger I.","Smits P.H.M.","Scarcez T.","Soriano N.","To Van D.","Tzermia M.","Van Broekhoven A.","Vandenbol M.","Wedler H.","von Wettstein D.","Wambutt R.","Zagulski M.","Zollner A.","Karpfinger-Hartl L."],"citationCrossReferences":[{"database":"PubMed","id":"8641269"},{"database":"DOI","id":"10.1002/j.1460-2075.1996.tb00557.x"}],"title":"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.","publicationDate":"1996","journal":"EMBO J.","firstPage":"2031","lastPage":"2049","volume":"15"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"24374639","citationType":"journal article","authors":["Engel S.R.","Dietrich F.S.","Fisk D.G.","Binkley G.","Balakrishnan R.","Costanzo M.C.","Dwight S.S.","Hitz B.C.","Karra K.","Nash R.S.","Weng S.","Wong E.D.","Lloyd P.","Skrzypek M.S.","Miyasato S.R.","Simison M.","Cherry J.M."],"citationCrossReferences":[{"database":"PubMed","id":"24374639"},{"database":"DOI","id":"10.1534/g3.113.008995"}],"title":"The reference genome sequence of Saccharomyces cerevisiae: Then and now.","publicationDate":"2014","journal":"G3 (Bethesda)","firstPage":"389","lastPage":"398","volume":"4"},"referencePositions":["GENOME REANNOTATION"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":6,"citation":{"id":"17322287","citationType":"journal article","authors":["Hu Y.","Rolfs A.","Bhullar B.","Murthy T.V.S.","Zhu C.","Berger M.F.","Camargo A.A.","Kelley F.","McCarron S.","Jepson D.","Richardson A.","Raphael J.","Moreira D.","Taycher E.","Zuo D.","Mohr S.","Kane M.F.","Williamson J.","Simpson A.J.G.","Bulyk M.L.","Harlow E.","Marsischky G.","Kolodner R.D.","LaBaer J."],"citationCrossReferences":[{"database":"PubMed","id":"17322287"},{"database":"DOI","id":"10.1101/gr.6037607"}],"title":"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.","publicationDate":"2007","journal":"Genome Res.","firstPage":"536","lastPage":"543","volume":"17"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 204508 / S288c","type":"STRAIN"}]},{"referenceNumber":7,"citation":{"id":"14562106","citationType":"journal article","authors":["Ghaemmaghami S.","Huh W.-K.","Bower K.","Howson R.W.","Belle A.","Dephoure N.","O'Shea E.K.","Weissman J.S."],"citationCrossReferences":[{"database":"PubMed","id":"14562106"},{"database":"DOI","id":"10.1038/nature02046"}],"title":"Global analysis of protein expression in yeast.","publicationDate":"2003","journal":"Nature","firstPage":"737","lastPage":"741","volume":"425"},"referencePositions":["LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]"]},{"referenceNumber":8,"citation":{"id":"17287358","citationType":"journal article","authors":["Chi A.","Huttenhower C.","Geer L.Y.","Coon J.J.","Syka J.E.P.","Bai D.L.","Shabanowitz J.","Burke D.J.","Troyanskaya O.G.","Hunt D.F."],"citationCrossReferences":[{"database":"PubMed","id":"17287358"},{"database":"DOI","id":"10.1073/pnas.0607084104"}],"title":"Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.","publicationDate":"2007","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"2193","lastPage":"2198","volume":"104"},"referencePositions":["IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":9,"citation":{"id":"18407956","citationType":"journal article","authors":["Albuquerque C.P.","Smolka M.B.","Payne S.H.","Bafna V.","Eng J.","Zhou H."],"citationCrossReferences":[{"database":"PubMed","id":"18407956"},{"database":"DOI","id":"10.1074/mcp.m700468-mcp200"}],"title":"A multidimensional chromatography technology for in-depth phosphoproteome analysis.","publicationDate":"2008","journal":"Mol. Cell. Proteomics","firstPage":"1389","lastPage":"1396","volume":"7"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-499 AND SER-503","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":10,"citation":{"id":"19779198","citationType":"journal article","authors":["Holt L.J.","Tuch B.B.","Villen J.","Johnson A.D.","Gygi S.P.","Morgan D.O."],"citationCrossReferences":[{"database":"PubMed","id":"19779198"},{"database":"DOI","id":"10.1126/science.1172867"}],"title":"Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.","publicationDate":"2009","journal":"Science","firstPage":"1682","lastPage":"1686","volume":"325"},"referencePositions":["PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-499 AND SER-503","IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]},{"referenceNumber":11,"citation":{"id":"22814378","citationType":"journal article","authors":["Van Damme P.","Lasa M.","Polevoda B.","Gazquez C.","Elosegui-Artola A.","Kim D.S.","De Juan-Pardo E.","Demeyer K.","Hole K.","Larrea E.","Timmerman E.","Prieto J.","Arnesen T.","Sherman F.","Gevaert K.","Aldabe R."],"citationCrossReferences":[{"database":"PubMed","id":"22814378"},{"database":"DOI","id":"10.1073/pnas.1210303109"}],"title":"N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.","publicationDate":"2012","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"12449","lastPage":"12454","volume":"109"},"referencePositions":["IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AB044344","properties":[{"key":"ProteinId","value":"BAB83863.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"L26347","properties":[{"key":"ProteinId","value":"AAA62857.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"L36344","properties":[{"key":"ProteinId","value":"AAA88752.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"M37696","properties":[{"key":"ProteinId","value":"-"},{"key":"Status","value":"NOT_ANNOTATED_CDS"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"Z49549","properties":[{"key":"ProteinId","value":"CAA89577.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AY692899","properties":[{"key":"ProteinId","value":"AAT92918.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"BK006943","properties":[{"key":"ProteinId","value":"DAA08836.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"S46589","properties":[{"key":"EntryName","value":"S46589"}]},{"database":"RefSeq","id":"NP_012583.1","properties":[{"key":"NucleotideSequenceId","value":"NM_001181707.1"}]},{"database":"AlphaFoldDB","id":"P21373","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P21373","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"33802","properties":[{"key":"Interactions","value":"102"}]},{"database":"DIP","id":"DIP-4479N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P21373","properties":[{"key":"Number of interactors","value":"650"}]},{"database":"IntAct","id":"P21373","properties":[{"key":"Interactions","value":"11"}]},{"database":"MINT","id":"P21373","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"4932.YJR049C","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"P21373","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"4932-YJR049C","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"P21373","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblFungi","id":"YJR049C_mRNA","properties":[{"key":"ProteinId","value":"YJR049C"},{"key":"GeneId","value":"YJR049C"}]},{"database":"GeneID","id":"853508","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"sce:YJR049C","properties":[{"key":"Description","value":"-"}]},{"database":"AGR","id":"SGD:S000003810","properties":[{"key":"Description","value":"-"}]},{"database":"SGD","id":"S000003810","properties":[{"key":"GeneName","value":"UTR1"}]},{"database":"VEuPathDB","id":"FungiDB:YJR049C","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"KOG2178","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_008831_1_5_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P21373","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"MRMRLCC","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"24581at2759","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"MetaCyc:G3O-31684-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"YEAST:G3O-31684-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"BRENDA","id":"2.7.1.23","properties":[{"key":"OrganismId","value":"984"}]},{"database":"BRENDA","id":"2.7.1.86","properties":[{"key":"OrganismId","value":"984"}]},{"database":"Reactome","id":"R-SCE-196807","properties":[{"key":"PathwayName","value":"Nicotinate metabolism"}]},{"database":"BioGRID-ORCS","id":"853508","properties":[{"key":"hits","value":"2 hits in 10 CRISPR screens"}]},{"database":"PRO","id":"PR:P21373","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000002311","properties":[{"key":"Component","value":"Chromosome X"}]},{"database":"RNAct","id":"P21373","properties":[{"key":"moleculeType","value":"protein"}]},{"database":"GO","id":"GO:0005737","properties":[{"key":"GoTerm","value":"C:cytoplasm"},{"key":"GoEvidenceType","value":"HDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"14562095"}]},{"database":"GO","id":"GO:0005634","properties":[{"key":"GoTerm","value":"C:nucleus"},{"key":"GoEvidenceType","value":"HDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"14562095"}]},{"database":"GO","id":"GO:0003951","properties":[{"key":"GoTerm","value":"F:NAD+ kinase activity"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"11425472"}]},{"database":"GO","id":"GO:0042736","properties":[{"key":"GoTerm","value":"F:NADH kinase activity"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"15978040"}]},{"database":"GO","id":"GO:0006879","properties":[{"key":"GoTerm","value":"P:intracellular iron ion homeostasis"},{"key":"GoEvidenceType","value":"IMP:SGD"}],"evidences":[{"evidenceCode":"ECO:0000315","source":"PubMed","id":"8662826"}]},{"database":"GO","id":"GO:0019674","properties":[{"key":"GoTerm","value":"P:NAD+ metabolic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"GO","id":"GO:0006741","properties":[{"key":"GoTerm","value":"P:NADP+ biosynthetic process"},{"key":"GoEvidenceType","value":"IDA:SGD"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"11425472"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"15978040"}]},{"database":"FunFam","id":"3.40.50.10330:FF:000025","properties":[{"key":"EntryName","value":"NAD+ kinase Utr1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.60.200.30:FF:000009","properties":[{"key":"EntryName","value":"Poly(P)/ATP NAD kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.40.50.10330","properties":[{"key":"EntryName","value":"Probable inorganic polyphosphate/atp-NAD kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.60.200.30","properties":[{"key":"EntryName","value":"Probable inorganic polyphosphate/atp-NAD kinase, domain 2"},{"key":"MatchStatus","value":"1"}]},{"database":"HAMAP","id":"MF_00361","properties":[{"key":"EntryName","value":"NAD_kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR017438","properties":[{"key":"EntryName","value":"ATP-NAD_kinase_N"}]},{"database":"InterPro","id":"IPR017437","properties":[{"key":"EntryName","value":"ATP-NAD_kinase_PpnK-typ_C"}]},{"database":"InterPro","id":"IPR016064","properties":[{"key":"EntryName","value":"NAD/diacylglycerol_kinase_sf"}]},{"database":"InterPro","id":"IPR002504","properties":[{"key":"EntryName","value":"NADK"}]},{"database":"PANTHER","id":"PTHR20275","properties":[{"key":"EntryName","value":"NAD KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR20275:SF0","properties":[{"key":"EntryName","value":"NAD KINASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01513","properties":[{"key":"EntryName","value":"NAD_kinase"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF20143","properties":[{"key":"EntryName","value":"NAD_kinase_C"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF111331","properties":[{"key":"EntryName","value":"NAD kinase/diacylglycerol kinase-like"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKENDMNNGVDKWVNEEDGRNDHHNNNNNLMKKAMMNNEQIDRTQDIDNAKEMLRKISSESSSRRSSLLNKDSSLVNGNANSGGGTSINGTRGSSKSSNTHFQYASTAYGVRMLSKDISNTKVELDVENLMIVTKLNDVSLYFLTRELVEWVLVHFPRVTVYVDSELKNSKKFAAGELCEDSKCRESRIKYWTKDFIREHDVFFDLVVTLGGDGTVLFVSSIFQRHVPPVMSFSLGSLGFLTNFKFEHFREDLPRIMNHKIKTNLRLRLECTIYRRHRPEVDPNTGKKICVVEKLSTHHILNEVTIDRGPSPFLSMLELYGDGSLMTVAQADGLIAATPTGSTAYSLSAGGSLVCPTVNAIALTPICPHALSFRPIILPESINLKVKVSMKSRAPAWAAFDGKDRIELQKGDFITICASPYAFPTVEASPDEFINSISRQLNWNVREQQKSFTHILSQKNQEKYAHEANKVRNQAEPLEVIRDKYSLEADATKENNNGSDDESDDESVNCEACKLKPSSVPKPSQARFSV","length":530,"molWeight":59469,"crc64":"1BF4F01D7213B94B","md5":"B904784B0A727F1AA265108E06B566E2"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"BIOPHYSICOCHEMICAL PROPERTIES":1,"SUBUNIT":1,"INTERACTION":1,"MISCELLANEOUS":1,"SIMILARITY":1,"CAUTION":1},"countByFeatureType":{"Chain":1,"Region":3,"Compositional bias":4,"Modified residue":2,"Sequence conflict":1},"uniParcId":"UPI0000000E9D"}}