{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P18007","uniProtkbId":"Y4048_ENTFA","entryAudit":{"firstPublicDate":"1990-11-01","lastAnnotationUpdateDate":"2026-01-28","lastSequenceUpdateDate":"1990-11-01","entryVersion":87,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Enterococcus faecalis (strain ATCC 700802 / V583)","taxonId":226185,"lineage":["Bacteria","Bacillati","Bacillota","Bacilli","Lactobacillales","Enterococcaceae","Enterococcus"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"value":"Uncharacterized protein EF_A0048"}},"alternativeNames":[{"fullName":{"value":"ORF 1"}}]},"genes":[{"orderedLocusNames":[{"value":"EF_A0048"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":111,"modifier":"EXACT"}},"description":"Uncharacterized protein EF_A0048","featureId":"PRO_0000068502"}],"geneLocations":[{"value":"pTEF1","geneEncodingType":"Plasmid"},{"value":"pAD1","geneEncodingType":"Plasmid"}],"keywords":[{"id":"KW-0614","category":"Technical term","name":"Plasmid"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"2120541","citationType":"journal article","authors":["Galli D.","Lottspeich F.","Wirth R."],"citationCrossReferences":[{"database":"PubMed","id":"2120541"},{"database":"DOI","id":"10.1111/j.1365-2958.1990.tb00662.x"}],"title":"Sequence analysis of Enterococcus faecalis aggregation substance encoded by the sex pheromone plasmid pAD1.","publicationDate":"1990","journal":"Mol. Microbiol.","firstPage":"895","lastPage":"904","volume":"4"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"],"referenceComments":[{"value":"DS16","type":"STRAIN"},{"value":"pAD1","type":"PLASMID"}]},{"referenceNumber":2,"citation":{"id":"12663927","citationType":"journal article","authors":["Paulsen I.T.","Banerjei L.","Myers G.S.A.","Nelson K.E.","Seshadri R.","Read T.D.","Fouts D.E.","Eisen J.A.","Gill S.R.","Heidelberg J.F.","Tettelin H.","Dodson R.J.","Umayam L.A.","Brinkac L.M.","Beanan M.J.","Daugherty S.C.","DeBoy R.T.","Durkin S.A.","Kolonay J.F.","Madupu R.","Nelson W.C.","Vamathevan J.J.","Tran B.","Upton J.","Hansen T.","Shetty J.","Khouri H.M.","Utterback T.R.","Radune D.","Ketchum K.A.","Dougherty B.A.","Fraser C.M."],"citationCrossReferences":[{"database":"PubMed","id":"12663927"},{"database":"DOI","id":"10.1126/science.1080613"}],"title":"Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.","publicationDate":"2003","journal":"Science","firstPage":"2071","lastPage":"2074","volume":"299"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"ATCC 700802 / V583","type":"STRAIN"},{"value":"pTEF1","type":"PLASMID"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"X17214","properties":[{"key":"ProteinId","value":"CAA35082.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AE016833","properties":[{"key":"ProteinId","value":"AAO83044.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"S10222","properties":[{"key":"EntryName","value":"S10222"}]},{"database":"RefSeq","id":"WP_002360910.1","properties":[{"key":"NucleotideSequenceId","value":"NC_004669.1"}]},{"database":"AlphaFoldDB","id":"P18007","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"AAO83044","properties":[{"key":"ProteinId","value":"AAO83044"},{"key":"GeneId","value":"EF_A0048"}]},{"database":"KEGG","id":"efa:EFA0048","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|226185.45.peg.3341","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"HOGENOM","id":"CLU_175410_0_0_9","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:P18007","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001415","properties":[{"key":"Component","value":"Plasmid pTEF1"}]},{"database":"InterPro","id":"IPR035387","properties":[{"key":"EntryName","value":"DUF5406"}]},{"database":"Pfam","id":"PF17400","properties":[{"key":"EntryName","value":"DUF5406"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKNYDPNIRWGLHTIKVSFQRGVYKGFVTFVKSGNCKGLDVLGIDEEDLYDMKFKENPINFRLLGEDDNGDEWFAMTLKNDKKDELLVEDVWEELSEYIVRIEIIDFEEEK","length":111,"molWeight":13160,"crc64":"7E6EB476EBFF169B","md5":"11FDA2FF12292A8C0542C9394E009DEE"},"extraAttributes":{"countByFeatureType":{"Chain":1},"uniParcId":"UPI0000059948"}}