{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P13965","uniProtkbId":"KLEB2_ECOLX","entryAudit":{"firstPublicDate":"1990-01-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1990-01-01","entryVersion":66,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Escherichia coli","taxonId":562,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"4: Predicted","proteinDescription":{"recommendedName":{"fullName":{"value":"Protein KleB"}},"alternativeNames":[{"fullName":{"value":"KcrA2 protein"}}]},"genes":[{"geneName":{"value":"kleB"},"synonyms":[{"value":"kcrA2"}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":71,"modifier":"EXACT"}},"description":"Protein KleB","featureId":"PRO_0000068368"},{"type":"DNA binding","location":{"start":{"value":9,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"H-T-H motif","evidences":[{"evidenceCode":"ECO:0000250"}]}],"geneLocations":[{"value":"IncP-alpha RK2","geneEncodingType":"Plasmid"}],"keywords":[{"id":"KW-0238","category":"Molecular function","name":"DNA-binding"},{"id":"KW-0614","category":"Technical term","name":"Plasmid"},{"id":"KW-0804","category":"Biological process","name":"Transcription"},{"id":"KW-0805","category":"Biological process","name":"Transcription regulation"}],"references":[{"referenceNumber":1,"citation":{"id":"2838814","citationType":"journal article","authors":["Thomas C.M.","Ibbotson J.P.","Wang N.","Smith C.A.","Tipping R.","Loader N.M."],"citationCrossReferences":[{"database":"PubMed","id":"2838814"},{"database":"DOI","id":"10.1093/nar/16.12.5345"}],"title":"Gene regulation on broad host range plasmid RK2: identification of three novel operons whose transcription is repressed by both KorA and KorC.","publicationDate":"1988","journal":"Nucleic Acids Res.","firstPage":"5345","lastPage":"5359","volume":"16"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"]},{"referenceNumber":2,"citation":{"id":"8349548","citationType":"journal article","authors":["Kornacki J.A.","Chang C.-H.","Figurski D.H."],"citationCrossReferences":[{"database":"PubMed","id":"8349548"},{"database":"DOI","id":"10.1128/jb.175.16.5078-5090.1993"}],"title":"kil-kor regulon of promiscuous plasmid RK2: structure, products, and regulation of two operons that constitute the kilE locus.","publicationDate":"1993","journal":"J. Bacteriol.","firstPage":"5078","lastPage":"5090","volume":"175"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"X07248","properties":[{"key":"ProteinId","value":"CAA30234.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"L18919","properties":[{"key":"ProteinId","value":"AAA92766.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_011205838.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_BGLU01000028.1"}]},{"database":"AlphaFoldDB","id":"P13965","properties":[{"key":"Description","value":"-"}]},{"database":"InterPro","id":"IPR024392","properties":[{"key":"EntryName","value":"DUF2688"}]},{"database":"Pfam","id":"PF10892","properties":[{"key":"EntryName","value":"DUF2688"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MPNRKIEIVTTNCRRCGKSISTLSRSLIGADALREELGGICGDCITPEERQRIEQGTLLAALRQCAAAGTS","length":71,"molWeight":7605,"crc64":"BDD9D998ABDAE04C","md5":"36D0BC8F5A5E8C9C161E925D68193C14"},"extraAttributes":{"countByFeatureType":{"Chain":1,"DNA binding":1},"uniParcId":"UPI000012DD89"}}