{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P11447","secondaryAccessions":["Q2M8Q5","Q47060"],"uniProtkbId":"ARLY_ECOLI","entryAudit":{"firstPublicDate":"1989-10-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"1993-10-01","entryVersion":195,"sequenceVersion":3},"annotationScore":2.0,"organism":{"scientificName":"Escherichia coli (strain K12)","taxonId":83333,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00006"}],"value":"Argininosuccinate lyase"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00006"}],"value":"ASAL"}],"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00006"}],"value":"4.3.2.1"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00006"}],"value":"Arginosuccinase"}}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00006"}],"value":"argH"},"orderedLocusNames":[{"value":"b3960"},{"value":"JW3932"}]}],"comments":[{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"2-(N(omega)-L-arginino)succinate = fumarate + L-arginine","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:24020"},{"database":"ChEBI","id":"CHEBI:29806"},{"database":"ChEBI","id":"CHEBI:32682"},{"database":"ChEBI","id":"CHEBI:57472"}],"ecNumber":"4.3.2.1","evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00006"}]}},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00006"}],"value":"Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3"}],"commentType":"PATHWAY"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Cytoplasm","id":"SL-0086"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00006"}],"value":"Belongs to the lyase 1 family. Argininosuccinate lyase subfamily"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":457,"modifier":"EXACT"}},"description":"Argininosuccinate lyase","featureId":"PRO_0000137768"},{"type":"Sequence conflict","location":{"start":{"value":28,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"in Ref. 5; AAB59147","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"R","alternativeSequences":["G"]}},{"type":"Sequence conflict","location":{"start":{"value":40,"modifier":"EXACT"},"end":{"value":40,"modifier":"EXACT"}},"description":"in Ref. 5; AAB59147","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"W","alternativeSequences":["R"]}},{"type":"Helix","location":{"start":{"value":11,"modifier":"EXACT"},"end":{"value":13,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":14,"modifier":"EXACT"},"end":{"value":20,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":23,"modifier":"EXACT"},"end":{"value":26,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":27,"modifier":"EXACT"},"end":{"value":29,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":30,"modifier":"EXACT"},"end":{"value":46,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":52,"modifier":"EXACT"},"end":{"value":71,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":73,"modifier":"EXACT"},"end":{"value":78,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":84,"modifier":"EXACT"},"end":{"value":96,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":97,"modifier":"EXACT"},"end":{"value":102,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Turn","location":{"start":{"value":103,"modifier":"EXACT"},"end":{"value":106,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":109,"modifier":"EXACT"},"end":{"value":144,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Turn","location":{"start":{"value":145,"modifier":"EXACT"},"end":{"value":148,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Beta strand","location":{"start":{"value":150,"modifier":"EXACT"},"end":{"value":155,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Beta strand","location":{"start":{"value":158,"modifier":"EXACT"},"end":{"value":164,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":165,"modifier":"EXACT"},"end":{"value":190,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Turn","location":{"start":{"value":198,"modifier":"EXACT"},"end":{"value":201,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":209,"modifier":"EXACT"},"end":{"value":216,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Beta strand","location":{"start":{"value":219,"modifier":"EXACT"},"end":{"value":221,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":225,"modifier":"EXACT"},"end":{"value":230,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":233,"modifier":"EXACT"},"end":{"value":259,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Turn","location":{"start":{"value":262,"modifier":"EXACT"},"end":{"value":264,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":271,"modifier":"EXACT"},"end":{"value":273,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":287,"modifier":"EXACT"},"end":{"value":294,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":296,"modifier":"EXACT"},"end":{"value":310,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":319,"modifier":"EXACT"},"end":{"value":323,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":324,"modifier":"EXACT"},"end":{"value":346,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":353,"modifier":"EXACT"},"end":{"value":360,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Turn","location":{"start":{"value":363,"modifier":"EXACT"},"end":{"value":366,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":367,"modifier":"EXACT"},"end":{"value":376,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":381,"modifier":"EXACT"},"end":{"value":398,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":402,"modifier":"EXACT"},"end":{"value":404,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":407,"modifier":"EXACT"},"end":{"value":410,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Turn","location":{"start":{"value":411,"modifier":"EXACT"},"end":{"value":413,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":421,"modifier":"EXACT"},"end":{"value":424,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":427,"modifier":"EXACT"},"end":{"value":432,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]},{"type":"Helix","location":{"start":{"value":442,"modifier":"EXACT"},"end":{"value":456,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"1TJ7"}]}],"keywords":[{"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"id":"KW-0028","category":"Biological process","name":"Amino-acid biosynthesis"},{"id":"KW-0055","category":"Biological process","name":"Arginine biosynthesis"},{"id":"KW-0963","category":"Cellular component","name":"Cytoplasm"},{"id":"KW-0456","category":"Molecular function","name":"Lyase"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"8265357","citationType":"journal article","authors":["Blattner F.R.","Burland V.D.","Plunkett G. III","Sofia H.J.","Daniels D.L."],"citationCrossReferences":[{"database":"PubMed","id":"8265357"},{"database":"DOI","id":"10.1093/nar/21.23.5408"}],"title":"Analysis of the Escherichia coli genome. IV. DNA sequence of the region from 89.2 to 92.8 minutes.","publicationDate":"1993","journal":"Nucleic Acids Res.","firstPage":"5408","lastPage":"5417","volume":"21"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / MG1655 / ATCC 47076","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9278503","citationType":"journal article","authors":["Blattner F.R.","Plunkett G. III","Bloch C.A.","Perna N.T.","Burland V.","Riley M.","Collado-Vides J.","Glasner J.D.","Rode C.K.","Mayhew G.F.","Gregor J.","Davis N.W.","Kirkpatrick H.A.","Goeden M.A.","Rose D.J.","Mau B.","Shao Y."],"citationCrossReferences":[{"database":"PubMed","id":"9278503"},{"database":"DOI","id":"10.1126/science.277.5331.1453"}],"title":"The complete genome sequence of Escherichia coli K-12.","publicationDate":"1997","journal":"Science","firstPage":"1453","lastPage":"1462","volume":"277"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / MG1655 / ATCC 47076","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"16738553","citationType":"journal article","authors":["Hayashi K.","Morooka N.","Yamamoto Y.","Fujita K.","Isono K.","Choi S.","Ohtsubo E.","Baba T.","Wanner B.L.","Mori H.","Horiuchi T."],"citationCrossReferences":[{"database":"PubMed","id":"16738553"},{"database":"DOI","id":"10.1038/msb4100049"}],"title":"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.","publicationDate":"2006","journal":"Mol. Syst. Biol.","firstPage":"E1","lastPage":"E5","volume":"2"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / W3110 / ATCC 27325 / DSM 5911","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"2851495","citationType":"journal article","authors":["Parsot C.","Boyen A.","Cohen G.N.","Glansdorff N."],"citationCrossReferences":[{"database":"PubMed","id":"2851495"},{"database":"DOI","id":"10.1016/0378-1119(88)90030-3"}],"title":"Nucleotide sequence of Escherichia coli argB and argC genes: comparison of N-acetylglutamate kinase and N-acetylglutamate-gamma-semialdehyde dehydrogenase with homologous and analogous enzymes.","publicationDate":"1988","journal":"Gene","firstPage":"275","lastPage":"283","volume":"68"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-51"]},{"referenceNumber":5,"citation":{"id":"6292860","citationType":"journal article","authors":["Charlier D.R.M.","Piette J.","Glansdorff N."],"citationCrossReferences":[{"database":"PubMed","id":"6292860"},{"database":"DOI","id":"10.1093/nar/10.19.5935"}],"title":"IS3 can function as a mobile promoter in E. coli.","publicationDate":"1982","journal":"Nucleic Acids Res.","firstPage":"5935","lastPage":"5948","volume":"10"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-44"],"referenceComments":[{"value":"K12","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"U00006","properties":[{"key":"ProteinId","value":"AAC43066.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"U00096","properties":[{"key":"ProteinId","value":"AAC76942.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AP009048","properties":[{"key":"ProteinId","value":"BAE77351.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"M21446","properties":[{"key":"ProteinId","value":"AAA23479.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AH005258","properties":[{"key":"ProteinId","value":"AAB59147.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"C65203","properties":[{"key":"EntryName","value":"C65203"}]},{"database":"RefSeq","id":"NP_418395.1","properties":[{"key":"NucleotideSequenceId","value":"NC_000913.3"}]},{"database":"RefSeq","id":"WP_001230087.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP009789.1"}]},{"database":"PDB","id":"1TJ7","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"2.44 A"},{"key":"Chains","value":"A/B=1-457"}]},{"database":"PDBsum","id":"1TJ7","properties":[{"key":"Description","value":"-"}]},{"database":"AlphaFoldDB","id":"P11447","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P11447","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"4263466","properties":[{"key":"Interactions","value":"10"}]},{"database":"DIP","id":"DIP-9142N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P11447","properties":[{"key":"Number of interactors","value":"737"}]},{"database":"STRING","id":"511145.b3960","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"P11447","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"511145-b3960","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"AAC76942","properties":[{"key":"ProteinId","value":"AAC76942"},{"key":"GeneId","value":"b3960"}]},{"database":"GeneID","id":"948463","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecj:JW3932","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"eco:b3960","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecoc:C3026_21400","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|1411691.4.peg.2745","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"EchoBASE","id":"EB1205","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"COG0165","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"HOGENOM","id":"CLU_027272_2_3_6","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P11447","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"DFAIEFC","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"9769623at2","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P11447","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"EcoCyc:ARGSUCCINLYA-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"MetaCyc:ARGSUCCINLYA-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"UniPathway","id":"UPA00068","properties":[{"key":"RectionId","value":"UER00114"}]},{"database":"EvolutionaryTrace","id":"P11447","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:P11447","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000625","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"AbasyAtlas","id":"P11447","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0004056","properties":[{"key":"GoTerm","value":"F:argininosuccinate lyase activity"},{"key":"GoEvidenceType","value":"IDA:EcoCyc"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"6762207"}]},{"database":"GO","id":"GO:0006526","properties":[{"key":"GoTerm","value":"P:L-arginine biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-UniRule"}]},{"database":"CDD","id":"cd01359","properties":[{"key":"EntryName","value":"Argininosuccinate_lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.275.10:FF:000004","properties":[{"key":"EntryName","value":"Argininosuccinate lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.10.40.30:FF:000001","properties":[{"key":"EntryName","value":"Argininosuccinate lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"1.20.200.10:FF:000006","properties":[{"key":"EntryName","value":"Argininosuccinate lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.40.30","properties":[{"key":"EntryName","value":"Fumarase/aspartase (C-terminal domain)"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.20.200.10","properties":[{"key":"EntryName","value":"Fumarase/aspartase (Central domain)"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.10.275.10","properties":[{"key":"EntryName","value":"Fumarase/aspartase (N-terminal domain)"},{"key":"MatchStatus","value":"1"}]},{"database":"HAMAP","id":"MF_00006","properties":[{"key":"EntryName","value":"Arg_succ_lyase"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR029419","properties":[{"key":"EntryName","value":"Arg_succ_lyase_C"}]},{"database":"InterPro","id":"IPR009049","properties":[{"key":"EntryName","value":"Argininosuccinate_lyase"}]},{"database":"InterPro","id":"IPR024083","properties":[{"key":"EntryName","value":"Fumarase/histidase_N"}]},{"database":"InterPro","id":"IPR020557","properties":[{"key":"EntryName","value":"Fumarate_lyase_CS"}]},{"database":"InterPro","id":"IPR000362","properties":[{"key":"EntryName","value":"Fumarate_lyase_fam"}]},{"database":"InterPro","id":"IPR022761","properties":[{"key":"EntryName","value":"Fumarate_lyase_N"}]},{"database":"InterPro","id":"IPR008948","properties":[{"key":"EntryName","value":"L-Aspartase-like"}]},{"database":"NCBIfam","id":"TIGR00838","properties":[{"key":"EntryName","value":"argH"},{"key":"MatchStatus","value":"1"}]},{"database":"NCBIfam","id":"NF008964","properties":[{"key":"EntryName","value":"PRK12308.1"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43814","properties":[{"key":"EntryName","value":"ARGININOSUCCINATE LYASE"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43814:SF1","properties":[{"key":"EntryName","value":"ARGININOSUCCINATE LYASE"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF14698","properties":[{"key":"EntryName","value":"ASL_C2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00206","properties":[{"key":"EntryName","value":"Lyase_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PRINTS","id":"PR00145","properties":[{"key":"EntryName","value":"ARGSUCLYASE"}]},{"database":"PRINTS","id":"PR00149","properties":[{"key":"EntryName","value":"FUMRATELYASE"}]},{"database":"SUPFAM","id":"SSF48557","properties":[{"key":"EntryName","value":"L-aspartase-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS00163","properties":[{"key":"EntryName","value":"FUMARATE_LYASES"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKALVTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKKLHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKPLEDLPLSELQKFSQVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIAFAQARLG","length":457,"molWeight":50318,"crc64":"0109EF31675B9717","md5":"7442579A7F9797C55678402DBB898539"},"extraAttributes":{"countByCommentType":{"CATALYTIC ACTIVITY":1,"PATHWAY":1,"SUBCELLULAR LOCATION":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Sequence conflict":2,"Helix":27,"Turn":6,"Beta strand":3},"uniParcId":"UPI0000125EF5"}}