{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P0AF41","secondaryAccessions":["P27308"],"uniProtkbId":"YIJD_ECOL6","entryAudit":{"firstPublicDate":"2005-12-20","lastAnnotationUpdateDate":"2026-06-10","lastSequenceUpdateDate":"2005-12-20","entryVersion":82,"sequenceVersion":1},"annotationScore":1.0,"organism":{"scientificName":"Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)","taxonId":199310,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"3: Inferred from homology","proteinDescription":{"recommendedName":{"fullName":{"value":"Inner membrane protein YijD"}}},"genes":[{"geneName":{"value":"yijD"},"orderedLocusNames":[{"value":"c4927"}]}],"comments":[{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Cell inner membrane","id":"SL-0037"},"topology":{"evidences":[{"evidenceCode":"ECO:0000250"}],"value":"Multi-pass membrane protein","id":"SL-9909"}}]}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":119,"modifier":"EXACT"}},"description":"Inner membrane protein YijD","featureId":"PRO_0000169700"},{"type":"Topological domain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":8,"modifier":"EXACT"}},"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":9,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":29,"modifier":"EXACT"},"end":{"value":31,"modifier":"EXACT"}},"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":32,"modifier":"EXACT"},"end":{"value":50,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":51,"modifier":"EXACT"},"end":{"value":61,"modifier":"EXACT"}},"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":62,"modifier":"EXACT"},"end":{"value":84,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":85,"modifier":"EXACT"},"end":{"value":88,"modifier":"EXACT"}},"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Transmembrane","location":{"start":{"value":89,"modifier":"EXACT"},"end":{"value":108,"modifier":"EXACT"}},"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Topological domain","location":{"start":{"value":109,"modifier":"EXACT"},"end":{"value":119,"modifier":"EXACT"}},"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}],"keywords":[{"id":"KW-0997","category":"Cellular component","name":"Cell inner membrane"},{"id":"KW-1003","category":"Cellular component","name":"Cell membrane"},{"id":"KW-0472","category":"Cellular component","name":"Membrane"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0812","category":"Domain","name":"Transmembrane"},{"id":"KW-1133","category":"Domain","name":"Transmembrane helix"}],"references":[{"referenceNumber":1,"citation":{"id":"12471157","citationType":"journal article","authors":["Welch R.A.","Burland V.","Plunkett G. III","Redford P.","Roesch P.","Rasko D.","Buckles E.L.","Liou S.-R.","Boutin A.","Hackett J.","Stroud D.","Mayhew G.F.","Rose D.J.","Zhou S.","Schwartz D.C.","Perna N.T.","Mobley H.L.T.","Donnenberg M.S.","Blattner F.R."],"citationCrossReferences":[{"database":"PubMed","id":"12471157"},{"database":"DOI","id":"10.1073/pnas.252529799"}],"title":"Extensive mosaic structure revealed by the complete genome sequence of uropathogenic Escherichia coli.","publicationDate":"2002","journal":"Proc. Natl. Acad. Sci. U.S.A.","firstPage":"17020","lastPage":"17024","volume":"99"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"CFT073 / ATCC 700928 / UPEC","type":"STRAIN"}]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"AE014075","properties":[{"key":"ProteinId","value":"AAN83355.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"RefSeq","id":"WP_000806411.1","properties":[{"key":"NucleotideSequenceId","value":"NC_004431.1"}]},{"database":"AlphaFoldDB","id":"P0AF41","properties":[{"key":"Description","value":"-"}]},{"database":"STRING","id":"199310.c4927","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"67174997","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecc:c4927","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"ENOG5031GYK","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"HOGENOM","id":"CLU_138008_1_0_6","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"ECOL199310:C4927-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001410","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"GO","id":"GO:0005886","properties":[{"key":"GoTerm","value":"C:plasma membrane"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"InterPro","id":"IPR009867","properties":[{"key":"EntryName","value":"DUF1422"}]},{"database":"NCBIfam","id":"NF008278","properties":[{"key":"EntryName","value":"PRK11056.1"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF07226","properties":[{"key":"EntryName","value":"DUF1422"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLVLTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIMVFWIGAKMRNRKQEVAE","length":119,"molWeight":13024,"crc64":"29177570EAF20F3B","md5":"2F6DB36B7105D20F193C42038F4A3B07"},"extraAttributes":{"countByCommentType":{"SUBCELLULAR LOCATION":1},"countByFeatureType":{"Chain":1,"Topological domain":5,"Transmembrane":4},"uniParcId":"UPI000013B427"}}