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  up:title "The amino acid sequence of the A protein (alpha subunit) of the tryptophan synthetase of Escherichia coli." ;
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  up:title "Nucleotide sequences of trpA of Salmonella typhimurium and Escherichia coli: an evolutionary comparison." ;
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  up:title "The complete nucleotide sequence of the tryptophan operon of Escherichia coli." ;
  up:author "Yanofsky C." ,
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  up:title "Molecular evolution of the Escherichia coli chromosome. IV. Sequence comparisons." ;
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  up:title "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to the 28.0-40.1 min region on the linkage map." ;
  up:author "Aiba H." ,
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    "Fujita K." ,
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    "Kasai H." ,
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  up:author "Hayashi K." ,
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  up:title "Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12." ;
  up:author "Link A.J." ,
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  rdfs:comment "2026" .
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  up:database database:PRO .
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  up:database database:AbasyAtlas .
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  up:database database:CDD ;
  rdfs:comment "Tryptophan_synthase_alpha" ;
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  up:database database:FunFam ;
  rdfs:comment "Tryptophan synthase alpha chain" ;
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  rdfs:comment "Trp_synthase_alpha_AS" .
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  up:database database:NCBIfam ;
  rdfs:comment "trpA" ;
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  up:database database:PANTHER ;
  rdfs:comment "TRYPTOPHAN SYNTHASE, ALPHA CHAIN" ;
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  up:database database:Pfam ;
  rdfs:comment "Trp_syntA" ;
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  up:database database:SUPFAM ;
  rdfs:comment "Ribulose-phoshate binding barrel" ;
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  up:database database:PROSITE ;
  rdfs:comment "TRP_SYNTHASE_ALPHA" ;
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  up:database database:PDBsum .
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  up:fullName "Tryptophan synthase alpha chain" ;
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  rdf:subject <P0A877#SIP848A8BBA844D6B2A> ;
  rdf:predicate up:fullName ;
  rdf:object "Tryptophan synthase alpha chain" ;
  up:attribution <P0A877#attribution-F0D0349C5CA887EA0ABE6B1DD5D85970> .
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  rdf:subject <P0A877#SIP848A8BBA844D6B2A> ;
  rdf:predicate up:ecName ;
  rdf:object "4.2.1.20" ;
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  skos:prefLabel "trpA" ;
  up:locusName "b1260" ,
    "JW1252" .
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  rdf:subject <P0A877#gene-MD5E67DF4CF3FD4B30973E9497BE52C626B> ;
  rdf:predicate skos:prefLabel ;
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  rdfs:comment "The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate." .
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  rdf:predicate up:annotation ;
  rdf:object <P0A877#SIPBD2A8B8DE6415241> ;
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  rdfs:comment "Tetramer of two alpha and two beta chains." .
<P0A877#SIP17E3D3C3D2709212> a up:Similarity_Annotation ;
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  rdf:subject <P0A877#SIP17E3D3C3D2709212> ;
  rdf:predicate rdfs:comment ;
  rdf:object "Belongs to the TrpA family." ;
  up:attribution <P0A877#attribution-F0D0349C5CA887EA0ABE6B1DD5D85970> .
annotation:PRO_0000098778 a up:Chain_Annotation ;
  rdfs:comment "Tryptophan synthase alpha chain" ;
  up:mass 28724 ;
  up:range range:22571054811002670tt1tt268 .
range:22571054811002670tt1tt268 a faldo:Region ;
  faldo:begin position:22571054811002670tt1 ;
  faldo:end position:22571054811002670tt268 .
position:22571054811002670tt1 a faldo:Position ,
    faldo:ExactPosition ;
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  faldo:reference isoform:P0A877-1 .
position:22571054811002670tt268 a faldo:Position ,
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  faldo:position 268 ;
  faldo:reference isoform:P0A877-1 .
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  rdfs:comment "Proton acceptor" ;
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range:22571054811002670tt49tt49 a faldo:Region ;
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  faldo:end position:22571054811002670tt49 .
position:22571054811002670tt49 a faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 49 ;
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  rdf:subject <P0A877> ;
  rdf:predicate up:annotation ;
  rdf:object <P0A877#SIP8BCAB65B70F64EE3> ;
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  rdfs:comment "Proton acceptor" ;
  up:range range:22571054811002670tt60tt60 .
range:22571054811002670tt60tt60 a faldo:Region ;
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  faldo:end position:22571054811002670tt60 .
position:22571054811002670tt60 a faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 60 ;
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  rdf:subject <P0A877> ;
  rdf:predicate up:annotation ;
  rdf:object <P0A877#SIPFDDBDD06FE479DD7> ;
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  rdfs:comment "In mutant TrpA46-Asp-PR3." ;
  up:substitution "IAGFWYFRPGSGKSSD" ;
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range:22571054811002670tt209tt224 a faldo:Region ;
  faldo:begin position:22571054811002670tt209 ;
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  up:attribution <P0A877#attribution-B1DC8963DBBAB97CFFF791B59ED92648> .
<P0A877#SIPFDB739118BBD2C01> a up:Beta_Strand_Annotation ;
  up:range range:22571054811002670tt229tt233 .
range:22571054811002670tt229tt233 a faldo:Region ;
  faldo:begin position:22571054811002670tt229 ;
  faldo:end position:22571054811002670tt233 .
position:22571054811002670tt229 a faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 229 ;
  faldo:reference isoform:P0A877-1 .
position:22571054811002670tt233 a faldo:Position ,
    faldo:ExactPosition ;
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  faldo:reference isoform:P0A877-1 .
<#_kb.P0A877_up.annotation_708FFABBDD257C52> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:annotation ;
  rdf:object <P0A877#SIPFDB739118BBD2C01> ;
  up:attribution <P0A877#attribution-B1DC8963DBBAB97CFFF791B59ED92648> .
<P0A877#SIPE8B1F010833DB3ED> a up:Helix_Annotation ;
  up:range range:22571054811002670tt236tt242 .
range:22571054811002670tt236tt242 a faldo:Region ;
  faldo:begin position:22571054811002670tt236 ;
  faldo:end position:22571054811002670tt242 .
position:22571054811002670tt236 a faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 236 ;
  faldo:reference isoform:P0A877-1 .
position:22571054811002670tt242 a faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 242 ;
  faldo:reference isoform:P0A877-1 .
<#_kb.P0A877_up.annotation_204A309DCAB14410> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:annotation ;
  rdf:object <P0A877#SIPE8B1F010833DB3ED> ;
  up:attribution <P0A877#attribution-B1DC8963DBBAB97CFFF791B59ED92648> .
<P0A877#SIPAEFB243E107BA87E> a up:Turn_Annotation ;
  up:range range:22571054811002670tt244tt246 .
range:22571054811002670tt244tt246 a faldo:Region ;
  faldo:begin position:22571054811002670tt244 ;
  faldo:end position:22571054811002670tt246 .
position:22571054811002670tt244 a faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 244 ;
  faldo:reference isoform:P0A877-1 .
position:22571054811002670tt246 a faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 246 ;
  faldo:reference isoform:P0A877-1 .
<#_kb.P0A877_up.annotation_16AB3D3CEDEA141C> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:annotation ;
  rdf:object <P0A877#SIPAEFB243E107BA87E> ;
  up:attribution <P0A877#attribution-25CB39CBF10A0405AF96428608F4CDD7> .
<P0A877#SIP3F140CE81C4F0456> a up:Helix_Annotation ;
  up:range range:22571054811002670tt248tt264 .
range:22571054811002670tt248tt264 a faldo:Region ;
  faldo:begin position:22571054811002670tt248 ;
  faldo:end position:22571054811002670tt264 .
position:22571054811002670tt248 a faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 248 ;
  faldo:reference isoform:P0A877-1 .
position:22571054811002670tt264 a faldo:Position ,
    faldo:ExactPosition ;
  faldo:position 264 ;
  faldo:reference isoform:P0A877-1 .
<#_kb.P0A877_up.annotation_03B247A8A25DC2F3> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:annotation ;
  rdf:object <P0A877#SIP3F140CE81C4F0456> ;
  up:attribution <P0A877#attribution-B1DC8963DBBAB97CFFF791B59ED92648> .
<#_kb.P0A877_up.classifiedWith_obo.GO_0005737> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0005737 ;
  up:attribution <P0A877#attribution-EF04AA991ADAD7D1BA69083572B95C8C> .
<#_kb.P0A877_up.classifiedWith_obo.GO_0005829> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0005829 ;
  up:attribution <P0A877#attribution-64F920643AF952E2DC410BAF9E816C1B> .
<#_kb.P0A877_up.classifiedWith_obo.GO_0016829> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0016829 ;
  up:attribution <P0A877#attribution-64F920643AF952E2DC410BAF9E816C1B> .
<#_kb.P0A877_up.classifiedWith_obo.GO_0060090> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0060090 ;
  up:attribution <P0A877#attribution-902B99A5CB894F61C8E1E96A6966117A> .
<#_kb.P0A877_up.classifiedWith_obo.GO_0004834> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0004834 ;
  up:attribution <P0A877#attribution-8AEC0CC661531CFE2FAE4F290FCF9B78> .
<#_kb.P0A877_up.classifiedWith_obo.GO_0009073> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0009073 ;
  up:attribution <P0A877#attribution-46DFE6258B75F14DED0B4394ED9C4496> .
<#_kb.P0A877_up.classifiedWith_obo.GO_0000162> a rdf:Statement ;
  rdf:subject <P0A877> ;
  rdf:predicate up:classifiedWith ;
  rdf:object go:0000162 ;
  up:attribution <P0A877#attribution-7CA1B065D37E97A7AF83A2F61C196FBA> .
isoform:P0A877-1 a up:Simple_Sequence ;
  up:modified "1986-07-21"^^xsd:date ;
  up:version 1 ;
  up:mass 28724 ;
  up:md5Checksum "1f1188d5fb1c600b0f1c9e3dd8f05eb8" ;
  rdf:value "MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAGADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMYANLVFNKGIDEFYAQCEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADDDLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPDQVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS" .
<P0A877#attribution-EF04AA991ADAD7D1BA69083572B95C8C> dcterms:creator <http://purl.uniprot.org/goa-projects/EcoliWiki> ;
  up:manual true ;
  up:evidence ECO:0000314 .
<P0A877#attribution-64F920643AF952E2DC410BAF9E816C1B> dcterms:creator <http://purl.uniprot.org/goa-projects/EcoCyc> ;
  up:manual true ;
  up:evidence ECO:0000314 .
<P0A877#attribution-902B99A5CB894F61C8E1E96A6966117A> dcterms:creator <http://purl.uniprot.org/goa-projects/DisProt> ;
  up:manual true ;
  up:evidence ECO:0000269 .
<P0A877#attribution-8AEC0CC661531CFE2FAE4F290FCF9B78> dcterms:creator <http://purl.uniprot.org/goa-projects/UniProtKB-UniRule> ;
  up:evidence ECO:0007669 .
<P0A877#attribution-46DFE6258B75F14DED0B4394ED9C4496> dcterms:creator <http://purl.uniprot.org/goa-projects/EcoliWiki> ;
  up:manual true ;
  up:evidence ECO:0000315 .
<P0A877#attribution-7CA1B065D37E97A7AF83A2F61C196FBA> dcterms:creator <http://purl.uniprot.org/goa-projects/ComplexPortal> ;
  up:manual true ;
  up:evidence ECO:0000314 .
<P0A877#attribution-F0D0349C5CA887EA0ABE6B1DD5D85970> up:manual true ;
  up:evidence ECO:0000255 ;
  up:source <https://purl.expasy.org/hamap/rule/MF_00131> .
<P0A877#attribution-DD05343EF71430E56BB7D9FDB15AA799> up:evidence ECO:0007829 ;
  up:source <http://rdf.wwpdb.org/pdb/1V7Y> .
<P0A877#attribution-25CB39CBF10A0405AF96428608F4CDD7> up:evidence ECO:0007829 ;
  up:source <http://rdf.wwpdb.org/pdb/1WQ5> .
<P0A877#attribution-B1DC8963DBBAB97CFFF791B59ED92648> up:evidence ECO:0007829 ;
  up:source <http://rdf.wwpdb.org/pdb/1XCF> .