{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P0A7D7","secondaryAccessions":["P21155"],"uniProtkbId":"PUR7_ECOLI","entryAudit":{"firstPublicDate":"2005-06-07","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2005-06-07","entryVersion":151,"sequenceVersion":1},"annotationScore":4.0,"organism":{"scientificName":"Escherichia coli (strain K12)","taxonId":83333,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"value":"Phosphoribosylaminoimidazole-succinocarboxamide synthase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"1534690"}],"value":"6.3.2.6"}]},"alternativeNames":[{"fullName":{"value":"SAICAR synthetase"}}]},"genes":[{"geneName":{"value":"purC"},"orderedLocusNames":[{"value":"b2476"},{"value":"JW2461"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"1534690"}],"value":"Converts 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) to 4-(N-succinylcarboxamide)-5-aminoimidazole ribonucleotide (SAICAR)"}],"commentType":"FUNCTION"},{"commentType":"CATALYTIC ACTIVITY","reaction":{"name":"5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + phosphate + 2 H(+)","reactionCrossReferences":[{"database":"Rhea","id":"RHEA:22628"},{"database":"ChEBI","id":"CHEBI:15378"},{"database":"ChEBI","id":"CHEBI:29991"},{"database":"ChEBI","id":"CHEBI:30616"},{"database":"ChEBI","id":"CHEBI:43474"},{"database":"ChEBI","id":"CHEBI:58443"},{"database":"ChEBI","id":"CHEBI:77657"},{"database":"ChEBI","id":"CHEBI:456216"}],"ecNumber":"6.3.2.6","evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"1534690"}]}},{"texts":[{"value":"Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2"}],"commentType":"PATHWAY"},{"texts":[{"value":"Homotrimer"}],"commentType":"SUBUNIT"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Belongs to the SAICAR synthetase family"}],"commentType":"SIMILARITY"}],"features":[{"type":"Chain","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":237,"modifier":"EXACT"}},"description":"Phosphoribosylaminoimidazole-succinocarboxamide synthase","featureId":"PRO_0000100825"},{"type":"Beta strand","location":{"start":{"value":5,"modifier":"EXACT"},"end":{"value":9,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":11,"modifier":"EXACT"},"end":{"value":17,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":23,"modifier":"EXACT"},"end":{"value":28,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":30,"modifier":"EXACT"},"end":{"value":32,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Turn","location":{"start":{"value":35,"modifier":"EXACT"},"end":{"value":38,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":39,"modifier":"EXACT"},"end":{"value":42,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQS"}]},{"type":"Helix","location":{"start":{"value":46,"modifier":"EXACT"},"end":{"value":63,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":70,"modifier":"EXACT"},"end":{"value":73,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":75,"modifier":"EXACT"},"end":{"value":82,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":88,"modifier":"EXACT"},"end":{"value":96,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Helix","location":{"start":{"value":99,"modifier":"EXACT"},"end":{"value":105,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":112,"modifier":"EXACT"},"end":{"value":122,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Helix","location":{"start":{"value":125,"modifier":"EXACT"},"end":{"value":127,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Helix","location":{"start":{"value":134,"modifier":"EXACT"},"end":{"value":139,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Helix","location":{"start":{"value":145,"modifier":"EXACT"},"end":{"value":168,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":171,"modifier":"EXACT"},"end":{"value":183,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":186,"modifier":"EXACT"},"end":{"value":191,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Beta strand","location":{"start":{"value":197,"modifier":"EXACT"},"end":{"value":202,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Turn","location":{"start":{"value":203,"modifier":"EXACT"},"end":{"value":205,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Helix","location":{"start":{"value":212,"modifier":"EXACT"},"end":{"value":215,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]},{"type":"Helix","location":{"start":{"value":221,"modifier":"EXACT"},"end":{"value":232,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0007829","source":"PDB","id":"2GQR"}]}],"keywords":[{"id":"KW-0002","category":"Technical term","name":"3D-structure"},{"id":"KW-0067","category":"Ligand","name":"ATP-binding"},{"id":"KW-0903","category":"Technical term","name":"Direct protein sequencing"},{"id":"KW-0436","category":"Molecular function","name":"Ligase"},{"id":"KW-0547","category":"Ligand","name":"Nucleotide-binding"},{"id":"KW-0658","category":"Biological process","name":"Purine biosynthesis"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"}],"references":[{"referenceNumber":1,"citation":{"id":"2120198","citationType":"journal article","authors":["Tiedemann A.A.","Demarini D.J.","Parker J.","Smith J.M."],"citationCrossReferences":[{"database":"PubMed","id":"2120198"},{"database":"DOI","id":"10.1128/jb.172.10.6035-6041.1990"}],"title":"DNA sequence of the purC gene encoding 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide synthetase and organization of the dapA-purC region of Escherichia coli K-12.","publicationDate":"1990","journal":"J. Bacteriol.","firstPage":"6035","lastPage":"6041","volume":"172"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]","PARTIAL PROTEIN SEQUENCE"],"referenceComments":[{"value":"K12","type":"STRAIN"}]},{"referenceNumber":2,"citation":{"id":"9205837","citationType":"journal article","authors":["Yamamoto Y.","Aiba H.","Baba T.","Hayashi K.","Inada T.","Isono K.","Itoh T.","Kimura S.","Kitagawa M.","Makino K.","Miki T.","Mitsuhashi N.","Mizobuchi K.","Mori H.","Nakade S.","Nakamura Y.","Nashimoto H.","Oshima T.","Oyama S.","Saito N.","Sampei G.","Satoh Y.","Sivasundaram S.","Tagami H.","Takahashi H.","Takeda J.","Takemoto K.","Uehara K.","Wada C.","Yamagata S.","Horiuchi T."],"citationCrossReferences":[{"database":"PubMed","id":"9205837"},{"database":"DOI","id":"10.1093/dnares/4.2.91"}],"title":"Construction of a contiguous 874-kb sequence of the Escherichia coli-K12 genome corresponding to 50.0-68.8 min on the linkage map and analysis of its sequence features.","publicationDate":"1997","journal":"DNA Res.","firstPage":"91","lastPage":"113","volume":"4"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / W3110 / ATCC 27325 / DSM 5911","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"9278503","citationType":"journal article","authors":["Blattner F.R.","Plunkett G. III","Bloch C.A.","Perna N.T.","Burland V.","Riley M.","Collado-Vides J.","Glasner J.D.","Rode C.K.","Mayhew G.F.","Gregor J.","Davis N.W.","Kirkpatrick H.A.","Goeden M.A.","Rose D.J.","Mau B.","Shao Y."],"citationCrossReferences":[{"database":"PubMed","id":"9278503"},{"database":"DOI","id":"10.1126/science.277.5331.1453"}],"title":"The complete genome sequence of Escherichia coli K-12.","publicationDate":"1997","journal":"Science","firstPage":"1453","lastPage":"1462","volume":"277"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / MG1655 / ATCC 47076","type":"STRAIN"}]},{"referenceNumber":4,"citation":{"id":"16738553","citationType":"journal article","authors":["Hayashi K.","Morooka N.","Yamamoto Y.","Fujita K.","Isono K.","Choi S.","Ohtsubo E.","Baba T.","Wanner B.L.","Mori H.","Horiuchi T."],"citationCrossReferences":[{"database":"PubMed","id":"16738553"},{"database":"DOI","id":"10.1038/msb4100049"}],"title":"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.","publicationDate":"2006","journal":"Mol. Syst. Biol.","firstPage":"E1","lastPage":"E5","volume":"2"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"K12 / W3110 / ATCC 27325 / DSM 5911","type":"STRAIN"}]},{"referenceNumber":5,"citation":{"id":"1885529","citationType":"journal article","authors":["Bouvier J.","Pugsley A.P.","Stragier P."],"citationCrossReferences":[{"database":"PubMed","id":"1885529"},{"database":"DOI","id":"10.1128/jb.173.17.5523-5531.1991"}],"title":"A gene for a new lipoprotein in the dapA-purC interval of the Escherichia coli chromosome.","publicationDate":"1991","journal":"J. Bacteriol.","firstPage":"5523","lastPage":"5531","volume":"173"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-28"],"referenceComments":[{"value":"K12","type":"STRAIN"}]},{"referenceNumber":6,"citation":{"id":"9298646","citationType":"journal article","authors":["Link A.J.","Robison K.","Church G.M."],"citationCrossReferences":[{"database":"PubMed","id":"9298646"},{"database":"DOI","id":"10.1002/elps.1150180807"}],"title":"Comparing the predicted and observed properties of proteins encoded in the genome of Escherichia coli K-12.","publicationDate":"1997","journal":"Electrophoresis","firstPage":"1259","lastPage":"1313","volume":"18"},"referencePositions":["PROTEIN SEQUENCE OF 1-12"],"referenceComments":[{"value":"K12 / EMG2","type":"STRAIN"}]},{"referenceNumber":7,"citation":{"id":"1534690","citationType":"journal article","authors":["Meyer E.","Leonard N.J.","Bhat B.","Stubbe J.","Smith J.M."],"citationCrossReferences":[{"database":"PubMed","id":"1534690"},{"database":"DOI","id":"10.1021/bi00136a016"}],"title":"Purification and characterization of the purE, purK, and purC gene products: identification of a previously unrecognized energy requirement in the purine biosynthetic pathway.","publicationDate":"1992","journal":"Biochemistry","firstPage":"5022","lastPage":"5032","volume":"31"},"referencePositions":["CATALYTIC ACTIVITY","FUNCTION"]},{"referenceNumber":8,"citation":{"id":"9298644","citationType":"journal article","authors":["VanBogelen R.A.","Abshire K.Z.","Moldover B.","Olson E.R.","Neidhardt F.C."],"citationCrossReferences":[{"database":"PubMed","id":"9298644"},{"database":"DOI","id":"10.1002/elps.1150180805"}],"title":"Escherichia coli proteome analysis using the gene-protein database.","publicationDate":"1997","journal":"Electrophoresis","firstPage":"1243","lastPage":"1251","volume":"18"},"referencePositions":["IDENTIFICATION BY 2D-GEL"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"M33928","properties":[{"key":"ProteinId","value":"AAA24448.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"U00096","properties":[{"key":"ProteinId","value":"AAC75529.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"AP009048","properties":[{"key":"ProteinId","value":"BAA16353.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"X57402","properties":[{"key":"ProteinId","value":"CAA40662.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"C36146","properties":[{"key":"EntryName","value":"C36146"}]},{"database":"RefSeq","id":"NP_416971.1","properties":[{"key":"NucleotideSequenceId","value":"NC_000913.3"}]},{"database":"RefSeq","id":"WP_001295467.1","properties":[{"key":"NucleotideSequenceId","value":"NZ_CP009789.1"}]},{"database":"PDB","id":"2GQR","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"2.00 A"},{"key":"Chains","value":"A/B=1-237"}]},{"database":"PDB","id":"2GQS","properties":[{"key":"Method","value":"X-ray"},{"key":"Resolution","value":"2.05 A"},{"key":"Chains","value":"A/B=1-237"}]},{"database":"PDBsum","id":"2GQR","properties":[{"key":"Description","value":"-"}]},{"database":"PDBsum","id":"2GQS","properties":[{"key":"Description","value":"-"}]},{"database":"AlphaFoldDB","id":"P0A7D7","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P0A7D7","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"4261983","properties":[{"key":"Interactions","value":"55"}]},{"database":"BioGRID","id":"851296","properties":[{"key":"Interactions","value":"7"}]},{"database":"DIP","id":"DIP-35900N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P0A7D7","properties":[{"key":"Number of interactors","value":"776"}]},{"database":"IntAct","id":"P0A7D7","properties":[{"key":"Interactions","value":"17"}]},{"database":"STRING","id":"511145.b2476","properties":[{"key":"Description","value":"-"}]},{"database":"jPOST","id":"P0A7D7","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"511145-b2476","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblBacteria","id":"AAC75529","properties":[{"key":"ProteinId","value":"AAC75529"},{"key":"GeneId","value":"b2476"}]},{"database":"GeneID","id":"89517285","properties":[{"key":"Description","value":"-"}]},{"database":"GeneID","id":"946957","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecj:JW2461","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"eco:b2476","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"ecoc:C3026_13740","properties":[{"key":"Description","value":"-"}]},{"database":"PATRIC","id":"fig|1411691.4.peg.4263","properties":[{"key":"GeneDesignation","value":"-"}]},{"database":"EchoBASE","id":"EB0784","properties":[{"key":"Description","value":"-"}]},{"database":"eggNOG","id":"COG0152","properties":[{"key":"ToxonomicScope","value":"Bacteria"}]},{"database":"HOGENOM","id":"CLU_061495_2_1_6","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P0A7D7","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"EFCYKND","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"9801549at2","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P0A7D7","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"EcoCyc:SAICARSYN-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"BioCyc","id":"MetaCyc:SAICARSYN-MONOMER","properties":[{"key":"Description","value":"-"}]},{"database":"BRENDA","id":"6.3.2.6","properties":[{"key":"OrganismId","value":"2026"}]},{"database":"UniPathway","id":"UPA00074","properties":[{"key":"RectionId","value":"UER00131"}]},{"database":"EvolutionaryTrace","id":"P0A7D7","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:P0A7D7","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000000625","properties":[{"key":"Component","value":"Chromosome"}]},{"database":"AbasyAtlas","id":"P0A7D7","properties":[{"key":"Description","value":"-"}]},{"database":"GO","id":"GO:0005829","properties":[{"key":"GoTerm","value":"C:cytosol"},{"key":"GoEvidenceType","value":"IDA:EcoCyc"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"15911532"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"17309111"},{"evidenceCode":"ECO:0000314","source":"PubMed","id":"18304323"}]},{"database":"GO","id":"GO:0016020","properties":[{"key":"GoTerm","value":"C:membrane"},{"key":"GoEvidenceType","value":"HDA:UniProtKB"}],"evidences":[{"evidenceCode":"ECO:0007005","source":"PubMed","id":"16858726"}]},{"database":"GO","id":"GO:0097216","properties":[{"key":"GoTerm","value":"F:guanosine tetraphosphate binding"},{"key":"GoEvidenceType","value":"IDA:EcoCyc"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"30559427"}]},{"database":"GO","id":"GO:0004639","properties":[{"key":"GoTerm","value":"F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"},{"key":"GoEvidenceType","value":"IDA:EcoCyc"}],"evidences":[{"evidenceCode":"ECO:0000314","source":"PubMed","id":"1534690"}]},{"database":"GO","id":"GO:0006189","properties":[{"key":"GoTerm","value":"P:'de novo' IMP biosynthetic process"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0009236","properties":[{"key":"GoTerm","value":"P:cobalamin biosynthetic process"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"CDD","id":"cd01415","properties":[{"key":"EntryName","value":"SAICAR_synt_PurC"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.200.20:FF:000086","properties":[{"key":"EntryName","value":"Phosphoribosylaminoimidazole-succinocarboxamide synthase"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"3.30.470.20:FF:000006","properties":[{"key":"EntryName","value":"Phosphoribosylaminoimidazole-succinocarboxamide synthase"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.470.20","properties":[{"key":"EntryName","value":"ATP-grasp fold, B domain"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"3.30.200.20","properties":[{"key":"EntryName","value":"Phosphorylase Kinase, domain 1"},{"key":"MatchStatus","value":"1"}]},{"database":"HAMAP","id":"MF_00137","properties":[{"key":"EntryName","value":"SAICAR_synth"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR028923","properties":[{"key":"EntryName","value":"SAICAR_synt/ADE2_N"}]},{"database":"InterPro","id":"IPR033934","properties":[{"key":"EntryName","value":"SAICAR_synt_PurC"}]},{"database":"InterPro","id":"IPR001636","properties":[{"key":"EntryName","value":"SAICAR_synth"}]},{"database":"InterPro","id":"IPR018236","properties":[{"key":"EntryName","value":"SAICAR_synthetase_CS"}]},{"database":"NCBIfam","id":"TIGR00081","properties":[{"key":"EntryName","value":"purC"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43599","properties":[{"key":"EntryName","value":"MULTIFUNCTIONAL PROTEIN ADE2"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR43599:SF3","properties":[{"key":"EntryName","value":"SI:DKEY-6E2.2"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01259","properties":[{"key":"EntryName","value":"SAICAR_synt"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56104","properties":[{"key":"EntryName","value":"SAICAR synthase-like"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS01057","properties":[{"key":"EntryName","value":"SAICAR_SYNTHETASE_1"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS01058","properties":[{"key":"EntryName","value":"SAICAR_SYNTHETASE_2"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFDRKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLVKRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKANDVLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSLGGLIEAYEAVARRLGVQLD","length":237,"molWeight":26995,"crc64":"E5D0E69E84E35C97","md5":"B3550340B861A18DBBD2E853824EB6EA"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"CATALYTIC ACTIVITY":1,"PATHWAY":1,"SUBUNIT":1,"SIMILARITY":1},"countByFeatureType":{"Chain":1,"Beta strand":12,"Turn":2,"Helix":7},"uniParcId":"UPI0000132A8F"}}