{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P0A6I6","secondaryAccessions":["P23875","Q2M7U8"],"uniProtkbId":"COAD_ECOLI","entryAudit":{"firstPublicDate":"2005-03-29","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2005-03-29","entryVersion":156,"sequenceVersion":1},"annotationScore":5.0,"organism":{"scientificName":"Escherichia coli (strain K12)","taxonId":83333,"lineage":["Bacteria","Pseudomonadati","Pseudomonadota","Gammaproteobacteria","Enterobacterales","Enterobacteriaceae","Escherichia"]},"proteinExistence":"1: Evidence at protein level","proteinDescription":{"recommendedName":{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00151"},{"evidenceCode":"ECO:0000303","source":"PubMed","id":"10480925"}],"value":"Phosphopantetheine adenylyltransferase"},"ecNumbers":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00151"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10480925"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"17873050"}],"value":"2.7.7.3"}]},"alternativeNames":[{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00151"}],"value":"Dephospho-CoA pyrophosphorylase"}},{"fullName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00151"}],"value":"Pantetheine-phosphate adenylyltransferase"},"shortNames":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00151"},{"evidenceCode":"ECO:0000303","source":"PubMed","id":"10480925"}],"value":"PPAT"}]}]},"genes":[{"geneName":{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00151"},{"evidenceCode":"ECO:0000303","source":"PubMed","id":"10480925"}],"value":"coaD"},"synonyms":[{"evidences":[{"evidenceCode":"ECO:0000303","source":"PubMed","id":"1577693"}],"value":"kdtB"},{"value":"yicA"}],"orderedLocusNames":[{"value":"b3634"},{"value":"JW3609"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000255","source":"HAMAP-Rule","id":"MF_00151"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"10480925"},{"evidenceCode":"ECO:0000269","source":"PubMed","id":"17873050"}],"value":"Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (PubMed:10480925, PubMed:17873050). 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