{"entryType":"UniProtKB reviewed (Swiss-Prot)","primaryAccession":"P06125","uniProtkbId":"VIT5_CAEEL","entryAudit":{"firstPublicDate":"1988-01-01","lastAnnotationUpdateDate":"2026-09-02","lastSequenceUpdateDate":"2008-07-22","entryVersion":181,"sequenceVersion":2},"annotationScore":3.0,"organism":{"scientificName":"Caenorhabditis elegans","taxonId":6239,"lineage":["Eukaryota","Metazoa","Ecdysozoa","Nematoda","Chromadorea","Rhabditida","Rhabditina","Rhabditomorpha","Rhabditoidea","Rhabditidae","Peloderinae","Caenorhabditis"]},"proteinExistence":"2: Evidence at transcript level","proteinDescription":{"recommendedName":{"fullName":{"value":"Vitellogenin-5"}},"flag":"Precursor"},"genes":[{"geneName":{"value":"vit-5"},"orfNames":[{"value":"C04F6.1"}]}],"comments":[{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"26671266"},{"evidenceCode":"ECO:0000305"}],"value":"Precursor of the egg-yolk proteins that are sources of nutrients during embryonic development (Probable). Together with other vitellogenins, may play a role in modulating life-span, acting via induction of autophagy and lysosomal lipolysis (PubMed:26671266)"}],"commentType":"FUNCTION"},{"commentType":"SUBCELLULAR LOCATION","subcellularLocations":[{"location":{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"26671266"}],"value":"Secreted","id":"SL-0243"}}]},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"26671266"}],"value":"Expressed in the intestine of adult hermaphrodites"}],"commentType":"TISSUE SPECIFICITY"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305"}],"value":"Vitellogenin 5 undergoes little if any processing before being packaged into yolk platelets"}],"commentType":"PTM"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000269","source":"PubMed","id":"26671266"}],"value":"Simultaneous RNAi-mediated knockdown of vitellogenins vit-1, vit-2, vit-3, vit-4 and vit-5 increases life span, causes accumulation of neutral lipid and an increase in lgg-1 foci in the proximal intestine; however, does not affect fertility or pharyngeal pumping rates (PubMed:26671266). Expression of transcription factors pha-4 and daf-16 are increased (PubMed:26671266)"}],"commentType":"DISRUPTION PHENOTYPE"},{"texts":[{"evidences":[{"evidenceCode":"ECO:0000305","source":"PubMed","id":"26671266"}],"value":"High sequence similarity with other vitellogenin genes means that assigning functions to individual proteins is difficult; authors sometimes refer to VITs or vitellogenins"}],"commentType":"CAUTION"}],"features":[{"type":"Signal","location":{"start":{"value":1,"modifier":"EXACT"},"end":{"value":15,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255"}]},{"type":"Chain","location":{"start":{"value":16,"modifier":"EXACT"},"end":{"value":1603,"modifier":"EXACT"}},"description":"Vitellogenin-5","featureId":"PRO_0000041536"},{"type":"Domain","location":{"start":{"value":24,"modifier":"EXACT"},"end":{"value":685,"modifier":"EXACT"}},"description":"Vitellogenin","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00557"}]},{"type":"Domain","location":{"start":{"value":1306,"modifier":"EXACT"},"end":{"value":1475,"modifier":"EXACT"}},"description":"VWFD","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00580"}]},{"type":"Region","location":{"start":{"value":1492,"modifier":"EXACT"},"end":{"value":1513,"modifier":"EXACT"}},"description":"Disordered","evidences":[{"evidenceCode":"ECO:0000256","source":"SAM","id":"MobiDB-lite"}]},{"type":"Disulfide bond","location":{"start":{"value":1308,"modifier":"EXACT"},"end":{"value":1438,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00580"}]},{"type":"Disulfide bond","location":{"start":{"value":1330,"modifier":"EXACT"},"end":{"value":1474,"modifier":"EXACT"}},"description":"","evidences":[{"evidenceCode":"ECO:0000255","source":"PROSITE-ProRule","id":"PRU00580"}]},{"type":"Sequence conflict","location":{"start":{"value":45,"modifier":"EXACT"},"end":{"value":45,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"A","alternativeSequences":["R"]}},{"type":"Sequence conflict","location":{"start":{"value":169,"modifier":"EXACT"},"end":{"value":169,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"L","alternativeSequences":["V"]}},{"type":"Sequence conflict","location":{"start":{"value":183,"modifier":"EXACT"},"end":{"value":187,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"EVAYT","alternativeSequences":["RSRLH"]}},{"type":"Sequence conflict","location":{"start":{"value":391,"modifier":"EXACT"},"end":{"value":392,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"TL","alternativeSequences":["SI"]}},{"type":"Sequence conflict","location":{"start":{"value":614,"modifier":"EXACT"},"end":{"value":614,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"N","alternativeSequences":["H"]}},{"type":"Sequence conflict","location":{"start":{"value":689,"modifier":"EXACT"},"end":{"value":689,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"F","alternativeSequences":["L"]}},{"type":"Sequence conflict","location":{"start":{"value":883,"modifier":"EXACT"},"end":{"value":885,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"RFW","alternativeSequences":["PLL"]}},{"type":"Sequence conflict","location":{"start":{"value":1264,"modifier":"EXACT"},"end":{"value":1269,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"YMNMTI","alternativeSequences":["SHEHDH"]}},{"type":"Sequence conflict","location":{"start":{"value":1281,"modifier":"EXACT"},"end":{"value":1281,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"V","alternativeSequences":["A"]}},{"type":"Sequence conflict","location":{"start":{"value":1319,"modifier":"EXACT"},"end":{"value":1319,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"D","alternativeSequences":["H"]}},{"type":"Sequence conflict","location":{"start":{"value":1476,"modifier":"EXACT"},"end":{"value":1478,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"VEN","alternativeSequences":["FEF"]}},{"type":"Sequence conflict","location":{"start":{"value":1517,"modifier":"EXACT"},"end":{"value":1517,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"K","alternativeSequences":["E"]}},{"type":"Sequence conflict","location":{"start":{"value":1565,"modifier":"EXACT"},"end":{"value":1569,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"SKNAR","alternativeSequences":["RQERS"]}},{"type":"Sequence conflict","location":{"start":{"value":1573,"modifier":"EXACT"},"end":{"value":1576,"modifier":"EXACT"}},"description":"in Ref. 1; CAA26849","evidences":[{"evidenceCode":"ECO:0000305"}],"alternativeSequence":{"originalSequence":"KEAR","alternativeSequences":["QGSS"]}}],"keywords":[{"id":"KW-1015","category":"PTM","name":"Disulfide bond"},{"id":"KW-1185","category":"Technical term","name":"Reference proteome"},{"id":"KW-0964","category":"Cellular component","name":"Secreted"},{"id":"KW-0732","category":"Domain","name":"Signal"},{"id":"KW-0758","category":"Molecular function","name":"Storage protein"}],"references":[{"referenceNumber":1,"citation":{"id":"3855245","citationType":"journal article","authors":["Spieth J.","Denison K.","Zucker E.","Blumenthal T."],"citationCrossReferences":[{"database":"PubMed","id":"3855245"},{"database":"DOI","id":"10.1093/nar/13.19.7129"}],"title":"The nucleotide sequence of a nematode vitellogenin gene.","publicationDate":"1985","journal":"Nucleic Acids Res.","firstPage":"7129","lastPage":"7138","volume":"13"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA]"]},{"referenceNumber":2,"citation":{"id":"9851916","citationType":"journal article","authoringGroup":["The C. elegans sequencing consortium"],"citationCrossReferences":[{"database":"PubMed","id":"9851916"},{"database":"DOI","id":"10.1126/science.282.5396.2012"}],"title":"Genome sequence of the nematode C. elegans: a platform for investigating biology.","publicationDate":"1998","journal":"Science","firstPage":"2012","lastPage":"2018","volume":"282"},"referencePositions":["NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]"],"referenceComments":[{"value":"Bristol N2","type":"STRAIN"}]},{"referenceNumber":3,"citation":{"id":"4022780","citationType":"journal article","authors":["Spieth J.","Denison K.","Kirtland S.","Cane J.","Blumenthal T."],"citationCrossReferences":[{"database":"PubMed","id":"4022780"},{"database":"DOI","id":"10.1093/nar/13.14.5283"}],"title":"The C. elegans vitellogenin genes: short sequence repeats in the promoter regions and homology to the vertebrate genes.","publicationDate":"1985","journal":"Nucleic Acids Res.","firstPage":"5283","lastPage":"5295","volume":"13"},"referencePositions":["NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-24"]},{"referenceNumber":4,"citation":{"id":"26671266","citationType":"journal article","authors":["Seah N.E.","de Magalhaes Filho C.D.","Petrashen A.P.","Henderson H.R.","Laguer J.","Gonzalez J.","Dillin A.","Hansen M.","Lapierre L.R."],"citationCrossReferences":[{"database":"PubMed","id":"26671266"},{"database":"DOI","id":"10.1080/15548627.2015.1127464"}],"title":"Autophagy-mediated longevity is modulated by lipoprotein biogenesis.","publicationDate":"2016","journal":"Autophagy","firstPage":"261","lastPage":"272","volume":"12"},"referencePositions":["FUNCTION","SUBCELLULAR LOCATION","TISSUE SPECIFICITY","DISRUPTION PHENOTYPE"]}],"uniProtKBCrossReferences":[{"database":"EMBL","id":"X03044","properties":[{"key":"ProteinId","value":"CAA26849.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"FO080344","properties":[{"key":"ProteinId","value":"CCD63027.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"EMBL","id":"X02755","properties":[{"key":"ProteinId","value":"CAA26532.1"},{"key":"Status","value":"-"},{"key":"MoleculeType","value":"Genomic_DNA"}]},{"database":"PIR","id":"A03334","properties":[{"key":"EntryName","value":"VJKW5"}]},{"database":"PIR","id":"F89497","properties":[{"key":"EntryName","value":"F89497"}]},{"database":"RefSeq","id":"NP_508589.1","properties":[{"key":"NucleotideSequenceId","value":"NM_076188.7"}]},{"database":"AlphaFoldDB","id":"P06125","properties":[{"key":"Description","value":"-"}]},{"database":"SMR","id":"P06125","properties":[{"key":"Description","value":"-"}]},{"database":"BioGRID","id":"45570","properties":[{"key":"Interactions","value":"28"}]},{"database":"DIP","id":"DIP-25459N","properties":[{"key":"Description","value":"-"}]},{"database":"FunCoup","id":"P06125","properties":[{"key":"Number of interactors","value":"386"}]},{"database":"IntAct","id":"P06125","properties":[{"key":"Interactions","value":"1"}]},{"database":"STRING","id":"6239.C04F6.1.1","properties":[{"key":"Description","value":"-"}]},{"database":"iPTMnet","id":"P06125","properties":[{"key":"Description","value":"-"}]},{"database":"PaxDb","id":"6239-C04F6.1.1","properties":[{"key":"Description","value":"-"}]},{"database":"PeptideAtlas","id":"P06125","properties":[{"key":"Description","value":"-"}]},{"database":"EnsemblMetazoa","id":"C04F6.1.1","properties":[{"key":"ProteinId","value":"C04F6.1.1"},{"key":"GeneId","value":"WBGene00006929"}]},{"database":"GeneID","id":"180630","properties":[{"key":"Description","value":"-"}]},{"database":"KEGG","id":"cel:CELE_C04F6.1","properties":[{"key":"Description","value":"-"}]},{"database":"UCSC","id":"C04F6.1.1","properties":[{"key":"OrganismName","value":"c. elegans"}]},{"database":"AGR","id":"WB:WBGene00006929","properties":[{"key":"Description","value":"-"}]},{"database":"CTD","id":"180630","properties":[{"key":"Description","value":"-"}]},{"database":"WormBase","id":"C04F6.1","properties":[{"key":"ProteinId","value":"CE03921"},{"key":"GeneId","value":"WBGene00006929"},{"key":"GeneName","value":"vit-5"}]},{"database":"eggNOG","id":"KOG4338","properties":[{"key":"ToxonomicScope","value":"Eukaryota"}]},{"database":"HOGENOM","id":"CLU_003821_0_0_1","properties":[{"key":"Description","value":"-"}]},{"database":"InParanoid","id":"P06125","properties":[{"key":"Description","value":"-"}]},{"database":"OMA","id":"ENPMWHP","properties":[{"key":"Fingerprint","value":"-"}]},{"database":"OrthoDB","id":"5825149at2759","properties":[{"key":"Description","value":"-"}]},{"database":"PhylomeDB","id":"P06125","properties":[{"key":"Description","value":"-"}]},{"database":"SignaLink","id":"P06125","properties":[{"key":"Description","value":"-"}]},{"database":"PRO","id":"PR:P06125","properties":[{"key":"Description","value":"-"}]},{"database":"Proteomes","id":"UP000001940","properties":[{"key":"Component","value":"Chromosome X"}]},{"database":"Bgee","id":"WBGene00006929","properties":[{"key":"ExpressionPatterns","value":"Expressed in adult organism and 1 other cell type or tissue"}]},{"database":"GO","id":"GO:0005576","properties":[{"key":"GoTerm","value":"C:extracellular region"},{"key":"GoEvidenceType","value":"IEA:UniProtKB-SubCell"}]},{"database":"GO","id":"GO:0005319","properties":[{"key":"GoTerm","value":"F:lipid carrier activity"},{"key":"GoEvidenceType","value":"IBA:GO_Central"}]},{"database":"GO","id":"GO:0006869","properties":[{"key":"GoTerm","value":"P:lipid transport"},{"key":"GoEvidenceType","value":"IEA:InterPro"}]},{"database":"FunFam","id":"1.25.10.20:FF:000003","properties":[{"key":"EntryName","value":"Vitellogenin C"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.30.230.10:FF:000004","properties":[{"key":"EntryName","value":"Vitellogenin-1"},{"key":"MatchStatus","value":"1"}]},{"database":"FunFam","id":"2.20.80.10:FF:000004","properties":[{"key":"EntryName","value":"Vitellogenin-3"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.30.230.10","properties":[{"key":"EntryName","value":"Lipovitellin, beta-sheet shell regions, chain A"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"2.20.80.10","properties":[{"key":"EntryName","value":"Lipovitellin-phosvitin complex, chain A, domain 4"},{"key":"MatchStatus","value":"1"}]},{"database":"Gene3D","id":"1.25.10.20","properties":[{"key":"EntryName","value":"Vitellinogen, superhelical"},{"key":"MatchStatus","value":"1"}]},{"database":"InterPro","id":"IPR015819","properties":[{"key":"EntryName","value":"Lipid_transp_b-sht_shell"}]},{"database":"InterPro","id":"IPR011030","properties":[{"key":"EntryName","value":"Lipovitellin_superhlx_dom"}]},{"database":"InterPro","id":"IPR015816","properties":[{"key":"EntryName","value":"Vitellinogen_b-sht_N"}]},{"database":"InterPro","id":"IPR015255","properties":[{"key":"EntryName","value":"Vitellinogen_open_b-sht"}]},{"database":"InterPro","id":"IPR050733","properties":[{"key":"EntryName","value":"Vitellogenin/Apolipophorin"}]},{"database":"InterPro","id":"IPR001747","properties":[{"key":"EntryName","value":"Vitellogenin_M"}]},{"database":"InterPro","id":"IPR063611","properties":[{"key":"EntryName","value":"Vitellogenin_N"}]},{"database":"InterPro","id":"IPR001846","properties":[{"key":"EntryName","value":"VWF_type-D"}]},{"database":"PANTHER","id":"PTHR23345:SF8","properties":[{"key":"EntryName","value":"VITELLOGENIN-3-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"PANTHER","id":"PTHR23345","properties":[{"key":"EntryName","value":"VITELLOGENIN-RELATED"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF01347","properties":[{"key":"EntryName","value":"TPR_Vitellogenin"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF09172","properties":[{"key":"EntryName","value":"Vit_open_b-sht"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF29934","properties":[{"key":"EntryName","value":"Vitellogenin_N"},{"key":"MatchStatus","value":"1"}]},{"database":"Pfam","id":"PF00094","properties":[{"key":"EntryName","value":"VWD"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM01169","properties":[{"key":"EntryName","value":"DUF1943"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00638","properties":[{"key":"EntryName","value":"LPD_N"},{"key":"MatchStatus","value":"1"}]},{"database":"SMART","id":"SM00216","properties":[{"key":"EntryName","value":"VWD"},{"key":"MatchStatus","value":"1"}]},{"database":"SUPFAM","id":"SSF56968","properties":[{"key":"EntryName","value":"Lipovitellin-phosvitin complex, beta-sheet shell regions"},{"key":"MatchStatus","value":"2"}]},{"database":"SUPFAM","id":"SSF48431","properties":[{"key":"EntryName","value":"Lipovitellin-phosvitin complex, superhelical domain"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51211","properties":[{"key":"EntryName","value":"VITELLOGENIN"},{"key":"MatchStatus","value":"1"}]},{"database":"PROSITE","id":"PS51233","properties":[{"key":"EntryName","value":"VWFD"},{"key":"MatchStatus","value":"1"}]}],"sequence":{"value":"MKSIIIASLVALAIAASPALDRTFSPKSEYVYKFDGLLLSGLPTASSDASQTLISCRTRLQAVDDRYIHLQLTDIQYSASHIPQSEQWPKIESLEQRELSDEFKELLELPFRAQIRNGLISEIQFSSEDAEWSKNAKRSILNLFSLRKSAPVDEMNQDQKDMESDKDSLFFNVHEKTMEGDCEVAYTIVQEGEKTIYTKSVNFDKCITRPETAYGLRFGSECKECEKEGQFVKPQTVYTYTFKNEKLQESEVHSVYTLNVNGQEVVKSETRAKVTFVEESKINREIKKVSGPKEEIVYSMENEKLIEQFYQQGDKAEVNPFKAIEMEQKVEQLQEIFRQIQEHEQNTPETVHLIARAVRMFRMCTIEELKKVHTTIYTKAEKKVQLVIETTLAVAGTKNTIQHLIHHFEKKSITPLRAAELLKSVQETLYPSEHIADLLIQLAQSPLSEKYEPLRQSAWLAAGSVVRGFASKTQDLPLIRPASRQTKEKYVRVFMQHFRNADSTYEKVLALKTLGNAGIDLSVYELVQIIQDPRQPLSIRTEAVDALRLLKDVMPRKIQKVLLPVYKNRQNKPELRMAALWRMMHTIPEEPVLAHIVSQMENESNQHVAAFTYNVLRQFYKSTNPCYQQLAVRCSKILLFTRYQPQEQMLSTYSQLPLFNSEWLSGVQFDFATIFEKNAFLPKEVQASFETVFGGNWNKYFAQVGFSQQNFEQVILKTLEKLSLYGKQSDELRSRRVQSGIQMLQEIVKKMNIRPRVQQTDSQNAHAVFYLRYKEMDYIVLPIDMETIDTLVEKYVRNGEFDIKSLLTFLTNDSKFELHRALFFYEAERRIPTTIGMPLTISGKMPTILSINGKVSIELEKLGARLVLDIVPTVATTHVTEMRFWYPVIEQGVKSLQSARLHTPLRFESTVELKKNTLEITHKFVVPENKKTTVSVHTRPVAFIRVPKNQDSEYVEAEEKTISHSQYQMSTEEIDRQYETFGLRINAQGNVLSQWTLPMVLMTEQDFEYTLENKNRPVEFTARVTIGNLEKTDLSEIKFDKIFEKEFDLENNESENRRQYFHKMIREIQSEQGFKNLITLKLEAPQQMYWNTELRTVCDKWIRMCKVEMDARRSPMEHENKEWTLRTELLAARPQMPSSLRQLREQPHREVQLAFNAKWGSSKKSEITVNAQLEQSTEQKKFIRNIEREYKGIPEYELLIKAARLNQVNVVSEYKLTPQSEYTFSRIFDLIKAYNFWTVSEKRVQNENRRVVLQLSVEPLSRQYMNMTIQTPEQEVELKNVRIPRVVLPTIARSAMFQQTWEKTGATCKVDQSEVSTFDNVIYRAPLTTCYSLVAKDCSEQPRFAVLAKKINKNSEELLVKVVRREEEIVVKKSDDKFLVKVDGKKVNPTELEQYNIEILGDNLIVIRLPQGEVRFDGYTVKTNMPSVASQNQLCGLCGNNDGERDNEFMTADNYETEDVEEFHRSYLLKNEECEVENDRISEKKNYRNKWNREEKKSDYESSSDYESNYDEKETEKELVKKTLIKEFSNRVCFSIEPVSECRRGLESEKTSNKKIRFTCMPRHSKNARRFLKEAREQTVAELVDFPVSFVESVKIPTACVAY","length":1603,"molWeight":186439,"crc64":"00904A8F18BFB1B9","md5":"FA02771E60E805141AD3C8272ADD3735"},"extraAttributes":{"countByCommentType":{"FUNCTION":1,"SUBCELLULAR LOCATION":1,"TISSUE SPECIFICITY":1,"PTM":1,"DISRUPTION PHENOTYPE":1,"CAUTION":1},"countByFeatureType":{"Signal":1,"Chain":1,"Domain":2,"Region":1,"Disulfide bond":2,"Sequence conflict":14},"uniParcId":"UPI0000060EB2"}}